Clinical trials: Ocd
Obsessive-Compulsive Disorder
Deep Brain Stimulation for Refractory Obsessive-Compulsive Disorder
The goal of this clinical trial is to learn if deep brain stimulation (DBS) works to treat refractory obsessive-compulsive disorder (OCD).
- Trial name
- NCT06660225
- Testing
- Medtronic Percept Deep Brain Stimulation Therapy [Therapeutic stimulation]
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Nader Pouratian
Hoarding Disorder
Vortioxetine for the Treatment of Hoarding Disorder
The present study is a single-group open-label investigation of the potential efficacy of Vortioxetine for treatment of 30 adult volunteers with Hoarding Disorder (HD) (flexible-dose study, with a target dose range 5-25mg).
- Trial name
- NCT04035850
- Testing
- Vortioxetine Tablets
- Where
- Canada
- Sponsor
- Noam Soreni
Emotional Regulation, Depression
A Precision Medicine Approach to Target Engagement for Emotion Regulation
The proposed study is designed to first test whether teaching people personalized or standardized emotion regulation skills leads to greater decreases in daily negative emotion intensity.
- Conditions
- Emotional Regulation, Depression, Anxiety, Borderline Personality Disorder
- Trial name
- NCT05651295
- Testing
- Checking the Facts, Opposite to Emotion Action, Mindfulness of Current Emotions
- Where
- United States
- Volunteers
- 390 people
- Sponsor
- Matthew Southward, PhD
Obsessive Compulsive Disorder
A Cognitive Behavioral Therapy of Primary Obsessions in Obsessive Compulsive Disorder
A New Cognitive Behavioral Therapy to Target Distorted Appraisals Characteristic of Primary Obsessions in Obsessive Compulsive Disorder
- Trial name
- NCT00358995
- Testing
- Cognitive Behavioral Therapy, Stress Management Therapy (SMT)
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- University of British Columbia
Trichotillomania
Habit Reversal Training for Children and Adolescents With Trichotillomania
The purpose of the current study is: 1. To evaluate the effectiveness of a habit reversal training (HRT) approach for children ages 7 to 17 years of age inclusive with a diagnosis of trichotillomania. 2.
- Trial name
- NCT01445444
- Testing
- Habit Reversal Training
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of South Florida
Obsessive-Compulsive Disorder (OCD)
DBS for Obsessive-Compulsive Disorder
There are two primary approaches to the treatment of OCD, pharmacotherapy and cognitive behavior therapy (CBT). Lack of therapeutic success with one approach leads to trials of the alternative approach or a combination of the…
- Trial name
- DBS (NCT02773082)
- Testing
- Reclaim™ DBS Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Northwell Health
Mental Health Impairment
Pharmacogenetic Supported Prescribing in Kids
Implementation of pharmacogenetic testing for children and adolescents aged 6-24 who are starting or changing psychiatric medication.
- Trial name
- PGx-SParK (NCT04797364)
- Testing
- Pharmacogenetic Testing
- Where
- Canada
- Volunteers
- 6,000 people
- Sponsor
- University of Calgary
Obsessive-Compulsive Disorder
Evaluation of the Long Term Efficacy and Durability of the BrainsWay Deep TMS in OCD Subjects
A Prospective Double Blind Randomized Controlled Trial to Evaluate the Long Term Efficacy and Durability of the BrainsWay Deep Transcranial Magnetic Stimulation (Deep TMS) in Obsessive-Compulsive Subjects
- Trial name
- NCT05404360
- Testing
- BrainsWay Deep TMS HAC/H7-Coil
- Volunteers
- 124 people
- Sponsor
- Brainsway
Lateral Epicondylitis, Medial Epicondylitis
Investigation of Obsessive-Compulsive Disorder in Patients With Elbow Epicondylitis
This study will compare obsessive-compulsive symptoms in adults with medial and/or lateral elbow epicondylitis (pain and tenderness on the inner and/or outer side of the elbow).
- Conditions
- Lateral Epicondylitis, Medial Epicondylitis, Obsessive-Compulsive Symptoms
- Trial name
- NCT07906379
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Fatih Turkmensoy
Anxiety Disorders, Obsessive-Compulsive Disorder
Brief-intensive CBT Versus Once-weekly CBT in Anxiety-related Disorders
The goal of this clinical trial is to compare brief-intensive cognitive-behaviour therapy (CBT) with regular weekly CBT in people with anxiety-related disorders.
- Conditions
- Anxiety Disorders, Obsessive-Compulsive Disorder, Posttraumatic Stress Disorder, Hypochondriasis
- Trial name
- KOMMA (NCT05942391)
- Testing
- Cognitive behavioral therapy (CBT)
- Where
- 6 sites in Netherlands
- Volunteers
- 120 people
- Sponsor
- Amsterdam UMC, location VUmc
Obsessive-compulsive Disorder
Internet-based vs Face-to-face Cognitive Behavioural Therapy for Obsessive-compulsive Disorder
Randomized controlled non-inferiority trial comparing therapist-guided Internet-based Cognitive behavioral therapy (ICBT), self-guided ICBT, and individual face-to-face (f2f) CBT for Obsessive-Compulsive Disorder (OCD) in adults.
- Trial name
- NCT02541968
- Testing
- Cognitive-behavioral therapy (face-to-face), Internet-based Cognitive-behavioral therapy, Internet-based Cognitive-behavioral therapy without therapist support
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Karolinska Institutet
Obsessive-Compulsive Disorder, Obsessive-compulsive Disorders and Symptoms
Cognitive Bias Modification for OCD
This study will conduct the development and preliminary evaluation of Cognitive Bias Modification for Interpretation (CBM-I) and Approach Avoidance Training (AAT) as augmentations to treatment as usual for OCD and related…
- Trial name
- NCT03799419
- Testing
- Cognitive bias modification for interpretation bias, Psychoeducation, Approach avoidance training
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Mclean Hospital
Obsessive-Compulsive Disorder
Pilot Study of RR-HNK in OCD
The purpose of this study is to understand how RR-HNK works in the brain to bring about a reduction in OCD symptoms.
- Trial name
- (HNKO) (NCT06575075)
- Testing
- RR-HNK/Hydroxynorketamine
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Carolyn Rodriguez
Obsessive-Compulsive Disorder, Anxiety Disorders
Improving Access to Child Anxiety Treatment
There is strong evidence that cognitive behavioral therapy (CBT) with exposure is the preferred treatment for youth with anxiety disorders, but outpatient services that provide this type of treatment are limited.
- Conditions
- Obsessive-Compulsive Disorder, Anxiety Disorders, Pediatric Disorder, Anxiety
- Trial name
- IMPACT (NCT03528109)
- Testing
- Exposure Therapy
- Where
- United States
- Volunteers
- 379 people
- Sponsor
- Bradley Hospital
Obsessive-Compulsive Disorder
Mindfulness Meditation Utilizing an EEG Biofeedback Device for the Treatment for Obsessive Compulsive Disorder
The Frederick W. Thompson Anxiety Disorders Centre has experienced significant demand for services related to the treatment of Obsessive Compulsive Disorder (OCD), resulting in a significant wait time for service.
- Trial name
- NCT03273699
- Testing
- Mindfulness
- Where
- Canada
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Obsessive-Compulsive Disorder
Repetitive Transcranial Magnetic Stimulation in Obsessive Compulsive Disorder
Evaluate the therapeutic effect of a functional Magnetic Resonance Imaging (fMRI)-guided and robotized neuronavigated theta burst Transcranial Magnetic Stimulation (TMS) targeting right inferior frontal region in resistant…
- Trial name
- MAGTOC (NCT02884674)
- Testing
- Active Repetitive Transcranial Magnetic Stimulation
- Where
- France
- Volunteers
- 56 people
- Sponsor
- University Hospital, Grenoble
Major Depressive Disorder, Generalized Anxiety Disorder
The Modular Protocol for Mental Health (MPMH)
Currently, our best psychological treatments for anxiety and mood disorders only focus on individual diagnoses. So, there are separate treatments for Panic Disorder, or Depressive Disorder, or Social Anxiety, etc.
- Conditions
- Major Depressive Disorder, Generalized Anxiety Disorder, Posttraumatic Stress Disorder, Social Anxiety Disorder
- Trial name
- MPMH (NCT03143634)
- Testing
- The Modular Protocol for Mental Health, Treatment-as-usual
- Where
- United Kingdom
- Volunteers
- 43 people
- Sponsor
- Medical Research Council Cognition and Brain Sciences Unit
Obsessive-Compulsive Disorder
Imaging-Guided Low Intensity Focused Ultrasound (LIFU)
This research study is to investigate the safety, feasibility, and possible therapeutic benefits of a technology called Low Intensity Focused Ultrasound (LIFU) in patients with obsessive- compulsive disorder (OCD).
- Trial name
- LIFU (NCT05467085)
- Testing
- BX Pulsar 1002
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- Baylor College of Medicine
Obsessive Compulsive Disorder
Attention Training for Childhood Obsessive Compulsive Disorder: An Open Case Series
Pediatric Obsessive Compulsive Disorder (OCD) is a chronic, impairing condition that accrues significant concurrent and long-term risk to affected youth.
- Trial name
- AMPOCD (NCT01708226)
- Testing
- Attention Modification Program
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of California, Los Angeles
Obsessive-Compulsive Disorder
Deep Brain Stimulation in Severe Obsessive-compulsive Disorder
Deep brain stimulation is an established treatment for movement disorders. New indications for deep brain stimulation are under investigation, among them severe and treatment-resistant obsessive-compulsive disorder.
- Trial name
- DBS in OCD (NCT04919785)
- Testing
- Deep brain stimulation
- Volunteers
- 11 people
- Sponsor
- University Hospital, Umeå