Clinical trials: Ocular Anesthesia, active
Chronic Venous Insufficiency, CVI
The Use of Immersive Virtual Reality as a Method of Treating Anxiety and Procedural Pain During Endovenous Laser Ablation (EVLA) of Lower Varicose Veins Under Tumescent Anesthesia
This is a prospective, single-arm, pre-post interventional study designed to evaluate the feasibility, safety, and impact of immersive virtual reality (VR) as an adjunct to tumescent local anesthesia during endovenous laser…
- Trial name
- EVLA+VR (NCT07624929)
- Testing
- VR (VR-Control)
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Bydgoszcz University of Science and Technology
Topical Anaesthesia, General Anesthetic Drug Adverse Reaction
Evaluation of Postoperative Pain in Cases Undergoing Cataract Surgery Under Topical Versus General Anesthesia
Comparison between cataract surgery under local versus general anesthesia regarding postoperative pain, complications and patient satisfaction and need for rescue analgesic intake after surgery The results will be followed up at…
- Conditions
- Topical Anaesthesia, General Anesthetic Drug Adverse Reaction, Cataract
- Trial name
- NCT07287683
- Testing
- Topical Anaesthesia group, General Anaesthesia group
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Alexandria University
Virtual Reality, Eye Disease
Virtual Reality and Its Use in Reducing Perioperative Stress in Cataract Surgery
This project is to evaluate the benefits of utilising virtual reality (VR) headsets with the aim of reducing peri-operative anxiety in cataract surgery and hence reducing the need for sedation in patients with significant stress…
- Conditions
- Virtual Reality, Eye Disease, Cataract Surgery Anesthesia, Cataract Surgery
- Trial name
- NCT06822023
- Testing
- virtual reality mask
- Volunteers
- 75 people
- Sponsor
- South Tyneside and Sunderland NHS Foundation Trust
Squint Anaesthesia
Comparative Study Between Using Combined Propofol Sedation With subTenon's Infusion as Local Anaesthsia to the Eye Versus General Anesthesia for Strabismus Surgery in Adults
in this study investigators compare two type of anesthetic technique for squint surgery in adult patient first is general anesthesia versus local anesthesia using subtenon injection of local anesthetic.
- Trial name
- squint anaesth (NCT07504354)
- Testing
- sedation with subtenon injection of local anesthetic, General Anesthesia (control group)
- Volunteers
- 60 people
- Sponsor
- Sohag University
Vision; Disorder, Loss
The Influence of Prone Position for Spinal Surgery on Visual Acuity
This study investigated the effect of desflurane and propofol anesthesia on visual acuity in patients in prone position for spinal surgery.
- Trial name
- NCT03644641
- Testing
- Desflurane Group, Propofol Group
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- University Hospital Hradec Kralove
Retinoblastoma, Neurocognitive Dysfunction
Cognitive Functioning and Health Related Quality of Life in Retinoblastoma Survivors
A retrospective crosssectional observational study of the effects of oncological treatment and frequent general anesthesia on neuropsychological development, psychosocial functioning (in terms of anxiety, depression, peer…
- Conditions
- Retinoblastoma, Neurocognitive Dysfunction, Health-Related Behavior
- Trial name
- RbNeuroQoL (NCT06227962)
- Testing
- Neuropsychological assesment, Psychosocial functioning and quality of life (questionnaires), Parental psychosocial functioning (questionnaires)
- Where
- Netherlands
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Amsterdam University Medical Center
Pain, Perioperative
Reducing Pain From Retinal Laser With Vibrational Stimulation
The goal of this clinical trial is to learn if Vibration Anesthesia Device works to reduce pain during retinal laser for diabetic retinopathy.
- Trial name
- NCT06649604
- Testing
- Vibration Anesthesia Device, Panretinal Photocoagulation
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Alberta
Postoperative Delirium
Association of Optic Nerve Sheath Diameter and Postoperative Delirium
Postoperative delirium is a sudden and reversible disturbance of mental function, occurring after surgery, characterized by confusion, inattention, and fluctuating mental status, which can manifest as agitation or lethargy.
- Trial name
- NCT07249047
- Testing
- Optic nerve sheath diameter (ONSD) ultrasound
- Volunteers
- 300 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Postoperative Vomiting, Postoperative Nausea and Vomiting
Effect of Ketamine-Propofol Total Intravenous Anesthesia Versus Sevoflurane-Based Anesthesia on Postoperative Vomiting in Children Undergoing Strabismus Surgery
Pediatric strabismus surgery is frequently followed by postoperative nausea and vomiting, which can cause significant discomfort, dehydration, and delayed recovery in young children.
- Conditions
- Postoperative Vomiting, Postoperative Nausea and Vomiting, Strabismus
- Trial name
- NCT07871292
- Testing
- Ketamine and Propofol, Sevoflurane
- Volunteers
- 50 people
- Sponsor
- Assiut University
Congenital Glaucoma
Study Aim to Compare the Effect of Different Technique of Airway Managment During Anaesthesia on the Haemodynamics and Intraocular Pressure. Patients Were Divided Into Three Groups of 25 Patients Each. (Group A); Patients Who Were Subjected to LMA Insertion (Group B ).
this study aim to compare the effect of different technique of airway managment during anaesthesia on the haemodynamics and intraocular pressure in pediatric patient undergoing congenital glaucoma surgery.
- Trial name
- Airway and IOP (NCT07504315)
- Testing
- laryngeal mask insertion, I gel mask insertion, Endotracheal tube insertion
- Volunteers
- 75 people
- Sponsor
- Sohag University
Primary Open Angle Glaucoma, Pseudoexfoliation Glaucoma
Uddevalla Skövde Transscleral Micropulse Study
Micro pulse transscleral laser treatment (MP-TLT) is a relatively new method to reduce the intraocular pressure (IOP) in glaucoma.
- Trial name
- USTMS (NCT05557721)
- Testing
- Topical lidocaine, MP-TLT
- Where
- 2 sites in Sweden
- Volunteers
- 40 people
- Sponsor
- Vastra Gotaland Region
Cataract and IOL Surgery, Cataract Surgery Anesthesia
The Impact of Physiologic Cataract Surgery on Patient Comfort and Medication Usage
The study will pertain to investigating the impact of high vs low IOP on the intraoperative experience and comfort for the patient and surgeon.
- Conditions
- Cataract and IOL Surgery, Cataract Surgery Anesthesia, Cataract Surgery Experience, Nuclear Cataract
- Trial name
- NCT07223866
- Testing
- High IOP Setting, Low IOP Setting
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Matthew Rauen
Ophthalmology, Cataract Surgery Anesthesia
An Extension Test of Whether to Use Oral Anti-anxiety Drugs (Alprazolam) When Patients Choose Second Eye Cataract Surgery After Unblinding, and Analyze Their Anxiety, Satisfaction and Pain Satisfaction
Phacoemulsification is one of the most used surgical methods for cataract surgery today, and the surgeries are under the anesthetic and sedative to make it comfortable and safe for patients.
- Conditions
- Ophthalmology, Cataract Surgery Anesthesia, Oral Anxiolytic, Satisfaction Survey
- Trial name
- NCT06874452
- Testing
- Alprazolam (Xanax)
- Where
- Taiwan
- Volunteers
- 250 people
- Sponsor
- National Taiwan University Hospital
Post Dural Puncture Headache
Optic Nerve Sheath Diameter for Predicting Post-Dural Puncture Headache in Cesarean Section Patients
Some patients develop headache after spinal anesthesia used during cesarean section. This condition is called post-dural puncture headache (PDPH). Early identification of patients at risk may improve patient care.
- Trial name
- NCT07497945
- Testing
- Optic Nerve Sheath Diameter Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 220 people
- Sponsor
- Kocaeli University
Pediatric Retinoblastoma, Retinoblastoma
Determining Whether Multiple Anesthesia Exposures Affect Cognitive Function for Retinoblastoma Patients
The purpose of this study is to see if there is a difference between the development of the brain (neurodevelopment) in children who have been treated for retinoblastoma with multiple anesthetic exposures, compared with brain…
- Trial name
- NCT03546387
- Testing
- Wechsler Intelligence Scale for Children, Fifth Edition (WISC-V), California Verbal Learning Test, Children's Version, Beery Developmental Test of Visual Motor Integration, 6th edition
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cataract
Clinical Outcomes of Sedation in Cataract Surgery Performed Under Topical Anesthesia
This study aims to evaluate the clinical outcomes of different sedation strategies in patients undergoing cataract surgery performed under topical anesthesia.
- Trial name
- SADCAT (NCT07347886)
- Testing
- Normal Saline, Midalozam, Fentanyl (IV)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Istanbul University - Cerrahpasa
Epiretinal Membranes, Retinal Detachment
Subjective Pain Scoring for Subtenonal Anesthesia During Vitrectomy
Subtenonal anesthesia is a well-known technique of local anesthesia for patients undergoing pars plana vitrectomies. It was described to be efficient with respect to anesthesia of the eye and it showed less risks compared to…
- Conditions
- Epiretinal Membranes, Retinal Detachment, Full Thickness Macular Hole
- Trial name
- NCT06830070
- Testing
- subjective pain score assessment
- Where
- Austria
- Volunteers
- 70 people
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Cataract, Binaural Beats
Binaural Sound During Phacoemulsification and Posterior Chamber Lens Implantation in Geriatric Patients
The purpose of this study is to evaluate the effects of binaural beats on patient satisfaction and intraoperative comfort in patients aged 65 years or older undergoing cataract surgery (phacoemulsification and posterior chamber…
- Conditions
- Cataract, Binaural Beats, Geriatric Anesthesia
- Trial name
- NCT07609186
- Testing
- binaural beats
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Vision and Hearing Loss, Vision Impairment
SENSE-Brain Health Pro for Older Adults With Sensory Loss
The goal of this study is to learn about the outcomes, usability, and accessibility of the online Brain Health Pro program for older adults with hearing difficulties, vision difficulties, or both.
- Conditions
- Vision and Hearing Loss, Vision Impairment, Hearing Impairment, Vision Difficulty
- Trial name
- SENSE-BHPro (NCT07856888)
- Testing
- Brain Health Pro
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- Université de Montréal
Preeclampsia, Spinal Anesthesia-Induced Hypotension
Dexamethasone Versus Ondansetron for Preventing Post-Spinal Hypotension in Preeclampsia
This study compares the efficacy and safety of intravenous dexamethasone versus intravenous ondansetron in preventing low blood pressure (hypotension) following spinal anesthesia in pregnant women with preeclampsia undergoing…
- Conditions
- Preeclampsia, Spinal Anesthesia-Induced Hypotension, Cesarean Section
- Trial name
- NCT07793760
- Testing
- Dexamethasone, Ondansetron
- Volunteers
- 110 people
- Sponsor
- Assiut University