Clinical trials: Ocular Discomfort
Retina--Diseases, Retinal Detachment
Evaluation of Discomfort Associated With Scleral Depression During Retina Examinations
Scleral depression is an important technique used to examine the peripheral retina but often causes patient discomfort. The goal of this study was to compare levels of discomfort during scleral depression with a Schocket scleral…
- Conditions
- Retina--Diseases, Retinal Detachment, Retinal Degeneration
- Trial name
- DEPRESS (NCT04115917)
- Testing
- Schocket scleral depressor, Cotton tipped applicator
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- New York City Health and Hospitals Corporation
Contact Lens, Questionnaire
Chinese Translation and Validation of the 8-item Contact Lens Dry Eye Questionnaire (CLDEQ-8)
This is a cross-cultural adaptation, evaluation and validation study of the 8-item Contact Lens Dry Eye Questionnaire (CLDEQ-8) among soft contact lens wearers in China.
- Conditions
- Contact Lens, Questionnaire, Contact Lens Discomfort
- Trial name
- CLDEQ-8 (NCT05416528)
- Where
- China
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Dry Eye, Contact Lens Complication
Effects of Supplementation With PUFAs and Antioxidants for Contact Lens Discomfort
HydroEye® is a dietary omega 3 fatty acid supplement that contains both EPA and DHA, as well as GLA and ALA in the form of black currant seed oil.
- Trial name
- NCT04163328
- Testing
- HydroEye®
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Alabama at Birmingham
Dry Eye Disease (DED), Contact Lens Discomfort (CLD)
Treating Contact Lens Discomfort With Cyclosporine 0.1% Ophthalmic Solution
Of the 140 million contact lens (CL) wearers worldwide, most wear soft contact lenses. Despite major improvements in contact lens care, nearly 20% of wearers stop using lenses, with contact lens discomfort (CLD) being the main…
- Trial name
- NCT07904728
- Testing
- Cyclosporine 0.1% Ophthalmic Solution
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Ocular Aesthetics, LLC dba Ocular Clinical Trials
Dry Eye, Dry Eye Syndromes
Tangible Hydra-PEG: A Promising Solution for Scleral Lens Wearers With Dry Eye
Tangible Hydra-PEG is a novel coating technology designed to improve lens wettability, deposit resistance, and tear film breakup time.
- Trial name
- NCT03417505
- Testing
- Scleral lenses treated with Tangible Hydra-PEG, Untreated scleral lenses
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- Tangible Science
Dry Eye, Contact Lens Discomfort
Contact Lens-Wearing Dry Eye Subjects Who Are Treated With Acoltremon 0.003%
Dry Eye Disease is a multifaceted condition which has symptoms such as eye dryness, burning, and stinging sensation in the eyes. As well as clinical diagnosis such as a decreased ability to create tear film.
- Conditions
- Dry Eye, Contact Lens Discomfort, Eye Drops
- Trial name
- NCT07848373
- Testing
- acoltremon 0.003%
- Volunteers
- 50 people
- Sponsor
- Eye Research Associates, LLC
Migraine, Photophobia
Impact of Optimized White Light on Visual Discomfort, Headache Intensity, and Cognitive Performance Among Those With Migraine
The goal of this research is to study how effective an optimized white light is for improving visual comfort and reducing migraine symptoms.
- Conditions
- Migraine, Photophobia, Cognitive Function Assessment, Headache
- Trial name
- NCT07898722
- Testing
- Optimized Ambient White Light, Conventional White Light
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Dry Eye
LME636 in the Relief of Persistent Ocular Discomfort in Subjects With Severe Dry Eye Disease
The purpose of this study is to evaluate the efficacy of LME636 compared to vehicle in the reduction of ocular symptoms and to evaluate the safety and tolerability of LME636, when administered topically for up to 42 days, in…
- Trial name
- NCT02365519
- Testing
- LME636 ophthalmic solution, LME636 Vehicle
- Volunteers
- 514 people
- Sponsor
- Alcon, a Novartis Company
Post Laser Vision Correction Pain and Discomfort
Laser Vision Correction Use of an Eye Shield for Maintaining Vision and Mitigating Pain
The purpose of this research is to determine if an investigational thin shield can effectively reduce discomfort following Laser Vision Correction.
- Trial name
- NCT01675375
- Testing
- Eye Shield
- Where
- 5 sites in United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- FORSIGHT Vision3
Dry Eye Disease
Evaluation of Anti-Inflammatory Treatment in Dry Eye Patients
The purpose of this study was to determine if difluprednate ophthalmic emulsion is effective in reducing the ocular symptoms of dry eye disease, as measured by a global Visual Analog Scale (VAS) discomfort score.
- Trial name
- NCT01276223
- Testing
- Difluprednate 0.05% ophthalmic emulsion, Difluprednate vehicle
- Where
- United States
- Volunteers
- 722 people, healthy volunteers welcome
- Sponsor
- Alcon Research