Clinical trials: Ocular Diseases
Giant Cell Arteritis, Takayasu's Arteritis
Reproductive Health in Men and Women With Vasculitis
The purpose of this study is to learn about reproductive health, including fertility and pregnancies, in people with vasculitis.
- Conditions
- Giant Cell Arteritis, Takayasu's Arteritis, Polyarteritis Nodosa, Wegener's Granulomatosis
- Trial name
- NCT02176070
- Where
- United States
- Volunteers
- 467 people
- Sponsor
- University of South Florida
Macular Edema, Retinal Vein Occlusion
Fluocinolone Acetonide Intravitreal Inserts for Vein Occlusion in Retina
This study will assess the safety and efficacy of FA Intravitreal Inserts in subjects with macular edema secondary to RVO.
- Trial name
- FAVOR (NCT00770770)
- Testing
- Fluocinolone Acetonide
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- Alimera Sciences
Multi-drug Resistant Tuberculosis, Extensively Drug Resistant Tuberculosis
TBTC Study 30: Safety and Tolerability of Low Dose Linezolid in MDR TB
This study evaluated the safety and tolerability of low-dose linezolid (600 mg once daily) administered for 16 weeks as part of an optimized background regimen for the treatment of multidrug-resistant tuberculosis (MDR-TB).
- Trial name
- LiMiT (NCT00664313)
- Testing
- Linezolid
- Where
- South Africa
- Volunteers
- 36 people
- Sponsor
- Centers for Disease Control and Prevention
Presbyopia
Clinical Outcome of Extended-depth-of-focus Trifocal Intraocualr Lens (Triumf) Implantation
Clinical outcome of extended-depth-of-focus trifocal intraocualr lens (Triumf) implantation
- Trial name
- NCT04392024
- Testing
- Triumf
- Where
- South Korea
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Glaucoma
A Phase 3 Prospective, Randomized, Double-Masked, 12-Week, Parallel Group Study In Pediatric Subjects With Glaucoma.
To assess the effectiveness of latanoprost 0.005% ophthalmic solution dosed once-daily and timolol 0.5% dosed twice-daily in paediatric subjects of 18 years of age or under who are diagnosed with glaucoma.
- Trial name
- NCT00716859
- Testing
- Timolol, latanoprost
- Where
- 48 sites in United States, Belgium and 18 more
- Volunteers
- 139 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Myopia, Child Myopia Progression
Effect of MiYOSMART iQ Spectacle Lenses on Myopia Progression in Children
This prospective, single-center study aims to evaluate the efficacy and safety of MiYOSMART iQ spectacle lenses with DIMS (Defocus Incorporated Multiple Segments) and Triple Enhanced Design (TED) technology in slowing myopia…
- Trial name
- NCT07387159
- Testing
- MiYOSMART iQ spectacle lenses
- Where
- Russia
- Volunteers
- 70 people
- Sponsor
- Hoya Lens Rus LLC
Cataract
Visual Performance of the Vivity IOL in Post-myopic LASIK and PRK Patients
The objective is to evaluate visual outcomes and patient satisfaction in patients with a history of myopic LASIK or PRK who will have completed cataract surgery with the Vivity IOL.
- Trial name
- NCT05961046
- Testing
- Vivity IOL
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Laser & Corneal Surgery Associates
Dry Eye Syndromes
Study of Two Formulations of Cyclosporine Ophthalmic Emulsion in Healthy Volunteers and in Patients With Dry Eye
This study will evaluate the safety, tolerability and pharmacokinetics of two formulations of cyclosporine ophthalmic emulsion in healthy adults (parallel-group phase).
- Trial name
- NCT01319773
- Testing
- cyclosporine ophthalmic emulsion Formulation A, cyclosporine ophthalmic emulsion Formulation B, cyclosporine ophthalmic emulsion Formulation A; cyclosporine ophthalmic emulsion 0.05%
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Allergan
Trichiasis
Comparison of Argon Laser and Radiofrequency in Trichiasis Treatment
In this clinical trial study,the investigators intend to compare two methods of trichiasis treatment.One by argon laser and the other by radiofrequency then compare the result of these procedures, especially, the investigators…
- Trial name
- NCT00776269
- Testing
- argon laser and radiofrequency
- Where
- Iran
- Sponsor
- Shahid Beheshti University of Medical Sciences
Retinitis Pigmentosa (RP)
Investigation of Therapeutic Efficacy and Safety of UMSCs for the Management of Retinitis Pigmentosa (RP)
Retinitis pigmentosa (RP) is the most common hereditary retinal disorder (accounts for 20% of children attending blind schools in Pakistan) which causes degeneration of rod and cone photoreceptors.
- Trial name
- NCT04763369
- Testing
- Injection of stem cells in sub-tenon space of eye for the management of retinitis pigmentosa, Injection of stem cells in suprachoroidal space of eye for the management of Retinitis Pigmentosa
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Jinnah Burn and Reconstructive Surgery Centre, Lahore
Allergic Rhinitis
Effect of Veramyst on the Nasal and Ocular Symptoms of the Early Reaction to Nasal Challenge With Allergen
The purpose of this study is to help us to a better understanding of how nose and eye symptoms are related in patients with allergies.
- Trial name
- NCT00791973
- Testing
- fluticasone furoate
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Ocular Infection, Viral
Can COVID-19 Persist in Intraocular Fluid?
Several common viruses thrive and persist in intraocular fluid due to ocular immune privilege. Immune privilege is maintained by lack of lymphatic tissue, a strong blood ocular barrier, and regulation of the systemic immune…
- Trial name
- NCT04945850
- Testing
- routine care intraocular sx
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Myopic Astigmatism
A Study to Investigate the Safety and Effectiveness of the Technolas® TENEO 317 Model 2 Excimer Laser for Laser In Situ Keratomileusis (LASIK) Surgery to Treat Myopia or Myopic Astigmatism
This will be a multicenter, prospective, open label, non-randomized, single arm study evaluating the safety and effectiveness of the Technolas® TENEO 317 Model 2 (version 1.28 US software) Excimer Laser when used in LASIK surgery…
- Trial name
- NCT07377474
- Testing
- TENEO 317 Model 2 (1.28 US) Excimer Laser
- Volunteers
- 32 people
- Sponsor
- Bausch & Lomb Incorporated
Lysosomal Storage Disease, Lung Diseases
Biomarker for Maroteaux-Lamy Disease (BioMaroteaux)
Development of a new MS-based biomarker for the early and sensitive diagnosis of Maroteaux-Lamy disease from blood
- Conditions
- Lysosomal Storage Disease, Lung Diseases, Obstructive Sleep Apnoea, Macroglossia
- Trial name
- BioMaroteaux (NCT01458613)
- Where
- 5 sites in Egypt, Germany and 2 more
- Sponsor
- CENTOGENE GmbH Rostock
Dry Eye
Efficacy, Tolerability, and Comfort of 0.3% Hypromellose Eyedrops in Patients Undergoing LASIK Surgery
This study is designed to assess the tolerability and comfort of peri-operative 0.3% hypromellose eye drops in LASIK surgery patients and to assess whether pre-operative 0.3% hypromellose eye drops add to post-operative comfort…
- Trial name
- NCT00909324
- Testing
- Pre-LASIK 0.3% hypromellose, Post-LASIK 0.3% hypromellose
- Where
- India
- Volunteers
- 170 people
- Sponsor
- Novartis Pharmaceuticals
Optic Atrophy
Study the Safety and Efficacy of Bone Marrow Derived Autologous Cells for the Treatment of Optic Nerve Disease
This is a Single arm, Single centre trial to check the safety and efficacy of bone marrow derived autologous mono nuclear cell(100 millions per dose )clinical trial to be conducted for 36 months in patients with optic nerve…
- Trial name
- OND (NCT01834079)
- Testing
- STEM CELL THERAPY
- Where
- India
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Chaitanya Hospital, Pune
Dry Eye Syndrome
Comparison of Autologous Serum and Umbilical Cord Serum Eyedrops for Dry Eye Syndrome
To compare the therapeutic effect between autologous serum and umbilical cord serum eyedrops in the treatment of severe dry eye syndrome.
- Trial name
- NCT00442273
- Testing
- Umbilical cord serum eyedrops, Autologous serum eyedrops
- Where
- South Korea
- Sponsor
- Chonnam National University Hospital
Cataract
Comparison of In-the-bag Stability Between Single-piece and Three-piece Intraocular Lens
Rapid advances of cataract surgery techniques and intraocular lens (IOL) technology have enabled the transition of cataract surgery from blindness relief to refractive correction.
- Trial name
- NCT02609997
- Testing
- Phacomulsification lens removal cataract surgery with single-piece Intraocular lens(IOL) implantation, Phacomulsification lens removal cataract surgery with three-piece Intraocular lens(IOL) implantation, Subconjunctival dexamethasone
- Where
- China
- Volunteers
- 65 people
- Sponsor
- Sun Yat-sen University
Ptosis, Eyelid
Phenylephrine Versus Eyelid Taping for Muller's Muscle-Conjunctival Resection (MMCR) Evaluation
This research study aims to compare whether Phenylephrine 2.5% ophthalmic eye drop solution can serve as a better indicator of the effect of a drooping upper eyelid (ptosis) by covering part of the upper portion of the field of…
- Trial name
- NCT05890027
- Testing
- Phenylephrine Ophthalmic, Eyelid Tape
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Miami
Primary Open-angle Glaucoma, Low Tension Glaucoma
Metabolomics in Surgical Ophthalmological Patients
Metabolomics consists in the study of metabolites in body fluids or tissues. It investigates the consequences of the activity of genes and proteins.
- Trial name
- MISO (NCT03098316)
- Testing
- Metabolomics analysis of patient samples
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.