Clinical trials: Ocular Hypertension Glaucoma
Normal Tension Glaucoma
Systemic Glutathione Level in Normal Tension Glaucoma
The purpose of this study is to evaluate whether systemic glutathione level is decreased in patients with normal tension glaucoma.
- Trial name
- NCT00570362
- Where
- South Korea
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Glaucoma Eye, Glaucoma
Comparison of Fixation Suture Type in Glaucoma Surgery
The aim of the study is to compare the effectiveness and safety of two types of intraoperative eye fixation: for the superior rectus muscle and traction suture in the peripheral cornea.
- Trial name
- NCT03797846
- Testing
- combined glaucoma surgery
- Where
- Poland
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Glaucoma, Open-Angle, Ocular Hypertension
A Study of Bimatoprost in the Treatment of Primary Open Angle Glaucoma and Ocular Hypertension
This is a study of bimatoprost as initial, replacement, or adjunctive intraocular pressure (IOP)-lowering therapy in patients with primary open angle glaucoma and ocular hypertension.
- Trial name
- LOTUS (NCT02061683)
- Testing
- Bimatoprost 0.03%
- Where
- China
- Volunteers
- 263 people
- Sponsor
- Allergan
Glaucoma
Role of Polymorphisms in the IL-1 Gene Cluster
Glaucoma, an optic neuropathy characterized by progressive visual field loss, is the leading cause of irreversible blindness worldwide.
- Trial name
- NCT00346541
- Where
- Singapore
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Ocular Hypertension, Open Angle Glaucoma
A Study Evaluating the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open-Angle Glaucoma
The purpose of this study is to test if latanoprost punctal plugs will reduce eye pressure in subjects with ocular hypertension or open-angle glaucoma.
- Trial name
- NCT01229982
- Testing
- Latanoprost-PPDS
- Where
- Canada
- Volunteers
- 121 people
- Sponsor
- Mati Therapeutics Inc.
Glaucoma, Cataract
IOP and Ocular Biometrics Changes After Phacoemulsification in Glaucoma Patients and Controls
Effect of phacoemulsification on intraocular pressure has been studied with variable results.Furthermore, effect of phacoemulsification on ocular biometrics including anterior chamber depth and angle opening distance has also…
- Trial name
- NCT04334473
- Testing
- phacoemulsification and Intraocular lens implantation, Ultrasound Biomicrosopy (UBM)
- Where
- Egypt
- Volunteers
- 37 people
- Sponsor
- Mai Nasser Abd Elmohsen
Glaucoma
Evaluating Injection With the Use of Brimonidine Tartrate Ophthalmic 0.025% on Patients Using Netarsudil 0.02%/Latanoprost 0.005% to Treat Glaucoma
To evaluate the effect of brimonidine tartrate 0.025% on conjunctival hyperemia in patients treated with netarsudil 0.02%/latanoprost 0.005% mono-therapy for intraocular pressure lowering.
- Trial name
- NCT07209410
- Testing
- Brimonidine Tartrate Ophthalmic 0.025%
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Insight Eyecare Specialties, Inc. dba Vision Source Eyecare,
Primary Open Angle Glaucoma (POAG), Ocular Hypertension (OHT)
REGN22530 for Adults With Primary Open Angle Glaucoma or Ocular Hypertension
This study will test an experimental drug called REGN22530 ("study drug") to see if it can help treat people with primary open angle glaucoma or ocular hypertension.
- Trial name
- BAHAMA (NCT07675824)
- Testing
- REGN22530
- Where
- United States
- Volunteers
- 271 people
- Sponsor
- Regeneron Pharmaceuticals
Primary Open Angle Glaucoma, Ocular Hypertension
Non-inferiority of PRO-122 Ophthalmic Solution vs KRYTANTEK Ofteno® in Glaucoma or Ocular Hypertension (CONFORTK)
Aim: To demonstrate the non-inferiority of the PRO-122 ophthalmic solution manufactured by Laboratorios Sophia S.A. de C.V. versus Krytantek Ofteno® ophthalmic solution like hypotensive therapy in subjects with primary open angle…
- Trial name
- CONFORTK (NCT03257813)
- Testing
- PRO-122, Krytantek Ofteno®
- Volunteers
- 60 people
- Sponsor
- Laboratorios Sophia S.A de C.V.
Glaucoma, Intraocular Pressure
IOP Reduction After Anecortave Acetate Injection in Glaucoma Patients
Introduction: Ocular administration of glucocorticoids is a common and effective treatment for several ocular diseases. However it is often complicated with the elevation of intraocular pressure (IOP).
- Trial name
- NCT00533962
- Testing
- Anterior Juxtascleral Depot of Anecortave Acetate
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Federal University of São Paulo
Open-Angle Glaucoma, Ocular Hypertension
A Phase 3b Study Evaluating the 24-Hour Intraocular Pressure Lowering Effect of Bimatoprost SR in Patients With Open-Angle Glaucoma or Ocular Hypertension
This study will evaluate the 24-hour intraocular pressure lowering effect and safety after a single administration of Bimatoprost SR in patients with Open-Angle Glaucoma or Ocular Hypertension
- Trial name
- NCT04285580
- Testing
- Bimatoprost SR, LUMIGAN
- Where
- 6 sites in United States
- Volunteers
- 37 people
- Sponsor
- AbbVie
Glaucoma
Trabeculectomy With Subconjunctival Bevacizumab Injection
The purpose of this study is to investigate the safety and efficacy of bevacizumab as an adjunctive treatment to trabeculectomy in open angle glaucoma patients and to compare this new drug to the most commonly used anti-scarring…
- Trial name
- NCT01310764
- Testing
- Trabeculectomy
- Where
- Iran
- Volunteers
- 36 people
- Sponsor
- Rassoul Akram Hospital
Glaucoma
Study of Application of Pulse Electrical Stimulation Around Eye in Glaucoma Patients
This study aims to evaluate the efficacy and safety of applying pulse electrical stimulation around eyes of glaucoma patients.
- Trial name
- NCT05159414
- Testing
- Pulse Electrical Stimulation
- Where
- South Korea
- Volunteers
- 18 people
- Sponsor
- Nu Eyne Co., Ltd.
Glaucoma Capsulare, Genetic Predisposition to Disease
Genetic and Risk Factors in Exfoliation Glaucoma Patients
Prospective non-randomised cohort study enrolling patients with exfoliation glaucoma. All patients were ophthalmological examined at inclusion. Blood samples were taken for genetic analysis.
- Conditions
- Glaucoma Capsulare, Genetic Predisposition to Disease, Risk Reduction
- Trial name
- NCT06237764
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 130 people
- Sponsor
- Göteborg University
Glaucoma, Choroidal Effusions
Triamcinolone Injections for Persistent Choroidal Effusions Post Glaucoma Surgery
During glaucoma surgery, a new opening is created that allows fluid to drain out of the eye, bypassing the clogged drainage channels that are malfunctioning in patients with glaucoma.
- Trial name
- TRICEPS (NCT02917564)
- Testing
- Triamcinolone Acetonide 1 ml of 40 mg/mL suspension
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Sunnybrook Health Sciences Centre
Glaucoma, Open-Angle Ocular Hypertension
A Comparison of Bimatoprost SR to Selective Laser Trabeculoplasty in Patients With Open-Angle Glaucoma or Ocular Hypertension
This study will evaluate the intraocular pressure (IOP)-lowering effect and safety of Bimatoprost SR compared with selective laser trabeculoplasty in participants with open-angle glaucoma or ocular hypertension who are not…
- Trial name
- NCT02636946
- Testing
- Bimatoprost SR, Selective Laser Trabeculoplasty
- Where
- 33 sites in United States, Australia and 7 more
- Volunteers
- 144 people
- Sponsor
- Allergan
Open Angle Glaucoma, Eye Diseases
Effect of Repeated Low-Level Red-Light Therapy on Visual Field Damage in Primary Open-angle Glaucoma
The purpose of this study is to investigate the effect of repeated low-level red-light therapy on existing visual field damages in primary open-angle glaucoma patients.
- Trial name
- NCT05309811
- Testing
- RLRL therapy, Routine IOP-lowering medications
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Glaucoma
Direct Application of Selective Laser Trabeculoplasty in Open Angle Glaucoma
The trial objectives are to establish the safety \& efficacy of using a DLTP laser to perform laser trabeculoplasty to reduce Intraocular Pressure (IOP) in patients with open angle glaucoma (Including Pigmentary \& Exfoliative…
- Trial name
- NCT01383525
- Testing
- Direct Selective Trabeculoplasty device
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- BelkinVision
Conjunctiva, Cornea
MicroPulse Transscleral Laser Therapy and Its Short-term Impact on Ocular Surface
MicroPulse transscleral laser therapy (TLT) is proven to be effective in reducing intraocular pressure with minimal complications in either primary or secondary glaucoma.
- Trial name
- NCT06353776
- Testing
- conjunctival biopsy after micropulse transscleral laser therapy
- Where
- Tunisia
- Volunteers
- 15 people
- Sponsor
- University Tunis El Manar
Neurodegenerative Diseases
Citicoline Concentration in Human Vitreous
Elegible patients were included in the study and underwent treatment with a solution of citicoline 1% eye-drops, 0.2% high molecular weight hyaluronic acid and 0.01% benzalkonium chloride prior to surgery.
- Trial name
- NCT04003090
- Testing
- Citicoline
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Istituto di Ricerca Neuroftalmologia S.r.l.
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