Clinical trials: Ocular Pathologies
Intellectual Disabilities
Reading Intervention for Children With Intellectual Disabilities Who Require Augmentative and Alternative Communication
The goal of this multiple single case study with multiple randomized baseline (with four starting points and 18 measurements across time) is to conduct a reading intervention for 40 children with intellectual disabilities who…
- Trial name
- NCT05709405
- Testing
- Reading intervention
- Where
- 2 sites in Norway
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ostfold University College
Vertigo, Dizziness
Effectiveness of Osteopathic Manipulative Treatment (OMT) and Vestibular Rehabilitation Therapy (VRT) in Individuals With Vertigo
Western University of Health Sciences is seeking men and women to participate in a study on the effectiveness of Osteopathic Manipulative Treatment (OMT) and Vestibular Rehabilitation Therapy (VRT) in patients with vertigo.
- Conditions
- Vertigo, Dizziness, Benign Paroxysmal Positional Vertigo, Labyrinthitis
- Trial name
- NCT01529151
- Testing
- Osteopathic Manipulative Treatment (OMT), Vestibular Rehabilitation Therapy (VRT)
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Western University of Health Sciences
Colorectal Neoplasms, Colonic Polyp
Adenoma Detection Rate Using Endocuff Vision in China
The primary aim of this study is to explore the usefulness of Endocuff Vision in colonoscopy on adenoma detection rate (ADR). Other aims include to explore the data below when Endocuff Vision is used.
- Conditions
- Colorectal Neoplasms, Colonic Polyp, Adenoma
- Trial name
- SinoEVADR (NCT03839277)
- Testing
- Endocuff Vision
- Where
- 5 sites in China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Myopia
The Role of SNP of ECM and MMP on the Development of Pathological High Myopia
To study the clinical characteristics and inheritance of pathological myopia in Taiwanese patients.
- Trial name
- NCT00172952
- Where
- Taiwan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Ocular Pain
Evaluate the TetraLens, a Tetracaine Releasing Therapeutic Bandage Contact Lens in Patients Undergoing PRK Procedure
The goal of this clinical trial is to determine the safety, efficacy, and comfort of the investigational TetraLens bandage contact lens in patients who have undergone photorefractive keratectomy (PRK).
- Trial name
- NCT06085352
- Testing
- TetraLens bandage contact lens, Control Acuvue Oasys Bandage contact Lens
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Vance Thompson Vision
Retinopathy of Prematurity, Diabetic Retinopathy
Optical Coherence Tomography Angiography (OCT-A) in Children (≥ 6 <14 Years of Age)
Comparison of OCTA to conventional imaging modalities for the diagnosis of eye diseases in children
- Trial name
- OCTAC (NCT03399825)
- Testing
- OCT-A
- Volunteers
- healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Amblyopia
5 Years of Eye Screening for ARF in Children Aged <3 Years in Flanders
Researchers will investigate the distribution and evolution of amblyopia risk factors and other refractive errors in children younger than 3 years of age.
- Trial name
- NCT05612568
- Where
- Belgium
- Volunteers
- 250,000 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Emergencies
Comparison of Hands-on Versus Online Learning About Ocular Ultrasound
In patients who visit an emergency room with ocular symptoms, point-of-care ultrasound can quickly identify several emergency diseases.
- Trial name
- NCT04834700
- Testing
- online group
- Where
- South Korea
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Glaucoma, Corneal Transplantation
Inflammatory Mediators of Glaucoma After Corneal Transplantation (AH-Tears)
Glaucoma is the most common threat to vision rehabilitation in patients with Boston keratoprosthesis type 1 (KPro) implantation.
- Conditions
- Glaucoma, Corneal Transplantation, Inflammation
- Trial name
- AH-Tears (NCT04339907)
- Testing
- Sampling of tears, Sampling of aqueous humor
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Presbyopia, Pseudophakia
Identification of Minimum Focal Points in Vision Curve Formation
The primary objective of this study is to identify how many focal points and at which distances are necessary for reliable visual curve formation and area of the curve (AoC) calculation using mathematical models and comparing the…
- Conditions
- Presbyopia, Pseudophakia, Cataract, Refractive Errors
- Trial name
- NCT06260852
- Testing
- Diagnostic Test: Visual Acuity Assessment
- Where
- Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Corneal Neovascularization
Clinical Evaluation of Safety and Tolerability of KDR2-2 Eye Drops in Healthy Volunteers With Pharmacokinetic Assessment
A Phase 1 randomized, double blinded, placebo-controlled, single dose escalation (SDE) and repeat dose escalation (RDE) study to evaluate safety and tolerability, and PK of KDR2-2 in healthy volunteers.
- Trial name
- NCT04620109
- Testing
- KDR2-2
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Guangzhou HuiBoRui Biological Pharmaceutical Technology Co. Ltd
Neurodegenerative Disease, Behavioral Variant Frontotemporal Dementia (bvFTD)
Tracking and Predicting How Brain Damage Spreads in Neurodegenerative Diseases
Neurodegenerative diseases, including frontotemporal lobar degeneration (FTLD) spectrum syndromes, are characterized by the accumulation of insoluble protein aggregates in the central nervous system.
- Conditions
- Neurodegenerative Disease, Behavioral Variant Frontotemporal Dementia (bvFTD), Primary Progressive Aphasia(PPA), Progressive Supranuclear Palsy(PSP)
- Trial name
- NCT07567664
- Testing
- 3 Tesla MRI without contrast medium, Blood sample for genetic analysis, Cerebrospinal fluid sampling (CSF)
- Where
- Italy
- Volunteers
- 645 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Uveitis, Conjunctivitis
Ocular Manifestations in Rheumatic Diseases
This is a search strategy for determining the prevalence of ocular complications in inflammatory rheumatic diseases for the purposes of a meta analysis.
- Conditions
- Uveitis, Conjunctivitis, Keratoconjunctivitis Sicca, Xerophthalmia
- Trial name
- NCT03753893
- Testing
- No intervention used
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Low Vision, Fall
Increasing the Accessibility of a Falls Prevention Intervention for Community Dwelling Older Adults With Low Vision
This study serves to test a previously evaluated falls prevention intervention recommended by the Centers for Disease Control and Prevention, entitled the Study of Accidental Falls in the Elderly (SAFE) Health Behavior and…
- Trial name
- NCT03028493
- Testing
- Original SAFE Intervention, Adapted SAFE Intervention
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Sarah Blaylock
Rare Fetal Genetic Diseases, Congenital Malformation
Characterization and Contribution of Genome-wide DNA Methylation (DNA Methylation Episignatures) in Rare Diseases With Prenatal Onset
It is necessary to define reference DNA Methylation Episignatures from fetal DNA. The hypotheses are: It is possible to define reference DNA Methylation Episignatures from fetal DNA extracted from amniotic fluid or frozen tissues…
- Trial name
- FOETEPISIGN (NCT06475651)
- Testing
- Methylation analysis
- Where
- France
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Choroidal Neovascularization
Safety Study of Ranibizumab Eye Injections to Treat Choroidal Neovascularization That Was Caused Other Than by Age-Related Macular Degeneration.
The purpose of this study is to determine whether ranibizumab is effective in the treatment of choroidal neovascularization secondary to causes other then wet macular-degeneration.
- Trial name
- NCT00395551
- Testing
- ranibizumab
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ophthalmic Consultants of Boston
Surgical Smoke Exposure, Occupational Exposure to Surgical Smoke
THE EFFECT OF SURGICAL MASK AND N95 MASK USE ON SURGICAL SMOKE IN OPERATING ROOM NURSES
This study was conducted to compare the effect of surgical mask and N95 mask use on physical symptoms due to surgical smoke in operating theatre nurses.
- Conditions
- Surgical Smoke Exposure, Occupational Exposure to Surgical Smoke, Headache, Dizziness
- Trial name
- NCT07404956
- Testing
- Surgical Mask, N95 Mask
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Conjunctivitis, Allergic
OJO-miR: microRNA Expression in Allergic Conjunctivitis.
Allergic conjunctivitis (AC) causes inflammation of the conjunctiva in response to environmental allergens, affecting a significant percentage of the world population and reducing quality of life.
- Trial name
- OJO-miR (NCT07385495)
- Where
- Mexico
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Recurrent Ptosis of the Breast
Seri Surgical Scaffold Support of the Lower Pole of the Breast
Will the use of an FDA approved highly purified silk scaffold; Seri Surgical Scaffold help shape and hold the breast up on the chest preventing re-stretching and bottoming out of the breast in breast reduction or…
- Trial name
- SeriSupport (NCT02016612)
- Testing
- Seri Surgical Scaffold
- Where
- 2 sites in United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Bengtson Center
Coronary Heart Disease, Stroke
Hamburg City Health Study - a German Cohort Study
The Hamburg City Health Study (HCHS) is a large, prospective, long-term, population-based cohort study and a unique research platform and network to obtain substantial knowledge about several risk and prognostic factors in major…
- Conditions
- Coronary Heart Disease, Stroke, Dementia, Cancer
- Trial name
- HCHS (NCT03934957)
- Where
- Germany
- Volunteers
- 45,000 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf