Clinical trials: Ocular Prostheses
Paralysis, Paralysis; Eye
Evaluate the Usability of the Neuro-trigger Artificial Eye Blinking Stimulation Device in Patients With Paralysis of the Facial Nerve.
This is a single-center, open-label clinical study. Up to 11 subjects will be enrolled to use the Neuro-trigger device for blinking stimulation for a duration of 14 days.
- Conditions
- Paralysis, Paralysis; Eye, Paralysis; Bell
- Trial name
- paralysis (NCT06069128)
- Testing
- Neurotrigger Basic. eye blinking stimulator
- Where
- Israel
- Volunteers
- 11 people
- Sponsor
- Neurotrigger Ltd
Inflammatory Reaction Due to Ocular Lens Prosthesis
Efficacy and Safety Study of IBI-10090 in Patients Undergoing Cataract Surgery
This study will test the efficacy and safety of IBI-10090 for the reduction of ocular inflammation after cataract surgery.
- Trial name
- NCT01048593
- Testing
- IBI-10090
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- ICON Bioscience Inc
Blepharoptosis
Custom Print Megnetic Levator Prosthesis Pilot Comparison
Study the device feasibility of non-surgical treatment for blepharoptosis (inability to open the eyelid) consisting of a biocompatible magnetic element adhered to the upper eyelid and a second magnet above the eye on a custom…
- Trial name
- NCT04807855
- Testing
- The cMLP device
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Skelmet Inc
Enucleated; Eye
Digital Imaging Assessment of Ocular Prosthesis Motility
This study will evaluate the degree of translational movement loss from orbital implant to ocular prosthesis. This will be measured using two software applications - Image J as well as the mediGrid smartphone app in measuring…
- Trial name
- OCUPEYE (NCT03819621)
- Testing
- IRISS Medical Technologies mediGrid app
- Where
- United Kingdom
- Volunteers
- 57 people
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust
Age - Related Macular Degeneration (AMD)
International Study of the SING IMT™ Prosthesis in Pseudophakic patiEnts With Stable Moderate to Profound Bilateral Central vIsion Impairment Due to adVancEd AMD / PERSPECTIVE Study
This study aims to expand the CE mark IFU of the SING IMT™ to pseudophakic (patients with an intraocular lents) patients with late stage of AMD (Age-Related Macular Degeneration) and bilateral central vision impairment.
- Trial name
- PERSPECTIVE (NCT07164378)
- Testing
- Lens-Exchange, Add-on
- Where
- 12 sites in France, Germany and 1 more
- Volunteers
- 44 people
- Sponsor
- VisionCare, Inc.
Retinitis Pigmentosa
Argus II/ORCAM Device Study
This study is being done to determine if wearable text-to-speech (TTS) and visual pattern recognition (VPR) technology can be used to extend the capabilities of the Argus II to allow patients to read and recognize faces and…
- Trial name
- NCT03248388
- Testing
- Argus II Eyeglasses, ORCAM
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Mayo Clinic
Age Related Macular Degeneration
Study of WA-NG (NG-IMT) Telescope Prosthesis in Patients With End-stage Age-related Macular Degeneration
The purpose of this study is to evaluate the safety of the updated Model WA-NG telescope prosthesis (hereafter WA-NG telescope), an injectable telescope device, in patients with bilateral moderate to profound central vision…
- Trial name
- NCT04468373
- Testing
- WA-NG (NG-IMT) Telescope Prothesis
- Where
- 2 sites in Ireland, Spain
- Volunteers
- 9 people
- Sponsor
- VisionCare, Inc.
Retinitis Pigmentosa, Choroideremia
Study of a Suprachoroidal Retinal Prosthesis
This study is a proof of principal, to evaluate a safety and efficacy of a prototype suprachoroidal retinal implant.
- Trial name
- NCT03406416
- Testing
- 44Ch Bionic Eye Device
- Where
- Australia
- Volunteers
- 4 people
- Sponsor
- Mobius Medical Pty Ltd.
Enucleated; Eye, Evisceration; Traumatic, Eye
Click2Print Artificial Eyes
To undertake a randomised crossover trial in human subjects the Click2Print ocular prosthesis versus an analogue ocular prosthesis demonstrating non-inferiority in the assessment of ocular prosthesis motility, cosmesis, fit and…
- Trial name
- Click2Print (NCT05093348)
- Testing
- Click2Print artificial eye, Hand-made artificial eye
- Where
- United Kingdom
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust
Anophthalmos, Unilateral, Prosthesis User
Subjective Perception of Ocular Prosthesis Wear
The loss of an eye, whether congenital or acquired, is a severe psychological trauma with negative impact on the quality of life of the patient.
- Trial name
- NCT04321382
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Retinitis Pigmentosa
Computer-Assisted Rehabilitation Environment Training After Argus Retinal Prosthesis
The goal of the current project is to fill the unmet clinical needs around the objective assessment of visual function and develop outcome-oriented visual rehabilitation approach using the computer assisted rehabilitation…
- Trial name
- NCT03444961
- Testing
- CAREN system training
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- The Cleveland Clinic
Age Related Macular Degeneration
Study of WA-NG Telescope Prosthesis in Patients With End-stage Age-related Macular Degeneration
This is a pilot study to evaluate the safety of the Model WA-NG telescope prosthesis in patients with bilateral moderate to profound central vision impairment due to end-stage age-related macular degeneration.
- Trial name
- NCT01361256
- Testing
- Telescope prosthesis, WA-NG Telescope Prothesis
- Where
- Israel
- Sponsor
- VisionCare, Inc.
Dry Age-related Macular Degeneration
Feasibility Study of Compensation for Blindness With the PRIMA System in Patients With Dry Age Related Macular Degeneration
In this study, the principle functionality of the device will be tested in humans for the first time. The study will evaluate the extent to which patients with atrophic dry age related macular degeneration (AMD) have evoked light…
- Trial name
- PRIMA FS (NCT03333954)
- Testing
- PRIMA Bionic Vision System
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Science Corporation
Retinitis Pigmentosa
Object Finder for a Retinal Prosthesis
The proposed project seeks to provide object recognition as a feature in a retinal implant system. Participants will be able to direct an object recognition application to find a desired object in the field of view of the…
- Trial name
- NCT04319809
- Testing
- Object recognition subsystem
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Minnesota HealthSolutions
Retinitis Pigmentosa, Choroideremia
Pilot Study of a Suprachoroidal Retinal Prosthesis
This study will be an initial proof of concept study, to evaluate safety and efficacy of a prototype suprachoroidal retinal implant
- Trial name
- NCT01603576
- Testing
- Prototype wide view suprachoroidal retinal prosthesis
- Where
- 2 sites in Australia
- Volunteers
- 3 people
- Sponsor
- Center for Eye Research Australia
Blindness, Acquired
Early Feasibility Study of the Orion Visual Cortical Prosthesis System
This is an early feasibility study of a new device, the Orion Visual Cortical Prosthesis System. The device is intended to stimulate the surface of the visual cortex to induce visual perception in blind individuals.
- Trial name
- NCT03344848
- Testing
- Orion Visual Cortical Prosthesis System
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Second Sight Medical Products
Retinitis Pigmentosa
Argus II Retinal Prosthesis System - Better Vision RP Study
The study is conducted to evaluate the safety and benefit of the Argus II System in a selected patient population with advanced Retinitis Pigmentosa who have a measurable central residual visual field smaller than or equal to 5…
- Trial name
- NCT03418116
- Testing
- Argus II Retinal Prosthesis
- Where
- 3 sites in Germany
- Sponsor
- Second Sight Medical Products
Healthy
Local Tolerability and Safety of Povidone K25 Eye Drops (Artificial Tears Containing Povidone) Versus Placebo in Healthy Volunteers
Instillation of artificial tears is standard treatment in dry eye syndrome and in patients experiencing dry eye symptoms when wearing contact lenses.
- Trial name
- NCT00135824
- Testing
- Povidone K25 eye drops (povidone)
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Novartis
Retinal Degeneration, Inherited Retinal Dystrophy Primarily Involving Sensory Retina
Impact on Daily Life of Patients Using the Subretinal Implant RETINA IMPLANT Alpha AMS
This study aims to assess the impact of the subretinal implant RETINA IMPLANT Alpha AMS on the patient's daily life, using validated activities of daily living and questionnaires.
- Trial name
- NCT03561922
- Testing
- RETINA IMPLANT Alpha AMS
- Where
- 2 sites in France
- Volunteers
- 2 people
- Sponsor
- Retina Implant AG
Retinitis Pigmentosa, Retinal Degeneration
NR600 System Retinal Prosthesis for Patients With Retinal Degenerative Diseases
The study objective is to demonstrate safety of the NR 600 System, and to evaluate the performance of the device in restoring visual activity of daily living in subjects with retinal degenerative diseases and severe visual…
- Trial name
- NR (NCT04295304)
- Testing
- Retinal surgery with implantation of epi-retinal device
- Where
- 6 sites in Belgium, Israel and 1 more
- Volunteers
- 9 people
- Sponsor
- Nano Retina