Clinical trials: Ocular Refraction, open to volunteers
Refractive Errors
Clinical Validation Study Protocol for SmartEyes Smart Optometry Measurement Device (Medical Device Clinical Validation Study)
This study aims to evaluate the SmartEyes smart refraction measurement device in two phases under real outpatient optometry room visits at Wuhan Children's Hospital.
- Trial name
- CVSP-SOMD (NCT07803094)
- Testing
- SmartEyes smart refraction measuring device, Topcon KR800, Subjective refraction
- Volunteers
- 200 people
- Sponsor
- The Hong Kong Polytechnic University
Hyperopic Astigmatism
Effect of WRAD Lens on Axial Growth and Refraction in Low-hyperopic Chinese Children
Myopia is one of the most common visual impairments worldwide.This not only poses long-term risks to individual health but also imposes significant medical and economic burdens on society.
- Trial name
- NCT07682974
- Testing
- With-the-Rule Astigmatic Defocus Lens, With-the-Rule Astigmatic Defocus Lens (Non-plano), Single Vision
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- He Eye Hospital
Cataract (Post-operative Cataract Surgery Follow-up), Refraction Error
Can Tailored Surgical Incisions Reduce Refractive Error and Dependence on Glasses After Cataract Surgery?
Astigmatism is a common cause of continued dependence on glasses after cataract surgery and may lead to patient dissatisfaction with surgical outcomes.
- Trial name
- AST-2 (NCT07623317)
- Testing
- Adapted clear corneal incisions
- Volunteers
- 100 people
- Sponsor
- Linkoeping University
Myopia, Child Myopia Progression
Effect of MiYOSMART iQ Spectacle Lenses on Myopia Progression in Children
This prospective, single-center study aims to evaluate the efficacy and safety of MiYOSMART iQ spectacle lenses with DIMS (Defocus Incorporated Multiple Segments) and Triple Enhanced Design (TED) technology in slowing myopia…
- Trial name
- NCT07387159
- Testing
- MiYOSMART iQ spectacle lenses
- Where
- Russia
- Volunteers
- 70 people
- Sponsor
- Hoya Lens Rus LLC
Refractive Errors, Cycloplegic Refraction
ML Models Predicting Cycloplegic Refractive Error Based on Non-Cycloplegic Parameters in Myopic Adults
This study presents a machine learning model that predicts cycloplegic refraction in adults with myopia using standard non-cycloplegic eye measurements, aiming to reduce the need for cycloplegic drops while still identifying…
- Conditions
- Refractive Errors, Cycloplegic Refraction, Accommodation
- Trial name
- NCT07690813
- Testing
- Machine learning model for predicting cycloplegic refraction
- Where
- China
- Volunteers
- 2,500 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Refractive Errors, Myopia
Correlation Between Preoperative Refraction and Anterior Segment Parameters With ICL Vault
This prospective non-comparative interventional study aims to analyse the pre-operative factors affecting the range of optimal ICL vaulting.
- Conditions
- Refractive Errors, Myopia, Myopic Astigmatism
- Trial name
- NCT05670626
- Testing
- Refractive Surgery
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Refractive Errors
Evaluation of the Agreement Between Automated Program-Operated Phoropter Subjective Refraction and Optometrist-Performed Subjective Refraction
This study aims to evaluate the performance of an automated subjective refraction system that operates a digital phoropter. By comparing its results with those obtained through conventional subjective refraction performed by an…
- Trial name
- NCT07891897
- Testing
- Automated Program-Controlled Subjective Refraction, Optometrist-Performed Subjective Refraction
- Volunteers
- 508 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Refraction Error, Photorefractive Keratectomy
Comparison of Ketorolac Tromethamine 0.5%-Soaked Bandage Contact Lenses Versus Non-Medicated Bandage Contact Lenses on Postoperative Pain Control After Photorefractive Keratectomy
Photorefractive keratectomy (PRK) is a well-established surface ablation procedure for the correction of refractive errors. Despite excellent visual and refractive outcomes, postoperative pain remains a significant concern…
- Trial name
- NCT07705763
- Testing
- Ketorolac Tromethamine 0.5%-Soaked Bandage Contact Lenses, Contact Bandage Lenses
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Madina Teaching Hospital Faisalabad
Ophthalmic Diseases (Specific Types Not Restricted), Cataract
Research on a New Intelligent Mobile Screening and Diagnosis Pattern for Ocular Diseases
The global distribution of primary ophthalmic medical resources is uneven, and the traditional eye disease screening model has problems such as low efficiency, high cost and limited coverage.
- Conditions
- Ophthalmic Diseases (Specific Types Not Restricted), Cataract, Refraction Error, Diabetic Retinopathy (DR)
- Trial name
- NCT07003165
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Patient Satisfaction, Waiting Times, Patient Pathways, Effect of Lifestyle-related, Clinical and Demographic Parameters on Outcomes
Reducing Waiting Time for Vision Refraction Services
The Out-Patient Departments (OPD) is often the first point of contact for patients seeking healthcare services and involves the coordination of both administrative and clinical processes.
- Trial name
- NCT07416175
- Testing
- VRR service optimization
- Volunteers
- 350 people
- Sponsor
- Seva Canada Society
Refractive Errors
Consistency of an Automated Subjective Refraction Program Between Personnel With Diverse Professional Backgrounds and Senior Optometrists
This study aims to evaluate the performance of automated subjective refraction performed by operators with different professional backgrounds.
- Trial name
- NCT07891884
- Testing
- Nurse-Operated Automated Subjective Refraction, Village Doctor-Operated Automated Subjective Refraction, Lay Personnel-Operated Automated Subjective Refraction
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Pseudophakia, Myopia
Treatment of Residual Refraction Errors 6 Months After Trifocal IOL Implantation With Relex-Smile
Successful treatment of residual refraction 6 months after IOL Implantation with Relex-Smile.
- Conditions
- Pseudophakia, Myopia, Hyperopia
- Trial name
- NCT04712318
- Testing
- Relex Smile, Relex smile with fresh corneal lenticule implantation
- Where
- Kosovo
- Volunteers
- 130 people
- Sponsor
- Eye Hospital Pristina Kosovo
Refractive Surgery
Clinical Application Research of 5-Degree (0.05 D) Precision Optometry in Corneal Refractive Surgery
In recent years, the incidence of myopia has been high globally and is exhibiting a rapid upward trend, with projections estimating it will reach 49.8% by 2050.
- Trial name
- NCT07146828
- Testing
- Binocular Wavefront Optometry Machine (BWFOM, Ai-Zhitong Medical Technology Co., Ltd., Zhejiang, China)
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Affiliated Hospital of Nantong University
Pseudophakia, Myopia
Treatment of Residual Myopic Refraction After 6 Months on Pseudophakic Patients Using Relex-Smile
The aim of this study is to assess visual and refractive outcomes after laser vision correction (LVC) - ReLex Smile to correct residual myopic refraction after 6 months of pseudophakic (IOL) implantation.
- Trial name
- Relex-Smile (NCT04693663)
- Testing
- Relex-Smile surgery
- Where
- Kosovo
- Volunteers
- 20 people
- Sponsor
- Eye Hospital Pristina Kosovo
Anisometropia, Myopia
Targeted Lens Intervention for Myopic Anisometropia in Children
The goal of this clinical trial is to learn if our research spectacles will lower the difference in prescription (spectacles degree) between the eyes in children between 6 to 13 years old with anisometropic myopia.
- Trial name
- NCT07533149
- Testing
- More myopic eye: MCL1; Less myopic eye: MCL2
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- Essilor International
Children Aged 3-5 Years, Vision Screening
Shared Reading for Pediatric Ophthalmic Education
We use generative AI to make personalized books for young children about going to the eye doctor. We want to see if reading these stories helps kids feel more comfortable and improves their overall experience at the clinic.
- Conditions
- Children Aged 3-5 Years, Vision Screening, Cycloplegic Refraction
- Trial name
- NCT07590791
- Testing
- Generative AI-customized educational book, standard printed educational leaflet, Commercially available children's book
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Refractive Errors
Cognitive Level Enhancement Through Vision Exams and Refraction
The investigators aim to conduct a mixed-method study in which a randomised controlled trial (RCT) and a descriptive qualitative study will be conducted.
- Trial name
- CLEVER (NCT05458323)
- Testing
- Free near and Distance Vision glasses
- Where
- India
- Volunteers
- 820 people
- Sponsor
- Queen's University, Belfast
Autoimmune Diseases, Inflammatory Diseases
Prospective Observational Study Evaluating the Safety and Efficacy of Immunomodulatory Therapies in Refractory Inflammatory and Autoimmune Diseases
Inflammatory and/or autoimmune diseases represent a very broad group of diseases with highly variable clinical features, including - but not limited to - systemic connectivites and vasculitides.
- Trial name
- ARIES (NCT06757426)
- Where
- 17 sites in France
- Volunteers
- 80 people
- Sponsor
- Groupe français d'étude des Maladies Inflammatoires de loeil
Intraocular Lens Implantation, Cataract
Intraoperative Aberrometry vs Conventional Intraocular Lens Calculation, a Prospective Study.
the goal of this intervention study is to compare prospectively the accuracy of the power calculation between both groups, the intraoperative aberrometry (ORA) vs barrett universal II preoperative calculation (control group) .
- Conditions
- Intraocular Lens Implantation, Cataract, Humans, Ocular, Refraction
- Trial name
- ORAVSCTRL (NCT06219252)
- Testing
- Intraoperative aberrometer, Preoperative intraocular lens calculation
- Where
- Mexico
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Refractive Assessment, Refractive Disorders
Algorithm-assisted Subjective Refraction Program Dedicated to Children
Current refraction assessment in children is dependent on the Eye Care Specialist and lacks standardization. Essilor has developed new algorithm assisted subjective refraction software dedicated to children of 6-12 years old and…
- Conditions
- Refractive Assessment, Refractive Disorders, Hyperopia and Myopia, Astigmatism
- Trial name
- NCT07046065
- Testing
- Non-cycloplegic Objective refraction, Non-cycloplegic conventional subjective refraction, Non-cycloplegic subjective refraction (Kids refraction software vA with Vision-R™)
- Where
- Portugal
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Essilor International