Clinical trials: Ocular Refraction
Retinopathy of Prematurity, Myopia
Prematurity and Ophthalmological Changes
Ophthalmological differences in school-aged children with and without a history of retinopathy of prematurity
- Trial name
- NCT06452524
- Testing
- axial length (AU) and anterior chamber depth (ACD), optical coherence tomography (OCT)
- Where
- Turkey (Türkiye)
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Refractive Error - Myopia Axial, Astigmatism
Refractive Accuracy of "2WIN" and Portable Autorefractors
Youth and some adults have photoscreening refractions and hand-held auto refraction before cycloplegia refraction during new and follow up eye examinations.
- Conditions
- Refractive Error - Myopia Axial, Astigmatism, Accomodation, Visual Impairment
- Trial name
- NCT04249505
- Testing
- "2WIN" Photoscreener, "Plusoptix A12", "Retinomax"
- Where
- United States
- Volunteers
- 708 people, healthy volunteers welcome
- Sponsor
- Alaska Blind Child Discovery
Ocular Refraction
Smart Vision Labs Autorefractor
The study is used to verify the accuracy and repeatability of Smart Vision Labs Refractor.
- Trial name
- NCT02300116
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Smart Vision Labs
Cycloplegic Refraction
Efficacy and Safety of Cyclopentolate Microdrops for Cycloplegic Refraction in Children
The purpose is to test the hypothesis that microdrop instillation of cyclopentolate 1% is non-inferior to standard of care, i.e., standard drop instillation of cyclopentolate 1%.
- Trial name
- NCT06885242
- Testing
- Microdrop instillation of cyclopentolate 1%, Standard drop instillation of cyclopentolate 1%
- Where
- Greece
- Volunteers
- 63 people
- Sponsor
- Aristotle University Of Thessaloniki
Amblyopia
Is Non-cycloplegic Photorefraction Applicable for Screening Refractive Risk Factors of Amblyopia?
Purpose: : This study was performed to compare the accuracy of non-cycloplegic photorefraction with cycloplegic refraction in detection of refractive amblyopia risk factors and determine some corresponding beneficial cut points.
- Trial name
- NCT01308307
- Testing
- photorefraction
- Where
- Iran
- Volunteers
- 185 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Ametropia
Optimization of a Photoretinoscopy Method for Determining the Objective Refraction of Children
The objective is to compare the refractive parameters of the photorefraction prototype device without cycloplegia with the refractive parameters of reference device, an autorefractometer with and without cycloplegia.
- Trial name
- NCT06295536
- Testing
- Comparator device, Closed-field autorefractometer
- Where
- Hong Kong
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia
Comparing Relative Peripheral Refraction on Myopia Progression
The investigators will test our hypothesis that parameters on peripheral defocus can regulate eye growth: For instance, the relative peripheral refraction measured by Multispectral Refraction Topography (MRT) would be significant…
- Trial name
- CMPMRT (NCT06758843)
- Testing
- measure the axial length, visual acuity, and refraction at follow-up of 6- and 12-month
- Where
- China
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Fuzhou Southeast Institute of Visual Ophthalmology
Ametropia
Optimization of a Photoretinoscopy Method for Determining the Objective Refraction of Children With a Smartphone/add-on Device in India
The objective is to compare the refractive parameters of the photorefraction prototype device without cycloplegia with the refractive parameters of reference device, an autorefractometer with and without cycloplegia.
- Trial name
- NCT06524115
- Testing
- Comparator device, Closed-field autorefractometer without cycloplegia, Distance visual acuity check using objective refraction without cycloplegia, Comparator device, Closed-field autorefractometer with cycloplegia
- Where
- India
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Essilor International
Refractive Errors
Correlation Between Refraction and Biometric Parameters
To document the refractive status of Chinese schoolchildren and evaluate the association between the degree of refraction and biometric parameters.
- Trial name
- NCT04346251
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Myopia, Astigmatism
Comparison of Contoura Vision Outcomes Programmed Using the Manifest Refraction Verses Using Phorcides Planning Software in Patients With Oblique Astigmatism
The objective is to compare the percentage of monocular UDVA -0.1 logMAR (20/16) outcomes for each planning strategy (Phorcides and manifest refraction) at the 3-month post operative visit.
- Trial name
- NCT05888337
- Testing
- Contoura LASIK with Phorcides planning strategy, Contoura LASIK with manifest refraction planning strategy
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Bismarck Lasik
Cataract
Intraocular Lens (IOL) Calculation Improvement
Intraocular Lens (IOL) formulas sometimes differ from expected. Using novel measurement methods before and after cataract surgery improved formulas are tried be developed.
- Trial name
- NCT01372657
- Testing
- biometry calculation
- Where
- Switzerland
- Volunteers
- 11 people
- Sponsor
- University Hospital, Basel, Switzerland
Correction of Refraction Error, Attenuation of Bright Light
Contact Lenses With New UV-blocker Manufactured With Different Techniques
This study is a randomized, 4-visit, double-masked, 2x3 bilateral crossover, dispensing trial. The study lenses will be worn as daily wear (DW) for a period of two weeks each with one of the study lenses being worn twice.
- Trial name
- NCT03475875
- Testing
- senofilcon A TEST Lens, senofilcon A CONTROL Lens
- Where
- 5 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataract, Dry Eye
Corneal Sensation and Incidence of Dry Eye Post Refractive Cataract Extraction With FemtoSecond Laser
The study objective is to assess changes in corneal sensation and dry eye signs and symptoms following cataract extraction/femtosecond arcuate relaxing incisions.
- Trial name
- NCT01441895
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ophthalmic Consultants of Long Island
Accommodation
Investigational Study of Accommodation Triggering and Control to Allow for the Performance of Refraction Measurements
An investigational study in the control of the user's accommodative state via visual stimuli.
- Trial name
- NCT03957408
- Testing
- Visual Stimuli
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- EyeQue Corp.
Myopia,, Hyperopia,
Refraction Determination Analysis
Correlating the accuracy of a refraction done over telemedicine to that of a standard refraction, with a study hypothesis that the results will be equivalent.
- Conditions
- Myopia,, Hyperopia,, Astigmatism,, Presbyopia,
- Trial name
- NCT01995435
- Testing
- Telemedicine refraction, Traditional refraction
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Lee, Steven, M.D.
Astigmatism
Hydrophobic Acrylic Toric IOL Designed to Reduce the Effects of Preoperative Corneal Astigmatism
The investigational enVista IOL, Model MX60Tis equipped with toric optics and axis marks on the posterior surface to minimize the possibility of surgically induced astigmatism.
- Trial name
- NCT01852084
- Testing
- enVista® One-Piece Hydrophobic Acrylic Toric IOL, enVista control lens
- Where
- United States
- Volunteers
- 191 people
- Sponsor
- Bausch & Lomb Incorporated
Refractive Error, Myopia
A Comparative Study of Two Daily Disposable Contact Lenses in Higher Myopia Subjects
The purpose of this study is to compare the change from baseline in central corneal curvature at one week, between 2 silicone hydrogel lenses, in higher myopic subjects.
- Trial name
- NCT02066922
- Testing
- Delefilcon A contact lens, Narafilcon A contact lens, Spectacles
- Volunteers
- 19 people
- Sponsor
- Alcon Research
Refractive Assessment, Refractive Disorders
Algorithm-assisted Subjective Refraction Program Dedicated to Children
Current refraction assessment in children is dependent on the Eye Care Specialist and lacks standardization. Essilor has developed new algorithm assisted subjective refraction software dedicated to children of 6-12 years old and…
- Conditions
- Refractive Assessment, Refractive Disorders, Hyperopia and Myopia, Astigmatism
- Trial name
- NCT07046065
- Testing
- Non-cycloplegic Objective refraction, Non-cycloplegic conventional subjective refraction, Non-cycloplegic subjective refraction (Kids refraction software vA with Vision-R™)
- Where
- Portugal
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia, Myopia, Moderate
Software Refraction With Mobilerone Versus Retinoscopy
Software refraction in the mobilerone for myopia and astigmatism is a novel medical device for myopia adults and elder children with or without astigmatism.
- Conditions
- Myopia, Myopia, Moderate, Astigmatism
- Trial name
- SRMR (NCT06059521)
- Testing
- Software refraction with Eye Test Technology in a mobilerone, Retinoscopy
- Where
- 3 sites in China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Beijing Airdoc Technology Co., Ltd.
Refractive Errors, Cycloplegic Refraction
ML Models Predicting Cycloplegic Refractive Error Based on Non-Cycloplegic Parameters in Myopic Adults
This study presents a machine learning model that predicts cycloplegic refraction in adults with myopia using standard non-cycloplegic eye measurements, aiming to reduce the need for cycloplegic drops while still identifying…
- Conditions
- Refractive Errors, Cycloplegic Refraction, Accommodation
- Trial name
- NCT07690813
- Testing
- Machine learning model for predicting cycloplegic refraction
- Where
- China
- Volunteers
- 2,500 people
- Sponsor
- Second Affiliated Hospital of Nanchang University