Clinical trials: Ocular Surface Microbiome
Dry Eyes
Ocular Surface Dry Eye Microbiome
The investigators seek to characterize the identity of all microorganisms residing on the eye's surface (conjunctiva) in healthy eyes and those with dry eye syndrome, using a combination of analyses.
- Trial name
- NCT02306668
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Washington
Allergic Conjunctivitis
The Role of Vitamin D in Corneal Epithelial Barrier Function, Ocular Microbiome, Ocular Inflammation, and Visual Acuity of Children With Allergic Conjunctivitis
A double-blind study to evaluate the role of vitamin D in corneal epithelial barrier function, ocular microbiome, ocular inflammation, and visual acuity of children with allergic conjunctivitis.
- Trial name
- NCT05839938
- Testing
- Vitamin D
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Dry Eye
Ocular Surface Microbiome in Dry Eye Patients
The ocular surface is the first line of defence of the eye, it is therefore where external threats are sensed, and potential insults neutralised.
- Trial name
- NCT02161341
- Where
- Singapore
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Graves' Orbitopathy, Thyroid Eye Disease, TED
Early Risk Stratification of Thyroid Eye Disease in Newly Diagnosed Graves' Disease
The aim of this observational study is to investigate why some people with newly diagnosed Graves' disease (GD) develop thyroid eye disease (TED), also known as Graves' orbitopathy, while others do not.
- Conditions
- Graves' Orbitopathy, Thyroid Eye Disease, TED, Graves' Disease
- Trial name
- SOGO (NCT07812194)
- Testing
- Study-related ophthalmological assessment and biospecimen collection, Blood biomarkers and standardized blood samples including thyroid function status
- Where
- Denmark
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Dry Eye Syndromes
Ocular Surface Microbiome
The purpose of this study is to collect samples from the surface of eyelids to try to grow and identify bacteria or fungus that might be present, and to try to understand why people have dry eye symptoms.
- Trial name
- NCT02298881
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Washington
Ocular Surface Microbiome
Confounding Factors in Ocular Surface Microbiome Research
To elucidate confounding factors in ocular surface microbiome research and to confirm the presence of a core ocular surface microbiome and its temporal stability.
- Trial name
- CoFa (NCT04193917)
- Testing
- Conjunctival swab
- Where
- Belgium
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Microbiota, Ocular Surface
Optimization of Sampling and Processing of Samples for Molecular Microbial Research on Ocular Surface Samples
The use of anesthetics and the processing of the retrieved samples are major confounding factors that influence the results of microbiome research.
- Trial name
- EPSO (NCT04193774)
- Testing
- Conjunctival swab, Oxybuprocaine Hydrochloride 0.4% Eye Drops, artificial tears
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven