Clinical trials: Ocular Surface Tumors
Graft Versus Host Disease in Eye, Ocular Complications
Ocular Complications From Cancer Therapy - Patient Registry and Biobank
The purpose of this study is to collect data on patients seen at University of Maryland after undergoing cancer therapy. Previous medications, ocular history, medical history, clinical evaluations, surgical procedures and…
- Conditions
- Graft Versus Host Disease in Eye, Ocular Complications, Inflammatory Dry Eye Disease
- Trial name
- NCT06874283
- Testing
- Eye exam
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Poly Cystic Ovary Syndrome
The Effect Of Polycystic Ovarian Syndrome Treatment On Ocular Surface.
This is a Descriptive prospective cohort study conducted at the Ophthalmology Department in Kasr-Alaini Hospital. A total of 90 subjects, 30 control females with no relevant medical, gynecological or ophthalmic history, and 60…
- Trial name
- NCT07419776
- Testing
- dry eye diagnostic system of Mediworks, Optical coherence tomography angiography, Contraceptives, Oral, Combined
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Ocular Sebaceous Carcinoma, Ocular Basal Cell Carcinoma
Sentinel Lymph Node Biopsy in Ocular Surface and Adnexal Cancers
The study involves enrollment of patients with sebaceous carcinoma, Merkel's carcinoma, Porocarcinoma, Melanoma, and squamous cell Ca of the ocular surface and adnexa both primary and relapsed after surgical and/or…
- Conditions
- Ocular Sebaceous Carcinoma, Ocular Basal Cell Carcinoma, Ocular Surface Squamous Neoplasia, Merkel Cell Carcinoma, Unspecified
- Trial name
- BLS (NCT05797415)
- Testing
- Sentinel Lymph Node Biopsy
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Breast Neoplasm, Exercise
Oncology Treatment Related Ocular Surface Changes
clinical trial The goal of this clinical trial is to learn if drug trastuzumab works to treat HER2 positive mamma carcinomas without causing dry eye related ocular surface changes in adults.
- Trial name
- 23AA01 (NCT07666724)
- Testing
- Trastuzumab (Herceptin)
- Where
- Hungary
- Volunteers
- 35 people
- Sponsor
- Semmelweis University
Orbital Neoplasms, Conjunctival Neoplasms
Artificial Intelligence-assisted Screening of Malignant Pigmented Tumors on the Ocular Surface
Rare diseases generally refer to diseases whose prevalence rate is lower than 1 / 10 000 and the number of patients is less than 140000.
- Conditions
- Orbital Neoplasms, Conjunctival Neoplasms, Eye Neoplasms
- Trial name
- NCT05645341
- Testing
- screening system for ocular surface malignant tumors
- Where
- China
- Volunteers
- 535 people
- Sponsor
- Sun Yat-sen University
Ocular Surface Squamous Neoplasia, HPV
Feasibility Study of Ocular Surface Squamous Neoplasia Surgical Excision in People Living With HIV in Sub-Saharan Africa
Participants will undergo surgical excision of OSSN at baseline and will be followed at 1 week, 6 weeks, 6 months, and 12 months for post-surgical follow up.
- Trial name
- NCT04704648
- Testing
- Surgical
- Where
- Uganda
- Volunteers
- 84 people
- Sponsor
- AIDS Malignancy Consortium
Scleral Thinning
Evaluation of SclerFIX Graft in Scleral Thinning After Exeresis of Tumors of the Ocular Surface
The purpose of this open, multicenter phase II trial is to confirm the tolerance and evaluate the efficacy of the SclerFIX product, an allograft of umbilical cord lining membrane, in reinforcement of scleral thinning in patients…
- Trial name
- NCT05302609
- Testing
- SclerFIX
- Where
- 2 sites in France
- Volunteers
- 17 people
- Sponsor
- TBF Genie Tissulaire
Pterygium, Dry Eye
Using Impression Cytology to Observe the Cytological Changes of Ocular Surface Cells in Various Ocular Surface Disorders
Currently, due to the advantage of noninvasive, localized, rapid, painless and easily repeatable of impression specimens, the technique is an ideal method of investigating ocular surface disorders when the diagnosis is not…
- Conditions
- Pterygium, Dry Eye, Tumor
- Trial name
- NCT01387971
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Polycystic Ovary Syndrome
Ocular Findings of Polycystic Ovary Syndrome
Purpose: This study aimed to compare the ocular surface disease test results, anterior segment parameters, and ocular response analyzer (ORA) findings of polycystic ovary syndrome (PCOS) patients with those of healthy…
- Trial name
- NCT03896841
- Testing
- Observation
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Advanced/Metastatic NSCLC, Advanced/Metastatic HER2-negative Breast Cancer
A Study Assessing Risk Factors for Oral Mucositis/Stomatitis and Ocular Surface Events in NSCLC and Breast Cancer
This study will identify risk factors for oral mucositis/stomatitis and ocular surface events (OSE) in patients with advanced/metastatic non-small cell lung cancer (NSCLC) and advanced/metastatic human epidermal growth factor…
- Trial name
- NCT06686602
- Testing
- No drug
- Where
- United States
- Volunteers
- 13,759 people
- Sponsor
- Daiichi Sankyo
Performance of the Model
OSPM-Enhanced AI Model to Identify Premalignant and Malignant Ocular Surface Tumors
An OSPM-enhanced deep learning model has been developed for identifying premalignant and malignant tumors using data retrospectively collected from the Ningbo Eye Hospital, Jiangdong Eye Hospital, and the Eye Hospital of Wenzhou…
- Trial name
- NCT06567028
- Testing
- OSPM-Enhanced AI Model
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Ningbo Eye Hospital
Ocular Surface Tumors
Evaluation of Ocular Surface Tumors Using Anterior Segment Optical Coherence Tomography (OCT)
optical coherence tomography (OCT) can scan a range of ocular tissues and take high-resolution image sections during ophthalmic examination..
- Trial name
- NCT06808126
- Volunteers
- 58 people
- Sponsor
- Assiut University