Clinical trials: Odontalgia
Dental Anxiety
Effectiveness of Auricular Acupuncture in Reducing Dental Anxiety and Pain Perception During Orthodontic Extractions Among Adolescents
This prospective, randomised, double-blinded cross-over study aims to compare the effectiveness of auricular acupuncture (AA) with placebo sham acupuncture (PSA) in reducing dental anxiety, pain perception and physiological…
- Trial name
- NCT06434844
- Testing
- Auricular acupunctures
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Pain, Postoperative
Evaluate Analgesic/Sedative Efficacy of Naproxen Sodium and Diphenhydramine in Patients With Postsurgical Dental Pain
The objective of the study is to evaluate the efficacy and safety of a single oral dose of two dose combinations of naproxen sodium and diphenhydramine (DPH) to demonstrate that naproxen sodium/DPH combination provides added…
- Trial name
- Morpheus II (NCT01280591)
- Testing
- Naproxen sodium 440 mg / DPH 50 mg (BAY98-7111), Naproxen sodium 220 mg / DPH 50 mg (BAY98-7111), Naproxen sodium 440 mg (BAYH6689)
- Where
- 2 sites in United States
- Volunteers
- 712 people
- Sponsor
- Bayer
Dental Pain, Postoperative Pain
Comparative Efficacy of 20% Benzocaine Versus TAC Alternate Gel
The project is a study comparing the effectiveness of two topical anesthetics for control of pain associated with dental needle insertion in the palatal mucosa.
- Trial name
- NCT00846690
- Testing
- benzocaine, TAC alternate gel
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Acute Apical Abscess
Valacyclovir Monotherapy in Pain Management of Acute Periapical Abscesses After Emergency Chamber Opening
This study is aimed to evaluate the efficacy of valacyclovir in reducing postoperative pain following emergency chamber opening for acute apical abscess .
- Trial name
- Antiviral (NCT06344195)
- Testing
- Valacyclovir 500 mg, Naproxen Sodium 550mg
- Where
- Pakistan
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Pain, Postoperative
MK0686 in Postsurgery Dental Pain (0686-002)
To compare the pain relieving effect of MK0686 to placebo or ibuprofen after dental surgery.
- Trial name
- NCT00533403
- Testing
- MK0686
- Volunteers
- 114 people
- Sponsor
- Merck Sharp & Dohme LLC
Dental Crowding, Dental Occlusion, Traumatic
Exploration of the Utility of Dental-dedicated MRI for Dentistry
This description observational research is comparative in design, that is comparing existing standard clinical dental images, not obtained in this study, to test (i.e., ddMRI) images.
- Conditions
- Dental Crowding, Dental Occlusion, Traumatic, Endodontic Disease, Orthodontic Treatment
- Trial name
- NCT06948162
- Testing
- dental-dedicated MRI (ddMRI)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Self Medication
AMO CROC Study: Self-medication and Dental Pain of Pulpal and Peri-apical Origin. Qualitative Study
Adult patients with dental anxiety or phobia constitute a population for which access to dental care is difficult and this situation is often associated with am low socio-economic status.
- Trial name
- AMO-CROC (NCT05808452)
- Where
- 2 sites in France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Clermont-Ferrand
Drugs, Investigational
Evaluate Analgesic Efficacy of Fast Release Aspirin
The objective of the study is to evaluate the analgesic efficacy of a single, oral dose of fast release aspirin tablets, 1000 mg (2 x 500 mg) compared to regular aspirin tablets, 1000 mg (2 x 500 mg) and placebo in subjects with…
- Trial name
- TAROT (NCT01117636)
- Testing
- Acetylsalicylic acid (Fast release Aspirin, BAY1019036), Acetylsalicylic Acid (Aspirin, BAYE4465)
- Where
- 2 sites in United States
- Volunteers
- 514 people
- Sponsor
- Bayer
Acute Pain
Analgesic Efficacy and Safety of ADL5859 in Subjects With Acute Dental Pain After Third Molar Extraction
The objective of this study is to evaluate the analgesic efficacy and safety of ADL5859 compared with placebo and an active control (ibuprofen) in subjects with acute dental pain after third molar extraction.
- Trial name
- NCT00993863
- Testing
- ADL5859 30 mg, ADL5859 100 mg, ADL5859 200 mg
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Pain
Study Evaluating the Efficacy of an Ibuprofen Effervescent Tablet in the Treatment of Post-Surgical Dental Pain
Evaluation of the efficacy and safety of a single dose of an ibuprofen effervescent tablet in the treatment of pain following third molar extraction in comparison to single doses of placebo, standard ibuprofen tablets, and…
- Trial name
- NCT00631111
- Testing
- effervescent ibuprofen tablets, effervescent Aspirin plus Vitamin C tablets, ibuprofen tablets
- Where
- United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Toothache, Temporomandibular Joint Disorders
Multimodal Assessment of Sensory Processing and Brain Features in Patients With Chronic Orofacial Pain
This proposal will investigate pain modulatory mechanisms and brain functional and structural characteristics using multiple MRI modalities in persistent dentoalveolar pain disorder (PDAP) patients with and without…
- Trial name
- NCT02630771
- Testing
- Pressure pain threshold
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Dental Pain
Methodological Validation of Ibuprofen Verses Placebo for Post Operative Pain After Third Molar Extraction Surgery
This is a single center placebo controlled, prospective, randomized study on healthy adults undergoing third molar surgery.
- Trial name
- NCT02096926
- Testing
- Ibuprofen
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lotus Clinical Research, LLC
Dental Pain
Evaluation of the Efficacy and Safety of Diclofenac HPBCD 75mg/ml in Treatment of Pain Following Dental Surgery
The present study is aimed at demonstrating the therapeutic equivalence of diclofenac HPBCD 75mg/1ml s.c. with the marketed reference product, Voltarol® 75mg/3ml i.m.
- Trial name
- NCT00943098
- Testing
- Diclofenac HPBCD s.c. 75mg/ml, Voltarol 75mg/3ml i.m.
- Where
- 3 sites in United Kingdom
- Volunteers
- 142 people
- Sponsor
- IBSA Institut Biochimique SA
Injection Pain, Local Anesthesia Infiltration
Sweet-Tasting Solution Versus Placebo to Reduce Pain During Local Anesthetic Injection in Children
The goal of this clinical trial is to learn whether applying a sugar-free flavored sweet solution (SFSS) before local anesthesia helps reduce injection pain in children.
- Conditions
- Injection Pain, Local Anesthesia Infiltration, Pain, Injection Pain Prevention
- Trial name
- NCT07279285
- Testing
- Sugar-free-flavored sweet tasting solution
- Where
- Jordan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Dental Pain
Anesthetic Effectiveness of Lidocaine Versus Articaine in Dentistry
Context: Lidocaine and articaine are two of the most commonly used local anesthetics in dentistry. Lidocaine has often been the anesthetic of choice in clinical practice, but in clinical experience, articaine has proven to be…
- Trial name
- NCT07231614
- Testing
- lidocaine + epinephrine 1:100,000, Articaine 4% with epinephrine 1:100,000
- Where
- Chile
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Austral de Chile
Pain, Postoperative, Dental Pain
A Study of Acetaminophen for Post Surgical Dental Pain
To assess the safety, tolerability, analgesic, efficacy and pharmacokinetics of high dose acetaminophen relative to placebo and low dose acetaminophen relative to placebo over a 24 hour period in patient experiencing moderate to…
- Trial name
- NCT04018612
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Nevakar, Inc.
Dental Pain
Dental Block for Pain Relief in ED Dental Pain Patients
This will be a prospective, observational cohort study assessing immediate pain relief from dental block in ED patients presenting with dental pain. The study will be conducted in the Community Regional Medical Center ED.
- Trial name
- NCT05351099
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- University of California, San Francisco
Dental Pain, Surgery, Dental
Dental Pain (Following Third Molar Tooth Extraction) Study
The purpose of this study is to evaluate the effectiveness of GW406381 (a COX-2 inhibitor) in treating the signs and symptoms of dental pain following third molar tooth extraction.
- Trial name
- NCT00114049
- Testing
- GW406381
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- GlaxoSmithKline
Odontalgia
Oral Quality of Life
The restorative and surgical odontological department at the Nantes University Hospital frequently hosts patients with a severely degraded oral condition who has never benefited from a removable prosthetic rehabilitation.
- Trial name
- NCT03413475
- Testing
- quality of life
- Where
- France
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Dental Anxiety, Dental Pain
Validation of Child Drawing Hospital Scale (CD: H) and the Place of the Drawing in the Evaluation of Dental Anxiety
Objectives: Our study aimed to perform a Turkish validation study of the Child Drawing: Hospital (CD:H) Scale and evaluate the dental anxiety and pain experienced during the treatment by drawing.
- Conditions
- Dental Anxiety, Dental Pain, Validation, Child Drawing Hospital Scale
- Trial name
- NCT05236101
- Testing
- survey research
- Where
- Turkey (Türkiye)
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University