Clinical trials: Oedema, Pulmonary
COPD, ILD
Validation and Clinical Utility of the Lung Sliding Index (LSI) for Differentiating Pulmonary Diseases
This upcoming case-control study aims to confirm the Lung Sliding Index (LSI), a new ultrasound score that measures how well the pleura moves, in various lung diseases.
- Conditions
- COPD, ILD, Bronchiectasis, Pneumothorax
- Trial name
- NCT06983366
- Testing
- Lung Ultrasound
- Where
- Egypt
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Assiut University
Respiration Failure, Cardio Vascular Disease
COMPARE-VENT Feasibility Pilot Study
Cardiac disease complicated by respiratory insufficiency comprises the most frequent indication for cardiac intensive care unit (CICU) admission, with nearly one-third patients requiring advanced respiratory support and over 20%…
- Conditions
- Respiration Failure, Cardio Vascular Disease, Cardiogenic Pulmonary Oedema, Critical Illness
- Trial name
- NCT07656259
- Testing
- Volume Controlled Mode, Pressure Controlled Mode
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Mayo Clinic
Acute Respiratory Distress Syndrome, COVID-19 Acute Respiratory Distress Syndrome
A Randomized Study to Investigate the Effect of Intravenous Imatinib on the Amount of Oxygen in the Lungs and Blood of Adults With COVID-19 Needing Mechanical Ventilation and Supportive Care.
The COVID-19 pandemic has led to an increase in the number of patients admitted to intensive care units (ICU) with acute respiratory distress syndrome (ARDS).
- Conditions
- Acute Respiratory Distress Syndrome, COVID-19 Acute Respiratory Distress Syndrome, Covid19, ARDS
- Trial name
- IMPRESS COVID (NCT04953052)
- Testing
- Imatinib Mesylate
- Where
- 8 sites in India
- Sponsor
- Exvastat Ltd.
Detecting the Number of B-lines in Lung Ultrasound and Its Accuracy in Diagnosis of Weaning Induced Pulmonary Oedema
The Role of Lung Ultrasound in The Diagnosis of Weaning -Induced Pulmonary Edema
The aim of the work is to 1. Assess the incidence of weaning induced pulmonary adema(WIPO). 2. Assess the risk factors of WIPO. 3. Evaluate the role of lung ultrasound in detecting WIPO during spontenous breathing trial(SBT). 4.
- Trial name
- NCT04463303
- Testing
- lung ultrasound
- Volunteers
- 50 people
- Sponsor
- Assiut University
Oedema, Pulmonary
A First Time in Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK2798745 in Healthy Subjects and Stable Heart Failure Patients
This study is the first administration of GSK2798745 in humans. This will be a sponsor un-blinded, placebo-controlled study to investigate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of GSK2798745…
- Trial name
- NCT02119260
- Testing
- GSK2798745 solution, GSK2798745 suspension, GSK2798745 capsule
- Where
- 2 sites in United Kingdom
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Cardiogenic Pulmonary Oedema
Non-invasive Ventilation Versus Continuous Positive Airway Pressure in Cardiogenic Pulmonary Edema
The aim of the present study was to demonstrate that an Non-Invasive Ventilation (NIV) performs better than a Continuous Positive Airway Pressure (CPAP) in the management of Cardiogenic Pulmonary Edema (CPE) within an Intensive…
- Trial name
- NCT02977572
- Testing
- Non-Invasive Ventilation, Continuous Positive AirwayPressure CPAP
- Volunteers
- 114 people
- Sponsor
- Hospital General Universitario de Castellón
ARF Secondary to COPD Exacerbation, ARF Secondary to Cardiogenic Acute Pulmonary Oedema
HERMES STUDY: Study on the Feasibility and Efficiency of Noninvasive Positive-Pressure Ventilation (NPPV) in Prehospital Care
The purpose of this study is determine if NPPV can be performed in a pre-hospital setting very early after onset of dyspnea with a similar benefit in need of intubation and mortality as in previous study in hospital context and…
- Trial name
- NCT00375154
- Testing
- Noninvasive Positive-Pressure Ventilation (NPPV)
- Where
- 8 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain