Clinical trials: Offspring, Adult
Autism Spectrum Disorder
Psychometric Studies of the Chinese Versions of the SRS, CAST, and AQ
Autism spectrum disorder (ASD) is a pervasive neurodevelopmental disorder with prominent reciprocal social and communication impairment and restricted repetitive behavior or interest.
- Trial name
- NCT01247662
- Where
- Taiwan
- Volunteers
- 2,460 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Preoxygenation
Physiological Effects of Different Preoxygenation Strategies
The goal of this clinical trial is to evaluate the performance and physiological effects of different preoxygenation devices in healthy adult and pediatric volunteers (children aged 5-12 years).
- Trial name
- PREOXY II (NCT07564050)
- Testing
- Nasal cannula (NC), Non-rebreather mask (NRM), Non-rebreather mask (NRM) plus Nasal cannula (NC)
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Institute of Mountain Emergency Medicine
Autism Spectrum Disorder (ASD), Relative (Related Person)
Developing an Intervention Facilitating the Use of Eye Contact in Adults With Autism
The aim of this study is to develop a methodological intervention for adults with autism that will help them reduce problems arising from eye contact.
- Conditions
- Autism Spectrum Disorder (ASD), Relative (Related Person), Care Giver
- Trial name
- NCT06924008
- Where
- Netherlands
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Metapneumovirus
Evaluation of the Safety and Immunogenicity of a Live Attenuated Human Metapneumovirus Vaccine
People who are infected with human metapneumovirus (HMPV) may develop upper and lower respiratory illnesses. Children are particularly sensitive to HMPV infection.
- Trial name
- NCT01255410
- Testing
- 10^6 PFU rHMPV-Pa vaccine, 10^5 PFU rHMPV-Pa vaccine
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Diphtheria, Tetanus
Study of the Tdap Combined Vaccine (ADACEL™) as a Booster Dose in Healthy Adults and Children in China
The aim of the study is to assess the safety profile of ADACEL vaccine in a small number of participants in China. Primary objective: To describe the safety in terms of occurrence of serious adverse reactions and grade 3 adverse…
- Conditions
- Diphtheria, Tetanus, Pertussis
- Trial name
- NCT01933776
- Testing
- Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine Adsorbed Tdap
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Worsening Chronic Heart Failure, Diabetic Nephropathy
A Study to Learn How Finerenone (BAY94-8862) Moves Into, Through and Out of the Body, How it Affects the Body, and How Safe it is in Adult Participants With Different Degrees of Reduced Liver Function and in Healthy Participants With Similar Age, Weight and Gender Distribution
Researchers are looking for a better way to treat people who have worsening of chronic heart failure, a long-term condition where the heart does not pump blood as well as it should, as well as to treat patients who have diabetic…
- Trial name
- NCT04881994
- Testing
- Finerenone (BAY94-8862)
- Where
- Germany
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Bayer
Virtual Rehabilitation, CP (Cerebral Palsy)
Virtual Rehabilitation Innovations for Motivation
Children and young people with movement difficulties such as Cerebral Palsy (CP) and Acquired Brain Injury (ABI) report that traditional therapies are highly repetitive and labourious.
- Conditions
- Virtual Rehabilitation, CP (Cerebral Palsy), Brain Injuries, Young Adult
- Trial name
- VR4REHAB-MOT (NCT04430673)
- Testing
- Home-School based VR system trial
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Royal Free Hospital NHS Foundation Trust
Hepatitis B
Clinical Trial of Recombinant Hepatitis B Vaccine (Hansenula Polymorpha, 10μg)
The purpose of this study is to evaluate the safety and immunogenicity of the recombinant hepatitis B vaccine (Hansenula polymorpha, 10μg), with an open-labelled design in adults and randomized, double-blinded, and positive…
- Trial name
- NCT04075201
- Testing
- One dose of investigational vaccine, One dose of control vaccine, Three doses of investigational vaccine
- Where
- China
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Sinovac Biotech Co., Ltd
Children, Adult
Effects of Battle Rope Training on ROM and Pain in Children With Post Traumatic Elbow Contractures.
The primary objective of this study is to assess the effectiveness of battle rope training in improving ROM, reducing pain, and enhancing overall elbow function in children with post-traumatic elbow contracture.
- Trial name
- NCT07248475
- Testing
- Battle Rope Training, Stretching and Heat Therapy
- Where
- Pakistan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Burns
Relationship Between Neutrophil Function and Sepsis in Adults and Children With Severe Thermal Injuries
The study aims to validate neutrophil function, immature granulocyte and plasma free DNA levels as predictive diagnostic biomarkers of sepsis in burn patients.
- Trial name
- SIFTI-2 (NCT04693442)
- Testing
- taking of blood, urine and blood samples and objective scar assessment
- Where
- United Kingdom
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
Magnetic Resonance Imaging, Alzheimer's Disease
Posterior Cingulate Function in Persons With Risk Factors for Alzheimer's Disease
The purpose of this study is to use fMRI techniques to explore a certain part of the brain associated with Alzheimer's disease known as the posterior cingulate.
- Conditions
- Magnetic Resonance Imaging, Alzheimer's Disease, Dementia, Adult Children
- Trial name
- PC (NCT00478166)
- Where
- United States
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Autism
Vitamin/Mineral Supplement for Children and Adults With Autism
The investigators hypothesis is that a new, revised formulation of a vitamin/mineral supplement will result in: 1. improvement of nutritional status in some children/adults with autism, and 2.
- Trial name
- NCT01225198
- Testing
- Multi-Vitamin/Mineral Supplement
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Pneumococcal Vaccine Adverse Reaction
Post-marketing Safety Evaluation of Pneumococcal Vaccines Among Children and Elderly Adults.
The purpose of this observational study is to examine the risk of adverse events following vaccination with 10 or 13-valent pneumococcal conjugate vaccine (PCV10 or PCV13) among infants or children age <59 months and 23-valent…
- Trial name
- NCT04551248
- Testing
- 10 or 13-valent pneumococcal conjugate vaccine, 23-valent pneumococcal polysaccharide vaccine, Influenza vaccine
- Where
- South Korea
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Sungkyunkwan University
Pediatric Cancer
Pilot Evaluation of a Healthy Lifestyle Intervention for Adolescent and Young Adult Survivors of Pediatric Cancer
This is a feasibility and acceptability trial to test a newly developed healthy lifestyle intervention for adolescent and young adult survivors of pediatric cancer.
- Trial name
- NCT04839952
- Testing
- Healthy Lifestyles, Education-Only Control
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins All Children's Hospital
Type 1 Diabetes Mellitus, Genetic Predisposition to Disease
Mechanisms of Type 1 Diabetes Endophenotypes
The goal of this observational study consists of performing cluster analysis to decipher underlying disease mechanisms of type 1 diabetes in children and young adults.
- Trial name
- METYDIA (NCT05764850)
- Testing
- Genome sequencing
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Pediatric Clinical Research Platform
Autism Spectrum Disorder
A Study to Evaluate Scales for Repetitive and Restricted Behaviors in Children, Adolescents, and Adults With Autism Spectrum Disorder (ASD)
This is a non-drug study seeking to characterize different scales to measure repetitive and restrictive behaviors in different ASD sub-populations over time. This study will also explore the use of digital biomarkers.
- Trial name
- NCT03611075
- Testing
- No Intervention
- Where
- 18 sites in United States, Canada and 1 more
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Influenza Immunization
Study With Quadrivalent Recombinant Influenza Vaccine (RIV4) in Participants 9 Through 49 Years of Age.
The purpose of this study was to demonstrate the non-inferiority (NI) of the HAI immune response of RIV4 in participants aged 9 to 17 years vs participants aged 18 to 49 years and to describe the immunogenicity and safety profile…
- Trial name
- NCT05513053
- Testing
- Quadrivalent Recombinant influenza vaccine (RIV4) season/2022-2023/NH
- Where
- 35 sites in United States, Czechia and 2 more
- Volunteers
- 1,308 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Pain Management in Adult Females in Child Bearing Period Aging From 20 to 45 Years Who Are Scheduled for Elective Cesarean Section
Intrathecal Dexmedetomidine Versus Transversus Abdominus Plane Block (TAP) for Postoperative Analgesia After Cesarean Section.
Spinal anesthesia is the most commonly used technique for lower abdominal surgeries as it is very economical and easy to administer.
- Trial name
- NCT04969705
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
OSAS, Recurrent Tonsillitis
ASSESMENT OF TONSIL VOLUME WITH ULTRASONOGRAPHY IN BOTH CHILDREN AND ADULTS
The tonsil volume is an important factor in the decision of the tonsillectomy operation. For this reason, it is important to evaluate the tonsil size before the surgery.
- Trial name
- NCT04030156
- Testing
- tonsillectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Influenza, COVID-19
Comparative Immunogenicity of Concomitant vs Sequential mRNA COVID-19 and Influenza Vaccinations
This is a prospective, randomized randomized immunologic study of response to influenza and SARS-CoV-2 vaccination across four of the US Influenza Vaccine Effectiveness (Flu VE) Network study sites.
- Trial name
- NCT06020118
- Testing
- Simultaneous Vaccination (Influenza Vaccine and mRNA COVID booster), Sequential Vaccination (Influenza vaccine then mRNA COVID booster), Sequential Vaccination (mRNA COVID booster then Influenza vaccine)
- Where
- 8 sites in United States
- Volunteers
- 455 people, healthy volunteers welcome
- Sponsor
- Duke University