Clinical trials: Offspring, Adult
Influenza
ADITEC FLU 2 STUDY: Understanding the Genetics Basis for Immune Responses to Flu Vaccines in Children and Adults
Influenza infection is related to significant morbidity and mortality in children. The trivalent inactive vaccine (TIV) has been documented to have poor immunogenicity in children and the live attenuated influenza vaccine (ATIV)…
- Trial name
- NCT02529904
- Testing
- MF59 - ATIV
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Inflammatory Bowel Diseases, Depressive Episode
Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on Health
This study is a large population-based analysis in the United Kingdom (UK) using routine primary care data to investigate the impacts on quality-of-life outcomes and use of healthcare services in people aged 5 - 25 years…
- Conditions
- Inflammatory Bowel Diseases, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorder
- Trial name
- NCT05206734
- Testing
- No specific intervention
- Where
- United Kingdom
- Volunteers
- 19,469 people, healthy volunteers welcome
- Sponsor
- Momentum Data
Parent-Child Relations, Child Maltreatment
Child-Adult Relationship Enhancement in Primary Care (PriCARE) / Criando Niños Con CARIÑO (CARIÑO)
The purpose of this study is evaluate the effectiveness of PriCARE/CARIÑO to reduce child maltreatment, improve parent-child interactions, and reduce harsh/neglectful parenting, parent stress, and child behaviors.
- Trial name
- NCT05233150
- Testing
- PriCARE/CARIÑO
- Where
- 2 sites in United States
- Volunteers
- 1,932 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Autism, Ocular Surface Disease
Ocular Function in Autism Spectrum Disorder
This study will investigate the visual function in individuals with ASD, with a particular focus on the ocular surface condition and visual function assessment.
- Trial name
- NCT04010422
- Testing
- no intervention
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Iodine Deficiency
Estimating Usual Iodine Intake From Spot Urinary Iodine Concentrations
The overall objective of this study is to develop a reliable method to obtain habitual iodine intakes from spot urinary iodine concentration (UIC) and to assess the prevalence of inadequate iodine intake in school-age children…
- Trial name
- ITURN (NCT03602404)
- Where
- 2 sites in Papua New Guinea, Russia
- Volunteers
- 1,592 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Autism Spectrum Disorder
Handwritten Text Production in Adults With Autism
The main objective is to assess the psycholinguistic and graphomotor characteristics of written production in patients with ASD.
- Trial name
- PEMTAA (NCT06304701)
- Testing
- Cognitive and writing tests
- Where
- France
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Niort
Improving the Early Diagnosis of Osteoporosis in Adults and Children Living in the Abay Region of Kazakhstan
Identification and Assessment of Risk Factors for the Development of Osteoporosis in Adults and Children Living in the Abay Region of the Republic of Kazakhstan Using the Method of Dual-energy X-ray Absorptiometry and Clinical and Epidemiological Research
A survey of people to identify risk factors for osteoporosis, which include age, gender, lifestyle, diet, physical activity, the presence or absence of somatic pathology.
- Trial name
- NCT06344598
- Where
- Kazakhstan
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Semey State Medical University
Pneumococcal Infection
A Study Assessing 13-valent Pneumococcal Conjugate Vaccine in Healthy Chinese Subjects
This study will assess the safety and tolerability of a single dose of 13-valent Pneumococcal Conjugate Vaccine for approximately 1 month after vaccination sequentially in healthy Chinese adults aged 18 through 55 years, followed…
- Trial name
- NCT01531322
- Testing
- 13-valent Pneumococcal Conjugate Vaccine
- Where
- 2 sites in China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Pfizer
Allergic Rhinoconjunctivitis
A Survey of Adults and Children With Allergic Rhinoconjunctivitis (MK-7243-021)
This study will gather information on allergic rhinoconjunctivitis from surveys completed by adults and children.
- Trial name
- AIRS (NCT01535118)
- Volunteers
- 2,765 people, healthy volunteers welcome
- Sponsor
- ALK-Abelló A/S
Behavior and Behavior Mechanisms
Impact of Another Person's Presence on Brain and Behavioral Performance
In a recent study, investigators provided the first neuroscientific data on social facilitation. This neuroimaging study, performed in the macaque monkey, shows a marked improvement in performance in a simple task when a congener…
- Trial name
- SOFEE (NCT03453216)
- Testing
- neuropsychological tests
- Where
- France
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Heart Failure
Developing a Non-invasive Cardiac Functional Health Status Measurement Device
This is a single-center, non-randomized study.Enrolled patients will be placed on a tilt table and a stress test will be performed in a total of 4 different positions. Their blood pressure will be measured at each position.
- Trial name
- NCT01877343
- Testing
- CVInsight(TM)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Florida
Atopic Eczema
Narrowband Ultraviolet B Versus Narrowband Ultraviolet B Plus Ultraviolet A1 for Atopic Eczema
Narrowband ultraviolet B phototherapy is the "standard" phototherapy for atopic eczema; ultraviolet A1 is sometimes used but is not a widely available treatment.
- Trial name
- NCT02915146
- Testing
- combined ultraviolet phototherapy (NB-UVB + UVA1) vs. NB-UVB monotherapy
- Where
- United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Dundee
Diphtheria, Tetanus
Sanofi Pasteur's Tdap Combined Vaccine as a Booster Versus Local DT Vaccine in Children or Versus Local Td Vaccine in Adolescents and Adults in China.
The aim of the study is to assess the immunogenicity and safety profile of ADACEL compared to local adsorbed diphtheria and tetanus combined vaccine (local DT or local Td vaccine in participants in China.
- Conditions
- Diphtheria, Tetanus, Pertussis
- Trial name
- NCT01993173
- Testing
- Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine Adsorbed Tdap (ADACEL), DT vaccine (Diphtheria and Tetanus Combined Vaccine, Adsorbed), Td vaccine (Diphtheria and Tetanus Combined Vaccine for Adults and Adolescents, Adsorbed)
- Where
- China
- Volunteers
- 1,440 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Respiratory Syncytial Virus Infections
Evaluating the Safety and Immune Response to a Respiratory Syncytial Virus (RSV) Vaccine in Adults, RSV-Seropositive Children, and RSV-Seronegative Infants and Children
Human respiratory syncytial virus (RSV) is a common cause of upper respiratory tract illnesses as well as more severe lower respiratory illnesses, including bronchiolitis and pneumonia.
- Trial name
- NCT01459198
- Testing
- RSV MEDI ΔM2-2 vaccine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Transitional Care, Mental Disorder in Adolescence
Psychiatry of Transition in a World in Transition
This clinical study evaluates risk and protective factor to develop psychopathology in transitional age youth. 300 patients will be recruited at the age of 17 years old and assessed at baseline and 2 years later.
- Conditions
- Transitional Care, Mental Disorder in Adolescence, Mental Health
- Trial name
- Transition_psy (NCT04333797)
- Testing
- Risk and Protective Factors Assessment
- Where
- 4 sites in Belgium
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Queen Fabiola Children's University Hospital
Human Parainfluenza Virus 2
Safety of a Live Attenuated Human Parainfluenza Virus Type 2 (HPIV2) Vaccine for Adults, Children, and Infants
Human parainfluenza virus type 2 (HPIV2) can result in severe respiratory illness in infants and young children. This study will test the safety of and immune response to an HPIV2 vaccine aimed at infants and children.
- Trial name
- NCT01139437
- Testing
- Standard Dose HPIV2 Vaccine, Low dose HPIV2 vaccine
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Autism
Vitamin/Mineral Supplement for Children and Adults With Autism
The investigators hypothesis is that a new, revised formulation of a vitamin/mineral supplement will result in: 1. improvement of nutritional status in some children/adults with autism, and 2.
- Trial name
- NCT01225198
- Testing
- Multi-Vitamin/Mineral Supplement
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Hand Foot & Mouth Disease
Safety & Immunogenicity of Enterovirus Type 71 Vaccine in Healthy Adults and Children 6-71months
1. Burden: Hand-foot-and-mouth disease (HFMD) characterized by skin rash in extremities, mouth ulcer and fever among <5 years children.Primarily caused by Enterovirus- predominantly human Enterovirus (EV) 71 and Coxsackie virus…
- Trial name
- NCT04467541
- Testing
- Inactivated Enterovirus Type 71 (EV71) Vaccine (Vero Cell)
- Where
- Bangladesh
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Hearing Loss, High-Frequency
Hybrid Cochlear Implants in Severe to Profound Adults, Children, and Adolescents
The purpose of this study is to determine if adults and children with residual low-pitch hearing in the severe hearing loss range can develop improved speech perception by combining their residual acoustic hearing with electrical…
- Trial name
- NCT01975571
- Testing
- Cochlear® Nucleus™ Hybrid L24, Cochlear® Nucleus™ Hybrid S12
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bruce J Gantz
Cerebra-retinal Angiopathy
COL4A1 Gene Related Cerebra-retinal Angiopathy
This prospective multicenter cohort study aims to define the clinical, radiological and mutational spectrum of the disease related to COL4A1 gene.
- Trial name
- COL4A1 (NCT01097564)
- Testing
- COL4A1 genetic testing
- Where
- France
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris