Clinical trials: Old Age; Atrophy
Elderly, Sarcopenia
Human Muscle Gene Expression Profiles in Young and Old Men
To reach the goals of living longer in better medical conditions, many countries reach the same conclusion: new strategies have to be developed to avoid, or at least limit, the effects of age; this requires a better knowledge of…
- Trial name
- CERA (NCT00725166)
- Testing
- Skeletal muscle aging
- Where
- France
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Healthy
The Effect of Aging and Immobilisation on Muscle
The debilitating effects of immobilisation on muscle strength and size in young individuals are well documented. Moreover, sarcopenia has long been recognized as a major cause of muscle strength loss in old age, however, changes…
- Trial name
- NCT00559806
- Testing
- 2 weeks of unilateral immobilisation and 4 weeks of resistance training
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Cognitive Disorders, Muscular Disorders, Atrophic
Dietary Strategy to Tackle Cognitive and Locomotor Abilities in Early Elderly Subjects
Polyphenols, precisely resveratrol, with red wine as the most substantial source, was associated with improvements in cognitive function.
- Trial name
- WinAging (NCT06871384)
- Testing
- Nonalcoholic red wine group (Intervention group), Drinking water group (Control group)
- Where
- 3 sites in Spain
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Sarcopenia, Sarcopenic Obesity
Effects of a Multi-intervention Programme for the Elderly
1. To develop a multiactivity training programme. 2. To explore the effect of this programme on sarcopenia, sarcopenic obesity, cognitive impairment and Parkinson's disease. 3.
- Conditions
- Sarcopenia, Sarcopenic Obesity, Dementia
- Trial name
- NCT05720416
- Testing
- protein supplementation, muscle strength training, usual care
- Where
- Taiwan
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Central Taiwan University of Science and Technology
Ageing
Study to Assess the Effect of Leucine Along With Resistance Exercise on Muscle Strength and Quality of Life in Elders
The purpose of this study is to determine whether a nutritional supplement with an amino acid called leucine along with resistance exercise are effective in the improvement of muscle strength and quality of life in elderly people.
- Trial name
- NCT00929929
- Testing
- L-leucine., Maltodextrin., Exercise program.
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Elderly, Metabolic Syndrome
Metabolic Syndrome and Vitamin D Level in Old People
In 2012, a cross-sectional survey sampling 1,966 community-dwelling old people was conducted. Structurized questionnaires were interviewed face-to-face by well-trained staffs.
- Conditions
- Elderly, Metabolic Syndrome, Vitamin D Deficiency, Ostreocalcin
- Trial name
- NCT03344718
- Where
- Taiwan
- Volunteers
- 549 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Inflammation, Immune System
Design and Development of a Functional Plant-based Beverage to Improve Nutritional Status and Immunity for the Early Elderly People to Get Well-healthy Ageing
In 2018, for the first time, the number of people aged 65 and over exceeded the number of children under the age of 5. A rise in ageing societies is coming, and new efforts are needed to ensure that this increase in life…
- Trial name
- Immugold (NCT07409480)
- Testing
- Functional plant-based beverage, Control Beverage
- Where
- Spain
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Sarcopenia, Frailty Syndrome
Validity of an App to Detect Frailty and Sarcopenia Syndromes in Elderly
Frailty and sarcopenia are two age-related syndromes which can result in adverse health-related events. The combination of both is more predictive of mortality than either condition alone.
- Conditions
- Sarcopenia, Frailty Syndrome, Aging, Aged
- Trial name
- NCT05148351
- Where
- Spain
- Volunteers
- 775 people, healthy volunteers welcome
- Sponsor
- Catholic University of Murcia
Sarcopenia
Sarcopenia Screening in Elderly Individuals
In this study, it is aimed to evaluate parameters such as sarcopenia screening, muscle mass measurement, loss of strength that may develop due to sarcopenia, loss of balance and related fall, decrease in functionality, fragility…
- Trial name
- NCT06012422
- Testing
- evaluation group
- Volunteers
- 843 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Weakness, Muscle, Delirium in Old Age
YOOMI: Effect of Gamified Physical Therapy Exercise Software on Inpatient Mobility
Patients admitted to the hospital often develop functional impairments due to being in bed most of the day. Each day of bedrest leads to significant muscle loss.
- Conditions
- Weakness, Muscle, Delirium in Old Age, Muscle Atrophy or Weakness, Muscle Loss
- Trial name
- YOOMI (NCT05815017)
- Testing
- Yoomi Physical Therapy Software
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Sarcopenia, Sarcopenic Obesity
Effects of Sarcopenia on General Health Status in Elderly: a Population-based Study
This is a observational study, that aimed to determine the prevalence of sarcopenia using European Wording Group on Sarcopenia in Older People (EWGSOP) algorithm in a general elderly population in Algarve region (Portugal).
- Conditions
- Sarcopenia, Sarcopenic Obesity, Frailty
- Trial name
- NCT05918159
- Testing
- Sarcopenia Assessment
- Where
- Portugal
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Universidade do Algarve
Sarcopenia
Dietary Strategies to Promote Muscle Protein Anabolism in the Elderly
Aging is associated with the loss of lean muscle mass, termed sarcopenia. Food intake and in particular the ingestion of protein or amino acids has been shown to be a powerful stimulus to promote net muscle protein anabolism.
- Trial name
- NCT00557388
- Testing
- Protein/Amino Acids, Physical exercise
- Where
- Netherlands
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Sarcopenia in Elderly, Dynapenia
Reduction in Resistance Training Volume and Neuromuscular Adaptations in Older Adults
The goal of this clinical trial is to evaluate how reducing resistance training volume affects neuromuscular adaptations in older adults aged 60 to 70 years.
- Trial name
- NCT07046130
- Testing
- Resistance Training
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Vocal Cord Atrophy
Modeling the Effects of Vocal Cord Atrophy on Airflow and Voice Quality in Elderly Individuals
1. The purpose of this study is to develop a validated computational model for assessing normative change in these patterns in patients with vocal cord atrophy before and after voice therapy. 2.
- Trial name
- NCT03458104
- Testing
- Cone Beam Computed Tomography, Acoustic/Auerodynamic testing, Laryngovideostroboscopy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Duke University
Sarcopenia
Nutritional Intervention for Sarcopenia
Sarcopenia is an age-related poor healthy outcome. nutrition intervention is one , progressive, generalized loss of muscle mass and the decrement in physical activity.
- Trial name
- NCT03891134
- Testing
- Branched Chain Amino Acid
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- Chimei Medical Center
Sarcopenia
A Study of the Telerehabiliation Intervention Effect of the Tai Chi Exercise on Elderly With Sarcopenia
Sarcopenia is an age-related disease characterized by a progressive decrease in skeletal muscle content and loss of muscle function.
- Trial name
- NCT05767710
- Testing
- AI telerehabilitation - Tai Chi, general telerehabilitation - Tai Chi, traditional rehabilitation - Tai Chi
- Where
- China
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Northeast Normal University
Sarcopenia, Atrophy
Leucine Supplementation in Elderly Men
In the present study the investigators aim to determine whether leucine supplementation can augment muscle mass and strength and improve body composition in healthy elderly men
- Conditions
- Sarcopenia, Atrophy, Aging
- Trial name
- NCT00807508
- Testing
- leucine
- Where
- Netherlands
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Sarcopenia, Old Age; Debility
Study of the Validity and Reliability of Two Digital Dynamometers in Older People
It is a cross-sectional, randomized, and single-center study with a duration of 6 months. The study will follow the STROBE guidelines for cross-sectional studies and CONSORT 2024.
- Conditions
- Sarcopenia, Old Age; Debility, Frailty
- Trial name
- SOVARDDIOP (NCT06623019)
- Testing
- Validation and reliability
- Where
- Spain
- Volunteers
- 413 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Old Age; Atrophy
Effects of Suspension Training in Older Adults
Traditionally, tools that use unstable surfaces have been used to increase the difficulty of exercises by stimulating the recruitment of a greater number of motor units. A new method is suspension training.
- Trial name
- NCT05675631
- Testing
- Suspension training, Strength training
- Where
- Spain
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Sarcopenia
Dietary Strategy to Tackle Sarcopenia in Early Elderly Subjects (FOOP-Sarc)
The main objective of the present study is to add knowledge of the potential health effects and mechanism of action by a dietary strategy based on a VOO rich in phenolic compounds (156 mg hydroxytyrosol and tyrosol/kg oil) alone…
- Trial name
- FOOP-Sarc (NCT05485402)
- Testing
- Refined olive oil (38.6 mg hydroxytyrosol and tyrosol/kg oil), Virgin olive oil rich in phenolic compounds (156 mg hydroxytyrosol and tyrosol/kg oil), Maltodextrin
- Where
- Spain
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili