Clinical trials: Old Age; Debility
Old Age; Debility
Impact of a Physical Exercise Program in a Rural Area
With this work we want to assess whether there are differences in the amount of physical activity per week, measured by accelerometry in 3 groups of subjects, where one group (G1) has been carrying out a PA program called…
- Trial name
- NCT06842849
- Testing
- Exercise program
- Where
- Spain
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Old Age; Debility, Vaccine Hesitancy
COVID-19 Vaccination Willingness in Older Adults Based on Self-determination Theory
Introduction: The COVID-19 vaccine is an effective measure for preventing and controlling COVID-19 epidemics, and the World Health Organization lists older adults as a high-priority group for COVID-19 vaccination.
- Conditions
- Old Age; Debility, Vaccine Hesitancy, Vaccine Refusal
- Trial name
- CVWIOABOSDT (NCT06575114)
- Testing
- Self-determination theory-based health education measures
- Where
- China
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Jing-Shan Deng
Cognitive Impairment, Old Age; Debility
Dietary Supplementation and Cognitive Functions in the Elderly
In recent years, globally, there has been a growth in both the size and the proportion of older adults in the world population. The World Health Organization (WHO) has estimated that by 2030, 1 in 6 people will be 60 years of age…
- Trial name
- ESPINS (NCT06352099)
- Testing
- Dietary supplement with micronised diosmin, hesperidin and herbal extracts
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Frailty Syndrome, Respiratory Muscle Weakness
Longitudinal Ultrasound Assessment of Diaphragmatic and Respiratory Muscle Function Following Respiratory Muscle Training in Frail Older Adults
This study aims to evaluate the effects of an 8-week inspiratory muscle training program on diaphragmatic and respiratory muscle function in frail older adults aged 80 years and above.
- Conditions
- Frailty Syndrome, Respiratory Muscle Weakness, Age-Related Frailty, Geriatric Health
- Trial name
- IMT-1 (NCT07258615)
- Testing
- Inspiratory Muscle Training
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Francisco de Vitoria
Social Isolation, Depression
Discharge Functional Status and Rehospitalization in the Elderly
The DC PROMIS Study (also known as the Discharge Patient Reported Outcomes Measurement Information System Study) is a study to see the effect of patients' social, physical and mental function on their health after hospital…
- Conditions
- Social Isolation, Depression, Anxiety, Debility
- Trial name
- DC PROMIS (NCT02041585)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Northwestern University
Frailty, Dementia
HEalthy Aging Team Supported Home-care Services (HEAT-YASAM)
Depending on the YASAM project which was established to home-visit evaluate community-dwelling older adults (80 years of age and over), we aimed to determine the prevalence (prevalence) of geriatric syndromes (dependence…
- Conditions
- Frailty, Dementia, Depression, Malnutrition
- Trial name
- HEAT-YASAM (NCT05993572)
- Testing
- Comprehensive Geriatric Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Gulhane Training and Research Hospital
Spinal Induced Hypotension, Old Age; Debility
Efficacy of Subclavian Vein/Artery Diameter Index in Predicting the Incidence of the Spinal-Induced Hypotension in Geriatric Patients
The hypothesis of the study will be that the subclavian vein/subclavian artery diameter (SCVD/SCAD) index will be a good predictor of spinal-induced hypotension in geriatric patients.
- Trial name
- NCT07286422
- Testing
- Assessment of the SCV & SCA, Assessment of the IVC and aorta
- Where
- Egypt
- Volunteers
- 107 people
- Sponsor
- Tanta University
Sarcopenic Obesity, Muscle Weakness
Mechanisms of Age-Related Muscle Loss
Two independent, but interrelated conditions that have a growing impact on healthy life expectancy and health care costs in developed nations are the age related loss of muscle mass (sarcopenia) and obesity.
- Conditions
- Sarcopenic Obesity, Muscle Weakness, Protein Metabolism Disorder, Physical Activity
- Trial name
- NCT03113279
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Depression, Old Age; Debility
Assessment of Depression Levels in Elderly Patients With an Orthopedic Fracture Compared to Patients After a Stroke.
Depression is common among elderly patients hospitalized due to acute conditions like strokes or osteoporotic fractures. It has significant impacts on quality of life, hospitalization rates, and mortality.
- Conditions
- Depression, Old Age; Debility, Stroke, Fractures, Bone
- Trial name
- NCT06570356
- Testing
- Geriatric Depression Scale - 15
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Shmuel Harofeh Hospital, Geriatric Medical Center
Frailty
Correlation Between Modified Weakness Index and Postoperative Delirium in Elderly Patients
1. To study whether there is a correlation between weakness and postoperative delusions in elderly non-cardiac surgery patients 2. Can the improved debilitating index predict the delusion after non-cardiac surgery 3.
- Trial name
- NCT05189678
- Testing
- No intervention
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Qianfoshan Hospital
Diabetes Mellitus, Type 2, Depression, Anxiety
Interactive Virtual Assistance for Self-Care Management and Mental Health Promotion in Type 2 Diabetes
BACKGROUD: Health technology is an important tool in the aging process, which may improve the health condition and self-esteem of the elderly, in addition to offering new opportunities and challenges.
- Conditions
- Diabetes Mellitus, Type 2, Depression, Anxiety, Mental Health Disorder, Old Age; Debility
- Trial name
- NCT05329376
- Testing
- Smart Speaker Echo Dot, Usual Care
- Where
- Brazil
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Old Age; Debility
Saraiki Translation, Validity & Reliability of the Activities Specific Balance Confidence (ABC) Scale Questionnaire
There is a need for a culturally adapted screening tool to aid health care professionals or clinicians screen for the presence of fall and balance issues associated with injuries in saraiki population.
- Trial name
- NCT05058703
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Carnitine; Muscle, Functional Status
Impact on Functional Status in Older Adults Treated With L-Carnitine
This study evaluates the impact of the treatment with L-Carnitine on the function of adults over 65 years, in conjunction with regular exercise.
- Conditions
- Carnitine; Muscle, Functional Status, Old Age; Debility
- Trial name
- NCT03180424
- Testing
- L Carnitine, Supervised exercise, Exercise at home
- Where
- Uruguay
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital de Clínicas Dr. Manuel Quintela
Stability, Old Age; Debility
The Feasibility of a Dynamic Exercise Intervention. Psychosocial Effects and Process Evaluation of the Experimental Design.
Current balance and stability interventions have been shown to improve balance through targeting balance impairments and retraining effects.
- Conditions
- Stability, Old Age; Debility, Balance; Distorted
- Trial name
- NCT04932408
- Testing
- Evaluation of the feasibility, psychosocial effects, influence and perception of exercise selection an experimental design of exercises performed at the hip and chest region.
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Derby
Muscle Weakness, Critical Illness
Assessing The Effects of Exercise, Protein, and Electric Stimulation On Intensive Care Unit Patients Outcomes
Elderly patients who experience a prolonged ICU stay are at high risk for developing post intensive care unit syndrome (PICS), a serious medical condition manifested by loss of muscle mass, weakness, malnutrition and…
- Conditions
- Muscle Weakness, Critical Illness, Sarcopenia
- Trial name
- ExPrEs (NCT02509520)
- Testing
- MPR and High Protein Supplement (HPRO) and Neuromuscular Electric Stimulation (NMES)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Maryland, Baltimore
Aging, Inspiratory Muscle Weakness
Effect of Inspiratory Muscle Training on Diaphragm Muscle Thickness, Fatty Liver Density and Aerobic Capacity in Elderly Men: A Randomized Controlled Trial
This randomized controlled trial aims to investigate the effects of a 4-week inspiratory muscle training (IMT) program on diaphragm muscle thickness, fatty liver density, functional capacity, and quality of life in elderly men…
- Conditions
- Aging, Inspiratory Muscle Weakness, Fatty Liver, Reduced Functional Capacity
- Trial name
- IMT AND ELDERL (NCT07193082)
- Testing
- Experimental Inspiratory Muscle Training (IMT Group), Control Group: No inspiratory muscle training.
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
Muscle Tightness, Muscle Weakness
Stretching Techniques of Knee Muscles and Their Effect on Joint Range, Suppleness and Muscle Activity in Elderly
The goal of this clinical trial was to compare the effect of two different types of stretching techniques in elderly population. The main questions it aims to answer are: 1.
- Trial name
- NCT05785416
- Testing
- Proprioceptive Neuromuscular Stretching - Contract Relax stretching (PNF-CR), Static Stretching (SS)
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Deepak Malhotra
Aging, Muscle Atrophy or Weakness
C-Protein in Fatigue and Aging
This study is investigating changes to the proteins in skeletal muscle that contribute to reduced muscle size and muscle function that occurs with aging.
- Conditions
- Aging, Muscle Atrophy or Weakness, Sarcopenia in Elderly, Sarcopenia
- Trial name
- NCT05926219
- Testing
- Fatiguing Exercise
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Sarcopenia, Old Age; Debility
Study of the Validity and Reliability of Two Digital Dynamometers in Older People
It is a cross-sectional, randomized, and single-center study with a duration of 6 months. The study will follow the STROBE guidelines for cross-sectional studies and CONSORT 2024.
- Conditions
- Sarcopenia, Old Age; Debility, Frailty
- Trial name
- SOVARDDIOP (NCT06623019)
- Testing
- Validation and reliability
- Where
- Spain
- Volunteers
- 413 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Frailty Syndrome, COVID-19
Implementation of the Integrated Care of Older People App and ICOPE Monitor in Primary Care (ICOPE)
Introduction: The World Health Organization has launched the INSPIRE-ICOPE-CARE program towards healthy aging. It includes "intrinsic capacity", defined as "the composite of all the physical and mental capacities of an…
- Conditions
- Frailty Syndrome, COVID-19, Healthy Aging, Old Age; Debility
- Trial name
- ICOPE (NCT04413877)
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Liege