Clinical trials: Old Age; Debility
Muscle Weakness, ICU-acquired Weakness
Improving Muscle Function in Nutritionally at Risk, Elderly Patients
The investigators propose to conduct a randomized, control trial of β-hydroxy-β-methylbutyrate (HMB) supplementation in elderly patients (≥65 years of age) with acute respiratory failure, who are identified at high risk for…
- Trial name
- NCT03071354
- Testing
- HMB protein supplement (3g), Nutritional Supplement
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
Old Age; Debility
Impact of a Physical Exercise Program in a Rural Area
With this work we want to assess whether there are differences in the amount of physical activity per week, measured by accelerometry in 3 groups of subjects, where one group (G1) has been carrying out a PA program called…
- Trial name
- NCT06842849
- Testing
- Exercise program
- Where
- Spain
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Social Isolation, Depression
Discharge Functional Status and Rehospitalization in the Elderly
The DC PROMIS Study (also known as the Discharge Patient Reported Outcomes Measurement Information System Study) is a study to see the effect of patients' social, physical and mental function on their health after hospital…
- Conditions
- Social Isolation, Depression, Anxiety, Debility
- Trial name
- DC PROMIS (NCT02041585)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Northwestern University
Old Age; Debility, Gastro-Intestinal Disorder
Optimising the Care and Treatment Pathways for Older Patients Facing Major Gastrointestinal Surgery.
The UK population is ageing. Whilst many people remain active and in good health as they get older, getting older is associated with the onset of many common medical conditions, as well as memory and mobility problems.
- Trial name
- OCTAGON (NCT04545125)
- Where
- 2 sites in United Kingdom
- Volunteers
- 120 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Muscle Weakness
Promoting Seniors' Health With Home Care Aides
This study aims to test whether a safe physical activity program with a built-in motivational enhancement component, performed in a seated position, preserves the function and well-being of older home care clients.
- Trial name
- NCT03301116
- Testing
- Healthy Moves for Aging Well (Healthy Moves), Active Mind for Aging Well (Active Mind)
- Where
- United States
- Volunteers
- 157 people
- Sponsor
- University of Illinois at Chicago
Frailty, Dementia
HEalthy Aging Team Supported Home-care Services (HEAT-YASAM)
Depending on the YASAM project which was established to home-visit evaluate community-dwelling older adults (80 years of age and over), we aimed to determine the prevalence (prevalence) of geriatric syndromes (dependence…
- Conditions
- Frailty, Dementia, Depression, Malnutrition
- Trial name
- HEAT-YASAM (NCT05993572)
- Testing
- Comprehensive Geriatric Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Gulhane Training and Research Hospital
Old Age; Debility
Motor Imagery Training in Community Dwelling Elderly
An aging society is known as having at least 7% of its population aged 65 and older, whereas 14% or more known to be an aged nation.
- Trial name
- NCT04919044
- Testing
- Motor Imagery Training
- Where
- Malaysia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universiti Tunku Abdul Rahman
Old Age; Debility
Correlation of Berg Balance Scale, Time up and Go and Dynamic Gait Index Scale in Elderly
This study will find a correlation Between Berg Balance scale, Time up and Go and Dynamic Gait Index Scale in community Dwelling Ambulatory Elderly.
- Trial name
- NCT05122156
- Where
- Pakistan
- Volunteers
- 125 people
- Sponsor
- Riphah International University
Pre-sarcopenia, Old Age; Debility
Effectiveness of Power Training in Older Women With Pre-sarcopenia
This is a randomized, parallel, double-blind clinical trial. The main objective is to compare the efficacy of resistance training based on power training, multimodal exercise with non-specific exercises and a control group on…
- Trial name
- POSARC (NCT05870046)
- Testing
- Power training in women older than 65 years with pre-sarcopenia, Multimodal and nonspecific exercises in women older than 65 years with pre-sarcopenia
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Nutrition, Healthy, Muscle Weakness
A Randomized Control Trial of Hinex Jelly on the Changes in Muscle Quality and Quantity
Taiwan is about to enter a super-aged society in 2025. The health problems of the elderly are getting more and more attention. Among these geriatric issues, sarcopenia is an important issue.
- Conditions
- Nutrition, Healthy, Muscle Weakness, Elderly
- Trial name
- NCT05917353
- Testing
- Hinex Jelly
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Old Age; Debility, Nursing Home
The Effect of Animal Assisted Activity to Elderly
There is a global increase in the elderly population day by day. Biopsychosocial regressions and various health problems are seen in the elderly, and their care and follow-up are mostly carried out in nursing homes.
- Conditions
- Old Age; Debility, Nursing Home, Loss of Interest in Activities, Loneliness
- Trial name
- NCT05724927
- Testing
- Animal assisted activity
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Atlas University
Old Age; Debility, Balance; Distorted
Effects of Early Sleep After Action Observation Therapy on Balance in Elderly
The study aims at investigating the effects of an early sleep window after Action Observation Therapy (AOT) on balance in elderly.
- Trial name
- NCT05393700
- Testing
- Action Observation Therapy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
DLBCL, Old Age; Debility
Dose Dense Chemotherapy in Elderly Patients > 80 Years Old With DLBCL
Multi-center retrospective analysis of patients with DLBCL aged ≥80 years old treated with R-CHOP-14 compared to other regimens.
- Trial name
- NCT06150053
- Where
- Germany
- Volunteers
- 79 people
- Sponsor
- University Hospital, Saarland
Aging, Fall
Hydraulic Resistance and Older Adults
The goal of this quasi-experimental study using a pre and post test design is to learn about the effect of participating in an exercise program with hydraulic exercise equipment on fall risk in the older adult population.
- Conditions
- Aging, Fall, Old Age; Debility, Muscle Weakness
- Trial name
- NCT06353438
- Testing
- Exercise Program
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- College of Staten Island, the City University of New York
Sarcopenia, Gait Disorders in Old Age
A Double-blind, Placebo-controlled, Randomized INTerventional Clinical Trial (SARA-INT)
The main objective of the study is to evaluate the effect of two daily doses of BIO101 versus placebo on mobility function as measured by gait speed using the 400MW test.
- Conditions
- Sarcopenia, Gait Disorders in Old Age, Muscle Weakness
- Trial name
- SARA-INT (NCT03452488)
- Testing
- BIO101
- Where
- 22 sites in United States, Belgium
- Volunteers
- 233 people
- Sponsor
- Biophytis
Hearing Loss, Gait, Unsteady
Exercise to Improve Balance in Older Adults With Hearing Impairment - a Proof-of-concept Study
Hearing impairment is common in older adults, and recent research points to associations between hearing impairment and balance/mobility.
- Conditions
- Hearing Loss, Gait, Unsteady, Balance; Distorted, Old Age; Debility
- Trial name
- NCT04283279
- Testing
- Virtual reality exercise, Vestibular rehabilitation exercise, Control
- Volunteers
- 60 people
- Sponsor
- Western Norway University of Applied Sciences
Cancer, Geriatric
The Effect of Walking on Fatigue After Chemotherapy in Patients 65 and Older
This study will look at the impact of a self-directed walking program on post-chemotherapy survivors experiencing fatigue. It is hypothesized that the walking program will help lessen fatigue.
- Conditions
- Cancer, Geriatric, Fatigue
- Trial name
- S-PACT (NCT02191982)
- Testing
- Walk With Ease
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Sarcopenic Obesity, Muscle Weakness
Mechanisms of Age-Related Muscle Loss
Two independent, but interrelated conditions that have a growing impact on healthy life expectancy and health care costs in developed nations are the age related loss of muscle mass (sarcopenia) and obesity.
- Conditions
- Sarcopenic Obesity, Muscle Weakness, Protein Metabolism Disorder, Physical Activity
- Trial name
- NCT03113279
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Dignity, Old Age; Debility
INNOVATEDIGNITY: Co-designing Digital Health Technologies With Older People in Homecare Settings.
One of the crucial components of successful ageing is to live independently in old age. Yet in UK alone, nearly 300000 older people require assistance with 3 or more essential daily tasks like eating, bathing and mobility which…
- Conditions
- Dignity, Old Age; Debility, Healthy Aging, Digital Technology
- Trial name
- NCT04884711
- Testing
- No Interventions. Participants will be using their everyday digital health technologies., In depth Interviews, Focus Group Discussions
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Brighton
Muscle Weakness, Fall
Improving Muscle Strength, Mass and Physical Function in Older Adults
Falls and fractures are serious and costly events for elderly individuals: they cause functional impairments, increase mortality and contribute to huge healthcare costs for the society.
- Conditions
- Muscle Weakness, Fall, Sarcopenia
- Trial name
- NCT03297632
- Testing
- Functional resistance exercise
- Where
- Sweden
- Volunteers
- 210 people
- Sponsor
- Region Västerbotten