Old Age; DebilityNCT04919044
Motor Imagery Training in Community Dwelling Elderly
A study testing Motor Imagery Training in people with Old Age; Debility, run by Universiti Tunku Abdul Rahman at 1 site in Malaysia.
Trial summary
An aging society is known as having at least 7% of its population aged 65 and older, whereas 14% or more known to be an aged nation. Age has a detrimental effect on the physical performance and the muscle strength, the reduced muscle strength, mass and structure in the elderly are due to aging, disuse and inactivity. Read more about this study
- Who is it for?
- Ages 60 years and olderHealthy volunteers can take part
- Conditions the study is for
- Old Age; Debility
- What is being tested?
- Motor Imagery Training
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- 1 siteMalaysia
- Study dates
- 8 Aug 2021to 10 Feb 2022
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 60 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Both gender
- Aged 60 and above
- Participant who has a mean score of more than 3 in Movement Imagery Questionnaire-3
- Participant who scored 22 and above in MONTREAL COGNITIVE ASSESSMENT (MOCA) VERSION 7.1
Who cannot join
- Individual with neurological impairment or musculoskeletal injury.
- Participants unable to follow the instructions.
- Individuals using any anti-epileptic drugs and/or psychiatric drugs.
Trial locations and contacts
1 site in 1 country.
Malaysia1 site, 1 recruiting
- Recruiting
Universiti Tunku Abdul Rahman
Kajang, Selangor, 43000
Imtiyaz Ali Mir, +60108040342, imtiyaz2204@yahoo.com
Chong Zheng Wei
About this study
Official title: Effect of Motor Imagery Training On Quadriceps Strength In Community Dwelling Elderly
An aging society is known as having at least 7% of its population aged 65 and older, whereas 14% or more known to be an aged nation. Age has a detrimental effect on the physical performance and the muscle strength, the reduced muscle strength, mass and structure in the elderly are due to aging, disuse and inactivity. In the elderly, the reduction of muscle strength is faster than the associated loss of muscle mass. The maximum isometric strength of knee extensors and muscle mass decrease due to aging. The combination of quadriceps and handgrip strength weakness in the elderly is associated with the poorest scores on quality of life, GP contact-time, gait speed, hospitalization and disability in daily living. Quadriceps weakness among elderly is also proved to be a contributing factor to fall among frail nursing home residents. A systematic review and meta-analysis revealed that quadriceps muscle weakness was associated with greater risk of developing knee osteoarthritis during 2.5 to 14 year follow-up in either gender. In overall, aging cause reduce muscle strength, especially quadriceps muscle, can cause many others negative consequences, thus a study of effect motor imagery on quadriceps muscle strength in community-dwelling elderly should be carried out, if this study is proven to effectively, motor imagery technique can be widely utilized on bedridden elderly or elderly who have severe cardiovascular disease who unable to perform physical activity to maintain or improve their muscle strength.
Read the detailed description
The decrease in the number of skeletal muscle and decline in muscle function is the most important factor in influencing the ability to perform physical function independently in the later stage of our life. The reduction of quadriceps strength with advancing age in both gender is proved to be associated with an increased risk of fractures, increased chance of worsening of knee pain, high risk of osteoarthritis. Quadriceps weakness is also proved to be a contributing factor to falls among frail nursing home residents.
Motor imagery had been widely utilized and proved to benefits different population. Motor imagery training makes a better motor performance as proved to be an effective tool in stroke rehabilitation, it is effective and useful when there are severely injured patients. This imagery training has turned into performance enrichment ways and simulation tools which has been widely utilized in sports psychological interventions as well.
Motor imagery can be defined as a dynamic mental state during which the representation of a given motor act or movement is rehearsed in working memory without any overt motor output. Motor imagery can also be defined as utilizing whole senses to reform or form an experience in one's thought. Motor imagery can be performed in different modes which can be classified into visual, tactile, auditory, gustatory, olfactory, and kinesthetic modes. There are lot of studies which have showed that motor imagery task does activate the cortical and subcortical regions of the brain and they overlap in a great extent with task required movement execution. The parts of the brain proved to participate in motor control consists of the premotor cortex (PMC), supplementary motor area (SMA), as well as the primary motor cortex (M1). All these brain areas are nearly related to the basal ganglia and cerebellum, as a result, large feedback loop systems are formed. The aim of this research is to investigate the effect of motor imagery training on quadriceps strength among community-dwelling elderly. The second aim of our study is to compare the gender differences with regards to quadriceps muscle improvement after motor imagery training.
- Conditions
- Old Age; Debility
- Being tested
- Motor Imagery Training
- Medical subject headings
- Frailty
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Motor Imagery TrainingOther
The number of imagined contractions were 34 trials, each trial was 10 seconds with 5seconds rest between each trial and 2 minutes' rest was given after first 17 trials.
| Study group | Role | What they receive |
|---|---|---|
| Motor Imagery | Experimental | The participants were instructed to imagine and visualize to straighten both knees with eyes closed. You have to see and feel only what you would see and feel if you had to perform the action to straighten both of your knees in sitting position. Imagine the movement using the most comfortable way for you, and make sure not to contract your muscles. Receives: Other: Motor Imagery Training |
| Control | No intervention | No intervention provided. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Quadriceps Strength
The participants were in sitting position, hand-held dynamometer was place on the shin of the tibia just above medial and lateral malleolus. Before measuring the quadriceps strength, participant's knees were held in 90-degree flexion and feet not in contact with the floor. The participants were instructed to straighten leg by pushing against hand-held dynamometer. Peak force generated by dynamometer was recorded. The measurement was repeated three times to take an average of 3.
Measured: Change from baseline Quadriceps strength at 4 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Jun 2021
- Study start8 Aug 2021
- Primary completion10 Feb 2022 (estimated)
- Study completion10 Feb 2022 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Old Age; DebilityStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 50 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Universiti Tunku Abdul Rahman
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Imtiyaz Ali Mir, Universiti Tunku Abdul Rahman
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04919044
- Sponsor's protocol ID
- UMFD3026-4
- Status last verified
- Sep 2021
- First submitted
- 2 Jun 2021
- Last updated
- 2 Sep 2021
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 2 Sep 2021. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Motor Imagery Training On Quadriceps Strength In Community Dwelling Elderly
- ClinicalTrials.gov ID
- NCT04919044
- Acronym / sponsor ID
- UMFD3026-4
- Conditions
- Old Age; Debility
- Study type
- Interventional
- Recruitment status
- Unknown status
- Enrolment
- 50 participants (estimated)
- Lead sponsor
- Universiti Tunku Abdul RahmanUniversity, hospital or other
- Study start
- 8 Aug 2021 (actual)
- Primary completion
- 10 Feb 2022 (estimated)
- Study completion
- 10 Feb 2022 (estimated)
- First posted
- 9 Jun 2021 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
An aging society is known as having at least 7% of its population aged 65 and older, whereas 14% or more known to be an aged nation. Age has a detrimental effect on the physical performance and the muscle strength, the reduced muscle strength, mass and structure in the elderly are due to aging, disuse and inactivity. In the elderly, the reduction of muscle strength is faster than the associated loss of muscle mass. The maximum isometric strength of knee extensors and muscle mass decrease due to aging. The combination of quadriceps and handgrip strength weakness in the elderly is associated with the poorest scores on quality of life, GP contact-time, gait speed, hospitalization and disability in daily living. Quadriceps weakness among elderly is also proved to be a contributing factor to fall among frail nursing home residents. A systematic review and meta-analysis revealed that quadriceps muscle weakness was associated with greater risk of developing knee osteoarthritis during 2.5 to 14 year follow-up in either gender. In overall, aging cause reduce muscle strength, especially quadriceps muscle, can cause many others negative consequences, thus a study of effect motor imagery on quadriceps muscle strength in community-dwelling elderly should be carried out, if this study is proven to effectively, motor imagery technique can be widely utilized on bedridden elderly or elderly who have severe cardiovascular disease who unable to perform physical activity to maintain or improve their muscle strength.
Detailed description
The decrease in the number of skeletal muscle and decline in muscle function is the most important factor in influencing the ability to perform physical function independently in the later stage of our life. The reduction of quadriceps strength with advancing age in both gender is proved to be associated with an increased risk of fractures, increased chance of worsening of knee pain, high risk of osteoarthritis. Quadriceps weakness is also proved to be a contributing factor to falls among frail nursing home residents.
Motor imagery had been widely utilized and proved to benefits different population. Motor imagery training makes a better motor performance as proved to be an effective tool in stroke rehabilitation, it is effective and useful when there are severely injured patients. This imagery training has turned into performance enrichment ways and simulation tools which has been widely utilized in sports psychological interventions as well.
Motor imagery can be defined as a dynamic mental state during which the representation of a given motor act or movement is rehearsed in working memory without any overt motor output. Motor imagery can also be defined as utilizing whole senses to reform or form an experience in one's thought. Motor imagery can be performed in different modes which can be classified into visual, tactile, auditory, gustatory, olfactory, and kinesthetic modes. There are lot of studies which have showed that motor imagery task does activate the cortical and subcortical regions of the brain and they overlap in a great extent with task required movement execution. The parts of the brain proved to participate in motor control consists of the premotor cortex (PMC), supplementary motor area (SMA), as well as the primary motor cortex (M1). All these brain areas are nearly related to the basal ganglia and cerebellum, as a result, large feedback loop systems are formed. The aim of this research is to investigate the effect of motor imagery training on quadriceps strength among community-dwelling elderly. The second aim of our study is to compare the gender differences with regards to quadriceps muscle improvement after motor imagery training.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Motor Imagery | Experimental | Other: Motor Imagery TrainingThe participants were instructed to imagine and visualize to straighten both knees with eyes closed. You have to see and feel only what you would see and feel if you had to perform the action to straighten both of your knees in sitting position. Imagine the movement using the most comfortable way for you, and make sure not to contract your muscles. |
| Control | No intervention | –No intervention provided. |
Who may qualify
- Ages
- 60 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Both gender
- Aged 60 and above
- Participant who has a mean score of more than 3 in Movement Imagery Questionnaire-3
- Participant who scored 22 and above in MONTREAL COGNITIVE ASSESSMENT (MOCA) VERSION 7.1
Key exclusion criteria (3 listed)
- Individual with neurological impairment or musculoskeletal injury.
- Participants unable to follow the instructions.
- Individuals using any anti-epileptic drugs and/or psychiatric drugs.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Motor Imagery TrainingThe number of imagined contractions were 34 trials, each trial was 10 seconds with 5seconds rest between each trial and 2 minutes' rest was given after first 17 trials. | Other | Motor Imagery |
Primary outcome
Quadriceps Strength
Time frame: Change from baseline Quadriceps strength at 4 weeks
The participants were in sitting position, hand-held dynamometer was place on the shin of the tibia just above medial and lateral malleolus. Before measuring the quadriceps strength, participant's knees were held in 90-degree flexion and feet not in contact with the floor. The participants were instructed to straighten leg by pushing against hand-held dynamometer. Peak force generated by dynamometer was recorded. The measurement was repeated three times to take an average of 3.
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Sep 2021.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Motor Imagery Training in people with Old Age; Debility, run by Universiti Tunku Abdul Rahman at 1 site in Malaysia.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 2 Sep 2021. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Malaysia. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
Each site lists its own contact: choose the nearest one under Trial locations. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Quadriceps Strength (time frame: Change from baseline Quadriceps strength at 4 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Sep 2021.