Clinical trials: Older
Chronic Low Back Pain (CLBP)
Impairment Based Treatment Versus Modified Functional Restoration Program in Chronic Low Back Pain Patients
The aim of this feasibility study is to evaluate the practicality of conducting a future randomized controlled trial comparing two rehabilitation approaches for older adults with degenerative chronic low back pain…
- Trial name
- FIRM-CLBP (NCT07699419)
- Testing
- Impairment-based trearment, Modified Functional restoration program
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Cairo University
Type 2 Diabetes Mellitus, Obesity
Form of Dairy Products on Satiety, Food Intake and Post-meal Glycaemia in Young and Older Adults
The proposed study is planned to determine the potential role for regular fat dairy products in short-term metabolic control in younger and older adults and the metabolic flexibility in response to food components, which are…
- Trial name
- NCT02491801
- Testing
- Dietary intervention
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Dual Task Exercises in Elderly People
The Effect of Two Different Dual Task Balance Trainings in Older Adults
The aim of our study is to investigate the effect of integrated and consecutive dual-task exercise trainings in elderly people on the balance, fear of falling and gait performance.
- Trial name
- NCT03981692
- Testing
- Consecutive dual task, Integrated dual task
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Marmara University
Red Blood Cell Health, Biological Aging
Effect of Pentadecanoic Acid Supplementation on Red Blood Cell Health and Biological Aging in Healthy Older Adults
This Phase II randomized, double-blind, placebo-controlled, parallel-group study will evaluate the effects of pentadecanoic acid (C15:0) supplementation on red blood cell (RBC) health and predicted biological age in healthy…
- Conditions
- Red Blood Cell Health, Biological Aging, Healthy Aging
- Trial name
- NCT07812792
- Testing
- Pentadecanoic Acid
- Where
- Canada
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- ReCellience15, Inc
Malnutrition Elderly, Sarcopenia in Elderly
A Nutrition Care Model for Frailty Prevention in the Elderly Based on Design Thinking
This international multicenter study project. A physical function screening activity for the elderly will be held in the community centers.
- Conditions
- Malnutrition Elderly, Sarcopenia in Elderly, Frailty Syndrome
- Trial name
- NCT07504419
- Testing
- nutrition education
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Suh-Ching, Yang
Influenza
Evaluation of the Safety and Immunogenicity of a Recombinant Trivalent Nanoparticle Influenza Vaccine With Matrix M-1 Adjuvant (NanoFlu)
This was a Phase 1/2, randomized, observer-blinded, active-controlled trial to assess the Safety and Tolerability of a Recombinant Trivalent Nanoparticle Influenza Vaccine (Tri-NIV) with Matrix M1™ Adjuvant in Healthy Older…
- Trial name
- NCT03293498
- Testing
- NanoFlu, Fluzone HD - Day 0, Fluzone HD - Day 21
- Where
- 3 sites in United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Novavax
Gait Variability; Elders; Fall; Re-education
Effect of Observation Plus Imagination of Gait on Stride Variability in Young and Older Adults
The aim of study is to examine the combined effect of observation and imagination of gait on stride time variability of stride time among in healthy young and older adults.
- Trial name
- OBI (NCT02120144)
- Testing
- Observation & imagination, Reading
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Aging
Energy Expenditure Responses to Acute Exercise in Older Women (Calorie Expenditure and Exercise)
In older, normal-weight women (60-75 yrs, BMI=18-28 kg/m2), an acute bout of higher-intensity (60% of maximum effort) aerobic exercise, in comparison to an isocaloric bout of lower-intensity (45% of maximum effort) exercise…
- Trial name
- CEE (NCT00988299)
- Testing
- exercise
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Emotionality, Anxiety
Impact of Snoezelen Intervention and Reminiscence Therapy on Seniors' Emotionality and Anxiety
The aim of the study is to verify and compare the short-term and long-term effectiveness (retention) of Snoezelen intervention and reminiscence therapy and to analyze the dynamics of changes in the level of emotionality and…
- Trial name
- NCT07374887
- Testing
- Reminiscence therapy, Snoezelen intervention
- Where
- Slovakia
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Matej Bel University
Obesity, Sarcopenia
Biological Effects of Weight Loss In Older, Obese Women
Obesity and sedentary lifestyle are associated with physical impairments and biological changes in older adults. Weight loss combined with exercise may reduce inflammation and may improve physical functioning in older adults who…
- Trial name
- WL+E (NCT01032733)
- Testing
- Lifestyle Counseling, Educational Control
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Florida
Muscle Weakness
Effects of Creatine Supplementation on Muscle Mass and Function Among Older Women Subjected to Resistance Training
To determine, in a double blind trial, the effects of creatine supplementation during 12 weeks on muscle mass and function of community living older women subjected to resistance training.
- Trial name
- NCT02188849
- Testing
- Resistance exercise training, Creatine
- Where
- Chile
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Chile
COVID-19
Study of Monovalent and Bivalent Recombinant Protein Vaccines Against COVID-19 in Adults 18 Years of Age and Older
The purpose of this Phase III study is to assess the efficacy, safety, and immunogenicity of two CoV2 preS dTM-AS03 vaccines (monovalent and bivalent) as part of primary series vaccinations in a multi-stage approach, as well as a…
- Trial name
- VAT00008 (NCT04904549)
- Testing
- SARS-CoV-2 adjuvanted recombinant protein vaccine (monovalent D614) (primary series), SARS-CoV-2 adjuvanted recombinant protein vaccine (bivalent D614 + B.1.351) (primary series), SARS-CoV-2 adjuvanted recombinant protein vaccine (monovalent B.1.351) (booster dose) >= 4 months after last vaccination
- Where
- 86 sites in United States, Colombia and 9 more
- Volunteers
- 23,670 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Neurologic Manifestations, Neurobehavioral Manifestations
Training Cognitive Control Processes in Older Adults
Control processes are classes of brain activity that initiate, coordinate, synchronize, and regulate elemental cognitive functions for the conduct of goal-directed behavior.
- Trial name
- NCT00586638
- Testing
- Video game based training
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Columbia University
Old Age; Atrophy, Aging
High-Speed Resistance Training Program in Independent Older Adults
The aims of the present investigation are: a) to determine the effects of a 16-weeks high-speed resistance training program on health parameters in independent older adults; and b) to verify the durability of the effects after 6…
- Trial name
- NCT05586087
- Testing
- Experimental group
- Where
- Portugal
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of Évora
Mild Cognitive Impairment
Using fMRI-guided TMS to Increase Central Executive Function in Older Adults (MCI_Sub)
This is an administrative supplement to an existing project "Using fMRI-guided TMS to increase central executive function in older adults: NCT02767323" This award allows extending our existing fMRI-TMS paradigm to patients with a…
- Trial name
- MCI_Sub (NCT04176406)
- Testing
- rTMS
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Duke University
Cardiovascular Risk Factors
Cocoa Extract-enriched Meals and Cardiovascular Risk in Older Population
Obesity prevalence in elderly populations has increased in the last years, and the reduction of overweight and obesity is a priority target in populations of all age ranges worldwide.
- Trial name
- NCT01596309
- Testing
- Cocoa extract
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Pneumococcal Infections
Immunogenicity and Safety of 23-valent Pneumococcal Polysaccharide Vaccine
This is a randomized, double-blind, positive-controlled phase Ⅳ clinical trial of 23-valent pneumococcal polysaccharide vaccine manufactured by Sinovac Biotech Co., Ltd.The purpose of this study is to evaluate the immunogenicity…
- Trial name
- NCT05477693
- Testing
- Experimental 23-valent PPV, Control 23-valent PPV
- Where
- China
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Sinovac Biotech Co., Ltd
Physical Activity, eHealth Literacy
Digital Literacy Training and Acceptance of Physical Activity Apps in Older Women
This randomized controlled study examined whether a structured digital literacy training program could improve eHealth literacy, acceptance of physical activity applications, and behavioral intentions among older women.
- Conditions
- Physical Activity, eHealth Literacy, Technology Acceptance
- Trial name
- NCT07515898
- Testing
- Digital Literacy Training Program
- Where
- Lithuania
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Neurocognitive Disorders
Personalized Interventions Via Health Portraits in Mild Behavioral Impairment
The incidence of MBI and the probability of progression to dementia are high. Early detection and intervention have important clinical significance to reduce the occurrence of dementia, delay the progression of dementia and…
- Trial name
- NCT06416514
- Testing
- Personalized intervention
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fujian Provincial Hospital
Core Stability
Effect of Tailored Core Stability Programs in Older Adults
The increase in life expectancy, together with the high levels of physical inactivity in the population over 65 years of age, has generated a significant reduction in the quality of life of elderly people, characterized by the…
- Trial name
- TCS-OA (NCT07315321)
- Testing
- Core stability training
- Where
- Spain
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Universidad Miguel Hernandez de Elche
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