Clinical trials: Older
Aging
What Older Adults and Their Caregivers Need for Making Better Decisions at Home
Most Canadians wish to stay at home in their old age. As older adults stay at home with the support of home and community services, they are often faced with difficult decisions, such as "Who will look after me when I can't look…
- Trial name
- NCT04327830
- Testing
- Decisional needs assessment
- Where
- Canada
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Inflammation, Sarcopenia
The Combined Effects of Resistance Training and Flax Oil Supplementation Upon Inflammation in Older Adults
Loss of muscle mass and functional ability is a major concern for older individuals. Aging is associated with increased inflammation caused by release of hormone-like compounds termed "cytokines" which are involved in muscle…
- Trial name
- NCT00465153
- Testing
- flax oil containing alpha linolenic acid, Resistance exercise training
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Arterial Stiffness, Autonomic Nervous System
Effects of Active Stretching on Cardiovascular Response and Arterial Stiffness in Older Adults With Low Flexibility
A study of the effects of active static stretching exercise in elderly people with poor lower extremity muscle flexibility on autonomic and cardiovascular responses and balance ability.
- Conditions
- Arterial Stiffness, Autonomic Nervous System, Musculoskeletal Diseases, Range of Motion
- Trial name
- stretching (NCT06944886)
- Testing
- Active Static Stretching Exercise Combined with Breathing Exercise (Experimental Group)
- Where
- Thailand
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Phayao
Healthy Older Adults
Mimic-game & Groove: A TeleXercise Intervention to Get Active & Get Healthy
The composite effect of reduced balance, cognition, gait abnormalities/gait disturbances, and physical activity in older adults leads to fear of falling and decreased participation in daily activities, resulting in reduced…
- Trial name
- NCT05134870
- Testing
- Mimic- game and groove- Telerehabilitation
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Healthy Aging, Elderly (People Aged 65 or More)
Sandplay-Act. Older: Structured Sandplay Activity for Older Individuals
This research was planned to determine the effect of structured sandplay activities on positive and negative affect and levels of meaning in life in elderly individuals.
- Trial name
- NCT07735351
- Testing
- Sandplay-Act. Older: Structured Sandplay Activity for Older Individuals, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Older Adult
Community-based Physical Fitness Exercise on the Older Adults' Functional Fitness and Adherence to Physical Activity
Maintaining adequate physical activity (PA) and regularly exercising are very important to promote the good physical and mental health of the elderly.
- Trial name
- NCT05081505
- Testing
- Structural exercise course, Autonomous group class
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Distress, Psychological, Negative Affect
Nature Exposure Through Virtual Reality (NET-VR) in Older Adults
Daily exposure to nature is associated with improved mood and reduced anxiety symptoms in the overall population. Even brief contact with natural environments can lower stress and restore productivity.However, access to natural…
- Conditions
- Distress, Psychological, Negative Affect, Cognitive Functioning, Older Adults
- Trial name
- NET-VR (NCT07443657)
- Testing
- Nature-Based Virtual Reality Intervention, Waiting list
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Immunosenescence, Uninfected Older
Interferon Reference for Older People - REFIPA Study
The diagnosis of respiratory viral infections is mainly based on PCR tests targeting the DNA or RNA of suspected viruses, including SARS-CoV-2, RSV and influenza viruses.
- Trial name
- REFIPA (NCT07239830)
- Testing
- Uninfected older adults
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Influenza (Healthy Volunteers)
Study Describing the Immunogenicity and Safety of Quadrivalent Recombinant Influenza Vaccine (RIV4) Versus a Licensed Quadrivalent-inactivated Influenza Vaccine (IIV4) (Fluarix® Quadrivalent) in Participants 18 Years of Age and Older in South Korea
To describe the immune response induced by quadrivalent recombinant influenza vaccine (RIV4) and Quadrivalent-inactivated Influenza Vaccine (IIV4) in 18-49 and greater than or equal to (>=) 50 years of age participants by…
- Trial name
- NCT05144945
- Testing
- Quadrivalent Recombinant Influenza Vaccine (RIV4), Quadrivalent inactivated influenza vaccine (IIV4)
- Where
- 3 sites in South Korea
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Pneumococcal Infections
Safety and Immunogenicity of V114 in Healthy Adults (V114-019/PNEU-AGE)
The purpose of this study is to 1) evaluate the safety and tolerability of V114 and 2) to compare the immune responses of the 15 serotypes contained in V114 with V114 versus Prevnar 13™.
- Trial name
- PNEU-AGE (NCT03950622)
- Testing
- V114, Prevnar 13®
- Where
- 30 sites in United States, Canada and 3 more
- Volunteers
- 1,205 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Aging, Vaccine Response Impaired
Impact of Metformin on Immunity
To determine whether metformin (MET) can improve the immune response to the pneumococcal conjugate vaccine (PCV-13) in older adults.
- Trial name
- NCT03713801
- Testing
- Metformin
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Pneumococcal Infections
Study Immunogenicity and Safety of 13-valent Pneumococcal Conjugate Vaccine
This study will assess the Immunogenicity and safety of 13-valent Pneumococcal Conjugate Vaccine compared with 23-valent Pneumococcal Polysaccharide Vaccine. All participants should be naïve of Pneumococcal vaccine.
- Trial name
- NCT02079207
- Testing
- NBP606, Prodiax-23
- Volunteers
- 767 people, healthy volunteers welcome
- Sponsor
- SK Chemicals Co., Ltd.
Suicidal Ideation, Depression
Gamified VR Sports for Elderly Suicidal Ideation
Detailed Description: This quasi-experimental study investigates the effectiveness of a gamified sports exercise intervention delivered through virtual reality (VR) to improve mental health and life expectancy in elderly…
- Conditions
- Suicidal Ideation, Depression, Mental Health Issue
- Trial name
- VR-LIFE-SI (NCT06856083)
- Testing
- Gamified Virtual Reality Sports Exercise Program, Traditional Sports Exercise Program for Elderly Individuals with Suicidal Thoughts
- Where
- Iran
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Frailty Syndrome, Sarcopenia
Design and Validation of FEXO: A Playful Exercise Program for Institutionalized Frail Older Adults
This multicenter randomized controlled trial aims to evaluate the effectiveness of a playful multicomponent exercise intervention (FEXO - Fun Exercise for Older Adults) on intrinsic capacity, frailty, and functional health in…
- Trial name
- FEXO-FRAIL (NCT07133581)
- Testing
- FEXO (Fun Exercise for Older Adults)
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cardenal Herrera University
Mobility Limitation
HealthySteps: Exercise for Older Adults With Mobility Limitation
This study will compare three different exercise programs in older adults who report difficulty walking and will determine if the programs improve walking.
- Trial name
- HealthySteps (NCT01740505)
- Testing
- Timing and Coordination, Aerobic Walking, Stretching and Relaxation
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Simon Fraser University
Older Adults
Clinical Effect of Massage Chair on Older Adults
The use of massage chairs is becoming more popular in many countries. According to the previous reports, some manual massages have positive effects on the mood, pain, fatigue, and sleep quality.
- Trial name
- SEAT (NCT03732729)
- Testing
- massage chair
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Eunju Lee
Aging
Ageing as a Mindset: A Counterclockwise Experiment to Rejuvenate Older Adults
Ageing is generally perceived as a biologically-determined process. There is growing literature, however, that discusses the role of psychological factors in the ageing process.
- Trial name
- NCT03552042
- Testing
- Counterclockwise program, Active control group
- Where
- Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Older Persons Interested in Improving Their Brain Health
A Comparison of Two Approaches to Developing Brain Health Programs
This is a research study, designed to test and create new ideas that other people can use. The purpose of this research study is to evaluate two ways of helping people learn to keep their brain healthy.
- Trial name
- NCT04822129
- Testing
- Treatment as Usual, Cogtrastim Model
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Chronic Heart Failure, Diabetes Mellitus
Exploring Acceptance and Outcomes of an Online-based Self-management Support System in Chronic Illness
The aim of the USECARE project is to improve and test SENACA, an ICT-based self-management support system for chronically ill patients and informal caregivers. 60 end-users will be instructed to use SENACA for approx.
- Conditions
- Chronic Heart Failure, Diabetes Mellitus, Chronic Obstructive Pulmonary Disease, Special Orthopaedic Co-Morbidity After Hip/Knee Replacement
- Trial name
- USECARE (NCT02832739)
- Testing
- SENACA - ICT based self-management support system
- Where
- 2 sites in Israel, Norway
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assuta Medical Center
Protein Digestion Kinetics
Real-time Amino Acid Profiling
This study was designed to obtain information about the effect of new combinations of dairy proteins, in small servings with high protein concentrations, on postprandial amino acid kinetics in blood in an older population.
- Trial name
- RAP (NCT03547362)
- Testing
- Casein, Dairy protein blend 1, Whey protein
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- NIZO Food Research
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