Clinical trials: Older
Salt; Excess, Hypertension
Ketone Ester And Salt (KEAS) in Older Adults
Most Americans consume excess dietary salt based on the recommendations set by the American Heart Association and Dietary Guidelines for Americans.
- Conditions
- Salt; Excess, Hypertension, Aging, Inflammation
- Trial name
- KEAS-O (NCT06868719)
- Testing
- No Salt, No β-OHB, High Salt, No β-OHB, High Salt, High β-OHB
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Indiana University
Osteo Arthritis Knee
Power Production in Older Adults With Knee Osteoarthritis
Knee osteoarthritis is an important cause of functional disabilities at old age. Previous research has demonstrated that individuals with knee osteoarthritis have reduced knee-extensor strength in comparison to healthy…
- Trial name
- NCT03680807
- Testing
- Muscle function test
- Where
- Belgium
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Organ Donation, Donor Designation/Registration
Health Promoters and Organ Donation
Older Hispanics (age 50+ years) are disproportionately overrepresented on the transplant waitlist, but underrepresented as deceased donors and transplant recipients.
- Trial name
- PdD (NCT04007419)
- Testing
- Health Promoters and Organ Donation
- Where
- United States
- Volunteers
- 621 people, healthy volunteers welcome
- Sponsor
- Temple University
Healthy
24-Week Water Aerobics Program for Adults and Older Adults at Different Intensity Levels
This goal of this clinical trial is to verify the best way to do water aerobics with adults and older adults. It wants to answer these questions: Is high-intensity water aerobics better than water aerobics performed at moderate…
- Trial name
- NCT06529354
- Testing
- Moderate-intensity Group, High-intensity Group
- Where
- Portugal
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Beira Interior
Quality of Life, Skills, Coping
Quality of Life and Psychological Strengths of Older People
Older adults have psychological strengths that promote psychological well-being and reduce distress (depression or anxiety) and loneliness, enhancing their quality of life (QoL).
- Trial name
- QUALIFRAG (NCT06381037)
- Testing
- "How to improve your strengths and quality of life".
- Where
- Spain
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- CEU San Pablo University
Physical Activity
Supervised Group-based Walking Intervention Among Inactive Older Adults in Saudi Arabia
The purpose of the proposed study is to compare the effects of supervised group-based walking and non-supervised individual-based walking interventions on frailty, cognitive function and quality of life among inactive older…
- Trial name
- NCT05151575
- Testing
- supervised group-based walking and non-supervised individual-based walking interventions
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Nutrition Disorders in Old Age
Attitudes, Knowledge, Self-efficacy, and Behaviors of Nurses in Nutritional Care for Older People
Even if awareness among nurses regarding the importance of nutritional care for older people has increased in recent years, nurses continue to underestimate the necessary approach to prevent malnutrition.
- Trial name
- NUTRICARE (NCT05691595)
- Testing
- Online survey data collection
- Where
- 2 sites in Italy
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- IRCCS Policlinico S. Donato
Obesity, Sarcopenia
Prevalence of Osteosarcopenic Obesity in Older Adults
Osteosarcopenic Obesity (OSO) is a syndrome characterized by the loss of bone and muscle in addition to increase in the fat tissue as a result of aging process.
- Conditions
- Obesity, Sarcopenia, Osteopenia, Osteoporosis
- Trial name
- NCT04288401
- Where
- Turkey (Türkiye)
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Chronic Disease
A Mobile Intervention Merging Yoga and Self-Management Skills
Chronic disease self-management interventions and meditative movement approaches (.e.g., yoga) can independently improve depressive symptoms.
- Trial name
- MYSkillsMobile (NCT04758312)
- Testing
- MY-Skills Mobile
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Vitamin Deficiency, Mineral Deficiency
Role of Centrum® Silver® in Improving Micronutrient Status in Older Men
Older adults are susceptible to vitamin and mineral deficiencies for a variety of reasons and have an increased demand for many of these micronutrients.
- Conditions
- Vitamin Deficiency, Mineral Deficiency, Aging
- Trial name
- NCT03004807
- Testing
- Centrum Silver Mens' Formula, Control
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Oregon State University
Hearing Loss, Deafness
Auditory-Cognitive Training to Optimize Outcomes for Older CI Users
The proposed study will investigate whether an auditory brain training program can improve cochlear implant (CI) outcomes in older post-lingually deafened CI users.
- Trial name
- ARCog (NCT05176561)
- Testing
- Auditory-Cognitive Training, Non-auditory Cognitive Training
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gallaudet University
Human Papillomavirus Infection
APTIMA HPV 16 18/45 Genotype Assay on the TIGRIS DTS System in Women With ASC-US or Negative Pap Test Results
In both the ASC-US Study and Adjunct Study populations, the objectives are to: evaluate the performance characteristics of the AHPV-GT Assay for detecting cervical disease in women with APTIMA HPV Assay positive results and…
- Trial name
- AHPV-GT (NCT01384370)
- Where
- 3 sites in United States
- Volunteers
- 1,260 people, healthy volunteers welcome
- Sponsor
- Gen-Probe, Incorporated
Medical Male Circumcision
An Implementation Science Study Investigating Profiles of Men Interested in MMC
There are both supply and demand gaps in our understanding of how best to implement MMC services. In terms of supply of MMC services, there is a need to better understand what the best way is of efficiently accessing mature…
- Trial name
- Imbizo (NCT02352961)
- Testing
- Exclusive Intervention Strategy
- Where
- South Africa
- Volunteers
- 2,817 people, healthy volunteers welcome
- Sponsor
- The Aurum Institute NPC
Avian Influenza A Virus
Safety and Immunogenicity of the Monovalent Influenza Vaccine A (H5N8) (Inactivated, Fragmented and Adjuvanted) in Adults and Older Adults
This study aims to demonstrate the safety and immunogenicity of two formulations of the monovalent influenza vaccine candidate A (H5N8) (inactivated, fragmented, and adjuvanted with IB160) from the Instituto Butantan in adults…
- Trial name
- NCT06842173
- Testing
- Monovalent Influenza Vaccine A (H5N8) (Inactivated, Fragmented, and Adjuvanted) 7.5 mcg, Monovalent influenza vaccine type A (H5N8) 15 mcg
- Where
- 5 sites in Brazil
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Butantan Institute
Sleep, Gut Microbiome
Impact of Different Types of Higher Dietary Protein Intake on Sleep Quality in Singapore Older Adults
Today, insufficient sleep has become a growing global problem. Sleep is essential to health and changes in sleep patterns are a part of the aging process.
- Conditions
- Sleep, Gut Microbiome, Cardiometabolic Risk
- Trial name
- NCT05400005
- Testing
- Dietary protein
- Where
- Singapore
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Physical Fitness in Older Adults, Exercise Program
"Bliib Fit - Mach Mit!" in Residential Care Facilities
The goal of this clinical trial is to learn, if the video-based exercise program "Bliib fit - mach mit!" can be used to improve physical fitness in older adults living in residential care facilities.
- Trial name
- NCT06738186
- Testing
- Video-based exercise program, Caregiver-led activation program
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Eastern Switzerland University of Applied Sciences
Mild Dehydration
The Effect of Acute Mild Dehydration on Blood Pressure Control
The goal of this project is determine how acute mild dehydration impacts blood pressure control at rest and during static exercise.
- Trial name
- NCT03560869
- Testing
- Normal hydration, Dehydration
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Sarcopenia, Older People
Evaluation of Sarcopenia With SARC-F and Anthropometric Measurement
The aim of this study is to examine the performance of determining the sarcopenia by anthropometric measurements (mid-upper arm circumference and calf circumference) added to the SARC-F questionnaire developed as a screening tool…
- Trial name
- NCT05241886
- Testing
- anthoropometric measurement, SARC- F questionnare
- Where
- Turkey (Türkiye)
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Ege University
Sedentary Behavior, Physical Inactivity
Promoting Physical Activity in Older Hispanic/Latino(a) Adults
In this randomized controlled trial, study staff will randomize 130 Hispanic/Latino adults without dementia and over age 55 from Southern California and from Kaiser Permanente Washington (State) to either the culturally adapted…
- Conditions
- Sedentary Behavior, Physical Inactivity, Alzheimer Disease, Protection Against
- Trial name
- NCT06362824
- Testing
- De Pie Intervention, Active Comparison Group: Healthy Actions And Lifestyles To Avoid Dementia (HALT-AD)
- Where
- 2 sites in United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
COVID-19
Study of GRT-R910 COVID-19 Boost Vaccine in Healthy Volunteers
The primary objective was to assess the safety and tolerability of 2 different doses (10 or 30 µg) of GRT-R910 when administered as a boost in healthy adults previously vaccinated with the AstraZeneca, Janssen/Johnson and…
- Trial name
- NCT05148962
- Testing
- GRT-R910
- Where
- 3 sites in United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Gritstone bio, Inc.
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