Clinical trials: Older Adults With Mild Neurocognitive Disorders
Cognitive Dysfunction, Mild Cognitive Impairment
Effect of Dual Task Exercise on Cognitive and Physical Function in the Elderly With Mild Cognitive Impairment
The purpose of this study is to investigate the effect of the dual task exercise program on cognitive and physical function in the elderly with mild cognitive impairment.
- Trial name
- NCT05855785
- Testing
- dual task exercise, home exercise
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Seoul National University Boramae Hospital
Mild Cognitive Impairment
Immersive Virtual Reality for Dual-task Training in Older Adults With Mild Cognitive Impairment: A Randomized Controlled Trial
Mild cognitive impairment (MCI) is a pre-dementia state marked by a higher risk of conversion to dementia. Presently, strategies to delay the progression of MCI to dementia, such as routine exercise and cognitive activities, are…
- Trial name
- NCT05730790
- Testing
- Cognitive-motor dual task training (DTT), Cognitive single task training (CSTT), Motor single task training (MSTT)
- Where
- Singapore
- Volunteers
- 54 people
- Sponsor
- Tan Tock Seng Hospital
Mild Cognitive Impairment
VR-CogMoBal Training for Reducing Falls Among Older Adults With Mild Cognitive Impairment
Older adults often display gait instability, impaired balance control and cognitive decline that lead to falls and fall risks. Approximately 60% of the elderly people with cognitive deficits experience a detrimental fall each…
- Trial name
- NCT03765398
- Testing
- VR Cognitive-motor-balance training
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Illinois Chicago
Mild Cognitive Impairment (MCI)
Cognitive-motor Training in Community-dwelling Older People With Mild Cognitive Impairment
As the global population ages, the prevalence of mild cognitive impairment (MCI) among older adults, which ranges from 5% to 40%, is expected to rise.
- Trial name
- NCT07241598
- Testing
- Smart±step cognitive-motor training
- Where
- Thailand
- Volunteers
- 70 people
- Sponsor
- Mahidol University
Subclinical Hypothyroidism
Subclinical Hypothyroidism and Mind in the Elderly
Some recommendations of expert consensus on subclinical hypothyroidism (SH) are controversial in those areas with not enough information to reach a conclusion, such as not recommending treatment with thyrotrophic hormone of 4-10…
- Trial name
- NCT00921050
- Testing
- levothyroxine sodium
- Where
- 2 sites in Mexico
- Volunteers
- 70 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Mild Cognitive Impairment, Insomnia
Multicomponent Behavioral Sleep Intervention for Insomnia in Older Adults With Mild Cognitive Impairment
Insomnia symptoms in older adults with mild cognitive impairment represent a significant public health burden in terms of impaired quality of life, risks from untreated insomnia, and risks from pharmaceutical insomnia treatment.
- Trial name
- MBSI-I (NCT04364191)
- Testing
- Multicomponent Behavioral Sleep Intervention for Insomnia, Active Control
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Mild Cognitive Impairment, So Stated, Mild Dementia
Cognitive/Physical Computer-Game Blended Training With Personalized Brain Network Activation Technology for the Elderly
The study involves a novel Virtual Reality Interface that offers full-body immersion "Alterniity AR" and more specifically computer exercises blended with game activities.
- Conditions
- Mild Cognitive Impairment, So Stated, Mild Dementia, Healthy
- Trial name
- AlterniityAR (NCT02417558)
- Testing
- Alterniity Augmented Reality (AAR), VideoGrade
- Volunteers
- 607 people, healthy volunteers welcome
- Sponsor
- XtremeVRI AG
Mild Cognitive Impairment
Memory Training Versus Yogic Meditation Training in Older Adults With Mild Cognitive Impairment
The purpose of this pilot study is to test whether 6 months of supervised weekly Kundalini yoga classes and a brief daily meditation homework assignment can improve memory and thinking in older adults with mild memory complaints…
- Trial name
- NCT01983930
- Testing
- Kundalini yoga and meditation, Memory Training
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- University of California, Los Angeles
Mild Cognitive Impairment (MCI)
Hippocampal Temporal Interference Stimulation for Memory and Dual-Task Postural Control in Older Adults With Mild Cognitive Impairment
This trial aims to investigate whether a single session of 40 Hz hippocampal temporal interference stimulation can improve memory function and dual-task postural control among older adults with mild cognitive impairment (MCI).
- Trial name
- NCT07771036
- Testing
- Temporal Interference Stimulation
- Where
- China
- Volunteers
- 21 people
- Sponsor
- Shanghai University of Sport
Mild Cognitive Impairment
Tai Ji Quan and Cognitive Function in Older Adults With Mild Cognitive Impairment
To determine the efficacy of a cognitively enhanced exercise intervention - Tai Ji Quan: Moving to Maintain Brain Health in improving global cognitive function and dual-task ability in older adults with mild cognitive impairment.
- Trial name
- NCT04070703
- Testing
- The Go for Exercise & Healthy Aging Project
- Where
- United States
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
Subjective Cognitive Decline (SCD), Mild Cognitive Impairment (MCI)
Study of Bedroom Environment Sleep Intervention at Home for Older Adults Living Alone With Memory Concerns
This is an eight-week pilot research study designed to test whether simple changes to the bedroom environment along with brief sleep hygiene strategies, can improve sleep in older adults who live alone, have memory concerns, and…
- Conditions
- Subjective Cognitive Decline (SCD), Mild Cognitive Impairment (MCI), Insomnia
- Trial name
- NCT07440498
- Testing
- Bedroom Environment Tailoring, Sleep Health Education
- Volunteers
- 40 people
- Sponsor
- Johns Hopkins University
Dementia, Neurocognitive Disorders
Effectiveness and Cost-Effectiveness of Robot Therapy With the Paro Robot in People Living With Dementia
The purpose of this study is to evaluate the effectiveness and cost-effectiveness of group robot therapy with the PARO therapy robot in terms of quality of life and neuropsychiatric symptoms in people living with dementia in…
- Conditions
- Dementia, Neurocognitive Disorders, Mild Cognitive Impairment
- Trial name
- NCT05884424
- Testing
- PARO Therapy Robot
- Where
- 15 sites in Spain
- Volunteers
- 123 people
- Sponsor
- Instituto de Mayores y Servicios Sociales (IMSERSO)
Mild Cognitive Impairment
Personalized Medicine in the Elderly With Vision Impairment and Mild Cognitive Impairment
Globally, approximately 55 million people suffer from dementia, and 60-70% of cases are due to Alzheimer's disease (AD). Increasing scientific evidence highlights that the pathological changes underlying AD and other forms of…
- Trial name
- Eye-MCI (NCT06942728)
- Testing
- nLIFE EyeFitness
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Cognitive Dysfunction
Efficacy Study of Yi-Zhi-An-Shen Granules For Older Adults With Amnestic Mild Cognitive Impairment
The main purpose of this study is to investigate the safety and efficacy of Yi-Zhi-An-Shen Granules in participants with amnestic mild cognitive impairment (aMCI).
- Trial name
- NCT03601000
- Testing
- Yi-Zhi-An-Shen
- Where
- 2 sites in China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Mild Cognitive Impairment, Mild Dementia
Effect of High Frequency/Low Intensity Transcranial Magnetic Stimulation in Cognitive Traits of an Elderly Population of Subjects With Mild Cognitive Impairment and Mild Dementia.
There are no pharmacological interventions that delay or prevent the transition of mild cognitive impairment to dementia. Several studies have shown that transcranial magnetic stimulation (TMS) could be useful in increasing…
- Trial name
- NCT03983655
- Testing
- High Frequency Low Intensity TMS
- Where
- Mexico
- Volunteers
- 37 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Mild Cognitive Impairment (MCI), Stress (Psychology)
(MAP) Pilot Randomized Controlled Trial for Older Adults With Mild Cognitive Impairment and Elevated Stress
The purpose of this study is to test whether a tailored mindfulness program, called the Mindful Awareness Practice (MAP) or a Health Education Program (HEP) can reduce stress and improve memory, mood, and well-being in older…
- Trial name
- CohnMAP-RCT (NCT07389655)
- Testing
- Mindful Awareness Practice (MAP)
- Volunteers
- 30 people
- Sponsor
- Rush University Medical Center
HIV/AIDS, Aging
Psychosocial Intervention for Older HIV+ Adults With HAND
CTNPT 029 will test the feasibility and acceptability of cognitive remediation group therapy in older adults living with HIV who have been diagnosed with HIV-associated neurocognitive disorder (HAND).
- Conditions
- HIV/AIDS, Aging, Mild Cognitive Impairment, Group, Peer
- Trial name
- IN-HAND (NCT03483740)
- Testing
- CRGT, HIV group therapy
- Where
- 3 sites in Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Mild Cognitive Impairment, Dementia Prevention
Effectiveness of Non-pharmacological Interventions for Dementia Prevention in Elderly Patients With Mild Cognitive Impairment
The aims of this study is to evaluate the effectiveness of non-pharmacological interventions program in preventing progression from mild cognitive impairment to dementia in patients with mild cognitive impairment in the short…
- Trial name
- NCT06453746
- Testing
- Home-based cognitive training exercises, Supervised cognitive training exercises
- Where
- Vietnam
- Volunteers
- 192 people
- Sponsor
- Gia Dinh People Hospital
Prodromal Alzheimer's Disease, Mild Cognitive Impairment
The Digital Memory Notebook
Compensatory aids (e.g., alarms, calendars) play an important supporting role when completing everyday tasks (e.g., appointments, medication management), and there is a growing body of scientific work suggesting that compensatory…
- Conditions
- Prodromal Alzheimer's Disease, Mild Cognitive Impairment, Subjective Cognitive Complaints
- Trial name
- DMN (NCT04240665)
- Testing
- Digital Memory Notebook (DMN) Application
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Davis
Frailty, Mild Cognitive Impairment
Effects of Square-stepping Exercise on Frailty and Cognitive Function in Elderly With Frailty and MCI
This is a single-blinded, randomized controlled trail with pre- and post-measurements. The inclusion criteria are: (1) age between 65 to 90 years old, (2) the presence of at least one of the 5 physical characteristics defined by…
- Trial name
- NCT04463797
- Testing
- Square-stepping exercise, Stretching and strengthening
- Where
- Taiwan
- Volunteers
- 31 people
- Sponsor
- National Yang Ming Chiao Tung University