Clinical trials: Older People
Sarcopenia
Resistance Exercise or Vibration With HMB for Sarcopenia
Sarcopenia is a geriatric syndrome characterised by the progressive loss of skeletal muscle mass and function with a risk of adverse outcomes. In Hong Kong, the prevalence of sarcopenia in community-dwelling older people was 9%.
- Trial name
- NCT04028206
- Testing
- Hydroxymethylbutyrate, Low-magnitude High Frequency Vibration (LMHFV), Elastic-band Exercise
- Where
- Hong Kong
- Volunteers
- 144 people
- Sponsor
- Chinese University of Hong Kong
Cognitive Impairment
Nurse-Led Active Music Program in Older Adults With Cognitive Impairment
This pilot study evaluated the feasibility and acceptability of a structured, nurse-led active music program for older adults with cognitive impairment living in a long-term care facility.
- Trial name
- NCT07831850
- Testing
- Nurse-Led Active Music Program
- Where
- Spain
- Volunteers
- 11 people
- Sponsor
- Universidad de Almeria
Aging, Cognitive Function Abnormal
Executive Functioning Training Study
Cognitive aging in people with HIV (PWH) is of increasing concern for several reasons: 1) between 52%-59% of PWH experience cognitive impairment known as HIV-Associated Neurocognitive Disorder (HAND) which impacts everyday…
- Conditions
- Aging, Cognitive Function Abnormal, Cognitive Performance, Cognitive Training
- Trial name
- EFT (NCT05598047)
- Testing
- Executive Functioning Training
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Dynapenia, Abdominal Obesity
Effectiveness of Whole Body Vibration on Health Outcomes in Older Adults With Dynapenic Abdominal Obesity
This study focuses on whole body vibration training (WBVT), a form of neuromuscular training that uses mechanical vibrations. WBVT has been shown to improve muscle function, bone mineral density, and quality of life.
- Trial name
- NCT07180485
- Testing
- whole body vibration training, control group
- Volunteers
- 120 people
- Sponsor
- Dalin Tzu Chi General Hospital
Low Back Pain
MY RELIEF- Evidence Based Information to Support People Aged 55+ Years Living and Working With Persistent Low-back Pain.
Low back pain is the main cause of activity limitation and work absence across the world, leading to a high social and economic burden for individuals, families, the labour market and society.
- Trial name
- MY-RELIEF (NCT04673773)
- Testing
- A Massive Open Online Course
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Lund University
Frailty Syndrome
Clinical Intervention in Frail Older People (FRAILCLINIC)
Frailty is the main risk factor for the development of incident disability in older people and one of the most important for other adverse outcomes (death, hospitalisation, falls, and permanent institutionalisation).
- Trial name
- FRAILCLINIC (NCT02643069)
- Testing
- Intervention Geriatric Program
- Where
- Spain
- Volunteers
- 821 people
- Sponsor
- Hospital Universitario Getafe
Diabetes, Older Diabetic Persons Without Dementia
CCT for Older Diabetic Adults
The current study examines the efficiency of a home-based computerized cognitive training (CT) intervention targeting older adults with diabetes.The primary aim of the study is to evaluate the effects of CCT on cognitive and…
- Trial name
- NCT02709629
- Testing
- Individualized and adaptive computerized cognitive training, Active control
- Where
- Israel
- Volunteers
- 85 people
- Sponsor
- Sheba Medical Center
Old Age
Relationships Between Sexuality and Mental Health in Older People
The prevalence of sexual activity decreases with age, particularly among individuals over 60 years old. Although physical dysfunctions, such as erectile disorders, play a role, the decline in sexuality is also linked to cultural…
- Trial name
- PASS (NCT07252583)
- Testing
- questionnaires of quality of life
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Clermont-Ferrand
Frailty, Disability Physical
Viability of an Educational Program for Lifestyle Changes and an Algorithm for the Derivation of Exercise Programs in Older People at Risk of Dependency at Primary Care.
According to the INE in 2021, more than 9 million people are currently over 65 years of age. This means that more than 1 million are frail and almost 4 million are pre-fragile only in Spain.
- Conditions
- Frailty, Disability Physical, Old Age; Atrophy
- Trial name
- PRICA-POWFRAIL (NCT05772910)
- Testing
- EDUcation, EXERcise, EDU-EXER
- Volunteers
- 110 people
- Sponsor
- University of Cadiz
Dementia, Neurocognitive Disorders
Effect of Individual Reminiscence Therapy in the Elderly People With Neurocognitive Disorders
This research aims to evaluate the ability of individual reminiscence therapy (RT), using a simple reminiscence format, to improve the overall cognitive function, memory, emotional status and quality of life (QoL) of older adults…
- Conditions
- Dementia, Neurocognitive Disorders, Cognitive Impairment, Cognitive Dysfunction
- Trial name
- NCT04658394
- Testing
- Reminiscence therapy
- Where
- 13 sites in Portugal
- Volunteers
- 122 people
- Sponsor
- Rsocialform - Geriatria, Lda
Cancer Abdomen, Elderly (People Aged 65 or More)
Functional Decline and Quality of Life After Gastrointestinal Cancer Surgery in Older Adults
This prospective cohort study will evaluate functional decline, health-related quality of life, and long-term oncological outcomes in adults aged 65 years and older undergoing curative-intent resective surgery for…
- Conditions
- Cancer Abdomen, Elderly (People Aged 65 or More), Quality of Life, Sarcopenia in Elderly
- Trial name
- NCT07412379
- Where
- Colombia
- Volunteers
- 590 people
- Sponsor
- Hospital Universitario Mayor Méderi
Frail Elderly, Exercise Therapy
A Multi-component Intervention in Frail Community-dwelling Older People
This study evaluates if a multi-component intervention, respecting the characteristics of frail older person and increasing intensity and challenge of exercises according to frail older person capacity/evolution will induce…
- Conditions
- Frail Elderly, Exercise Therapy, Physical Therapy Techniques
- Trial name
- MIF (NCT02918682)
- Testing
- Exercise - FIRST PHASE, Exercise - SECOND PHASE, Exercise - FOURTH PHASE
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Delirium, Hip Fracture
Evaluating the Addition of Regional Analgesia to Reduce Postoperative Delirium in Patients Having Hip Fracture Surgery.
Post operative delirium is common after hip fracture surgery and is associated with increased length of hospital stay, delayed recovery and increased mortality.
- Trial name
- RASAPOD (NCT02689388)
- Testing
- Femoral Nerve Block
- Where
- New Zealand
- Volunteers
- 20 people
- Sponsor
- Auckland City Hospital
COVID-19
Clinical and Biological Predictors of COVID-19 Disease in Older Patients
The project is an observational, prospective study. Its aim is to deepen our understanding of COVID-19 in older patients hospitalized and diagnosed with COVID-19.
- Trial name
- NCT04348396
- Where
- 3 sites in Italy
- Volunteers
- 300 people
- Sponsor
- Istituto Nazionale di Ricovero e Cura per Anziani
Frailty
Longitudinal Study of Frailty in Shanghai Older People
To investigate the prevalence of Frailty in community older residents.
- Trial name
- NCT04650789
- Where
- China
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Atrial Fibrillation
Multidisciplinary Team Approach to Prescribe Antithrombotic Therapy in Older People With Atrial Fibrillation
Antithrombotic drugs, which include antiplatelet and anticoagulant therapies, are used to prevent and treat many cardiovascular disorders.
- Trial name
- ANTITHROMBOTEA (NCT04932603)
- Testing
- Standard of care, with intervention of the multidisciplinary team
- Where
- France
- Volunteers
- 833 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Mental Health Issue, Frailty
Brief Health Promotion Intervention for Older People in Mental Health
The goal of this observational study is to test the delivery of brief health promotion advice with supporting information leaflets as part of standard clinical consultation for older people attending a community mental health…
- Trial name
- NCT06127680
- Testing
- Brief Health Promotion Advice
- Where
- Ireland
- Volunteers
- 20 people
- Sponsor
- University College Cork
Sarcopenia
Multicomponent Intervention for Physical Frailty and Sarcopenia
The SPRINTT study will evaluate the efficacy of a multicomponent intervention programme (physical activity, nutritional counselling/dietary intervention, and information and communications technology intervention) compared with a…
- Trial name
- SPRINTT (NCT02582138)
- Testing
- Multicomponent intervention (MCI), Healthy Aging Lifestyle Education (HALE)
- Where
- Italy
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Parkinson Disease, Aging
SocIal ROBOTics for Active and Healthy Ageing
The study was designed to test the acceptability of the Si-Robotics system in a group of 20 subjects with Parkinson's Disease at an early stage, during a rehabilitation treatment based on Irish dancing.
- Trial name
- SI-ROBOTICS (NCT05005208)
- Testing
- rehabilitation program with the support of the technological platform SI-ROBOTICS
- Where
- 2 sites in Italy
- Volunteers
- 20 people
- Sponsor
- Istituto Nazionale di Ricovero e Cura per Anziani
Accidental Falls, Postural Balance
Feasibility of High-intensity Functional Exercise With Simultaneous Cognitive Challenge for Older People With Falls Risk
This study aims to evaluate the feasibility of a high-intensity functional exercise program with simultaneous cognitive challenge (HIFE+cog) among older people at risk of falls.
- Conditions
- Accidental Falls, Postural Balance, Gait, Cognition
- Trial name
- NCT06774508
- Testing
- HIFE+cog, HIFE
- Where
- Sweden
- Volunteers
- 33 people
- Sponsor
- Umeå University