Clinical trials: Older Women
Mammography, Medical Overuse
A Multi-Level Strategy for De-implementing Mammography Overuse Among Older Women
This project aims to advance methodological and theoretical approaches for developing, selecting, refining, and piloting a multilevel de-implementation strategy to reduce the overuse of screening mammography in women aged ≥75…
- Conditions
- Mammography, Medical Overuse, Evidence-based Practice, Older Adults
- Trial name
- NCT07511621
- Testing
- Enhanced Usual Care (EUC), Multilevel De-Implementation Strategy
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Columbia University
Urinary Incontinence, Falls, Accidental
Continence Across Continents to Upend Stigma and Dependency
To determine whether women exposed to the continence promotion intervention will report improved urinary symptoms and quality of life, and lower incontinence-related stigma and falls than women who receive a control intervention…
- Conditions
- Urinary Incontinence, Falls, Accidental, Quality of Life, Stigma
- Trial name
- CACTUS-D (NCT01858493)
- Testing
- Continence promotion group education workshop
- Where
- 4 sites in Canada, France and 1 more
- Volunteers
- 910 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal
Breast Cancer
Testing Conversation Aid in Practice
The goal of this research study is to develop and test a website to help primary care providers (PCPs) discuss the pros and cons of mammography with women aged 75 and older and to help participants make decisions about…
- Trial name
- NCT06011434
- Testing
- Mammography Screening Conversation Aid
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Frailty
Ghrelin in Healthy and Frail Older Women
The purpose of this research study is to see if giving women a hormone called "ghrelin" will increase levels of growth hormone in the blood and increase appetite.
- Trial name
- NCT00520884
- Testing
- Ghrelin Infusion - Healthy, Ghrelin Infusion - Frail
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Kidney Failure, Chronic
Advance Care Planning With Older Patients Who Have End-stage Kidney Disease
This study will test the feasibility of carrying out a randomised controlled trial, incorporating a mixed methods process evaluation, to evaluate advance care planning with older patients who have end-stage kidney disease.
- Trial name
- ACREDiT (NCT02631200)
- Testing
- Advance care plan
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- Queen's University, Belfast
Incontinence, Urge, Incontinence Stress
Think Dry: Optimalisation of Diagnostic Process of Urinary Incontinence in Older People
Urinary incontinence is an increasing medical and socio-economical problem. 44% of the elderly (>65 years) women and 28% of the elderly men suffer from unwilling urine loss. Moreover, this percentages increase with age.
- Conditions
- Incontinence, Urge, Incontinence Stress, Incontinence, Daytime Urinary, Incontinence, Nighttime Urinary
- Trial name
- NCT04094753
- Testing
- Blood Sample, Renal Function Profile, Frequency Volume Chart
- Where
- Belgium
- Volunteers
- 202 people
- Sponsor
- University Hospital, Ghent
Bone Resorption, Osteoporosis
The Effect of Protein Supplementation on Bone Health in Healthy Older Men and Women
Women and men consuming a low protein diet may be at risk for bone loss. The purpose of this study is to determine whether a daily protein supplement will improve bone health among healthy older adults.
- Trial name
- NCT00421408
- Testing
- Whey protein supplement
- Where
- 2 sites in United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Yale University
Body Composition, Healthy
Whey Protein Supplementation Associated With Resistance Training on Health Indicators in Trained Older Women
The main purpose of the present study was to investigate the effects of whey protein supplementation associated with resistance training on muscle strength, body composition, muscle quality, cellular hydration, cardiometabolic…
- Trial name
- NCT03247192
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Londrina
Muscle Protein Synthesis, Sarcopenia
The Impact of a Whole-food Animal-based Versus Plant-based Protein Rich Meal on Muscle Protein Synthesis
Rationale: Food intake stimulates muscle protein synthesis rates. The magnitude of the anabolic response to feeding forms a key factor in regulating muscle mass maintenance.
- Trial name
- MeaL (NCT05151887)
- Testing
- Muscle protein synthesis
- Where
- Netherlands
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Depression, Physical Functional Performance
Eccentrically Reinforced Resistance Training vs. Traditional Resistance Training in Sedentary Older Women
There are easily accessible and safe strategies, such as physical exercise, that can contribute to reducing depressive symptoms and to the preservation of physical and executive function in elderly women.
- Conditions
- Depression, Physical Functional Performance, Executive Function
- Trial name
- NCT05910632
- Testing
- Eccentrically strengthened resistance exercise, Traditional resistance training
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Federal University of Vicosa
Urinary Incontinence in Old Age, Sedentary Behavior
Urinary Incontinence and Sedentary Behaviour in Nursing Homes
The increase of the older adult population in the past years has generated an important impact on chronic conditions and geriatric syndromes like dementia, falls and urinary incontinence (UI).
- Trial name
- OsoNaH (NCT04297904)
- Testing
- Sedentary behaviour, Urinary Incontinence
- Where
- 15 sites in Spain
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of Vic - Central University of Catalonia
Diabetes Mellitus, Type 2, Healthy
Sedentary Behavior in Older Women With and Without Type 2 Diabetes
Sedentary behavior has been linked to cardiovascular morbidity and mortality, and is particularly common in older adults with type 2 diabetes.
- Trial name
- SitWise (NCT04262128)
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Frail Elderly, Aging
Targeting Aging With a Ketone Ester for Function in Frailty
This study aims to find out if a food supplement that contains a naturally occurring substance, ketones, can help to improve strength and general wellness in adults at, or over the age of 65 years who are experiencing a slight…
- Conditions
- Frail Elderly, Aging, Immune Function, Muscle Function
- Trial name
- TAKEOFF (NCT06645847)
- Testing
- Ketone ester
- Where
- 3 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Buck Institute for Research on Aging
Cardiovascular, Disease
Physical Activity Program for Cardiac Health Among Older African American Populations
Cardiovascular Diseases (CVD) are the leading cause of morbidity and mortality globally, and older African Americans (AAs) living in rural areas are disproportionately affected by this healthcare problem.
- Trial name
- NCT04866732
- Testing
- Physical Activity Cardiac Health Program
- Volunteers
- 30 people
- Sponsor
- University of Alabama, Tuscaloosa
Walking
Effects of Brisk Walking Combined With Tai Chi Chuan on Health-Related Physical Fitness and Selected Health Parameters Among Older Chinese Women
Aging is a problem that exists in many countries in the world. China has a large population base and a large number of elderly people.
- Trial name
- NCT04936672
- Testing
- Brisk walking and Tai Chi Chuan
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bai Xiaorong
Social Isolation in Older Adults, Poverty
Multimodal Training With Immersive Virtual Reality to Improve the Cognitive Health and Emotional Well-being of Older Women Living Alone
This study aims to evaluate the effectiveness of an immersive virtual reality-based multimodal intervention (VirtualDONA) to improve cognitive health and emotional well-being in older women living alone and at risk of poverty.
- Trial name
- VirtualDONA (NCT06956794)
- Testing
- VirtualDONA Multimodal Program
- Where
- 2 sites in Spain
- Volunteers
- 80 people
- Sponsor
- Consorci Sanitari de Terrassa
Breast Cancer
A Phase IV Study to Collect Data on the Efficacy and Safety of RIBociclib in Older Women With Breastcancer
The RibOB study is a prospective, open lable, single arm trial which will evaluate the clinical efficacy, overall safety and tolerability of ribociclib in combination with letrozole in older women (≥70 years) with HR+/HER2- aBC…
- Trial name
- RibOB (NCT03956654)
- Testing
- Ribociclib
- Where
- Belgium
- Volunteers
- 78 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Performance Enhancement
Functional vs Traditional Training in Older Women's Health
This study investigates how balance, mobility, strength, gait speed, and health-related quality of life in older adults (65+) are affected after an 8-week training period using the Norwegian national concept for older adults…
- Trial name
- NCT05551000
- Testing
- Experimental, comparator and control
- Where
- Norway
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Physical Activity, eHealth Literacy
Digital Literacy Training and Acceptance of Physical Activity Apps in Older Women
This randomized controlled study examined whether a structured digital literacy training program could improve eHealth literacy, acceptance of physical activity applications, and behavioral intentions among older women.
- Conditions
- Physical Activity, eHealth Literacy, Technology Acceptance
- Trial name
- NCT07515898
- Testing
- Digital Literacy Training Program
- Where
- Lithuania
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Type 1 Diabetes Mellitus, Diabetic Nephropathy
Impact of c242T Polymorphism of p22phox in Diabetic type1 Nephropathy
The physiopathology of diabetic nephropathy (DN) is unclear. To investigate risk factor, the investigators choose to look about some oxidative stress genes. Today a one-gene explanation is not really possible.
- Trial name
- NEPHRODIANOX (NCT01371955)
- Where
- France
- Volunteers
- 162 people
- Sponsor
- University Hospital, Grenoble