Clinical trials: Older Women
Renal Disease, End Stage, Palliative Care
Improving Medical Decision Making for Older Patients With End Stage Renal Disease
The overall objective of this study is to reduce the burden of chronic kidney disease (CKD) and its consequences for an aging U.S. population.
- Conditions
- Renal Disease, End Stage, Palliative Care, Decision Aids
- Trial name
- VIDEO-KD (NCT04347629)
- Testing
- Advance Care Planning Video Decision Aid
- Where
- 9 sites in United States
- Volunteers
- 456 people
- Sponsor
- Tufts Medical Center
Sarcopenia
Effects of a Resistance Training Program in Older Women With Sarcopenia
This is a randomized clinical trial with a control group that will test how periodized resistance training will impact measures of sarcopenia in older women who have been identified as presarcopenic or sarcopenic.
- Trial name
- RESTORE-ME (NCT02628145)
- Testing
- Resistance Training Intervention, Active Control Group
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Rhode Island
Chronic Kidney Diseases
Enhancing Physical Function in Older Adults With Chronic Kidney Disease
The goal of this pilot randomized controlled trial is to examine the feasibility and safety of a 12-week high-velocity resistance training (HVRT) intervention in older adults with chronic kidney disease (CKD) stages 4-5 and to…
- Trial name
- EPIC (NCT06738394)
- Testing
- High-Velocity Resistance Training, Attention
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Wake Forest University Health Sciences
Overweight and Obesity
Web-Based Weight Loss & Weight Maintenance Intervention for Older Rural Women, Also Known as Women Weigh-in for Wellness
This project will evaluate an Internet delivery strategy to address weight loss and maintenance among rural midlife and older women.
- Trial name
- NCT01307644
- Testing
- Experimental: Web-based only (WO) weight intervention, Experimental: WO plus peer-led discussion board (WD), Experimental: WO & professional email counseling (WE)
- Where
- United States
- Volunteers
- 301 people
- Sponsor
- University of Nebraska
Ovarian Cancer
Use of Palliative Performance and Symptom Distress Scales in Older Patients With Advanced Ovarian Cancer
RATIONALE: Measuring changes in performance status and symptoms distress in patients with cancer may help doctors predict how patients will respond to treatment, and may help the study of cancer in the future.
- Trial name
- NCT01175967
- Testing
- Palliative Performance Scale version 2 (PPSv2), McCorkle Symptom Distress Scale (SDS), Geriatric Assessment
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Multimorbidity, Hypertension
Development and Validation of a Comprehensive Management Service Package for Older Adults With Multimorbidity
This study aims to test a new comprehensive management service package for older adults with two or more chronic conditions (multimorbidity).
- Conditions
- Multimorbidity, Hypertension, Diabetes Mellitus, Coronary Artery Disease
- Trial name
- COMPASS (NCT07151430)
- Testing
- Service Package Group
- Volunteers
- 358 people
- Sponsor
- Xuanwu Hospital, Beijing
Infections, Papillomavirus, Papillomavirus Vaccines
Study to Evaluate the Efficacy of the Human Papillomavirus Vaccine in Healthy Adult Women of 26 Years of Age and Older
This is a multicentre study in which women were planned to receive either the Human Papillomavirus Vaccine (HPV) vaccine or control.
- Trial name
- NCT00294047
- Testing
- Cervarix
- Where
- 75 sites in United States, Australia and 10 more
- Volunteers
- 5,752 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Acute Kidney Injury
Frailty and Outcomes in Critically Ill Patients Receiving CRRT
This nationwide observational cohort study will investigate the association between frailty, chronological age, and clinical outcomes in critically ill patients receiving continuous renal replacement therapy (CRRT) in Sweden.
- Trial name
- CRRT-AF (NCT07837219)
- Volunteers
- 22,000 people
- Sponsor
- Karolinska Institutet
Type 2 Diabetes Mellitus (T2DM)
Effect of Tai Chi Versus Moderate-intensity Combined Exercise Training on Cardiovascular Health and Physical Functional Performance in Older Men and Women With T2DM: the Tai Chi Intervention for Diabetes Management During Aging (TIDA) Study
This randomized, single-blind, controlled clinical trial compares the effects of a 12-week Tai Chi program versus moderate-intensity combined exercise (MICE) training on cardiovascular health, glycemic control, and physical…
- Trial name
- TIDA (NCT07131761)
- Testing
- Tai chi, Moderate-Intensity Combined Exercise (MICE), Control ( No Exercise )
- Volunteers
- 66 people
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Healthy Aging
The Effects of Different Intensity Training on Dynamic and Static Balance of Elderly
In this study, investigators tried to find a useful and safe way of training for the elderly population which can help this population to improve their fitness factors as fast as possible.
- Trial name
- NCT04901520
- Testing
- High Intensity Training, Moderate Intensity Training, Low Intensity Training
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Osteoporosis, Vertebral Fractures
The Effect of Exercise on Physical Function in Older Women With Osteoporosis and a History of Vertebral Fracture
The study is a parallel-group single blinded randomized controlled trial, examining the effect of exercise on physical function in older women with osteoporosis and a history of vertebral fracture.
- Trial name
- NCT02781974
- Testing
- Exercise
- Where
- Norway
- Volunteers
- 149 people
- Sponsor
- Oslo Metropolitan University
Weight Loss
Exercise Time in Sedentary Middle-aged Female
The exercise time is an important factor among the medical guides for weight loss; however, there is still little knowledge about exercise duration paths in middle-aged and older women.
- Trial name
- NCT01851837
- Testing
- Exercise time
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- P.L.Shupik National Medical Academy of Post-Graduate Education
Metastatic Breast Cancer
To Compare Treatment With Doxorubicin or Capecitabine for Metastatic Breast Cancer in Women 60 Years and Older
The main purpose of this study is to compare treatment with either pegylated liposomal doxorubicin or capecitabine as first line chemotherapy for metastatic breast cancer in women 60 years and older.
- Trial name
- NCT00082095
- Testing
- Pegylated liposomal doxorubicin, Capecitabine
- Where
- 27 sites in United States
- Volunteers
- 62 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Aged, Exercise Therapy
Comparative Effects of Multicomponent Training Concerning Elastic Band Training on Physical Fitness, Postural Balance, and Health-related Quality of Life in Older Women
Objective: To compare the effects of MCT versus EBT on functional fitness, postural balance, and HRQoL in older women. Methods: Single-blind, parallel-group randomized controlled trial lasting 16 weeks (2 sessions/week, 60 min).
- Conditions
- Aged, Exercise Therapy, Physical Performance
- Trial name
- RCT (NCT07561879)
- Testing
- Multicomponent training program, Elastic band training program
- Volunteers
- 40 people
- Sponsor
- Universidad Católica del Maule
Aging, Healthy
Effect of Two Years of Resistance Training in Cardiac Function in Older Women: a Randomized Controlled Trial
Purpose: This study aimed to determine the effect of 48 weeks of resistance training (RT) on cardiac function in older women. Methods: Sixty-four older women (≥ 60 years), physically independent, were selected for this study.
- Trial name
- NCT06160141
- Testing
- Resistance training
- Where
- Brazil
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Londrina
Sickle Cell Disease, Sickle Cell Trait
Bone Loss, Physical Function and Frailty in Older Women With Sickle Cell Trait Sickle Cell Trait
This is a cross-sectional, clinical research study comparing postmenopausal women of African Descent (AD) with different hemoglobin genotypes: normal and sickle cell trait (SCT). This research study has two purposes.
- Trial name
- NCT07083531
- Testing
- Healthy volunteers without SCT, Healthy volunteers with SCT
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- UConn Health
Breast Cancer Screening
Messaging Strategies to Reduce Breast Cancer Over-screening in Older Women
This is an online survey experiment with data collection over 2 time points two weeks apart. This is Aim 2 of a three-aim R01 project; overall project goal is to better understand how messages from different sources interact to…
- Trial name
- NCT05821023
- Testing
- messages
- Where
- United States
- Volunteers
- 4,173 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Overweight , Obesity
Health Effects of a Walking Program in a High-Quality Tourism Environment for Older Women
The goal of this randomized controlled trial is to evaluate the effect of environmental context on the health benefits of a standardized walking program in sedentary, overweight older women (aged ≥60 years, BMI ≥24.0 kg/m²) .
- Trial name
- NCT07477262
- Testing
- Walking Program in Natural Tourism Environment, Walking Program in Conventional Institutional Environment
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Yu-fan Li
Infertility, Female, Ovarian Stimulation
Double Ovarian Stimulation as Accumulation Strategy for Older Infertile Patients With Suboptimal Ovarian Response
Patients with infertility of the older age group of 37-42 years - a large cohort of patients of reproductive medicine. Two possible causes reduce their probability of pregnancy - an increasing age and a decrease of the ovarian…
- Conditions
- Infertility, Female, Ovarian Stimulation, In Vitro Fertilisation
- Trial name
- NCT03400722
- Testing
- Pergoveris, Clomiphene
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- Nova Clinic, Russia
Osteoporosis, Osteoporosis, Postmenopausal
EFFECT OF FLOW RESTRICTION ON BONE QUALITY WITHIN A MULTICOMPONENT EXERCISE PROGRAM FOR OLDER WOMEN WITH OSTEOPOROSIS.
HYPOTHESIS: A multicomponent exercise program where strength exercises are performed with blood flow restriction obtains better values in densitometry and bone mass of osteoporotic patients with respect to the same multicomponent…
- Conditions
- Osteoporosis, Osteoporosis, Postmenopausal, Bone Diseases, Exercise
- Trial name
- NCT04760145
- Testing
- Multicomponent Exercise with Blood Flow Restriction, Multicomponent Exercise without Blood Flow Restriction
- Volunteers
- 94 people
- Sponsor
- Universitat Internacional de Catalunya