Clinical trials: Older Women
Sarcopenia, Chronic Kidney Disease
Physical Rehabilitation and Chronic Kidney Disease
Older patients with chronic renal failure suffer from sarcopenia. Loss of muscle function is associated with increased morbidity and mortality. Currently few treatment are available.
- Conditions
- Sarcopenia, Chronic Kidney Disease, Older
- Trial name
- IMPREPA (NCT03671343)
- Testing
- Physical rehabilitation
- Where
- 2 sites in France
- Volunteers
- 90 people
- Sponsor
- Hospices Civils de Lyon
Breast Cancer
Exercise in Older Women With Breast Cancer During Systemic Therapy
BREACE is a prospective randomized controlled trial. The aim is to investigate the effect of an exercise-based intervention among older participants with breast cancer treated with adjuvant or first-line systemic therapy.
- Trial name
- NCT03656731
- Testing
- Breast cancer exercise intervention
- Where
- Denmark
- Volunteers
- 68 people
- Sponsor
- Herlev and Gentofte Hospital
Infertility
Infertility Therapy for Women Age Thirty-eight and Older
This study will determine the most effective treatment strategy for infertile couples who present when the female partner is 38 years to the 43rd birthday and the couples are determined to have a reasonable chance for success.
- Trial name
- FORT-T (NCT00246506)
- Testing
- intrauterine insemination, in vitro fertilization
- Where
- 4 sites in United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Female Breast Cancer, Older Adults
Melatonin Supplementation and Exercise Program in Breast Cancer Women
Introduction: Breast cancer (BC) remains the leading cause of cancer in women with nearly 1.4 million new cases worldwide annually and 27.000 in Spain.
- Conditions
- Female Breast Cancer, Older Adults, Exercise Trainning Progrmam
- Trial name
- MEXBSO (NCT06696378)
- Testing
- Melatonin 6 mg
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- University of Valladolid
Breast Cancer Females, Frailty
Frailty and Health-related Quality of Life in Older Women With Breast Carcinoma
This study addresses a critical gap in the care of older women with breast cancer, a population often underrepresented in clinical research despite their increased vulnerability to treatment-related complications.
- Trial name
- NCT07159321
- Testing
- Comprehensive geriatric assessment, European Organization for Research and Treatment-Quality of life questionnaire, Clinical Frailty Scale
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Muscle Weakness
Effects of Creatine Supplementation on Muscle Mass and Function Among Older Women Subjected to Resistance Training
To determine, in a double blind trial, the effects of creatine supplementation during 12 weeks on muscle mass and function of community living older women subjected to resistance training.
- Trial name
- NCT02188849
- Testing
- Resistance exercise training, Creatine
- Where
- Chile
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Chile
Osteoporosis
Soy and Isoflavones Effect on Bone
The purpose of this study is to test the effect of 1 year of added dietary soy protein and/or soy isoflavones on bone mineral density in late postmenopausal women.
- Trial name
- NCT00668447
- Testing
- Soy Isolate, Control protein, Novasoy isoflavones
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- United States Department of Agriculture (USDA)
Weight Loss, Obesity
A High Protein Weight Loss Intervention for Sarcopenic Obesity in Women
The purpose of the trial is to assess the effects of combining regular, generous intakes of high quality protein (primarily from lean pork and other animal source proteins) with calorie restriction on functional status and lean…
- Trial name
- POWR-UP (NCT02033655)
- Testing
- Protein supplementation, Diet counseling and group education lessons
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Duke University
Renal Cell Carcinoma, Ovarian Carcinoma
OPTI - DOSE: Optimal Dosing of Oral Anticancer Drugs in Older Adults
The study hypothesis is that a lower starting dose of anticancer tablet treatments can lead to better treatment tolerability in older patients, while the benefits of treatment can be the same.
- Conditions
- Renal Cell Carcinoma, Ovarian Carcinoma, Thyroid Carcinoma, Breast Carcinoma
- Trial name
- OPTI-DOSE (NCT05949424)
- Testing
- Olaparib, Lenvatinib, Sunitinib
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- University Medical Center Groningen
Breast Cancer
Art Therapy Intervention for Breast Cancer Patients
As studies continue to debate the effects of quality of life on survival, increased attention is being focused on investigating complementary alternative therapies to boost overall total health in cancer patients .
- Trial name
- NCT01220960
- Testing
- art therapy
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- Dr. Sarkis Meterissian
Sarcopenia
Exercise Protocols in Postural Balance Of Elderly Women
To determine and compare the effects of a training program with Pilates and Facilitation Neuromuscular Proprioceptive on balance and function in elderly women.
- Trial name
- NCT02278731
- Testing
- training program
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual do PiauÍ
Cardiovascular, Disease
Physical Activity Program for Cardiac Health Among Older African American Populations
Cardiovascular Diseases (CVD) are the leading cause of morbidity and mortality globally, and older African Americans (AAs) living in rural areas are disproportionately affected by this healthcare problem.
- Trial name
- NCT04866732
- Testing
- Physical Activity Cardiac Health Program
- Volunteers
- 30 people
- Sponsor
- University of Alabama, Tuscaloosa
Breast Cancer
S0029 Docetaxel in Treating Older Women With Metastatic Breast Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of docetaxel in treating older women who have metastatic…
- Trial name
- NCT00025493
- Testing
- docetaxel
- Volunteers
- 27 people
- Sponsor
- SWOG Cancer Research Network
Ovarian Cancer, Neoadjuvant Chemotherapy
Prehabilitation During the Neoadjuvant Window of Opportunity in Older Women With Ovarian Cancer
The purpose of this study is to test the effectiveness of a home-based, patient-tailored intervention, FIT4SURGERY, to promote physical activity among women with ovarian cancer undergoing neoadjuvant chemotherapy.
- Conditions
- Ovarian Cancer, Neoadjuvant Chemotherapy, Prehabilitation
- Trial name
- FIT4SURGERY (NCT05092763)
- Testing
- FIT4SURGERY, Healthy Lifestyle Control
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Northwestern University
Urinary Incontinence
Effects of Pilates Exercises Versus Pelvic Floor Muscle Exercises Among Elderly Women With Urinary Incontinence
To compare the effects of Pilates exercises versus pelvic floor muscle exercises among elderly women with urinary incontinence. The study is a single-blinded randomized clinical trial.
- Trial name
- NCT05341778
- Testing
- Shoulder bridge, Clam shell, Scissors
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Dow University of Health Sciences
Sarcopenia, Muscle Atrophy
Vitamin D and Resistance Exercise Training; Effects on Musculoskeletal Health in Frail Older Men and Women
This study aims to determine whether vitamin D3 supplementation is any more effective in improving musculoskeletal function when combined with exercise training compared with exercise training alone.
- Conditions
- Sarcopenia, Muscle Atrophy, Osteoporosis
- Trial name
- EXVITD (NCT02467153)
- Testing
- RET, Vitamin D3
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Immune Response, Inflammation
Effect of Blueberries on Immunity
This research study will test the effects of Blueberries on immune functions in overweight older men and postmenopausal women
- Trial name
- Blueberry (NCT05534893)
- Testing
- Blueberry powder group
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Aging
Energy Expenditure Responses to Acute Exercise in Older Women (Calorie Expenditure and Exercise)
In older, normal-weight women (60-75 yrs, BMI=18-28 kg/m2), an acute bout of higher-intensity (60% of maximum effort) aerobic exercise, in comparison to an isocaloric bout of lower-intensity (45% of maximum effort) exercise…
- Trial name
- CEE (NCT00988299)
- Testing
- exercise
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Prevention of Ischemic Stroke, Acute Non-cardioembolic Ischemic Stroke
A Study to Test Asundexian for Preventing a Stroke Caused by a Clot in Participants After an Acute Ischemic Stroke or After a High-risk Transient Ischemic Attack, a So-called Mini Stroke
Researchers are looking for a better way to prevent an ischemic stroke which occurs when a blood clot travelled to the brain in people who within the last 72 hours had: an acute stroke due to a blood clot that formed outside the…
- Conditions
- Prevention of Ischemic Stroke, Acute Non-cardioembolic Ischemic Stroke, High-risk Transient Ischemic Attack
- Trial name
- OCEANIC-STROKE (NCT05686070)
- Testing
- Asundexian (BAY2433334)
- Where
- 741 sites in United States, Argentina and 35 more
- Volunteers
- 12,327 people
- Sponsor
- Bayer
Breast Cancer
Comparison of Combination Chemotherapy Regimens in Treating Older Women Who Have Undergone Surgery for Breast Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug and giving them in different ways after surgery may kill more tumor cells.
- Trial name
- NCT00024102
- Testing
- Standard Treatment, capecitabine
- Where
- 334 sites in United States, Canada and 1 more
- Volunteers
- 633 people
- Sponsor
- Alliance for Clinical Trials in Oncology