Clinical trials: Older Women
Chronic Kidney Disease
Niaoduqing Granules in Older Adults With Impaired Kidney Function
This prospective real-world study will evaluate the clinical benefits of Niaoduqing Granules in older adults with impaired kidney function.
- Trial name
- NCT07741292
- Testing
- Intervention Name
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Huashan Hospital
Papillomavirus Infections
HPV Infections in Older Women
The purpose of this study is to determine risk factors for HPV infections in 25 to 65 year old women who report having used internet dating websites in the past year.
- Trial name
- NCT00743392
- Where
- United States
- Volunteers
- 503 people, healthy volunteers welcome
- Sponsor
- University of Washington
Cardiovascular Diseases, Diabetes Mellitus, Type 2
Exercise Training in Older Diabetic Women
Type 2 diabetics (non-insulin-dependent) are more than five times as likely to suffer an initial myocardial infarction (MI; heart attack) compared to nondiabetics.Female diabetics in particular, have a higher mortality rate for…
- Trial name
- NCT00341614
- Testing
- 3-month Exercise Training and Diet Education
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of San Francisco
Chronic Kidney Disease (CKD), Elderly
Sertraline and the Risk of Serious Adverse Events
The goal of this population-based cohort study is to assess the safety of initiating a new outpatient prescription of 50 mg/day of Sertraline, a higher dose, compared to 25 mg/day, a lower dose, in adults aged 65+ with low kidney…
- Conditions
- Chronic Kidney Disease (CKD), Elderly, Outpatient
- Trial name
- NCT07387120
- Testing
- Sertraline 50 mg, Sertraline 25 mg
- Where
- Canada
- Volunteers
- 6,893 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Breast Cancer Female
Pre-Operative Window of ET to Inform RT Decisions (POWER II)
This is a Phase III, multisite exploratory study for women ≥ 65 years of age with early stage estrogen receptor positive (ER+) breast cancer.
- Trial name
- POWER II (NCT06507618)
- Testing
- Tamoxifen, Letrozole, Anastrozole, or Exemestane
- Where
- 6 sites in United States
- Volunteers
- 354 people
- Sponsor
- University of Virginia
Social Cognition, Healthy Aging
Immersive Group Dance in Virtual Reality and Perceived Social Cohesion in Older Adults
This is a two-arm, parallel-group randomized controlled trial designed to evaluate the effects of an immersive virtual reality (VR)-based group dance program on perceived social cohesion among community-dwelling older adults…
- Conditions
- Social Cognition, Healthy Aging, Loneliness, Social Isolation
- Trial name
- VR-GD-COHESION (NCT07850479)
- Testing
- Immersive VR Group Dance Program, Conventional Light Physical Activity Program
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Nutrition, Healthy
The Impact of Plant-based Blends on Skeletal Muscle Protein Synthesis Rates in Older Adults
Lifestyle interventions such as physical activity and dietary habits are the most effective non-pharmacological strategies to combat the loss of muscle mass and the development of mobility limitations with aging.
- Trial name
- NCT05917223
- Testing
- Milk protein ingestion, Cron protein ingestion, Corn+Pea protein ingestion
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- McMaster University
Cardiovascular Diseases, Metabolic Syndrome
Effects of Canola Oil and Coconut Oil on Postprandial Metabolism in Older Adults With Increased Cardiometabolic Risk
The aim of this study is to investigate the postprandial effects of fat content and fatty acid composition of mixed meals on parameters associated with cardiometabolic diseases.
- Trial name
- NCT05208346
- Testing
- Mixed meals
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University of Bonn
Prevention of Stroke or Systemic Embolism, Atrial Fibrillation
A Study to Learn How Well the Study Treatment Asundexian Works and How Safe it is Compared to Apixaban to Prevent Stroke or Systemic Embolism in People With Irregular and Often Rapid Heartbeat (Atrial Fibrillation), and at Risk for Stroke
Researchers are looking for a better way to treat people with atrial fibrillation (AF) and prevent stroke or systemic embolism (blood clots travelling through the blood stream to plug another vessel).
- Trial name
- OCEANIC-AF (NCT05643573)
- Testing
- Asundexian (BAY2433334), Apixaban
- Where
- 1,069 sites in United States, Argentina and 36 more
- Volunteers
- 14,830 people
- Sponsor
- Bayer
Walking
Effects of Brisk Walking Combined With Tai Chi Chuan on Health-Related Physical Fitness and Selected Health Parameters Among Older Chinese Women
Aging is a problem that exists in many countries in the world. China has a large population base and a large number of elderly people.
- Trial name
- NCT04936672
- Testing
- Brisk walking and Tai Chi Chuan
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bai Xiaorong
Retinitis Pigmentosa
A Study to Investigate the Safety of DSP-3077 After a Unilateral Eye Injection in Male and Female Participants 18 Years of Age or Older With Retinitis Pigmentosa
The Goal of this study is to evaluate the safety, tolerability, and clinical responses following single dose of DSP-3077. Study enrolls both male and female patients in 3 cohorts with each cohort defined by visual acuity (VA)…
- Trial name
- NCT06891885
- Testing
- DSP-3077 Retinal Sheet Cohort 1, DSP-3077 Retinal Sheet Cohort 2, DSP-3077 Retinal Sheet Cohort 3
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Sumitomo Pharma America, Inc.
Diet, Food, and Nutrition
Resistance Exercise and Hydrolyzed Collagen Supplementation
This study aimed to investigate the effect of different doses of hydrolyzed collagen (HC) with resistance exercise (RE) on whole body collagen synthesis in healthy young and older males and females.
- Trial name
- NCT05932771
- Testing
- Experimental: Consumption of three different doses of hydrolyzed collagen (HC) with reistance exercise, Experimental: Consumption of two different doses of hydrolyzed collagen (HC) with reistance exercise
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Rob Erskine
Cancer
Vegetable Garden Feasibility Trial to Promote Function in Older Cancer Survivors
Cancer survivorship has been claimed a national priority, with a call to develop effective interventions that can prevent, delay, or mitigate the adverse effects and comorbidities in this high risk population.
- Trial name
- NCT02150148
- Testing
- Experimental: Mentored Gardening Intervention
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Alabama at Birmingham
Urinary Incontinence
Urinary Continence Index for Prediction of Urinary Incontinence in Older Women
This study will analyse existing data to establish a clinically useful index to predict those women who are more likely to become incontinent.
- Trial name
- NCT01479816
- Where
- 2 sites in United States
- Volunteers
- 702 people
- Sponsor
- Ananias Diokno
Obesity
TOSS Feasibility + Fitbit Community = Reduced Obesity in Older Black Women
The primary goal of this proposed physical activity (PA) intervention is to develop a realistic and an economical intervention to promote regular PA among older, overweight or obese Black women.
- Trial name
- NCT04114071
- Testing
- TOSS Feasibility + Fitbit Community = Reduced Obesity in Older Black Women
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Sarcopenia, Aging
Sarcopenia, Obesity, and Resistance Training
The purpose of this study was to examine the effects of resistance training on sarcopenic obesity in older women.
- Conditions
- Sarcopenia, Aging, Obesity
- Trial name
- NCT02681744
- Testing
- Resistance Training
- Where
- Brazil
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- University of Brasilia
Type 1 Diabetes Mellitus, Diabetic Nephropathy
Impact of c242T Polymorphism of p22phox in Diabetic type1 Nephropathy
The physiopathology of diabetic nephropathy (DN) is unclear. To investigate risk factor, the investigators choose to look about some oxidative stress genes. Today a one-gene explanation is not really possible.
- Trial name
- NEPHRODIANOX (NCT01371955)
- Where
- France
- Volunteers
- 162 people
- Sponsor
- University Hospital, Grenoble
Metabolic Syndrome
Exercise Program in Women With Metabolic Syndrome
The purpose of this study is to test whether a supervised mixed aerobic and strength training (MAST) program is effective in improving overall physical fitness and blood flow in the brain and lowering risk factors of coronary…
- Trial name
- NCT00929500
- Testing
- MAST program
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Beth Israel Deaconess Medical Center
Resistance Exercise Pressor and Neural Responses in Older Women
Blood Pressure Reactivity After Resistance Exercise in Older Women
The purpose of this study is to determine and compare the effects of two sessions of resistance exercise in blood pressure reactivity to a mental stress test in older hypertensive women.
- Trial name
- NCT03002714
- Testing
- Exercise
- Volunteers
- 10 people
- Sponsor
- University of Brasilia
Breast Carcinoma, Colorectal Adenocarcinoma
Vaccine Response With NT-I7
Background: People with cancer, and especially older people, have a weakened immune system (the defense system of the body). This is often caused by the treatments for cancer.
- Conditions
- Breast Carcinoma, Colorectal Adenocarcinoma, Bladder Carcinoma
- Trial name
- NCT04054752
- Testing
- Recombinant human IL-7-hyFc (NT-I7), Vaccine sequence 1, Vaccine sequence 2
- Where
- United States
- Sponsor
- National Cancer Institute (NCI)