Clinical trials: Olfaction Disorders
Breast Milk, Digestion
The Effect of Breast Milk Smell on Nutrition in Preterms
The study was planned to determine the effect of breast milk odor applied during gavage feeding on early feeding cues of preterm newborns, the transition time to oral feeding and abdominal perfusion.
- Conditions
- Breast Milk, Digestion, Nutrition, Smell Stimulation
- Trial name
- NCT04843293
- Testing
- Olfactory stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Perception, Self
Comparing the Olfactory Perception of a Fragrance-Loaded SpECs Over Time
The human olfactory system plays a crucial role in sensory perception, influencing emotional states, memory, and interpersonal interactions(1).
- Trial name
- NCT07383337
- Testing
- Fragrance
- Where
- Bahrain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Royal College of Surgeons in Ireland - Medical University of Bahrain
Smell Loss, Chronic Rhinosinusitis (CRS)
Cognitive and Immunologic Profiles of Patients With Olfactory Dysfunction After Smell Training
A research study to assess the baseline olfactory function, mental health status, clinical severity, and immunological profile in patients with smell loss.
- Trial name
- CIPOD (NCT07681973)
- Testing
- Smell Training
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Central Compartment Atopic Disease (CCAD)
Development of A Multi-section Olfactory Cleft Opacity Staging System in Patients With CCAD
This study aims to develop a modified CT scoring system to evaluate the association between olfactory cleft obstruction patterns and olfactory dysfunction in patients with central region atopic disease (CCAD).
- Trial name
- NCT07380945
- Testing
- Computer Tomography
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Anosmia, Hyposmia
The Clinical Applicability of the 'TIB' Olfactory Test Device
The aim of this study was to evaluate the validity and test-retest reliability of the 'TIB' Olfactory Test Device, a new olfactory test tool developed by Top International Biotech, Taipei, and to determine its normative values.
- Trial name
- NCT05152030
- Testing
- 'TIB' Olfactory Test, Traditional Chinese version of the University of Pennsylvania of Smell Identification Test (UPSIT-TC)
- Where
- Taiwan
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Taichung Veterans General Hospital
Head and Neck Cancer
Tissue Sample Collection From Patients With Head and Neck Cancer and From Healthy Participants
RATIONALE: Collecting and storing samples of tissue, saliva, and blood from patients with cancer and from healthy participants to study in the laboratory may help the study of cancer in the future.
- Trial name
- NCT00898638
- Testing
- biologic sample preservation procedure, medical chart review
- Where
- 4 sites in United States
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Covid19, SARS-CoV Infection
Olfactory Training for Olfactory Dysfunction After Coronavirus Disease - 19 (COVID-19)
It is a randomized controlled clinical trial study that aims to follow a sample of individuals with persistent olfactory dysfunction post-COVID-19.
- Conditions
- Covid19, SARS-CoV Infection, Olfactory Disorder, Anosmia
- Trial name
- NCT04764981
- Testing
- Essence oils
- Where
- Brazil
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Universidade do Estado do Pará
Postoperative Cognitive Dysfunction
Postoperative Cognitive Dysfunction: Correlations With Olfactory Dysfunction and Related Gene Changes
To study on the Postoperative Cognitive Dysfunction: Correlations With Olfactory Dysfunction and Related Gene Changes.To explore whether the olfactory dysfunction could be used as a predictor of POCD and to provide reference for…
- Trial name
- NCT02992600
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Han Yuan
Anxiety
"Pain and Emotional Changes on Relationships Between Anxiety and Olfaction"
Introduction: This prospective study aimed to assess the impact of olfaction on providing positive emotional responses and reducing dental anxiety and pain.
- Trial name
- NCT06066073
- Testing
- Lavender Oil, Distal Water
- Where
- Saudi Arabia
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Qassim University
Newborn Jaundice
Influence of Breast Milk Smell on Newborns Bilirubin Level, Duration of Time Phototherapy and Comfort in Newborns Receiving Phototherapyv
ABSTRACT Purpose: This research was done for the purpose of determining the impact of breast milk smell administered to term infants hospitalized in neonatal intensive care units (NICU) due to physiological jaundice on their…
- Trial name
- NCT05167474
- Testing
- breast milk smell
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Olfaction, Diet
The Effects of Acute Caloric Deprivation on Odour Identification and Food Reward
The purpose of this study is to determine how the modality of energy depletion can differently impact appetite hormones, ad libitum food intake, food hedonics, and olfaction.
- Conditions
- Olfaction, Diet, Exercise, Energy Depletion
- Trial name
- DEXDER (NCT02653378)
- Testing
- DIET, EX
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Habituation
Repeated Food Exposure Via the Olfactory and Gustatory Systems
Increasing exposure to a single orosensory cue without ingestion of additional energy may promote an increased rate of habituation, more rapid satiation, and reduced intake.
- Trial name
- NCT01651221
- Testing
- Habituation
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Parkinson Disease, MSA - Multiple System Atrophy
Exploring the Olfactory Mucosa, Blood and Urine for the Identification of Early Biomarkers of Parkinson's Disease, Atypical Parkinsonisms and Neurocognitive Disorders Due to Lewy Body Disease
Clinical diagnosis of Parkinson's disease (PD), multiple system atrophy (MSA) and dementia with Lewy bodies (DLB) is challenging, especially in the early stages.
- Conditions
- Parkinson Disease, MSA - Multiple System Atrophy, Lewy Body Dementia (LBD), Neurodegenerative Disease
- Trial name
- EXTRAORDINARY (NCT06846658)
- Where
- 3 sites in Italy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Surgery, Gallbladder
Smell Memory Method for Patients Before Surgery
The research is planned as a randomized controlled experimental at Erzurum Atatürk University Health Application and Research Center.
- Conditions
- Surgery, Gallbladder, Smell
- Trial name
- NCT06414980
- Testing
- Experimental
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Alzheimer Disease, Olfaction Disorders
Computerized Olfactory Test - Alzheimer Disease Mild Stage
This study evaluates the effectiveness of the smell tests that are used in early diagnosis of mild dementia.
- Trial name
- NCT03698760
- Testing
- Olfactory test
- Where
- Canada
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Jewish General Hospital
Parkinson Disease, Multiple System Atrophy
Diagnostic and Prognostic Biomarkers in Parkinson Disease
The overall goal of PROBE is to evaluate the feasibility and potential utility of three markers (alpha-synuclein, transcriptomic profiles and olfactory function) to determine the risk or prognosis of PD.
- Conditions
- Parkinson Disease, Multiple System Atrophy, Progressive Supranuclear Palsy
- Trial name
- PROBE (NCT00653783)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The Parkinson Study Group
Anosmia, Asymptomatic COVID-19
Longitudinal At Home Smell Testing to Detect Infection by SARS-CoV-2
The purpose of this study is to learn more about how to better track smell recovery in people who have been infected with the SARS-CoV-2 virus (which causes COVID-19).
- Conditions
- Anosmia, Asymptomatic COVID-19, COVID-19 Respiratory Infection, Influenza
- Trial name
- NCT05040659
- Testing
- AROMHA Longitudinal Smell Test
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Olfaction Disorders, COVID-19 Testing
Rapid Screening for Olfactory Disorders in Covid-19 Infection
Loss of smell is very frequently found in Europe during Covid-19 attack. This symptom was not initially expected as part of the classic symptomatology.
- Trial name
- OLFASCAN (NCT04696601)
- Testing
- Olfactory test
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Opioid Dependence, Obesity
The Impact of Methadone Maintenance Therapy on Food Reward Processing in Opioid Dependence
Methadone maintenance therapy (MMT) has shown clear efficacy for relieving opioid withdrawal symptoms and reducing the morbidity and mortality of opioid dependence.
- Trial name
- NCT03575273
- Testing
- Sniffin' Sticks Odor Identification and Hedonic Scale, Sucrose Taste Preference Assessment, Food Preferences Task
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Dental Anxiety, Dental Pain
Pain Perception: on Relationships Between Dental Anxiety and Olfaction
the objective of this study is to evaluate the ability of olfaction in obtaining positive emotional and behavioral responses toward dental anxiety and pain in patients undergoing different dental procedures.
- Conditions
- Dental Anxiety, Dental Pain, Essential Oil
- Trial name
- NCT05369936
- Testing
- Aromatherapy
- Where
- Saudi Arabia
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Qassim University