Clinical trials: Omega-3
Periodontitis, Therapeutics
Omega-3 Polyunsaturated Fatty Acids in Non-surgical Treatment of Periodontitis
Periodontitis is a chronic multifactorial inflammatory disease that lead to the loss of supportive tissues around the teeth with gradual deterioration of masticatory function and esthetics, resulting eventually in the decrease of…
- Conditions
- Periodontitis, Therapeutics, Fatty Acids, Unsaturated
- Trial name
- NCT04477395
- Testing
- fish oil, SRP only
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Lodz
Stage 0 Breast Carcinoma, Breast Neoplasms
Metformin and Omega-3 Fatty Acids in Woman With a History of Early Stage Breast Cancer
The purpose of this study is to determine whether it is feasible to give a combination of Metformin and omega-3 fatty acids for one year to women with a history of early stage breast cancer.
- Conditions
- Stage 0 Breast Carcinoma, Breast Neoplasms, Stage I Breast Carcinoma, Stage II Breast Carcinoma
- Trial name
- NCT02278965
- Testing
- Metformin, Omega-3 fatty acids
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Katherine D. Crew
ADHD
Omega-3 Fatty Acids Supplementation in ADHD
The overarching aim of the proposed study is to assess whether omega-3 fatty acids supplementation can augment the effects of methylphenidate in children with ADHD.
- Trial name
- NCT01777048
- Testing
- Omega-3 Fatty Acids Supplementation
- Where
- Switzerland
- Volunteers
- 8 people
- Sponsor
- University Hospital, Basel, Switzerland
Myocardial Infarction, Death, Sudden, Cardiac
Effect of High Dose Fish Oil Supplementation After Recent Heart Attack Using Magnetic Resonance Imaging
Doctors use magnetic resonance imaging (MRI) to obtain detailed pictures of the inside of the body. This study will evaluate a new MRI technique in people who have recently had a heart attack.
- Trial name
- OmegaREMODEL (NCT00729430)
- Testing
- Omega-3 Fatty Acids (Fish Oil Supplements)
- Where
- United States
- Volunteers
- 358 people
- Sponsor
- Brigham and Women's Hospital
Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
Efficacy Study of Vayarin in Children With Autism and Comorbid Attention Deficit Hyperactivity Disorder (ADHD)
This research study is carried out to examine the effects of Phosphatidylserine-Omega 3 supplements (i.e., Vayarin) among children with Autism Spectrum Disorder (ASD) and ADHD.
- Trial name
- NCT03115671
- Testing
- Vayarin
- Where
- Singapore
- Volunteers
- 24 people
- Sponsor
- Institute of Mental Health, Singapore
Obesity, Fertility
Effects of Dietary Omega-3 Fatty Acids on Reproductive Hormones in Obese Women
The United States has the highest prevalence of obesity among all countries surveyed in 2012 by the Organization for Economic Cooperation and Development.
- Trial name
- NCT01894581
- Testing
- LOVAZA, GnRH
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Metabolic Syndrome
Metabolic Actions of Omega-3 Fatty Acids
The metabolic syndrome raises the risk of heart disease and is currently at epidemic proportions in the U.S. It consists of 3 of the following components: central obesity, high triglycerides, low HDL, abnormal blood pressure and…
- Trial name
- NCT01896414
- Testing
- EPA (marine fatty acids)
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Polycystic Ovary Syndrome
Transcriptomic Profile of Adipose Tissue Following n-3 Polyunsaturated Fatty Acid (PUFA) Supplementation
Adipose tissue is a central organ involved in mediating metabolic health, and so the investigation of treatments which improve adipose tissue function is warranted.
- Trial name
- NCT01195155
- Testing
- LC n-3 PUFA (fish oil) Supplement
- Where
- 2 sites in Ireland
- Volunteers
- 10 people
- Sponsor
- The Adelaide and Meath Hospital
Depression
Folic Acid and Omega -3 Fatty Acid Supplementation in Depressed Older Adults
Our specific aim is to determine the impact of folic acid and omega-3 supplementation on the severity of depressive symptoms among depressed adults aged 65 and above.
- Trial name
- NCT00480207
- Testing
- folic acid, omega-3, vit B12
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- Prof. RH Belmaker
Heart Failure
GISSI-HF- Effects of n-3 PUFA and Rosuvastatin on Mortality-Morbidity of Patients With Symptomatic CHF
INTRODUCTION While pharmacological treatments specifically targeted to the cardio-circulatory system have been largely investigated, scanty controlled data are available concerning the role of dietary and metabolic approaches in…
- Trial name
- NCT00336336
- Testing
- n-3 PUFA, Rosuvastatin
- Where
- 337 sites in Italy, Switzerland
- Volunteers
- 6,975 people
- Sponsor
- Gruppo di Ricerca GISSI
Obese Adults, MDD
NUTRIMOOD-Inflammation and Depressive Comorbidity in Obesity: Modulation by Omega-3 Polyunsaturated Fatty Acids Status
A 12-week, randomized, placebo-controlled trial testing the efficacy of n-3 PUFA treatment (EPA, 2 g/day) in alleviating depressive symptoms in a subgroup of obese subjects with comorbid depression and low n-3 PUFA status (n-3…
- Trial name
- NCT07439744
- Testing
- Eicosapentaenoic acid (omega-3 fatty acid)
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Science and Technology Council, Taiwan
Attention Deficit Hyperactivity Disorder
The Effects of DHA on Attention Deficit and Hyperactivity Disorder
The purpose of this study is to determine whether docosahexaenoic acid (DHA) is effective in reducing Attention Deficit/Hyperactivity Disorder (ADHD) core symptoms in a clinical sample of children and adolescents with ADHD.
- Trial name
- DADA (NCT01796262)
- Testing
- docosahexaenoic acid, Wheat germ oil
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS Eugenio Medea
Healthy Volunteers
Metabolism of Omega-3 and Omega-6 During Healthy Aging
The purpose of this study is to determine the kinetics of 13C-eicosapentaenoic acid (EPA) and 13C-arachidonic acid (AA) in young and older participants
- Trial name
- NCT02957188
- Testing
- 13C eicosapentaenoic acid and 13C arachidonic acid
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Chronic Venous Leg Ulcers
Impact of Omega-3 Fatty Acid Oral Therapy on Healing of Chronic Venous Leg Ulcers in Older Adults
The purpose of this study is to test the efficacy of an oral, nutrient intervention containing the bioactive components of fish oil to promote healing of chronic venous leg ulcers (CVLUs) by reducing the chronic inflammation at…
- Trial name
- NCT03576989
- Testing
- EPA+DHA
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Ohio State University
Breast Cancer
Omega-3-Fatty Acid on Joint Symptoms Inducted by Aromatase Inhibitors
There are no data regarding the use of supplements to alleviate the musculoskeletal pain and stiffness inducted by the use of aromatase inhibitors.
- Trial name
- NCT00930527
- Testing
- Omega-3 Fatty Acid
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Columbia University
Multiple Sclerosis, Performance Enhancement
Effects of DHA in Patients With Multiple Sclerosis
This clinical trial will investigate the effects of combining therapeutic exercise with DHA supplementation in 100 patients with multiple sclerosis using a randomized controlled design.
- Conditions
- Multiple Sclerosis, Performance Enhancement, Supplemental Nutrition Assistance Program Education, Strength Outcomes
- Trial name
- DHAME (NCT07346703)
- Testing
- Docosahexaenoic Acid (DHA) Dietary Supplement, Sunflower Oil
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Francisco Javier Martínez Noguera
Healthy
Effect of Omega-3 Index on Cellular Metabolism and Quality of Life
Determine whether personal optimization of the Omega-3 index improves cellular metabolism and quality of life (according to the SF-36 form).
- Trial name
- NCT03159507
- Testing
- MAG-EPA
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- SCF Pharma
Major Depressive Disorder
Do Omega-3 Fatty Acids Have an Antidepressant Effect in Patients With Signs of Peripheral Inflammation?
In this study, the investigators will stratify depressed subjects a priori based on CRP levels to test the hypothesis that eicosapentaenoic (EPA) would be more efficacious to treat depression in subjects with high CRP levels…
- Trial name
- NCT03143075
- Testing
- Eicosapentaenoic acid enriched omega-3 fatty acids, 2 g/day
- Where
- Sweden
- Volunteers
- 95 people
- Sponsor
- Region Skane
Microbial Colonization, Infant Development
The Effects of Omega-3 PUFAs on the Infant Microbiome and Immunity
Prenatal supplementation with fish oil, rich in omega-3 polyunsaturated fatty acids, is widely recommended in Canada. The aim of this observational, prospective cohort study is to determine the effects of maternal fish oil…
- Trial name
- NCT03297801
- Testing
- Fish oil supplements
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Coronary Artery Disease, Depression
Treating Depression in Coronary Artery Disease With Omega-3 Fatty Acids
Depressive disorders are common in patients with Coronary Artery Disease (CAD), occurring in up to 47% of patients. Left untreated, these symptoms not only have a strong negative impact on quality-of-life, but also increase risk…
- Trial name
- CAROTID (NCT00981383)
- Testing
- Omega-3 Fatty Acid Supplement
- Where
- 2 sites in Canada
- Volunteers
- 92 people
- Sponsor
- Sunnybrook Health Sciences Centre
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