Clinical trials: Omega-3
Focus on Omega 3 Index on Recovery
Long-Term Omega-3 and Omega-3 Index >8%: Effects on Physiological Recovery
The Omega-3 Index measures how much of the Omega-3 fats EPA and DHA are built into red blood cell membranes. These fats are essential for health, but the body cannot make enough of them, so they must come from foods like oily…
- Trial name
- IMPROVE-8 (NCT07439601)
- Testing
- Oil Supplementation
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- St. Mary's University, Twickenham
Supplementation in Healthy Adults to Assess Impact on Omega 3 Index and Cardiometabolic Health
Change in Omega 3 Index in Healthy Adults With OmeGo or a Standard Omega-3 Oil Supplement
Omega-3 index is used as a proxy for an adequate intake of fish unsaturated fats in the diet. However, omega-3 supplements have not consistently shown the health benefits of eating fresh fish.
- Trial name
- NCT06802068
- Testing
- whole salmon oil, Cod liver oil
- Where
- 2 sites in United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Hofseth Biocare ASA
Cognitive Dysfunction, Alzheimer Disease
ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults
This randomized, double-blind, placebo-controlled pilot trial will evaluate the effects of alpha-linolenic acid (ALA) supplementation on cognitive function, blood-brain barrier integrity, and brain vascular health in older adults…
- Conditions
- Cognitive Dysfunction, Alzheimer Disease, Blood-Brain Barrier, Apolipoprotein E, Deficiency or Defect of
- Trial name
- NCT07392723
- Testing
- Alpha-Linolenic Acid (2.6 g/day)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Michal Schnaider Beeri, Ph.D.
Cardiovascular (CV) Risk, Atheroscleroses
Exploring Sustainable Alternatives to Marine Oils With Echium and Ahiflower Oils
This randomized, single-blind, crossover clinical trial aims to evaluate Echium oil and Ahiflower® oil as sustainable, plant-based alternatives to marine oils for omega-3 supplementation.
- Conditions
- Cardiovascular (CV) Risk, Atheroscleroses, Inflamation, Omega 3 Fatty Acids
- Trial name
- NCT07289919
- Testing
- Echium oil, Ahiflower oil, EPA capsules
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Heart Health Markers, Cardiovascular Diseases
Omega-3D: Omega-3 for Diet-Driven Health Disparities
The goal of this clinical trial is to learn whether omega-3 fatty acid supplementation can reduce inflammation-related biomarkers and improve cardiovascular health in healthy adult volunteers with different genetic backgrounds.
- Conditions
- Heart Health Markers, Cardiovascular Diseases, Omega 3 Fatty Acids
- Trial name
- NCT07078344
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Suboptimal Omega-3 Index
Enriched Eggs as a Sustainable Approach to Enhance Omega-3 Status in Elite Athletes
The study looked to identify the benefit of omega-3 enriched eggs on circulating omega-3 fatty acid profile of elite level athletes
- Trial name
- NCT07276113
- Testing
- omega-3 enriched eggs, non-enriched eggs
- Where
- 2 sites in Ireland, United Kingdom
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Omega 3 Fatty Acids
The Impact of Pastured Livestock Food Consumption on Fatty Acid and Metabolomic Profiles
The goal of this clinical trial is to evaluate the effects of consuming meat and eggs from regenerative/pastured versus conventional farming practices on health biomarkers in middle-aged adults.
- Trial name
- NCT06768775
- Testing
- Pastured Livestock Diet, Conventional Livestock Diet
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Utah State University
Krill Oil, Muscle Function
Investigating the Feasibility of Krill Oil Intervention to Improve Muscle Function in Adults With Long-term Conditions
This study will recruit 30 adults (men and women, aged 18 years and over) who will be randomly assigned to one of two groups in a 12-week double-blind pilot trial.
- Conditions
- Krill Oil, Muscle Function, Grip Strength, Long-Term Conditions
- Trial name
- KOMM (NCT07130513)
- Testing
- Krill oil supplementation, Control
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Glasgow
Omega 3, Treatment
Impact of Omega 3 in Treatment of Inappropriate Sinus Tachycardia
This study aimed to evaluate the effect of omega-3 supplementation on heart rate (HR) control and heart rate variability (HRV) in children with inappropriate sinus tachycardia (IST).
- Conditions
- Omega 3, Treatment, Inappropriate Sinus Tachycardia
- Trial name
- NCT07138131
- Testing
- Omega 3, Standard follow-up
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Benha University
Omega 3 Fatty Acids, Coronary Arterial Disease (CAD)
Investigation of the Effects of Omega-3 Supplementation in Chronic Kidney Disease Patients Diagnosed With Coronary Artery Disease and Dyslipidemia
Chronic kidney disease (CKD) is characterized by the slow, progressive, and irreversible loss of kidney function. Uremic toxins in CKD patients trigger an inflammatory response driven by various cytokines, chemokines, and other…
- Conditions
- Omega 3 Fatty Acids, Coronary Arterial Disease (CAD), Chronic Kidney Disease(CKD)
- Trial name
- NCT07127068
- Testing
- Omega-3 Suplementation, No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- University of Beykent
Diode Laser Therapy, Omega 3
Adjunct Use of Diode Laser Therapy and Omega 3 Gel in Local Drug Delivery Approach on The Treatment of Localized Aggressive Periodontitis
This study aims to evaluate and compare the effect of combination therapy between diode laser and omega3 gel in the local drug delivery approach as an adjunct to scaling and root planning on the management of localized aggressive…
- Conditions
- Diode Laser Therapy, Omega 3, Localized Aggressive Periodontitis
- Trial name
- NCT07056257
- Testing
- Scaling-root planning (SRP), Scaling-root planning (SRP)+ laser therapy, Scaling-root planning (SRP)+ omega 3 gel
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Tanta University
Nutrition, Absorption, Metabolism and Excretion in Healthy Volunteers
Bioavailability of Omega-3 Fatty Acids From Fish Oil Supplements
This study is investigating whether a new type of fish oil supplement, in the form of soft chews, leads to better absorption of omega-3s in the body compared to traditional fish oil capsules.
- Conditions
- Nutrition, Absorption, Metabolism and Excretion in Healthy Volunteers, Fish Oils, Omega 3 Fatty Acids
- Trial name
- Ocean's O3 (NCT06665464)
- Testing
- Fish oil supplement 1, Fish oil supplement 2
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Wageningen University and Research
Fatty Acids, Omega-3
Evaluation of the Nutritional Status of Omega-3 Fatty Acids and the Possible Influences of Dietary Patterns and Different Socioeconomic Factors, in a Spanish Population Over 60 Years of Age
The long-chain polyunsaturated fatty acids (PUFA) of the n-3 or omega-3 series and, in particular, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), both derived from the essential fatty acid alpha-linolenic acid, are…
- Trial name
- OMEGAPRED (NCT06916455)
- Where
- Spain
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Type 2 Diabetes, Insulin Sensitivity/Resistance
Omega-3 to Reduce Diabetes Risk in Subjects With High Number of Particles That Carry "Bad Cholesterol" in the Blood
In this project, investigators explored the role of the particles that carry "bad cholesterol" in the blood (termed LDL) that are known to promote heart disease, in the promotion of type 2 diabetes (T2D) in humans.
- Conditions
- Type 2 Diabetes, Insulin Sensitivity/Resistance, Inflammatory Response, Fatty Acids, Omega-3
- Trial name
- NCT04496154
- Testing
- Omega-3 fatty acids (2.7 g/d, EPA:DHA, 2:1)
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- May Faraj, PDt, PhD
Dry Eye Syndromes, Age-Related Macular Degeneration
Efficacy of OmegaBoost to Increase Omega-3 Levels in Healthy Individuals
The purpose of this study is to determine increases in the Omega Index test indicating optimal Omega-3s particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) levels for overall systemic benefits including…
- Conditions
- Dry Eye Syndromes, Age-Related Macular Degeneration, Omega 3 Index
- Trial name
- NCT05763940
- Testing
- OmegaBoost, Nature Made (soft gel), Nature Made (gummy)
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Western University of Health Sciences
Cholesterol, Triglycerides
AlmegaPL CV Health Open Label Study
The aim of this study is to assess the effectiveness of Almega PL, a Nannochloropsis algae-derived extract rich in eicosapentaenoic acid (EPA), on improving blood markers associated with heart health of iwi customers.
- Conditions
- Cholesterol, Triglycerides, Omega-3, Eicosapentaenoic Acid
- Trial name
- NCT05267301
- Testing
- AlmegaPL (FDA NDIN # 826)
- Where
- 2 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Qualitas Health
Menopausal Patients, Chronic Periodontitis
Treatment of Periodontitis in Menopausal Patients
The goal of this clinical trial is to compare the effectiveness of polyunsaturated fatty acids (PUFAs) [omega-3] as an adjunctive treatment to scaling and root planing for menopausal women with periodontitis versus scaling and…
- Conditions
- Menopausal Patients, Chronic Periodontitis, Omega 3 Fatty Acids
- Trial name
- NCT06254118
- Testing
- Polyunsaturated Fatty Acids, olive oil
- Where
- Saudi Arabia
- Volunteers
- 20 people
- Sponsor
- Hadir F. El-Dessouky
Optimal Gastrointestinal Absorption of Omega-3
A Study to Determine Optimal Absorption of Single Dose Omega-3
This is a randomised three-way cross over study comparing the optimal absorption of a single dose of fish oil using 3 different forms to one another on increasing blood concentrations of fatty acids in 24 healthy adult…
- Trial name
- NCT05491759
- Testing
- Product 1 - AquaCelle Fish Oil Triglyceride, Product 2 - AquaCelle Fish Oil Ethyl Ester, Product 3 - Standard Fish Oil Triglyceride
- Where
- Australia
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- RDC Clinical Pty Ltd
Major Depressive Disorder, Bipolar Disorder
Multi-factor Model Constraction for Early Warning and Diagnosis of MDD
Current research on the pathogenesis of depression shows that imbalanced inflammatory factors are closely related to Major Depressive Disorder(MDD).
- Conditions
- Major Depressive Disorder, Bipolar Disorder, Omega-3 Fatty Acids
- Trial name
- NCT05529576
- Testing
- Omega 3 fatty acid
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Migraine, Omega-3 Polyunsaturated Fatty Acids
Omega-3 Fatty Acid in the Prevention of Migraine
To understand the clinical efficacy for omega-3 PUFAs migraine prevention.To uncover the underlying biochemical or neurophysiological mechanisms by which omega-3 PUFAs for migraine prevention.
- Trial name
- NCT04572789
- Testing
- Omega-3 polyunsaturated fatty acids, omega-6 PUFAs
- Where
- Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Kuang Tien General Hospital