Clinical trials: Omega-3 Fatty Acids
Fatty Acids, Omega-3, Fish Oils
Metabolic Impact of VLCPUFA-Rich Fish Oil: A Clinical Study on Omega-3 Index Enhancement in Healthy Individuals
Background: Fish oils contain omega-3 fatty acids that play important roles in the body. Researchers are studying a new type of fish oil that contains very-long-chain omega-3 fatty acids (VLCPUFAs).
- Trial name
- NCT07882160
- Testing
- VLCPUFA-rich fish oil, DHA-rich fish oil
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Omega-3 Fatty Acids, Absorption of Omega-3
Study of Metabolic Absorption Rates of DHA-Taurine as a Source of Omega-3 Fatty Acids
Omega-3 fatty acids such as docosahexaenoic acid (DHA) have well-established health benefits and are widely used to improve cardiometabolic health.
- Conditions
- Omega-3 Fatty Acids, Absorption of Omega-3, Pharmacokinetics
- Trial name
- SMART (NCT07771309)
- Testing
- DHA-taurine, DHA ethyl ester
- Where
- Denmark
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Lipid Metabolism, Omega-3 Polyunsaturated Fatty Acids
Novel Approach to Increase EPA and DHA Levels
The goal of this intervention trial is to evaluate whether combining meldonium therapy with PUFAs (polyunsaturated fatty acids) supplements containing eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) changes the plasma…
- Conditions
- Lipid Metabolism, Omega-3 Polyunsaturated Fatty Acids, Supplementation
- Trial name
- NCT07304921
- Testing
- Meldonium + PUFA, PUFA + meldonium, PUFA supplementation only
- Where
- Latvia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Riga Stradins University
Omega-3 Fatty Acids, Socket Preservation
Evaluation of OMEGA-3 Effect in Alveolar Socket Preservation in Aesthetic Zone
To evaluate the effect of Omega-3 in preserving bone after extraction
- Conditions
- Omega-3 Fatty Acids, Socket Preservation, Esthetic Zone
- Trial name
- NCT07665918
- Testing
- Omega 3 Fish Oil supplements
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Subconcussive Head Impact, Omega-3 Fatty Acids
Omega-3 Fatty Acids and Subconcussive Head Impacts
The purpose of the proposed double-blind, randomized placebo-controlled trial is to understand how supplementation with fish oil [docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA)] promote brain health against soccer…
- Trial name
- NCT06736925
- Testing
- Omega-3 Fatty Acids (EPA plus DHA), Organic soybean oil, Soccer Heading Model
- Where
- United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Indiana University
Omega-3 Fatty Acids
Can People Achieve a Target Omega-3 Index by Following a Personalized Omega-3 Dosing Regimen?
The goal of this project is to evaluate the efficacy of personalized dosage recommendations of Parasol Omega-3 Fish Oil on achieving an Omega-3 Index of >8% in individuals with a baseline Omega-3 Index <8% over a 90-day period.
- Trial name
- NCT07480707
- Testing
- Fish Oil Supplementation
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Fatty Acid Research Institute
Type 2 Diabetes, Inflammation
Targeting Risk Factors for Diabetes in Subjects With Normal Blood Cholesterol Using Omega-3 Fatty Acids
Every 3 minutes a new case of diabetes is diagnosed in Canada, mostly type 2 diabetes (T2D) increasing the risk for heart disease.
- Conditions
- Type 2 Diabetes, Inflammation, Insulin Sensitivity/Resistance, Fatty Acids, Omega-3
- Trial name
- NCT04485871
- Testing
- Omega-3 fatty acids
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Institut de Recherches Cliniques de Montreal
Cognitive Dysfunction, Alzheimer Disease
ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults
This randomized, double-blind, placebo-controlled pilot trial will evaluate the effects of alpha-linolenic acid (ALA) supplementation on cognitive function, blood-brain barrier integrity, and brain vascular health in older adults…
- Conditions
- Cognitive Dysfunction, Alzheimer Disease, Blood-Brain Barrier, Apolipoprotein E, Deficiency or Defect of
- Trial name
- NCT07392723
- Testing
- Alpha-Linolenic Acid (2.6 g/day)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Michal Schnaider Beeri, Ph.D.
Cardiovascular (CV) Risk, Atheroscleroses
Exploring Sustainable Alternatives to Marine Oils With Echium and Ahiflower Oils
This randomized, single-blind, crossover clinical trial aims to evaluate Echium oil and Ahiflower® oil as sustainable, plant-based alternatives to marine oils for omega-3 supplementation.
- Conditions
- Cardiovascular (CV) Risk, Atheroscleroses, Inflamation, Omega 3 Fatty Acids
- Trial name
- NCT07289919
- Testing
- Echium oil, Ahiflower oil, EPA capsules
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Heart Health Markers, Cardiovascular Diseases
Omega-3D: Omega-3 for Diet-Driven Health Disparities
The goal of this clinical trial is to learn whether omega-3 fatty acid supplementation can reduce inflammation-related biomarkers and improve cardiovascular health in healthy adult volunteers with different genetic backgrounds.
- Conditions
- Heart Health Markers, Cardiovascular Diseases, Omega 3 Fatty Acids
- Trial name
- NCT07078344
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Omega 3 Fatty Acids
The Impact of Pastured Livestock Food Consumption on Fatty Acid and Metabolomic Profiles
The goal of this clinical trial is to evaluate the effects of consuming meat and eggs from regenerative/pastured versus conventional farming practices on health biomarkers in middle-aged adults.
- Trial name
- NCT06768775
- Testing
- Pastured Livestock Diet, Conventional Livestock Diet
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Utah State University
Nutrition, Absorption, Metabolism and Excretion in Healthy Volunteers
Bioavailability of Omega-3 Fatty Acids From Fish Oil Supplements
This study is investigating whether a new type of fish oil supplement, in the form of soft chews, leads to better absorption of omega-3s in the body compared to traditional fish oil capsules.
- Conditions
- Nutrition, Absorption, Metabolism and Excretion in Healthy Volunteers, Fish Oils, Omega 3 Fatty Acids
- Trial name
- Ocean's O3 (NCT06665464)
- Testing
- Fish oil supplement 1, Fish oil supplement 2
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Wageningen University and Research
Fatty Acids, Omega-3
Evaluation of the Nutritional Status of Omega-3 Fatty Acids and the Possible Influences of Dietary Patterns and Different Socioeconomic Factors, in a Spanish Population Over 60 Years of Age
The long-chain polyunsaturated fatty acids (PUFA) of the n-3 or omega-3 series and, in particular, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), both derived from the essential fatty acid alpha-linolenic acid, are…
- Trial name
- OMEGAPRED (NCT06916455)
- Where
- Spain
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Type 2 Diabetes, Insulin Sensitivity/Resistance
Omega-3 to Reduce Diabetes Risk in Subjects With High Number of Particles That Carry "Bad Cholesterol" in the Blood
In this project, investigators explored the role of the particles that carry "bad cholesterol" in the blood (termed LDL) that are known to promote heart disease, in the promotion of type 2 diabetes (T2D) in humans.
- Conditions
- Type 2 Diabetes, Insulin Sensitivity/Resistance, Inflammatory Response, Fatty Acids, Omega-3
- Trial name
- NCT04496154
- Testing
- Omega-3 fatty acids (2.7 g/d, EPA:DHA, 2:1)
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- May Faraj, PDt, PhD
Major Depressive Disorder, Bipolar Disorder
Multi-factor Model Constraction for Early Warning and Diagnosis of MDD
Current research on the pathogenesis of depression shows that imbalanced inflammatory factors are closely related to Major Depressive Disorder(MDD).
- Conditions
- Major Depressive Disorder, Bipolar Disorder, Omega-3 Fatty Acids
- Trial name
- NCT05529576
- Testing
- Omega 3 fatty acid
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Migraine, Omega-3 Polyunsaturated Fatty Acids
Omega-3 Fatty Acid in the Prevention of Migraine
To understand the clinical efficacy for omega-3 PUFAs migraine prevention.To uncover the underlying biochemical or neurophysiological mechanisms by which omega-3 PUFAs for migraine prevention.
- Trial name
- NCT04572789
- Testing
- Omega-3 polyunsaturated fatty acids, omega-6 PUFAs
- Where
- Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Kuang Tien General Hospital
Omega-3 Fatty Acids, Lipid Peroxidation
Effect of High Omega-3 Fish Intake on Lipid Peroxidation
The overall goal of this project is to identify an appropriate level of high omega-3 fish (salmon) consumption that will promote optimal omega 3 nutritional status without increasing the level of lipid oxidation in the body.
- Trial name
- NCT01183520
- Testing
- Omega-3 fish oil provided by salmon
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Human Nutrition, Omega-3 Fatty Acids, Microalgae, Micronutrients
"Health Promoting Effects of the Microalgae Phaeodactylum Tricornutum"
The aim of the research project is to investigate the uptake of omega-3 fatty acids into the blood plasma through the consumption of the microalgae Phaeodactylum tricornutum (PT) in a human study.
- Trial name
- UniHoh-Algen (NCT04288544)
- Testing
- Microalgae, Omega-3-fatty acid capsule, sea fish
- Where
- 2 sites in Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Hohenheim
Nutrition, Fatty Acids, Omega-3
Ranger Resilience and Improved Performance on Phospholipid Bound Omega-3's
The goal of this study is to determine if supplementation with krill oil concentrate containing the phospholipid-bound omega-3 fatty acids improves performance on specific cognitive tests that underlie key elements in U.S.
- Conditions
- Nutrition, Fatty Acids, Omega-3, Cognition, Resilience, Psychological
- Trial name
- RRIPP-3 (NCT02908932)
- Testing
- Phospholipid-bound omega-3 supplement
- Where
- 3 sites in United States
- Volunteers
- 555 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Complementary Feeding Recommendation, Linear Programming,
Effect of Enhanced Counseling Using Complementary Feeding Recommendation Based on Linear Programming on Nutritional Status,Omega-3 Fatty Acids, Malondialdehyde, and Alpha-Tocopherol in Overweight Children in East Jakarta
The epidemic of pediatric obesity has become a public health burden in both developed and developing countries, due to its serious health consequences, including an increased risk of type 2 Diabetes Mellitus and heart disease.
- Conditions
- Complementary Feeding Recommendation, Linear Programming,, Nutritional Status, Omega-3 Fatty Acids
- Trial name
- NCT02592109
- Testing
- Enhanced Counseling using CFR based on Linear Programming
- Where
- Indonesia
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia