Clinical trials: Oncologic
Postoperative Cough, Lung Cancer
Effect of Transcutaneous Acupoint Electrical Stimulation (TAES) on Postoperative Cough in Lung Cancer
Observation and exploration of the improvement in cough symptoms in postoperative lung cancer patients with Transcutaneous Acupoint Electrical Stimulation (TAES), the change in Cough Symptom Score (CSS) compared to baseline, the…
- Trial name
- NCT06548711
- Testing
- Transcutaneous Acupoint Electrical Stimulation (TAES)
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Kong Fanming
Ovarian Cancer, Fallopian Tube Cancer
Nudge to Gynecologic Oncology
Ovarian cancer lacks an effective screening test, and prompt treatment at diagnosis is the only way to improve outcomes. Referral to gynecologic oncology at diagnosis of adnexal mass is recommend by guidelines from every major…
- Conditions
- Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Cancer
- Trial name
- NCT06451263
- Testing
- Nudge
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Cardio-Oncology, Rehabilitation
Cardio-Oncology Rehabilitation Care Process
The objective of this observational study is to assess the outcomes of a hospital-based Cardio-Oncology Rehabilitation (CORe) program focused on exercise in cancer patients undergoing cardiotoxic treatment.
- Conditions
- Cardio-Oncology, Rehabilitation, Cardiovascular Diseases, Exercise
- Trial name
- ReCO (NCT06302634)
- Testing
- Exercise-based cardio-oncology rehabilitation
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Hospital Clinico Universitario de Santiago
Adherence, Medication
Pharmacist-led Intervention on Adherence in Patients Undergoing Treatment With an Oral Oncology Medication
Boston Medical Center provides care to cancer patients on oral cancer medications through the use of Boston Medical Center Specialty Pharmacy (BMC SP).
- Trial name
- BSPAP (NCT03104114)
- Testing
- pharmacist-intervention, Historical control
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Solid Tumor, Adult
TTX-030 in Combination With Immunotherapy and/or Chemotherapy in Subjects With Advanced Cancers
This is a phase 1/1b study of TTX-030 in combination therapy, an antibody that inhibits CD39 enzymatic activity, leading to accumulation of pro-inflammatory adenosine triphosphate (ATP) and reduction of immunosuppressive…
- Trial name
- NCT04306900
- Testing
- TTX-030, budigalimab and mFOLFOX6, TTX-030, budigalimab and docetaxel, TTX-030 and mFOLFOX6
- Where
- 32 sites in United States, South Korea
- Volunteers
- 185 people
- Sponsor
- Trishula Therapeutics, Inc.
Lung Cancer
Connect Oncology Needs Evaluation Tool
The purpose of this research study is to evaluate a technology-based intervention, Caregiver Oncology Needs Evaluation Tool (CONNECT), which may increase lung cancer caregivers' knowledge about the benefits of supportive care…
- Trial name
- CONNECT-LC (NCT03919864)
- Testing
- CONNECT Intervention, CONTROL Group
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Wake Forest University Health Sciences
Solid Cancers, Geriatric Assessment
Application of the sG8 Scale in Real-World Geriatric Oncology Patients
This study is a multicenter, prospective, observational study. The study included patients aged 65 and older with solid tumors requiring systemic anti-tumor therapy.
- Trial name
- NCT06939764
- Testing
- Geriatric Screening using the sG8 scale
- Volunteers
- 346 people
- Sponsor
- Sichuan Cancer Hospital and Research Institute
Lung Cancer Non-small Cell Stage IV, Squamous Cell Lung Cancer
A Study of Anti-PD-1 AK105 in Patients With Metastatic Squamous Non-small Cell Lung Cancer
This is a phase III, randomized, double-blinded, multicenter clinical study to evaluate the efficiency and safety of AK105 (Anti-PD1 antibody) plus paclitaxel and carboplatin vs placebo plus paclitaxel and carboplatin as…
- Trial name
- NCT03866993
- Testing
- AK105, Paclitaxel, Carboplatin
- Where
- 2 sites in China
- Volunteers
- 350 people
- Sponsor
- Akeso
Oncology, NSCLC Stage IV
Efficacy and Safety of Anti-PD-1/PD-L1 Treatment +/- UV1 Vaccination in Patients With Non-small Cell Lung Cancer
A Randomized, Multicenter Study Investigating Efficacy and Safety of anti-PD-1/PD-L1-treatment +/- UV1 vaccination as first line treatment in patients with inoperable advanced or metastatic non-small cell lung cancer.
- Conditions
- Oncology, NSCLC Stage IV, NSCLC, Stage III
- Trial name
- LUNGVAC (NCT05344209)
- Testing
- UV1, Sagramostim, Anti-PD-1/PD-L1 treatment
- Where
- Norway
- Volunteers
- 138 people
- Sponsor
- Vestre Viken Hospital Trust
Head and Neck Cancer
A Study of Palifermin for the Reduction of Oral Mucositis in Subjects With Locally Advanced Head and Neck Cancer Receiving Postoperative Radiotherapy
The purpose of this study is to evaluate the efficacy, safety and tolerability of palifermin on the incidence of oral mucositis in subjects with locally advanced head and neck cancer receiving postoperative radiotherapy.
- Trial name
- NCT00540332
- Testing
- palifermin
- Sponsor
- Swedish Orphan Biovitrum
Oncology
Remote Education Strategies Training Oncology Residents for End-of-Life Discussions
Difficult conversations are common in oncology practice and patient-centered communication is essential to care for individuals with cancer.
- Trial name
- RESTORED (NCT05810987)
- Testing
- RESTORE, Medical Interaction and Coaching
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- McMaster University
Low Back Pain, Oncology
Digital Intervention for the Modification of Lifestyles (iGame)
The objective of the project is to analyze the clinical effectiveness of a gamifield mHealth application (iGAME) and developed in the context of lifestyle modification, but with the approach of the Behaviour Change Technique…
- Conditions
- Low Back Pain, Oncology, Depression, Sedentary Lifestyle
- Trial name
- NCT04019119
- Testing
- Digital intervention
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- University of Malaga
Colorectal Cancer
PACCE: Panitumumab Advanced Colorectal Cancer Evaluation Study
The purpose of this study is to assess whether treatment with the study drug, panitumumab given concomitantly with every 2 (Q2) week oxaliplatin-based chemotherapy and bevacizumab improves progression-free survival (PFS) compared…
- Trial name
- NCT00115765
- Testing
- Oxaliplatin Based Chemotherapy, Panitumumab, Irinotecan Based Chemotherapy
- Volunteers
- 1,053 people
- Sponsor
- Amgen
Pitfalls of PET Scan on Pediattic
Normal Variants and Pitfalls of 18F_FDG PET/CT in Pediatric Oncology
Detection Normal variants and pitfalls of 18_F _FDG PET/CT imaging in pediatic oncology.
- Trial name
- NCT06612567
- Testing
- PET/CT
- Volunteers
- 120 people
- Sponsor
- Assiut University
Bone Neoplasms, Soft Tissue Neoplasms
Stress and Anxiety Before Biopsy, After Biopsy Results, and During Treatment in Patients With Suspected Bone or Soft Tissue Cancer
This prospective observational study will follow adults who are scheduled for a clinically indicated biopsy because of a suspected solid tumor involving bone or soft tissue.
- Conditions
- Bone Neoplasms, Soft Tissue Neoplasms, Anxiety, Stress, Psychological
- Trial name
- BIOPSY-STRESS (NCT07727434)
- Testing
- Routine Diagnostic and Treatment Pathway
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul University
Financial Stress, Oncology Patients
Oncology Legal Navigation Study
The overall objective of this study is to implement a sustainable oncology legal navigation program that will provide direct legal navigation services to help patients and caregivers overcome legal barriers to care in order to…
- Trial name
- NCT07443839
- Testing
- oncology legal navigation services
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Jean Edward
Oncology, Extravasation
ivWatch in Prevention of Extravasation of Vesicants in an Oncology Setting
This study aims to determine the feasibility of using the ivWatch (registered trademark) device to determine if there is an infiltration at the site of a peripheral intravenous (PIV) catheter.
- Trial name
- NCT06758011
- Testing
- ivWatch
- Where
- United States
- Volunteers
- 2,400 people
- Sponsor
- Roswell Park Cancer Institute
Postoperative Pain
On-Q Pump vs Epidural for Postoperative Pain Control in Children
Open abdominal and pelvic surgery or thoracotomy (open chest surgery) is frequently performed for tumor excision in children. Post-operative pain management regimens are often at the discretions of the attending surgeon and may…
- Trial name
- NCT03496259
- Testing
- On-Q pump, Epidural catheter
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Baylor College of Medicine
Lung Cancer, Carcinoma, Non-Small-Cell Lung
Prospective, Longitudinal Biocollection in Thoracic Oncology, Including Newly Diagnosed Lung Cancer Patients
In clinical trials, patients are selected according to strict eligibility criteria (inclusion and exclusion criteria). These criteria aim to ensure homogeneity within the trial population, but may omit patients with specific…
- Conditions
- Lung Cancer, Carcinoma, Non-Small-Cell Lung, Small Cell Lung Carcinoma, Metastatic Lung Cancer
- Trial name
- BREATHE (NCT06481813)
- Testing
- Blood Sampling (2*8mL Tubes), PBMC Sampling (1*8mL Tubes), Paxgene Sampling
- Where
- 4 sites in France
- Volunteers
- 730 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Catheter Blockage, Oncology
A Novel Ureteric Stent in Kidney Stone Patients and Oncology Patients Compared to a Conventional JJ Stent
Urological stents and catheters often lead to inflammation, causing pain and infection in the urinary tract. Moreover, 80% of stents are associated with pain, negatively impacting on QoL and mental health.
- Conditions
- Catheter Blockage, Oncology, Kidney Stone
- Trial name
- CASSETTE (NCT06815120)
- Testing
- Experimental ureteric stent with specially shaped side-holes that prevent stagnation points (i.e., areas of low flow that cause particles to settle and E&B), Qualitative interview
- Where
- 2 sites in United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Southampton
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