Clinical trials: Oncologic Patients
Merkel Cell Carcinoma, Cutaneous Squamous Cell Carcinoma
Immunotherapy With IFx-Hu2.0 Vaccine for Advanced Non-melanoma Skin Cancers
In this clinical phase I, non-randomized, open-label, uncontrolled, interventional, multi-center trial, 20 adult subjects (≥ 18 years of age) with advanced non-melanoma skin cancers will receive a fixed dose of 0.1 mg of…
- Conditions
- Merkel Cell Carcinoma, Cutaneous Squamous Cell Carcinoma, Non-Melanoma Skin Cancers
- Trial name
- NCT04160065
- Testing
- IFx-Hu2.0
- Where
- 4 sites in United States
- Volunteers
- 23 people
- Sponsor
- TuHURA Biosciences, Inc.
Solid Tumor
PICC-ports Versus Chest - Ports for Long Term Chemotherapy Deliverance in Oncology Patients
Central venous access devices are extensively used in oncology patients. The current standard is represented by devices inserted by direct ultrasound guided cannulation of deep veins of supra/infraclavicular area with a reservoir…
- Trial name
- PICCHEST (NCT06541301)
- Testing
- PICC-port, Chest-port
- Where
- 3 sites in Italy
- Volunteers
- 852 people
- Sponsor
- European Institute of Oncology
Acute Myeloid Leukemia
Phase I/II Trial of S65487 Plus Azacitidine in Acute Myeloid Leukemia
The purpose of this study is to assess the safety, tolerability and clinical activity of the combination S65487 with azacitidine in patients with acute myeloid leukaemia.
- Trial name
- NCT04742101
- Testing
- S65487 and azacitidine
- Where
- 11 sites in France, Hungary and 4 more
- Volunteers
- 57 people
- Sponsor
- Institut de Recherches Internationales Servier
Radiotherapy, Inflamation
Effects of Moderate-intensity Interval Aerobic Exercise (MIIAE) on Inflammatory, Immune, Metabolic, Physical Fitness, and Quality of Life Parameters in Breast Cancer Patients Undergoing Radiotherapy.
Breast cancer and its treatment with radiotherapy may be associated with systemic inflammatory, hematological, cardiac, body composition, functional and quality-of-life alterations.
- Conditions
- Radiotherapy, Inflamation, Immune System, Physical Fitness
- Trial name
- NCT07583719
- Testing
- Moderate-Intensity Interval Aerobic Exercise
- Volunteers
- 40 people
- Sponsor
- Universidad Francisco de Vitoria
Oncologic High-risk Surgery
Measurement of Cardiac Index Using an Implanted Central Venous Access Port in Patients Scheduled for Oncologic High-risk Surgery
Perioperative hemodynamic optimization requires monitoring adapted to the risks of the surgery and the patient. We currently use a local hemodynamic protocol based on the data of the literature.
- Trial name
- ThermoD-PAC (NCT02063009)
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Well-being
Body Scan Meditations to Support Well-Being in Patients at Antwerp University Hospital.
INWARD is a pilot study designed to explore whether audio-guided body scan meditations can support well-being in adult patients receiving care in the haematology and oncology departments, including the day hospital, at Antwerp…
- Trial name
- INWARD (NCT07834021)
- Testing
- INWARD audio-guided body scan meditations
- Where
- Belgium
- Volunteers
- 29 people
- Sponsor
- Universiteit Antwerpen
Carcinoma of Unknown Primary
Gemcitabine, Docetaxel, and Capecitabine in Treating Patients With Cancer of Unknown Primary Origin
RATIONALE: Drugs used in chemotherapy, such as gemcitabine, docetaxel, and capecitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00119314
- Testing
- capecitabine, docetaxel, gemcitabine hydrochloride
- Where
- 6 sites in United States
- Sponsor
- University of Medicine and Dentistry of New Jersey
Head and Neck Neoplasms
Effectiveness of Manual Acupuncture for Head and Neck Cancer Patients Undergoing Chemoradiation
The goal of this clinical trial is to assess whether manual acupuncture (MA) is more effective than sham acupuncture in improving leukocyte count and reducing cancer-related fatigue (CRF) in head and neck cancer (HNC) patients…
- Trial name
- NCT07044414
- Testing
- Manual Acupuncture
- Where
- Indonesia
- Volunteers
- 34 people
- Sponsor
- Universitas Indonesia
Cancer Patients in Different Stages
How to Carry on an Effective Community Program of Exercice-oncology.
Exercise-oncology is an emerging area, but exist a lack of information about an effective methodology to establish counseling programs long-lasting and not based on research objectives.
- Trial name
- NCT05078216
- Testing
- Physical exercise intervention
- Where
- Spain
- Volunteers
- 405 people
- Sponsor
- Asociación Española contra el Cáncer
Blood Transfusion
Machine Learning for Transfusion Prediction in Oncologic Surgery
This study aims to use artificial intelligence to predict intraoperative bleeding and blood loss in advance for oncologic surgeries with high bleeding risk.
- Trial name
- NCT07875114
- Where
- Turkey (Türkiye)
- Volunteers
- 950 people
- Sponsor
- Kocaeli City Hospital
Lobular Carcinoma, Breast Cancer
[68]GA-FAPI-46 PET/CT for the Diagnosis of Metastatic Lesions in Patients With Lobular Breast Cancer (ICL).
Invasive squamous cell carcinoma (ISCC) represents 5 to 15% of breast cancers. Despite the rarity of this pathology, the number of patients with Invasive squamous cell carcinoma treated at HCL is significant.
- Trial name
- FAPI-CL (NCT07313033)
- Testing
- [68]GA-FAPI-46 PET scan
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Hospices Civils de Lyon
Peripheral T-cell Lymphoma
Comprehensive Oncology Measures for Peripheral T-cell Lymphoma Treatment Registry
Prospective, longitudinal, multinational, observational study that will collect data on how patients with peripheral T-cell lymphoma (PTCL) are treated in academic and community practices.
- Trial name
- COMPLETE (NCT01110733)
- Where
- 68 sites in United States
- Volunteers
- 3,000 people
- Sponsor
- Acrotech Biopharma Inc.
Oncology
Pretreatment Quality of Life as a Predictor of Distant Metastasis-Free Survival and Overall Survival in Patients With Head and Neck Cancer
This study shed light on an under-researched area by examining the prognostic associations of pre-treatment QoL with overall survival and distant metastasis free survival among patients with head and neck cancer who underwent…
- Trial name
- NCT03290352
- Testing
- Questionnaire
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Oncologic Disorders
Effect of Warm Water Footbaths With Added Ginger or Mustard Powder on Psychosocial Parameters in Patients With an Oncological Disease
A randomized, controlled, three-arm trial to investigate the effects of warm water footbaths with and without the addition of ginger or mustard powder on psychosocial parameters in patients with an oncological disease and in…
- Trial name
- NCT04271670
- Testing
- Ginger powder footbaths, Mustard powder footbaths, Warm water only footbaths
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- ARCIM Institute Academic Research in Complementary and Integrative Medicine
Barrett's Esophagus With or Without Dysplasia, Barrett Esophagus Adenocarcinoma
Development of Fluorescent Lectin Tracers With Dedicated Technology for in Vivo Detection of Esophageal Dysplasia in Barrett Patients
The goal of this clinical trial is to evaluate the feasibility of WGA-800CW with dedicated imaging systems for detection of invisible esophageal dysplasia in patients with Barrett's esophagus.
- Trial name
- GRAIN (NCT07643727)
- Testing
- WGA-800CW
- Where
- Netherlands
- Volunteers
- 49 people
- Sponsor
- University Medical Center Groningen
Cancer
mychoiceTM Implementation With Medical Oncology Patients
This is a pragmatic, non-randomized mixed-methods evaluation study designed to evaluate the feasibility and acceptability of delivering the mychoiceTM tool to new Medical Oncology patients as well as to more deeply explore its…
- Trial name
- NCT06222242
- Testing
- mychoiceTM
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Fox Chase Cancer Center
Cancer, Oncology
PACOME (PAtient Cancer Oral MEdication) Cohort of Patients Treated With Oral Anticancer Drugs Benefiting From Oncoral Multidisciplinary Monitoring in Real Life: Predictive Factors and Safety of Treatments
With the shift to ambulatory care and the rise of ATCO oral anticancer drugs, a growing number of cancer patients are benefiting from oral treatment in an outpatient setting, which meets their needs and preference over injectable…
- Conditions
- Cancer, Oncology, Oncoral Program
- Trial name
- PACOME (NCT06317389)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 3,000 people
- Sponsor
- Hospices Civils de Lyon
Non Small Cell Lung Cancer
Study to Assess the Effect of Rifampicin on Blood Levels and Safety of AZD9291, in Patients With EGFRm+ NSCLC
This is a Phase I, open-label, 2-part study in patients with a confirmed diagnosis of epidermal growth factor receptor (EGFR) mutation positive (EGFRm+) non-small cell lung cancer (NSCLC), who have progressed following prior…
- Trial name
- NCT02197247
- Testing
- Pharmacokinetic sampling - AZD9291, Rifampicin, AZD9291 tablet dosing
- Where
- 18 sites in United States, Netherlands and 4 more
- Volunteers
- 41 people
- Sponsor
- AstraZeneca
Breast Cancer, Endometrial Cancer
A Study of LY353381 (Arzoxifene) for Patients Who Benefitted From This Drug in Other Oncology Trials and Wished to Continue Treatment
Patients who were previously enrolled on the LY353381 arm of any LY353381 oncology trial could enroll in this "roll-over" study if they had exhibited clinical benefit from treatment and wished to continue on treatment.
- Conditions
- Breast Cancer, Endometrial Cancer, Ovarian Cancer
- Trial name
- NCT00190697
- Testing
- arzoxifene
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Eli Lilly and Company
Breast Cancer
Effects of an ICT-platform for Assessment and Management of Patient-reported Symptoms During Treatment for Breast Cancer
The purpose of this study is to evaluate the effects of an interactive Information and Communication Technologies (ICT) -platform for use in a smartphone or tablet in patients treated with neoadjuvant chemotherapy for breast…
- Trial name
- PhONEME (NCT02479607)
- Testing
- Smartphone or tablet
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Karolinska Institutet
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