Clinical trials: Oncologic Patients
Oncology
Quality of Life Assessment for Early Identification of Supportive Care Needs in Oncology Patients
The aim of this study is to evaluate the value of the nurse's use of the Quality of Life (QoL) scores of the European Organisation for Research and Treatment of Cancer [EORTC] Quality of Life Questionnaire [QLQ] C30 as an aid in…
- Trial name
- SOS-DETEQT (NCT06337487)
- Testing
- QoL questionnaires, Qualitative Interview (for one part of nurses only), ORIC questionnaire
- Where
- 2 sites in France
- Volunteers
- 93 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Lymphoma, Childhood Lymphoma
Study of Genistein in Pediatric Oncology Patients (UVA-Gen001)
Toxicities related to pediatric cancer treatment can lead to significant illness, organ damage, treatment delays, increased health care cost, and decrease in quality of life.
- Conditions
- Lymphoma, Childhood Lymphoma, Solid Tumor, Childhood Solid Tumor
- Trial name
- UVA-Gen001 (NCT02624388)
- Testing
- Genistein
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Virginia
Pediatric Cancer, Cancer Survivor
LOG-I - Impact Study of LOG-AFTER Software on Long-term Monitoring of Former Patients (LOG-I - LOG-Impact Study)
Childhood cancer survivors represent a high-risk population that requires risk-based follow-up. Follow-up recommendations have been harmonized.
- Conditions
- Pediatric Cancer, Cancer Survivor, Hemato-oncologic Patients
- Trial name
- LOG-I (NCT06939322)
- Testing
- Use of the Log-AFTER software
- Where
- France
- Volunteers
- 320 people
- Sponsor
- University Hospital, Angers
Spine Tumor, Vertebral Metastasis
MOVEMENT ANALYSIS IN PATIENTS UNDERGOING VERTEBRECTOMIES FOR SPINE ONCOLOGY: A PILOT STUDY
Analyze the geometric and kinematic parameters of the spine in patients undergoing vertebrectomy through gait analysis, both during the execution of motor tasks such as walking, standing, and basic trunk movements, with the aim…
- Conditions
- Spine Tumor, Vertebral Metastasis, Vertebral Column Mass
- Trial name
- NCT07326969
- Testing
- vertebrectomy
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Istituto Ortopedico Rizzoli
COVID-19 Infection, Hematopoietic and Lymphoid Cell Neoplasm
Effect of the COVID-19 Public Health Crisis on the Mental Health and Physical Well-Being of Cancer Patients, the Coping With COVID Study
This study determines how the threat of the coronavirus has affected the mental health and physical well-being of cancer patients seen at the psychiatric oncology clinic, and how they have coped with any related stress.
- Conditions
- COVID-19 Infection, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT04652505
- Testing
- Questionnaire Administration
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- M.D. Anderson Cancer Center
Nausea, Vomiting and Anxiety Associated With Medical Oncology Patients
The Use of Aromatherapy for Symptom Management
The purpose of this pilot study is to introduce the use of aromatherapy/essential oils to medical oncology patients at Central DuPage Hospital to assess their perceived effectiveness to relieve symptoms of nausea or vomiting…
- Trial name
- NCT02163369
- Testing
- Peppermint and Lavender Essential Oils
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Central DuPage Hospital
Oncology
Potential of Moderate Whole Body Hyperthermia to Enhance Response
Using moderate whole-body hyperthermia (mWBH) in tumor patients to see the influence on circulating tumor cells, tumor response, quality of life, fatigue, psyche, immune response and tumor microenvironment
- Trial name
- POWER (NCT05821166)
- Testing
- moderate Whole Body Hyperthermia (mWBH)
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Charite University, Berlin, Germany
Caregiver Burden, Care Giving Burden
Online Educational Tool for Caregivers of Pediatric Oncology Patients
The goal of this study is to assess the feasibility of using a game-based tool for caregivers of pediatric oncology patients to increase caregiver knowledge about supportive care for oncology patients while simultaneously…
- Conditions
- Caregiver Burden, Care Giving Burden, Pediatric Cancer
- Trial name
- NCT05616572
- Testing
- OncoWhiz
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Washington University School of Medicine
Neoplasms (Cancer / Tumors), Geriatric Oncology
Optimising the Cancer Management of Older Patients by Early and Specific Geriatric Interventions.
The WARNING project proposes a new care organisation for older patients with cancer. The aim is to optimise management in daycare with early detection signs of geriatric syndromes and specific interventions.
- Trial name
- WARNING (NCT07704307)
- Testing
- WARNING Pack
- Volunteers
- 1,010 people
- Sponsor
- Poitiers University Hospital
Solid Tumours
Study to Assess the Blood Levels and Safety of Olaparib in Patients With Advanced Solid Tumours and Normal or Impaired Kidney Function
This is a 2-part study in patients with advanced solid tumours. Part A will investigate the PK of olaparib in patients with mild or moderate renal impairment compared to patients with normal renal function; Part B will allow…
- Trial name
- NCT01894256
- Testing
- Olaparib tablet dosing
- Where
- 13 sites in Belgium, Denmark and 3 more
- Volunteers
- 56 people
- Sponsor
- AstraZeneca
Liver Cancer, Anxiety Disorder
Early Palliative Care With Standard Care or Standard Care Alone in Improving Quality of Life of Patients With Incurable Lung or Non-colorectal Gastrointestinal Cancer and Their Family Caregivers
The study intervention consists of the early integration of palliative care services into standard oncology care in an outpatient setting for patients with advanced lung and non-colorectal gastrointestinal malignancies who are…
- Conditions
- Liver Cancer, Anxiety Disorder, Depression, Small Cell Lung Cancer
- Trial name
- NCT02349412
- Testing
- Early palliative care
- Where
- 23 sites in United States
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- Alliance for Clinical Trials in Oncology
Esophageal Cancer, Gastric Cancer
Sarcopenia and Visceral Obesity in Esophageal and Gastric Cancer
In line with improvements in oncologic outcome for patients with esophageal cancer, the attritional impact of curative treatment with respect to functional status and health-related quality of life (HR-QL) in survivorship is…
- Conditions
- Esophageal Cancer, Gastric Cancer, Sarcopenia, Sarcopenic Obesity
- Trial name
- NCT03061370
- Testing
- Esophagectomy or Gastrectomy
- Where
- 2 sites in Ireland
- Volunteers
- 317 people
- Sponsor
- St. James's Hospital, Ireland
Solid Tumors, Urothelial Carcinoma
A Study Evaluating MM-310 in Patients With Solid Tumors
MM-310 is a liposomal formulation of a docetaxel prodrug that targets the EphA2 receptor on cancer cells. Docetaxel is an approved chemotherapeutic drug.This study is a Phase 1 open-label study of MM-310 in patients with solid…
- Conditions
- Solid Tumors, Urothelial Carcinoma, Gastric Carcinoma, Squamous Cell Carcinoma of the Head and Neck
- Trial name
- NCT03076372
- Testing
- MM-310
- Where
- 5 sites in United States
- Volunteers
- 34 people
- Sponsor
- Merrimack Pharmaceuticals
Acute Myeloid Leukemia
A Collaborative Palliative and Oncology Care Model for Patients With Acute Myeloid Leukemia
This research study is evaluating the impact a collaborative palliative care and oncology team will have on the quality of life, symptoms, mood, and end of life outcomes of patients with acute myeloid leukemia (AML).
- Trial name
- NCT02975869
- Testing
- Standard Leukemia Care, Palliative Care
- Where
- 4 sites in United States
- Volunteers
- 160 people
- Sponsor
- Massachusetts General Hospital
Breast Cancer
Physical Activity and Healthy Aging: Promoting Cardio-metabolic Capacity to Fight Chronic Inflammation and Improve Outcomes in Breast Cancer Patients (PhActHealth Study)
PhActHealth is a multicenter randomized controlled trial enrolling women with newly diagnosed luminal B or triple-negative breast cancer (BC) who are candidates for neoadjuvant therapy.
- Trial name
- PhActHealth (NCT07776951)
- Testing
- Pre-habilitation exercise program
- Where
- 2 sites in Italy
- Volunteers
- 126 people
- Sponsor
- University of Milan
Oncology, Adverse Event
Improving Care Pathway Using Simplified Digital Tools for Oncology Patients: a Multicenter "Before-and-after" Study
Developments in the healthcare sector in general, and in oncology in particular, mean that patients are increasingly autonomous. Outpatient treatment raises the issue of home monitoring.
- Conditions
- Oncology, Adverse Event, Numeric Application, Care Telemonitoring
- Trial name
- ONCONECTSAFE (NCT05968027)
- Testing
- Nouveal numeric application "Onco'nect"
- Volunteers
- 480 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Gynecologic Cancer, Breast Cancer
Web-based Family History Tool
The purpose of this pilot study is to determine if a web-based tool that collects family health history is useful for patients being seen in a gynecologic oncology office setting.
- Conditions
- Gynecologic Cancer, Breast Cancer, BRCA1 Mutation, BRCA2 Mutation
- Trial name
- Progeny (NCT04890327)
- Testing
- Web-based family health history tool
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Psychosocial Distress, Cancer
Addressing Cancer-Related Distress Through Survivorship Care in Community Oncology
The goal of this study is to understand whether providing a structured survivorship care visit at the beginning of cancer treatment is associated with changes in distress and quality of life in adults with cancer receiving…
- Trial name
- NCT07673731
- Testing
- Structured Survivorship Visit
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Ellis Medicine
Colorectal Cancer
Phase I/Randomized Phase II Study of Second Line Therapy With Irinotecan + Cetuximab +/- RAD001 for Colorectal Cancer
The addition of RAD001, an mTOR inhibitor, to irinotecan and anti-EGFR antibody cetuximab may increase efficacy for patients with metastatic colorectal cancer who progressed on prior chemotherapy.
- Trial name
- NCT00522665
- Testing
- Irinotecan, Cetuximab, RAD001
- Where
- 14 sites in United States
- Volunteers
- 41 people
- Sponsor
- Hoosier Cancer Research Network
Lung Cancer
Evaluation of the Impact of a Coordinating Nurse in a Personalized Care Program on Quality of Care, Coordination of the Actors and on Quality of Life for Patients With Lung Cancer
The prognosis of patients with lung cancer is related to the stage of the diagnosis : 73% of one-year-survival rate at stage IA and only 13% one-year-survival rate at stage IV.
- Trial name
- EVIDEC (NCT02822209)
- Testing
- EORTC QLQ-C30, Satisfaction questionnaire - patient, Satisfaction questionnaire - general practitioner or home nurse
- Where
- France
- Volunteers
- 59 people
- Sponsor
- Groupe Hospitalier de la Region de Mulhouse et Sud Alsace
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