Clinical trials: Oncologic Patients
Soft Tissue Sarcoma Adult
Precise Local Injection of Anti-cancer Drugs Using Presage's CIVO Device in Soft Tissue Sarcoma
This is a feasibility study in patients with localized or metastatic soft tissue sarcoma undergoing surgery to determine how sarcoma in situ responds to injected microdoses of anti-cancer therapeutics.
- Trial name
- NCT03056599
- Testing
- Multiple drug microinjection, CIVO device
- Where
- 3 sites in United States
- Volunteers
- 23 people
- Sponsor
- Presage Biosciences
Family Members of: Newborns Extremely Premature, Family Members of: New Pediatric Oncology Patients
Impact of Serious Pediatric Illness on Parent and Sibling Health
To estimate the impact of having a child with serious illness (SI) on the health and healthcare of other members of the child's family.
- Conditions
- Family Members of: Newborns Extremely Premature, Family Members of: New Pediatric Oncology Patients, Family Members of: Critical Congenital Heart Defect Patients, Family Members of: Children Severe Neurological Impairment
- Trial name
- NCT03971344
- Where
- United States
- Volunteers
- 161,000 people
- Sponsor
- Children's Hospital of Philadelphia
Non-small Cell Lung Cancer, Small Cell Lung Cancer
Early Palliative Care in Advanced Lung and Gastrointestinal Malignancies
The purpose of this study is to compare two types of care - standard oncology care and standard oncology care with early palliative care (started soon after diagnosis) to see which is better for improving the experience of…
- Conditions
- Non-small Cell Lung Cancer, Small Cell Lung Cancer, Mesothelioma, Esophageal Cancer
- Trial name
- NCT01401907
- Testing
- early palliative care
- Where
- United States
- Volunteers
- 351 people
- Sponsor
- Massachusetts General Hospital
Breast Cancer
Technology and Navigation to Improve Survivorship Care
The goal of this research study to learn about breast cancer survivorship and possible ways to improve breast cancer survivorship programs using technology.
- Trial name
- NCT01663870
- Testing
- Audio Recorded Interviews, Focus Group Session, Website Session
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Frailty, Neuromuscular Blockade
Incidence of Residual Neuromuscular Blockade in Fraility in OncoGynae Surgery
Frailty among patients undergoing surgery is strongly associated with an elevated risk of adverse perioperative outcomes, heightened incidence of postoperative complications, increased mortality rates, and prolonged hospital…
- Conditions
- Frailty, Neuromuscular Blockade, General Anesthetic Drug Adverse Reaction, Gynecologic Cancer
- Trial name
- FIGO (NCT06216002)
- Testing
- Train of four nerve stimulator
- Where
- Thailand
- Volunteers
- 356 people
- Sponsor
- Mahidol University
Oncologic Diseases, Cancer
Implementation and Evaluation of a Program Aimed at Facilitating Palliative Care Conversations
Cancer is one of the leading causes of death worldwide. In the care of people with cancer, it is essential to pay sufficient attention to individual care needs and quality of life.
- Trial name
- MCMV (NCT07402057)
- Testing
- My Care My Voice Intervention
- Where
- 4 sites in Belgium
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Oncology, Acute Myeloid Leukemia
A Study of LAM-003 in Patients With Acute Myeloid Leukemia
A Phase 1 Dose-Escalation Study of LAM-003 in Patients with Acute Myeloid Leukemia
- Trial name
- NCT03426605
- Testing
- Open Label LAM-003
- Where
- 6 sites in United States
- Volunteers
- 17 people
- Sponsor
- IRulya Therapeutics Inc.
Cancer
Effectiveness, Acceptability and Feasibility of a Communication and Care Coordinator (CCC) Model in Facilitating Serious Illness Communication (SIC) and Care in Patients With Cancer
The goal of this clinical trial is to evaluate the communication and care coordinator (CCC) model in a national cancer institute and assess the utility of the model in facilitating serious illness communication (SIC) and care for…
- Trial name
- CCC-Cancer (NCT07733973)
- Testing
- CCC Intervention
- Where
- Singapore
- Volunteers
- 560 people
- Sponsor
- National Cancer Centre, Singapore
Cancer
Umbrella Study for Analysis of Data Related to Patients With Cancer
This study is a multisite, minimal risk, non-interventional study using patient electronic health record data collected as part of standard of care to answer cohort-based research questions and create robust real-world data sets.
- Trial name
- Polaris (NCT06018753)
- Where
- 10 sites in United States
- Volunteers
- 77 people
- Sponsor
- Tempus AI
Cancer
Impact of Virtual Reality on the Quality of Life of Oncology Patients
Anxiety, nausea and vomiting are common side effects in paediatric patients receiving chemotherapy. chemotherapy. New evidence supports the efficacy of immersive virtual reality in improving symptoms of anxiety and distress…
- Trial name
- VIRONSCARE (NCT06485869)
- Testing
- Measure the improvement in quality of life, Measure the level of satisfaction of patients and nursing staff, Measurement of anxiety and pain
- Where
- 2 sites in France
- Volunteers
- 150 people
- Sponsor
- Central Hospital Saint Quentin
High-Risk Neuroblastoma
Patients Between the Ages of 12 Months to 21 Years With Newly-Diagnosed High-Risk Neuroblastoma Will Receive Children's Oncology Group (COG) Type Recommended Therapy With the Addition of Naxitamab and Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) to Induction Cycles 1-5
This clinical trial will evaluate the safety of chemoimmunotherapy with Naxitamab and COG-type induction chemotherapy in newly-diagnosed patients with high-risk neuroblastoma. We aim to recruit 10 patients over the next 2 years.
- Trial name
- NCT07537400
- Testing
- Naxitamab
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Shaare Zedek Medical Center
Colonic Cancer
Colectomy for Cancer in the Elderly by Laparoscopy or Laparotomy
The purpose of this study is to compare the postoperative global morbidity between patients who have been operated on for a colon cancer by laparotomy and those operated on by laparoscopy
- Trial name
- CELL (NCT03033719)
- Testing
- Laparotomy, Laparoscopy
- Where
- France
- Volunteers
- 276 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Breast Cancer, Breast Reconstruction
Hypofractionated vs Conventional RT After Prosthetic Breast Reconstruction
This study investigates the safety and efficacy of hypofractionated radiotherapy (HFRT) versus conventional fractionated radiotherapy (CFRT) in breast cancer patients undergoing total mastectomy with prosthetic reconstruction.
- Conditions
- Breast Cancer, Breast Reconstruction, Radiation Oncology
- Trial name
- NCT07084519
- Testing
- hypofractionated radiotherapy, conventional fractionated radiotherapy
- Where
- China
- Volunteers
- 506 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Neoplasms
Pharmacokinetic Drug-Drug Interaction Study of Rucaparib
The purpose of this study is to assess pharmacokinetic concentrations of multiple probes alone followed by assessment of the same drug pharmacokinetic concentrations when the patient has steady-state exposure to rucaparib…
- Trial name
- DDI (NCT02740712)
- Testing
- Caffeine, Warfarin, Omeprazole
- Where
- 3 sites in Poland
- Volunteers
- 17 people
- Sponsor
- pharmaand GmbH
Gynecologic Cancer
Massage, Oncology, Pain, Anxiety, Feasibility
The goal of this clinical trial is to determine the feasibility of studying massage therapy in patients with gynecologic cancers while receiving infusion treatments.
- Trial name
- IMPACT (NCT07502157)
- Testing
- Massage Therapy, Attention Control
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Jill Cole
Sentinel Lymph Node Biopsy
Oncologic Safety of Sentinel Lymph Node Biopsy in Clinically Palpable Axillary Lymph Node in Breast Cancer Patients
Evaluation patients with palpable lymph node with breast cancer by sentinel lymph node biopsy and how to affect on the management of breast cancer.
- Trial name
- NCT05703295
- Testing
- Biopsy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Adverse Drug Reactions
Collection, Evaluation and Assessment of Adverse Drug Reactions on the Oncology Ward
The proposed cohort study collected within a 5-month observation period adverse drug reaction (Adverse Drug Events - ADE) in patients at the Department of Oncology at the University of Zurich.
- Trial name
- NCT01058122
- Testing
- Collection of adverse drug events
- Where
- Switzerland
- Volunteers
- 129 people
- Sponsor
- University of Zurich
BK Virus Infection
Role of Neutralizing Antibodies in the Prediction and Treatment of BK Virus Infection in Hematopoietic Stem Cell Allograft Patients at the Pediatric Oncology-hematology Department of the HUS
The BK virus (BKV) belongs to the Polyomaviridae family. The primary infection, generally asymptomatic, occurs during childhood.
- Trial name
- BKV-Allograf (NCT05618275)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Chemotherapy, Sun Protection
Effect of Gamified Sun Protection Education Provided to Chemotherapy Patients
Chemotherapy may cause photosensitivity and other skin reactions that can negatively affect patients' comfort, quality of life, and adherence to treatment.
- Conditions
- Chemotherapy, Sun Protection, Self Efficacy, Oncology Patients
- Trial name
- NCT07812532
- Testing
- Gamified education
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Lokman Hekim University
Malignant Neoplasm
Oncology Research Information Exchange Network in Improving Genetic Screening Rate in Patients With Cancer
This research trial studies how well Oncology Research Information Exchange Network (ORIEN) works in improving genetic screening rate in patients with cancer.
- Trial name
- NCT03348137
- Testing
- Questionnaire Administration
- Where
- United States
- Sponsor
- University of Southern California
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