Clinical trials: Oncological Disease
Preventive Cardiology, Respiration Disorders
"ADEN Platform: Pilot Clinical Validation for Chronic Disease Risk Stratification in Colombia"
This protocol describes a 90-day prospective pilot study designed to validate the capacity of the ADEN clinical intelligence platform to stratify early chronic disease risk across six priority public health profiles in Colombia.
- Conditions
- Preventive Cardiology, Respiration Disorders, Oncologic Disease, Autoimmune
- Trial name
- VALIDATES (NCT07727915)
- Testing
- Molecular Target
- Where
- Colombia
- Volunteers
- 120 people
- Sponsor
- Unidad de Investigación Genética Molecular
Lung Cancer
PulmoSalud: Multimodal Program for Prehabilitation and Early Home Rehabilitation in Patients With Lung Cancer
Lung cancer remains a leading cause of morbidity and mortality, and resective surgery is the treatment of choice in operable stages.
- Trial name
- NCT07478276
- Testing
- Individualized pre-operative physical exercise, Post-operative rehabilitation physical exercise, Respiratory physiotherapy Prehabilitation
- Volunteers
- 84 people
- Sponsor
- FranciscoVeraSerrano
Non-Small Cell Lung Cancer, Small Cell Lung Cancer
Multi-Indication, Retrospective Oncological Study to Validate the Accuracy in Predicting TTP by PrediCare in Patients Under SOC
This is a retrospective observational, open label study to evaluate and prospectively validate in a blind manner the accuracy of predicting treatment outcomes by PrediCare in individual patients with Non-Small Cell Lung Cancer…
- Conditions
- Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Prostate Cancer, Breast Cancer
- Trial name
- NCT02577627
- Testing
- PrediCare
- Where
- Israel
- Volunteers
- 5,000 people
- Sponsor
- Optimata Ltd.
Cervical Cancer
Surgical Staging in Cervical Cancer Prior to Chemoradiation
The aim of this study is to determine whether the modified therapy on the basis of operative staging and systematic, pelvine and paraaortal lymphadenectomy for patients with cervical cancer of the FIGO stages IIB-IV prior to…
- Trial name
- uterus11 (NCT01049100)
- Testing
- lymphadenectomy, Standard Staging
- Where
- 2 sites in Germany
- Volunteers
- 250 people
- Sponsor
- Charite University, Berlin, Germany
Non-Small-Cell Lung Cancer (NSCLC), Brain Metastasis
Hippocampal-Sparing Prophylactic Cranial Irradiation in Pathologically Nodal Positive Non-Small-Cell Lung Cancer
Background. During the clinical course of patients with locoregionally advanced non-small-cell lung cancer (LA-NSCLC) who have undergone aggressive treatment, brain metastasis (BM) is a frequent seen pattern of disease relapse…
- Trial name
- NCT02448992
- Testing
- hippocampal-sparing WBRT
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Chang Gung Memorial Hospital
Cancer, Rectum
Converted Laparoscopic Resection of Upper Rectal Carcinoma T1-4 N0-1 in Obese Patients.
Background: laparoscopic resection (LAR) is a safe approach and widely used for rectal cancer after neoadjuvant chemo-radiotherapy, but short term and oncological outcome for converted cases to open surgery (cLAR), may be…
- Trial name
- NCT04401787
- Testing
- Anterior resection for upper rectal cancer in obese
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Obesity, Colorectal Cancer
Short-term and Oncological Outcomes of Laparoscopic Colorectal Cancer Surgery in Obese Patients
A total of 138 consecutive patients who underwent laparoscopic-assisted or open colectomy for colorectal cancer (CRC) were included in the present study. Subjects commonly shared a condition of overweight or obesity.
- Trial name
- Surg_2021 (NCT04716062)
- Testing
- Open or Laparoscopic-assisted Colorectal surgery
- Where
- Italy
- Volunteers
- 138 people
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
General Surgery, Radiology
Neoadjuvant Radiotherapy Before Surgery for Rectal Cancer, Surgical and Oncological Outcome Analysis, Retrospective Case Control Study in a Single Institute.
Pre-operative radiotherapy for clinical stage 3 rectal cancer outcome analysis, retrospective case-control study.
- Trial name
- NCT06713824
- Where
- Taiwan
- Volunteers
- 1,000 people
- Sponsor
- Taichung Veterans General Hospital
Oncologic Disorders, Hematologic Diseases
Clinical Use of Pathogen Reduced Red Blood Cell Suspension
The aim of the study is to evaluate the effectiveness and safety of the application of pathogen inactivated RBC suspension in children with oncological and hematological diseases.
- Trial name
- NCT03426553
- Testing
- Riboflavin+UV RBC, irradiated RBC
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- Federal Research Institute of Pediatric Hematology, Oncology and Immunology
Blood Loss, Surgical, Blood Loss Requiring Transfusion
ROTEM-guided Transfusion Protocol in Attempt to Reduce Blood Transfusions in Major Oncological Surgery
Need for perioperative blood transfusion is still high in certain types of oncological abdominal surgery. Allogeneic blood transfusion may be detrimental in cancer patients undergoing a potentially curative resection of malignant…
- Conditions
- Blood Loss, Surgical, Blood Loss Requiring Transfusion, Coagulation Defect; Acquired
- Trial name
- ROTEM-SUR (NCT03993977)
- Testing
- Rotational thromboelastometry, Conventional treatment
- Where
- Finland
- Sponsor
- Tampere University Hospital
Breast Cancer, Comorbidities and Coexisting Conditions
Streamlined Geriatric and Oncological Evaluation Based On IC Technology
The primary objective of GERONTE STUDY is to evaluate the effectiveness of the GERONTE, ICT-based, integrated care pathway to improve patient 6-month quality of life, in France.
- Conditions
- Breast Cancer, Comorbidities and Coexisting Conditions, Lung Cancer, Colorectal Cancer
- Trial name
- FRONE (NCT05720910)
- Testing
- GERONTE
- Where
- 11 sites in France
- Volunteers
- 720 people
- Sponsor
- Institut Bergonié
Lymphedema, Pain
Innovation Oncological Rehabilitation: Applicability of the Different Techniques Physiotherapeutic Post Breast Cancer
The aim of this study is to evaluate the effects and validate news physiotherapy techniques: robotic rehabilitation, virtual reality, vibration therapy, canoeing and hand cycling in the secondary clinical complications of the…
- Trial name
- NCT03105440
- Testing
- Virtual reality, Vibration therapy, Hand cycling
- Where
- Brazil
- Volunteers
- 6 people
- Sponsor
- Universidade do Vale do Paraíba
Neoadjuvant Chemoradiotherapy, Rectal Tumor
Outcomes of Resection at Different Times Between the End of Neoadjuvant Treatment and Surgery
Neoadjuvant radio-chemotherapy (NRCT) represents a milestone in the treatment of selected rectal tumours. Ideal time interval between the end of NRCT and surgery is still debated; a 6-8 weeks time interval is considered optimal…
- Conditions
- Neoadjuvant Chemoradiotherapy, Rectal Tumor, Surgery, Surgery--Complications
- Trial name
- NCT04013347
- Testing
- Rectal Resection
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Campus Bio-Medico University
Prostate Cancer
Evaluating the Effects of Frozen Section Technology on Oncological and Functional Outcomes at Radical Prostatectomy.
In summary this trial will test whether this new surgical technique can be used to make surgery safer and more effective whilst allowing improved quality of life for patients having surgery for prostate cancer.
- Trial name
- NeuroSAFEPROOF (NCT03317990)
- Testing
- NeuroSAFE procedure, Standard RARP
- Where
- 5 sites in United Kingdom
- Volunteers
- 407 people
- Sponsor
- University College, London
Colon Neoplasms, Right Colon Tumors
Multicenter Prospective Study Protocol for Validating Surgical Quality Standards in D3 Lymphadenectomy for Oncological Right Hemicolectomy
Introduction: D3 lymphadenectomy (D3L) for right hemicolectomy, proposed by Eastern guidelines, aims to improve oncological outcomes by extending resection to include lymphatic drainage zones beyond those addressed by complete…
- Conditions
- Colon Neoplasms, Right Colon Tumors, Lymphadenectomy
- Trial name
- D3L (NCT07847216)
- Testing
- Right Colectomy & D3 Lymphadenectomy
- Volunteers
- 120 people
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears
Infection, Hospital
Passive Disinfection Cap Compliance Study
Insertion and maintenance of central venous catheter (CVC) lines are common hospital procedures in patients, including those being treated for cancer.
- Trial name
- NCT03391960
- Testing
- Passive disinfection device
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- Solventum US LLC
Sarcopenia, Pediatric Cancer
Determination of Sarcopenia Risk and Related Factors in Pediatric Oncological Patients
In children, both malnutrition and sarcopenia are associated with prolongation of hospital stay, increased morbidity, mortality, and health-related complications.
- Trial name
- NCT05294380
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Trakya University
Pain, Depression Anxiety Disorder
Hypnosis in Pain Management, Anxiety and Depression in Oncological Patients
The aim of this trial is to compare and evaluate the effects of hypnosis in cancer patients, to reduce the level of pain, anxiety and depression.
- Trial name
- HPMADOP (NCT02105740)
- Testing
- Hypnosis, Control
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Gil Montenegro
Oro-Facial-Digital Syndrome
Mindfulness and Education in Patients With Non-oncological Orofacial Pain
To analyze the effects of a program based on Mindfulness plus Pain Neurophysiology Education versus a program based on Pain Neurophysiology Education on perceived quality of life, pain, sleep quality, and functionality, in adult…
- Trial name
- NCT05732753
- Testing
- Mindfulness + Education in Neurophysiology of pain
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Jaén
Rectum Cancer
Oncological Differences Between Transanal and Laparoscopic Total Mesorectal Excision for Rectal Cancer.
The primary purpose of this study is to compare the differences of oncological in rectal cancer patients undergoing laparoscopic or transanal endoscopy radical resection.
- Trial name
- NCT05201885
- Where
- China
- Volunteers
- 192 people
- Sponsor
- Yanhong Deng