Clinical trials: Oncological Outcomes
Prostate Cancer
Oncological and Functional Outcomes After Radical Prostatectomy for Prostate Cancer: Comparing Open With Robot-assisted Surgery
For primary surgical treatment of prostate cancer the investigators compare the classic open surgery (radical retropubic prostatectomy, RRP) versus robot-assisted laparoscopic surgery (RALP).
- Trial name
- NCT01578356
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Prostate Cancer, Prostate Adenocarcinoma
Initial Experience in Brazilian Single Center With High Intensity Focalized Ultrasound (HIFU) Prostate Cancer Therapy: Morbidity, Oncological and Functional Outcomes.
Prostate cancer (PCa) is the most prevalent non cutaneous cancer in occidental countries. In Brazil incidence was about sixty thousand new cases in 2016 and occupied second place as all cancer mortality, just behind lung cancer.
- Conditions
- Prostate Cancer, Prostate Adenocarcinoma, Transrectal High Intensity Focused Ultrasound
- Trial name
- NCT03255135
- Testing
- HIFU
- Where
- Brazil
- Volunteers
- 130 people
- Sponsor
- Hospital de Transplante Doutor Euryclides de Jesus Zerbini
Rectal Neoplasms
Selection of Surgical Technique in Rectal Cancer
Currently, there is no prediction scale available to identify patients with rectal neoplasms as technically complex in the middle and lower thirds; that is, those who are at high risk of affected circumferential margins and low…
- Trial name
- TECARE (NCT06442215)
- Testing
- Data collection
- Where
- Spain
- Volunteers
- 333 people
- Sponsor
- Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
Carcinoma, Renal Cell, Pathology
Prognostic Significance of Preoperative Hemoglobin A1c (HbA1c) in Renal Cell Carcinoma
The effect of preoperative glycemic control measured by HbA1c on renal cell carcinoma (RCC) outcome remains controversial. Thus, the investigators aim to examine the association of preoperative glycemic control with oncologic…
- Conditions
- Carcinoma, Renal Cell, Pathology, Treatment Outcome, Hemoglobin A1c Protein, Human
- Trial name
- NCT02417194
- Where
- South Korea
- Volunteers
- 238 people
- Sponsor
- Seoul National University Hospital
Prostate Cancer
Evaluating the Effects of Frozen Section Technology on Oncological and Functional Outcomes at Radical Prostatectomy.
In summary this trial will test whether this new surgical technique can be used to make surgery safer and more effective whilst allowing improved quality of life for patients having surgery for prostate cancer.
- Trial name
- NeuroSAFEPROOF (NCT03317990)
- Testing
- NeuroSAFE procedure, Standard RARP
- Where
- 5 sites in United Kingdom
- Volunteers
- 407 people
- Sponsor
- University College, London
Cervical Cancers, Vaginal Cancers
Quality of Life and Sexuality After Pelvic Exenteration for Gynecologic Cancer
Pelvic exenteration is an exceptionally extensive and very rare surgical procedure, most commonly used in the treatment of locally recurrent cervical cancer among gynecological malignancies.
- Conditions
- Cervical Cancers, Vaginal Cancers, Vulvar Cancers, Endometrial Cancer
- Trial name
- NCT07594327
- Where
- Finland
- Volunteers
- 21 people
- Sponsor
- Tampere University Hospital
Renal Cell Carcinoma
Oncological and Perioperative Outcomes of Laparoscopic Versus Robotic Partial Nephrectomy for Treatment of Renal Tumors.
partial nephrectomy offers lower renal function impairment and equivalent oncological survival outcomes compared with radical nephrectomy in those with T1 tumors.
- Trial name
- NCT06424080
- Testing
- laparoscopic partial nephrectomy, robotic partial nephrectomy
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Menoufia University
Colon Neoplasms, Right Colon Tumors
Multicenter Prospective Study Protocol for Validating Surgical Quality Standards in D3 Lymphadenectomy for Oncological Right Hemicolectomy
Introduction: D3 lymphadenectomy (D3L) for right hemicolectomy, proposed by Eastern guidelines, aims to improve oncological outcomes by extending resection to include lymphatic drainage zones beyond those addressed by complete…
- Conditions
- Colon Neoplasms, Right Colon Tumors, Lymphadenectomy
- Trial name
- D3L (NCT07847216)
- Testing
- Right Colectomy & D3 Lymphadenectomy
- Volunteers
- 120 people
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears
Remnant Gastric Cancer
The Safety, Feasibility and Oncological Outcomes of Laparoscopic Completion Total Gastrectomy for Remnant Gastric Cancer
This study aims to investigate the safety, feasibility, and long-term oncological outcomes of laparoscopic completion total gastrectomy for remnant gastric cancer.
- Trial name
- NCT02792881
- Testing
- Laparoscopic completion total gastrectomy with D2 lymphadenectomy
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Fujian Medical University
Prostate Cancer
Prospective Asian Multicenter Prostate Cancer Focal Therapy Study (ProAMFocal)
This is a multicenter observational study of patients undergoing focal therapy for prostate cancer in Asia
- Trial name
- ProAMFocal (NCT06491056)
- Testing
- Focal Therapy for Prostate Cancer
- Where
- Singapore
- Volunteers
- 500 people
- Sponsor
- Singapore General Hospital
Prostatic Neoplasms, Hypogonadism
Impact of Peri-operative tEstosterone Levels on oNcological and Functional Outcomes in RadiCal prostatEctomy
Sexual dysfunction is a common side effect of radical prostatectomy (RP) and has a significant negative impact on quality of life.
- Conditions
- Prostatic Neoplasms, Hypogonadism, Testosterone Deficiency
- Trial name
- ENFORCE (NCT04833426)
- Testing
- Testosterone gel
- Where
- 10 sites in Netherlands
- Volunteers
- 140 people
- Sponsor
- Canisius-Wilhelmina Hospital
Neoadjuvant Chemoradiotherapy, Rectal Tumor
Outcomes of Resection at Different Times Between the End of Neoadjuvant Treatment and Surgery
Neoadjuvant radio-chemotherapy (NRCT) represents a milestone in the treatment of selected rectal tumours. Ideal time interval between the end of NRCT and surgery is still debated; a 6-8 weeks time interval is considered optimal…
- Conditions
- Neoadjuvant Chemoradiotherapy, Rectal Tumor, Surgery, Surgery--Complications
- Trial name
- NCT04013347
- Testing
- Rectal Resection
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Campus Bio-Medico University
Breast Neoplasms
OvS Breast: Ovarian Suppression in Breast Cancer Interventions
The goal of this clinical trial is to compare a combined intervention based on physical exercise, nutritional control, and individualized psycho-oncological support can achieve weight control and maintain adequate body…
- Trial name
- ENBI (NCT06727487)
- Testing
- Basic recommendations, Physical exercise, Nutritional advice
- Where
- 2 sites in Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Pontificia Comillas
Malignant Tumor of the Larynx
Stapler Versus Conventional Pharyngeal Repair After Total Larygectomy
This study was done to investigate the efficacy and safety of the linear stapler closure of the pharynx after total laryngectomy.
- Trial name
- NCT06256263
- Testing
- total laryngectomy
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Mansoura University
Supraglottic Squamous Cell Carcinoma, Early Stage (T1-T2, N0-N1,M0)
Treatment of Early Supraglottic Squamous Cell Carcinoma With Advance Technologies
In this project, the investigators will realize an observational, prospective, multicentric and international clinical trial, to objectively compare patients with SSCC according to 3 arms of treatment: Arm 1: Radiotherapy ±…
- Trial name
- SUPRA-QoL (NCT05611515)
- Testing
- TORS
- Where
- Belgium
- Volunteers
- 108 people
- Sponsor
- Centre Hospitalier Universitaire UCLouvain Namur
Colon Cancer, Colon Neoplasm
Long-term Results in Intracorporeal Versus Extracorporeal Anastomosis in Laparoscopic Right Colectomy
Advantages of laparoscopic right colectomy with intracorporeal anastomosis (IA) compared to extracorporeal anastomosis (EA) are widely studied.
- Conditions
- Colon Cancer, Colon Neoplasm, Malignant Neoplasm, Colon Neoplasia
- Trial name
- NCT05446558
- Testing
- Intracorporeal anastomosis, Extracorporeal anastomosis
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Gastric Cancer, Laparoscopic Gastrectomy
Outcomes of Laparoscopic Gastrectomy
A prospective study of the results of laparoscopic approach of gastric carcinoma in western patients is designed. The working hypothesis proposes obtaining similar results to those obtained in the series reported by eastern…
- Trial name
- NCT04652986
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Juan Carlos Martín del Olmo
Colon Cancer
The Effect of Unfavorable Histological Features on the Oncological Outcomes of Colon Cancer
To explore the effect of unfavorable histological features on the clinical outcomes of patients receiving radical resection of colon cancer.
- Trial name
- NCT03794193
- Testing
- Radical resection of colon cancer
- Volunteers
- 1,367 people
- Sponsor
- Peking Union Medical College Hospital
Renal Cell Carcinoma
Oncological and Functional Outcomes of Laparoscopic Partial Nephrectomy in Renal Cell Carcinoma Stages T1 Versus T2a: Prospective Comparative Study.
RCC represents around 3% of all cancers, with the highest incidence occurring in Western countries . Within the several RCC risk factors identified, smoking, obesity, and hypertension are most strongly associated with RCC .
- Trial name
- NCT05486871
- Testing
- laparoscopic partial nephrectomy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Kidney Neoplasms
Assessment of Oncological and Functional Outcomes After Robot Assisted Partial Nephrectomy Versus Laparoscopic Partial Nephrectomy
Currently, partial nephrectomy (PN) is considered as the gold standard treatment modality for small renal masses. In this setting, robot-assisted and conventional laparoscopic approaches are gaining more consensus every day.
- Trial name
- NCT02924922
- Testing
- Laparoscopic partial nephrectomy, Robot assisted partial nephrectomy, Conventional laparoscopic instruments
- Where
- Switzerland
- Volunteers
- 85 people
- Sponsor
- Luzerner Kantonsspital