Clinical trials: Oncological Patients
Thoracic Neoplasm, Pulmonary Nodules
Study of Collection and Analysis of Clinical, Anamnestic, Functional, Biological Data Through the Support of Artificial Intelligence to Evaluate the Possibility of Defining a Digital Twin of the Lung (LUCE)
This research study aims to retrospectively and prospectively analyze the clinical, anamnestic, functional, biological data of patients who have performed or will perform non-contrast chest photon count CT.
- Conditions
- Thoracic Neoplasm, Pulmonary Nodules, Non-oncological Pulmonary Pathologies
- Trial name
- NCT07517393
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- Casa di Cura Dott. Pederzoli
Heredo Familial Tumors, Psycho Oncological Support
Patient Experiences After Risk-Reducing Mastectomy Among Women Carrying BRCA1/2 Pathogenic Variants Without a Diagnosis of Breast Cancer
This is a descriptive, exploratory cross-sectional, single-center national study. The study asks a sample of women carrying pathogenic variants associated with hereditary breast and ovarian cancer who have undergone risk-reducing…
- Trial name
- NCT07821593
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
ERAS, Gynecologic Surgery
Enhanced Recovery After Surgery (ERAS) in Patients Undergoing Gynecologic Surgery
Enhanced Recovery After Surgery (ERAS) is a multidisciplinary perioperative care program designed to reduce surgical stress, accelerate postoperative recovery, and improve clinical outcomes.
- Conditions
- ERAS, Gynecologic Surgery, Gynecologic Oncological Pelvic/Abdominal Surgery
- Trial name
- NCT07764276
- Testing
- Enhanced Recovery After Surgery (ERAS), Conventional Perioperative Care
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Sperm Preservation in Oncological Patients, Fertility
Presence of SARS-CoV-2 (COVID-19) in Semen: Impact on Fertility Preservation in Male Oncological Patients ?
During the COVID-19 pandemic, the French Agency of Biomedicine has recommended maintaining fertility preservation for patients requiring immediate oncological treatments exhibiting gonadotoxic effects.
- Conditions
- Sperm Preservation in Oncological Patients, Fertility, Cryopreservation
- Trial name
- FERTICOVID (NCT04487639)
- Testing
- SARS-CoV-2 research in nasopharyngeal swab, sperm and serologics
- Where
- 16 sites in France
- Volunteers
- 129 people
- Sponsor
- University Hospital, Clermont-Ferrand
Oncological Patients, Tyrosine Kinase Inhibitor
The TASTY-training Study
A multicentre non-blinded randomised intervention trial with a parallel cluster design. The multicentre study will be performed at 12 hospitals in the Netherlands.
- Trial name
- TASTY-training (NCT07258589)
- Testing
- Taste and smell training
- Where
- 11 sites in Netherlands
- Volunteers
- 90 people
- Sponsor
- University Medical Center Groningen
Sarcopenia in Elderly, Frailty/Sarcopenia
Frailty in the Elderly Oncological and Oncohematological Patient.
The Italian population is progressively aging, and cancer incidence increases with age. Older patients are at higher risk of frailty, a condition associated with adverse outcomes such as disability, falls, hospitalization, and…
- Conditions
- Sarcopenia in Elderly, Frailty/Sarcopenia, Oncological Patients, Hematologic Disease
- Trial name
- SALICE (NCT07624370)
- Testing
- Frailty evaluation
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- Azienda Socio Sanitaria Territoriale Ovest Milanese, Ospedale di Legnano
Oncological Patients, Major Surgery
Prehabilitation in Oncological Patients Undergoing Major Gastrointestinal Surgery (PROGRESS)
The importance of postoperative rehabilitation on physical performance and recovery is well-recognized. However, the preoperative period constitutes a unique opportunity to address comorbidities and modifiable risk factors…
- Trial name
- PROGRESS (NCT06404489)
- Testing
- Multimodal prehabilitation Program
- Where
- 2 sites in Italy
- Volunteers
- 400 people
- Sponsor
- Università Vita-Salute San Raffaele
Oncological Disease, Fertility Preservation
Ovarian Tissue Cryopreservation Combined With Oocyte Cryopreservation Versus Oocyte Cryopreservation Alone
Fertility preservation is a crucial aspect of care for oncological patients undergoing gonadotoxic treatments such as chemotherapy, radiotherapy, or surgery, which can significantly reduce ovarian reserve and cause infertility or…
- Trial name
- NCT07546123
- Where
- Italy
- Volunteers
- 127 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Oncological Disease, Fertility Preservation
Ovulation Induction With GnRH Analogue or Dual Trigger?
Most medically assisted procreation (ART) techniques, including oocyte cryopreservation for fertility preservation, involve controlled ovarian stimulation.
- Trial name
- NCT07546136
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Patients in Situation of Last Days of Their Life, Oncological and no Onoclogical Disease
Evaluation of CUDECA Cui-DAR Plan in People With Oncological and Non-oncological Diseases in the Last Days of Their Lives (CUIDARCUDECA)
Cudeca, an independent non-profit organization located in Malaga (Spain), treats patients with advanced and terminal disease. It has developed Cui-DAR Cudeca plan, a care plan for the care of patients in situations of last days…
- Trial name
- CUIDARCUDECA (NCT07446673)
- Testing
- Care Plan Cui-dar CUdeca
- Where
- 3 sites in Spain
- Volunteers
- 348 people
- Sponsor
- Cudeca Hospice Foundation
Immuno-modulation, Immuno-suppression
Analysis of the Specificity and Persistence of Nasal Immune Responses to Respiratory Viral Antigens in Immunocompromised and Healthy Cohorts
The goal of this observational study is to characterize nasal mucosal immunity to respiratory viruses, such as SARS-CoV-2, in immunocompromised individuals and healthy volunteers.
- Conditions
- Immuno-modulation, Immuno-suppression, Immunocompromised Patients, Healthy Subjects
- Trial name
- NCT07295535
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Liver Transplantation, HCC
HOPE Against Cancer Recurrence in HCC
Liver transplantation is often performed to treat liver cancer, or hepatocellular carcinoma (HCC), in patients with impaired liver function due to cirrhosis. A shortcoming, however, is tumor recurrence after transplantation.
- Conditions
- Liver Transplantation, HCC, Oncological Outcomes
- Trial name
- HOPE4Cancer (NCT06717919)
- Testing
- Hypothermic oxygenated perfusion, Conventional cold storage
- Where
- 37 sites in United States, Austria and 15 more
- Volunteers
- 220 people
- Sponsor
- Philipp Dutkowski
Malnutrition in Elderly, Oncological Patients
Impact of Specific Oligomeric Supplementation in Oncologic Patients Undergoing Radiotherapy With Malnutrition or at Risk.
An observational, prospective, multicenter study to be conducted in 5 hospitals in Spain. Patients with cancer undergoing radiotherapy are malnourished or at risk of malnutrition.
- Conditions
- Malnutrition in Elderly, Oncological Patients, Digestive Disorders
- Trial name
- NORMA (NCT07035132)
- Testing
- Oral supplementation with nutritional oligomeric formula
- Where
- 4 sites in Spain
- Volunteers
- 132 people
- Sponsor
- Outcomes'10
Oncological Comorbidities (e. g. Hypertension, Diabetes, Malnutrition)
AI-Assisted Comprehensive Management for Cancer Patients With Comorbidities (GCOG-CG001)
Combined with the digital whole process management data pool, a multi-modal data fusion framework is developed, and an AI model is established to realize risk stratification and personalized treatment Recommendation and dynamic…
- Trial name
- GCOG-CG001 (NCT07136727)
- Testing
- AI-assisted comprehensive management system
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- The First Affiliated Hospital of Xinxiang Medical College
Stem Cell Transplant, Stem Cell Transplantation
Fertility Protection for Children, Adolescents and Young Adults
This study focuses on improving fertility preservation and long-term care for children, adolescents, and young adults (CAYA) undergoing cancer treatments or stem cell transplantation.
- Conditions
- Stem Cell Transplant, Stem Cell Transplantation, Oncological Outcomes, Oncological Patients
- Trial name
- FeProCAYA (NCT06692868)
- Where
- Germany
- Volunteers
- 2,000 people
- Sponsor
- University of Ulm
Database, Prostate Cancer
National Robotics-Assisted Radical Prostatectomy Database
In Australia, nearly 70 men are diagnosed with Prostate cancer every day. Prostate removal (Radical Prostatectomy) is the proven treatment option to control cancer spread.
- Conditions
- Database, Prostate Cancer, Robotic-assisted Radical Prostatectomy, Surgical Outcomes
- Trial name
- RASOR (NCT06279260)
- Where
- 8 sites in Australia
- Volunteers
- 10,000 people
- Sponsor
- Melbourne Health
Perioperative Outcomes, Oncological Outcomes
Robotic Versus Laparoscopic Right Hemicolectomy With Complete Mesocolic Excision
the investigators performed a retrospective multicenter propensity score matching study. From July 2016 to July 2021, 382 consecutive patients from different Chinese surgical departments were available for inclusion out of an…
- Trial name
- NCT05457426
- Testing
- robotic right hemicolectomy with CME
- Where
- 3 sites in China
- Volunteers
- 382 people
- Sponsor
- Third Military Medical University
Patients With Suspected Ovarian Carcinoma, Non Oncological Patients or With Endometriosis
Artificial inTelligence in eNdometriosis-related ovArian Cancer and Precision Surgery in eNdometriosis-related ovArian Cancer
Endometriosis (EMS) is a chronic, invaliding, inflammatory gynaecological condition affecting 10-15% of women in reproductive age.
- Trial name
- ATENA (NCT05161949)
- Where
- Italy
- Volunteers
- 240 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Patient Reported Outcome, Oncological Safety
Patient Report Outcome and Oncological Safety -Oncoplastic and Conventional BCS Cohort
Breast-conserving surgery (BCS) is the traditional surgical treatment for early-stage breast cancer patients. There are evidences indicating that oncoplastic BCS could improve cosmetic outcomes and/or quality of life, and has…
- Conditions
- Patient Reported Outcome, Oncological Safety, Breast-conserving Surgery, Breast Cancer Female
- Trial name
- NCT05054777
- Testing
- oncoplastic breast-conserving surgery, conventional breast-conserving surgery
- Volunteers
- 5,000 people
- Sponsor
- Shandong Cancer Hospital and Institute
Oncological Patients, Virtual Reality
Look of Life 2.0. Virtual Reality for Cancer Patients in Home Palliative Care
Oncological disease, in addition to undermining the physical health and autonomy of the patient, is often accompanied by significant anxious and depressive symptoms that can compromise the quality of life of both patient and…
- Trial name
- LOL2020_ANT (NCT04966468)
- Testing
- Virtual Reality, Control
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Fondazione ANT Franco Pannuti ETS