Clinical trials: One-Lung Ventilation
Video-assisted Thoracoscopic Surgery, One-Lung Ventilation
Compared Unidirectional Valve Apparatus and Occluding the Non-ventilated Endobronchial Lumen for Lung Collapse.
With the rapid advancement of thoracoscopic surgery in recent years, surgeons have set higher standards for the quality of non-ventilated lung collapse.
- Trial name
- NCT06210256
- Testing
- unidirectional valve apparatus, occluding the non-ventilated endobronchial lumen
- Where
- China
- Volunteers
- 192 people
- Sponsor
- Sichuan University
One Lung Ventilation
Evaluation Of One Lung Ventilation With Ultrasound in Thorax Surgery Operations
BACKGROUND: The aim of this study is to evaluate the confirmation of double lumen tube placement with thoracic Ultrasound (USG) in thorax surgery operations with one lung ventilation.
- Trial name
- NCT06064773
- Testing
- thoracic USG
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Dokuz Eylul University
One Lung Ventilation OLV, Esophageal Atresia
The Effect of Dexmedetomidine on Oxygen During One Lung Ventilation in Pediatric Surgery.
The children who will undergo OLV (one lung ventilation) through general anesthesia will be divided into two groups: The first will be intravenous infusion of dexmedetomidine at 0.4 mcg / kg / hour, and the second will be…
- Conditions
- One Lung Ventilation OLV, Esophageal Atresia, Hydrocystoma, Pneumonectomy
- Trial name
- RCT (NCT04932746)
- Testing
- Dexmedetomidine
- Where
- Syria
- Volunteers
- 110 people
- Sponsor
- Damascus University
Thoracic Surgery, One-lung Ventilation
Individualized PEEP in Thoracic Surgery
Intraoperative protective ventilation with low tidal volumes (TV), positive end-expiratory pressure (PEEP) and possibly lung recruitment maneuvers (RMs) reduces postoperative pulmonary complications.
- Conditions
- Thoracic Surgery, One-lung Ventilation, Respiratory Mechanics, Artificial Respiration
- Trial name
- NCT04740151
- Testing
- Best PEEP, Standard PEEP
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Trieste
Ventilator-Induced Lung Injury, Lung Ventilator
Respiratory Mechanics During One-lung Ventilation
Intraoperative lung protective ventilatory strategy has been widely recognized to reduce postoperative pulmonary complications in laparotomy and laparoscopic surgeries.
- Conditions
- Ventilator-Induced Lung Injury, Lung Ventilator, One-lung Ventilation
- Trial name
- NCT04519606
- Testing
- Optimal lung compliance during OLV
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- E-DA Hospital
One-Lung Ventilation, Hypoxemia During Surgery
Oxygen Reserve Index in One-Lung Ventilation During Elective Thoracic Operations
The investigators' goal is to perform an observational cohort study investigating the use of oxygen reserve index (ORi) in patients undergoing elective thoracic surgery and one-lung ventilation (OLV).
- Conditions
- One-Lung Ventilation, Hypoxemia During Surgery, Oxygen Reserve Index, Perfusion Index
- Trial name
- NCT05050552
- Testing
- Masimo Radical-7 Pulse CO-Oximeter
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Trakya University
Thoracic Surgery, One-lung Ventilation
Intraoperative Neuromuscular Blockade and Postoperative Atelectasis
During one-lung ventilation in thoracic surgery, the intensity of neuromuscular blockade may change the compliance and resistance of ventilated lung, thereby affecting postoperative atelectasis.
- Trial name
- NCT03503565
- Testing
- intraoperative neuromuscular blockade
- Where
- South Korea
- Volunteers
- 118 people
- Sponsor
- Kyung Hee University Hospital at Gangdong
One-Lung Ventilation, Postoperative Complications
Driving Pressure and Postoperative Pulmonary Complications in Thoracic Surgery
Pulmonary complications are the most common complication in thoracic surgery and the leading cause of mortality.Therefore, lung protection is utmost important, and protective ventilation is strongly recommended in thoracic…
- Conditions
- One-Lung Ventilation, Postoperative Complications, Driving Pressure, Postoperative Pulmonary Complication
- Trial name
- NCT04260451
- Testing
- ventilation
- Where
- South Korea
- Volunteers
- 1,300 people
- Sponsor
- Samsung Medical Center
One-Lung Ventilation, Obesity
Individualized vs Low PEEP in One Lung Ventilation
The aim of the prospective crossover study is to investigate the effect of individualized positive end-expiratory pressure (PEEP) on measures of tissue oxygenation, compared with low PEEP.
- Conditions
- One-Lung Ventilation, Obesity, Lung Diseases
- Trial name
- NCT03569774
- Testing
- One-lung ventilation with individualized PEEP, One-lung ventilation with low PEEP
- Where
- United States
- Sponsor
- Dionne Peacher
Methylprednisolone;Dihydroxypropyltheophylline;One Lung Ventilation;Respiratory Dynamics
Clinical Study of the Effect of Methylprednisolone Combined
Through the design of RCT study, the preoperative use of drugs (methylprednisolone + dihydroxypropyltheophylline) as intervention measures, the patients undergoing thoracoscopic lobectomy as the main research object, through the…
- Trial name
- NCT04810819
- Testing
- Methylprednisolone 40 MG Injection;Dihydroxypropyltheophylline;
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Qianfoshan Hospital
One-Lung Ventilation, Thoracic Surgery
The Effect of Anesthesia on Cerebral Oxygenation
One-lung ventilation (OLV) may cause negative changes in the oxygenation of cerebral tissue which results in postoperative cognitive dysfunction.
- Conditions
- One-Lung Ventilation, Thoracic Surgery, Postoperative Cognitive Complications
- Trial name
- NCT04760262
- Testing
- Sevoflurane, Propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
One Lung Ventilation
Effectiveness of Lung Sono in One-lung Ventilation
To observe the effectiveness of ultrasound-guided alveolar recruitment in thoracic surgery with one-lung ventilation(OLV).
- Trial name
- NCT03770793
- Testing
- Lung-sono guided
- Where
- South Korea
- Volunteers
- 166 people
- Sponsor
- Seoul National University Hospital
Lung Collapse, One-Lung Ventilation
Physiology of Lung Collapse Under One-Lung Ventilation: Underlying Mechanisms
Lung isolation technique and one-lung ventilation (OLV) are the mainstays of thoracic anesthesia. Two principal lung isolation techniques are mainly use by clinicians, the double lumen tubes (DLT) and the bronchial blockers (BB).
- Conditions
- Lung Collapse, One-Lung Ventilation, Thoracic Surgery, Video-Assisted
- Trial name
- PLC-OLV (NCT02919267)
- Testing
- Double lumen tube, Bronchial blocker
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Laval University
One-lung Ventilation
Clamping the Double Lumen Tube
Nowadays, lung isolation techniques are an essential part of thoracic anesthesia. The two principal devices used in order to achieve one-lung ventilation (OLV) are the double lumen tube (DLT) and the bronchial blocker (BB).
- Trial name
- C-TDL (NCT03508050)
- Testing
- Clamping the Double Lumen Tube
- Where
- Canada
- Volunteers
- 37 people
- Sponsor
- Jean Bussières
Thoracic Surgery, One Lung Ventilation
Insertion Depth of Left-sided Double-lumen Tube: a New Predictive Formula
The authors developed a formula for predicting the accurate depth of DLT insertion into the appropriate bronchus based on height as follows [The predicted insertion depth of left DLT (cm) equals 0.249 × (BH)0.916] [R].
- Conditions
- Thoracic Surgery, One Lung Ventilation, Left-sided Double Lumen Tube
- Trial name
- NCT04329416
- Testing
- Predicted depth of insertion, Optimized depth of insertion, Adjustment of depth of insertion
- Where
- Saudi Arabia
- Volunteers
- 65 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Lung Diseases, Ultrasonography
Lung Ultrasonography vs Fiberoptic Bronchoscopy for Aiding Lung Collapse in Patient Using Double Lumen Tube
The study contains the result from a comparison of diagnostic outcomes about lung collapse by using lung ultrasonography as a new diagnostic test compares to fiberoptic bronchoscopy as the standard test.
- Conditions
- Lung Diseases, Ultrasonography, Fiberoptic Bronchoscopy, One Lung Ventilation
- Trial name
- NCT03314519
- Testing
- Lung ultrasonography by experienced anaesthesiologist, Fiberoptic bronchoscopy for double lumen tube's position
- Where
- Thailand
- Volunteers
- 200 people
- Sponsor
- Mahidol University
Oxygenation During One Lung Ventilation
Nebulized Epoprostenol (FLOLAN) and Phenylephrine on One Lung Ventilation (OLV)
This is a pilot study of a new use of Epoprostenol via inhalation (Epoprostenol is approved for intravenous use). The purpose of this study is to administered inhaled Epoprostenol and intravenous Phenylephrine to improve arterial…
- Trial name
- FLOLAN (NCT02748265)
- Testing
- Inhaled Epoprostenol and phenylephrine, Sevoflurane, Propofol
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- University Health Network, Toronto
Thoracic Anesthesia, Lung Ultrasound
Auscultation, Lus, Fob In Olv (ALFIO)
The study will be to demonstrate that, in patients undergoing elective thoracic surgery, lung ultrasound (LUS) in OR is more sensitive, specific and accurate method than thoracic auscultation, for the evaluation of OLV.
- Conditions
- Thoracic Anesthesia, Lung Ultrasound, Left Double-lumen Tube, Selective Bronchial Intubation
- Trial name
- ALFIO (NCT03912311)
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- University of Parma
Obese Patients, One Lung Ventilation
Effects of 1:1 Inspiratory to Expiratory Ratios on Oxygenation and Intrapulmonary Shunt Fraction During One Lung Ventilation in the Obese Patients
One-lung ventilation, even in patients with healthy weight, causes an impairment in gas-exchange and respiratory mechanics. We hypothesized that oxygenation during the one-lung ventilation in obese patients would be improved by…
- Trial name
- NCT02185378
- Testing
- I:E ratio 1:2, I:E ratio 1:1
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Yonsei University
One-Lung Ventilation, Thoracic Surgery, Video-Assisted
Comparison Between CPAP and HFJV During One-lung Ventilation in VATS
This study compares two ventilatory techniques (continuous positive airway pressure vs high frequency jet ventilation) during one-lung ventilation (OLV) in video-assisted thoracic surgery (VATS).
- Trial name
- NCT03296449
- Testing
- CPAP, HFJV
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Hospital General Universitario de Alicante