Clinical trials: One-Lung Ventilation
Postoperative Pain
Comparison of Paravertebral Versus Epidural Block for Post-thoracotomy Pain Control
This is a randomized, assessor-blinded, non-inferiority clinical trial comparing continuous thoracic paravertebral block (BPV) versus continuous thoracic epidural block (BPD) for postoperative pain control in adult patients…
- Trial name
- NCT07763249
- Testing
- Continuous Thoracic Paravertebral Block, Continuous Thoracic Epidural Block
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
One Lung Ventilation, Endobronchial Blocker
A Blind Maneuver to Position an Endobronchial Blocker
One-lung ventilation can be provided by an endobronchial blocker. The Uniblocker® (Fuji Systems Corporation, Tokyo, Japan) was relatively recently introduced into clinical practice.
- Conditions
- One Lung Ventilation, Endobronchial Blocker, Thoracic Surgery, Fiberoptic Bronchoscopy
- Trial name
- NCT01364142
- Testing
- endobronchial blocker
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Seoul National University Hospital
Lung Diseases
Impact of Patient Position on the Success in Placing Triple-cuffed Double Lumen Endotracheal Tube
Triple-cuffed double lumen endotracheal tube (TC-DLT, ANKOR tube. Insung corp., Korea) which was developed to isolate lung without endotracheal bronchoscope guidance has additional carinal cuff placed between bronchial tube cuff…
- Trial name
- NCT05462275
- Testing
- Intubation using 3-cuffed double lumen endotracheal tube
- Where
- South Korea
- Volunteers
- 167 people
- Sponsor
- Hansu Bae
Pneumonia, Postoperative, Anesthesia
Reducing Pneumonia with LMA in Lung Wedge Resection
This retrospective cohort study aims to evaluate whether spontaneous breathing laryngeal mask anesthesia (LMA-SBA) reduces the incidence of postoperative pneumonia compared to single-lung isolation mechanical ventilation in…
- Conditions
- Pneumonia, Postoperative, Anesthesia, Thoracic Surgery, Thoracoscopic Wedge Resection
- Trial name
- NCT06873958
- Where
- China
- Volunteers
- 700 people
- Sponsor
- Hai Feng
Delirium, Thoracic Surgery
Cerebral Oxygen Desaturation and Post-Operative Delirium in Thoracic Surgical Patients
This study will assess the incidence and risk factors for post-operative delirium in patients undergoing thoracotomy. Specifically, the study will assess if there is any relationship between an intra-operative decrease in brain…
- Trial name
- NCT03165539
- Testing
- Cerebral oxygen saturation monitoring
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University of Manitoba
Surgery, One-lung Ventilation
Esophageal Pressure Measurements During One-lung Ventilation
The investigators will assess the feasibility and validity of esophageal pressure measurements during one-lung ventilation in the lateral position for surgery by comparing to lung collapse estimated from electrical impedance…
- Trial name
- NCT04725318
- Testing
- One-lung ventilation
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Beth Israel Deaconess Medical Center
Mask Ventilation, Obese Patients (BMI ≥ 30 kg/m²)
Comparison of Mask Ventilation in Obese Patients by Differents One Hand Techniques
The goal of this controled clinical trial study to know if hook tecnique method is better than other traditional one hand ventilation methods in acheiving effective ventilation in obese patients .
- Conditions
- Mask Ventilation, Obese Patients (BMI ≥ 30 kg/m²), Obesity & Overweight, Bag-mask Ventilation
- Trial name
- E&c / T&E (NCT06817083)
- Testing
- E-C Clamp Technique, T-E Technique, The Hook Technique
- Where
- Egypt
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Aswan University
One Lung Ventilation, Intubation Complication
Videolaryngoscopy vs Direct Laryngoscopy for Double Lumen Tube Lumen Tube Placement - A Multicentre Randomized-controlled Trial (VOLCANO Study)
The general aim of the study is to observe whether the use of the Mc Grath™ videolaryngoscope instead of direct laryngoscopy can represent, as in the case of the single-lumen tube, an added value in the placement of the…
- Trial name
- VOLCANO (NCT06466759)
- Testing
- Mc Grath Videolaryngoscope
- Volunteers
- 750 people
- Sponsor
- Luca Brazzi
Endotracheal Tube Wrongly Placed During Anesthetic Procedure, Surgical Procedure, Unspecified
Displacement Between PVC and Silicon DLT
The purpose of this study is to compare difference of displacement between Polyvinyl Chloride(PVC) and Silicon double-lumen endobronchial tubes(DLTs) during changing position from supine to lateral in thoracic surgery.
- Trial name
- NCT02691468
- Testing
- PVC DLT, silicon DLT
- Where
- South Korea
- Volunteers
- 108 people
- Sponsor
- Yeungnam University College of Medicine
Chronic Obstructive Pulmonary Disease (COPD)
Study Comparing Dual Combination of Product (Budesonide and Formoterol) Given Via Two Different Inhalers. To See Which One Results in the Best Effect on Breathing.
Study comparing the same drugs as a dual combination product (budesonide and formoterol) given via two different inhalers. To see which one results in the best effect on breathing.
- Trial name
- NCT04078126
- Testing
- BFF, Symbicort Turbuhaler
- Where
- 4 sites in Germany
- Volunteers
- 35 people
- Sponsor
- AstraZeneca
Lung Diseases
Comparison of Two Strategies of One-lung Ventilation in Patients Undergoing Carcinological Lung Resection Surgery.
During thoracic surgery, one-lung ventilation (OLV) is associated with hypoxemia, lung injury, and perioperative respiratory complications.
- Trial name
- I-PEEP-THO (NCT05525312)
- Testing
- "Open-lung" protective ventilation strategy, "Standard" protective ventilation strategy
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Montpellier
One-lung Ventilation
Two-staged Approach in Positioning Endobronchial Blockers Without Fiberoptic Guidance
The purpose of this study is to find a novel method for placing endobronchial blockers without fiberoptic guidance to provide one-lung isolation during anesthesia for thoracic surgery.
- Trial name
- NCT02981537
- Testing
- two-staged endobronchial blocker insertion, single-staged endobronchial blocker insertion
- Where
- South Korea
- Volunteers
- 94 people
- Sponsor
- Seoul National University Hospital
Thoracic Surgery, Cognitive Dysfunction
Cerebral Desaturation and Postoperative Dysfunction After Thoracic Surgery
The purpose of this study prospective observational study is to determine cognitive dysfunction incidence after thoracic surgery.
- Trial name
- NCT03805880
- Testing
- cerebral desaturation monitoring and cognitive examination
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Roma La Sapienza
One-lung Ventilation
Clamping the Double Lumen Tube
Nowadays, lung isolation techniques are an essential part of thoracic anesthesia. The two principal devices used in order to achieve one-lung ventilation (OLV) are the double lumen tube (DLT) and the bronchial blocker (BB).
- Trial name
- C-TDL (NCT03508050)
- Testing
- Clamping the Double Lumen Tube
- Where
- Canada
- Volunteers
- 37 people
- Sponsor
- Jean Bussières
Lung Cancer (Diagnosis)
Effect of Apneic Oxygenation of the Non-ventilated Lung During Lung Cancer Surgery.
This study investigates the effect of apneic oxygenation of the non-ventilated lung on local and systemic inflammatory response during lung cancer surgery.
- Trial name
- NCT07393490
- Testing
- Apnoeic Oxygenation, Standard Ventilation
- Where
- Croatia
- Volunteers
- 56 people
- Sponsor
- Osijek University Hospital
Any Healthcare Professional, Agreement to Participate
Impact of Stress on Management of BAVU Ventilation (Self-filling Bag With One-way Valve) by Healthcare Professionals.
The goal of this observational study is to learn about the impact of stress on the manual ventilation through Self-filling Bag With One-way Valve.
- Conditions
- Any Healthcare Professional, Agreement to Participate, Who May be Required to Perform Manual Ventilation
- Trial name
- SIMBAVU 2 (NCT06481618)
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Double Lumen Tube
One Lung Ventilation: Double Lumen Tube
One lung ventilation (OLV) has become a standard procedure for the vast majority of interventions in pulmonary surgery. It is used in both techniques: thoracotomy and videothoracoscopy (VATS).
- Trial name
- NCT02857504
- Testing
- double lumen tube with a hook, double lumen tube without a hook
- Where
- Slovenia
- Volunteers
- 30 people
- Sponsor
- University Medical Centre Ljubljana
Thoracic Diseases
Mechanical Insufflator-exsufflator in Patients After Video-assisted Thoracoscopic Operations With One-lung Ventilation
Postoperative pulmonary complications (PPC) are a common problem in patients undergoing surgery using one-lung invasive ventilation.
- Trial name
- NCT06180148
- Testing
- Mechanical insufflator-exsufflator
- Where
- Russia
- Volunteers
- 31 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Thoracic Anesthesia, One Lung Ventillation (OLV)
Association Between One Lung Ventilation and Myocardial Injury Markers (Troponin T and I) in Thoracic Surgical Procedures (OLVTIS)
This prospective single-group cohort study aims to investigate the association between the One-Lung Ventilation (OLV) technique and myocardial injury, as measured by postoperative Troponin T and Troponin I levels, in patients…
- Trial name
- OLVTIS (NCT07302243)
- Where
- Indonesia
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Universitas Jenderal Soedirman
Pulmonary Disease, Chronic Obstructive, Hyperoxia
Effective High Aerobic Intensity Endurance Training Regimes in Chronic Obstructive Pulmonary Disease (COPD) Patients
4 times 4 minutes interval training with and without hyperoxia is more effective than low intensity endurance training.
- Trial name
- NCT00658853
- Testing
- 4 times 4 minutes high aerobic intensity one leg cycling
- Where
- Norway
- Volunteers
- 26 people
- Sponsor
- Norwegian University of Science and Technology