Clinical trials: Ongoing Pregnancy Rate
Infertility
A Comparison of Ongoing Pregnancy Rate Between Cleavage Stage and Early Compacting Embryo Transfer at 66±2 Hours After ICSI Using Single Step Culture Medium
A comparison of ongoing pregnancy rate between cleavage stage and early compacting embryo transfer at 66±2 hours after ICSI using single step culture medium
- Trial name
- NCT02987075
- Testing
- Compacting embryo transferring, Non- compacting embryo transferring
- Where
- Vietnam
- Volunteers
- 430 people
- Sponsor
- Vietnam National University
Serum Progesterone Levels, Progesterone Supplementation
Effect of Intramuscular Progesterone Supplementation on Clinical and Ongoing Pregnancy Rates in Patients With Low Serum Progesterone Levels on the Day of Embryo Transfer in Artificial Frozen Cycles
The aim of this study is to investigate whether intramuscular progesterone supplementation will improve clinical pregnancy rates and ongoing pregnancy rates in patients with decreased serum progesterone levels on the day of…
- Conditions
- Serum Progesterone Levels, Progesterone Supplementation, Frozen Embryo Transfer, Clinical Pregnancy Rates
- Trial name
- NCT04837768
- Testing
- Twice-daily transvaginal progesterone supplementation, Twice-weekly intramuscular + Twice-daily transvaginal progesterone supplementation
- Where
- 2 sites in Egypt
- Volunteers
- 354 people
- Sponsor
- Cairo University
Improvement of Embryo Transfer Technique, Improvement of Implantation
Comparative Study of Three Different Embryo Transfer Media in ICSI Cycles
The study design is a prospective randomized uncontrolled clinical trial. It will include 150 cases. The aim of this study is to compare the efficacy of three different media used for embryo transfer regarding "chemical and…
- Trial name
- NCT02792673
- Testing
- embryos will be transferred using a medium of 0.5 mg/mL of Hyaluronan-enriched medium (EmbryoGlue®, Vitrolife, Sweden), embryos will be transferred using a medium of 30% Protein-supplemented Culture Medium (Global total®, Life Global group, Canada), a novel technique in which embryos will be transferred using a medium of autologous Follicular Fluid
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- South Valley University
Pregnancy Related, Glucose, Low Blood
Interval Versus Continuous Exercise During Pregnancy
The objective of this randomized cross-over design was to investigate the fetal well-being and maternal glycemic response to an acute bout of aerobic high-intensity interval training (HIIT) and moderate-intensity continuous…
- Conditions
- Pregnancy Related, Glucose, Low Blood, Fetal Heart Rate or Rhythm Abnormality Affecting Fetus, Fetal Blood Flow
- Trial name
- NCT05369247
- Testing
- High intensity Interval Training, Moderate Intensity Continuous Training
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Infertility, Female, Infertility
Phase II Clinical Trial to Evaluate the Ongoing Pregnancy Rate With OXO-001 in IVF/ICSI With Donor Oocytes.
The main objective of this clinical research trial is to test the efficacy of OXO-001 in a daily oral administration increasing the pregnancy rate in IVF/ICSI by preparing the uterus to receive the embryo.
- Trial name
- OXOART2 (NCT05076032)
- Testing
- OXO-001
- Where
- 28 sites in Czechia, Poland and 1 more
- Volunteers
- 408 people
- Sponsor
- OXOLIFE
Ongoing Pregnancy Rate, Vitamin D
The Effect of Vitamin D on in Vitro Fertilization Outcome
To date, several studies have been done to explore the relationship between Vitamin D level and IVF outcome; however, the results are controversial. Sample sizes in these studies mentioned above were relatively small.
- Conditions
- Ongoing Pregnancy Rate, Vitamin D, in Vitro Fertilization
- Trial name
- NCT02361827
- Testing
- Embryo transfer
- Where
- China
- Volunteers
- 688 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Pregnancy - Labor Monitoring, Labor and Childbirth
Wearable Ultrasound Patch in Parturients
This study will assess an investigational ultrasound patch placed on the maternal abdomen to noninvasively monitor uterine activity, obtain fetal images and physiologic measurements in labor.
- Conditions
- Pregnancy - Labor Monitoring, Labor and Childbirth, Fetal Heart Rate Tracing
- Trial name
- NCT07871903
- Testing
- wearable ultrasound patch
- Volunteers
- 40 people
- Sponsor
- Stanford University
Infertility, Implantation Failure
ISM1 Versus EmbrioGen Media for Embryo Culture With Previous Failure Implantation in ART Treatments
Recently, it has been suggested that culture of embryos in EmbryoGen medium can increase the live birth rate in IVF patients with a previous history of pregnancy loss.
- Trial name
- NCT01689454
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Biogenesi
Infertility
Efficacy and Safety of Crinone Versus Combination Medication (ACCESS)
The study to compare to the efficacy and safety of Crinone versus combination medication in infertile women receive frozen-thawed embryo transfer (FET) in artificial cycles (AC).
- Trial name
- NCT03858049
- Testing
- Crinone, Duphaston
- Where
- China
- Volunteers
- 172 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Infertility
Follicular Flushing in Patients With Suboptimal Responses
The aim of the present study is to determine the effect of follicular flushing on the ongoing pregnancy rate in patients who developed four or fewer follicles of 14mm following standard ovarian stimulation for IVF.
- Trial name
- NCT02277210
- Testing
- Flushing
- Where
- China
- Volunteers
- 4 people
- Sponsor
- The University of Hong Kong
Acute Kidney Injury
Effect of Filter Lifespan in CRRT on New Infections in Critically Ill Patients With AKI
This observational study aims to explore the factors that influence the risk of new infections in critically ill patients with acute kidney injury (AKI) requiring continuous renal replacement therapy (CRRT) in the UK.
- Trial name
- CRRTinfUK (NCT07903519)
- Where
- United Kingdom
- Volunteers
- 630 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Type 1 Diabetes Mellitus
Effect of CSII and CGM on Progression of Late Diabetic Complications
The purpose of the study is to investigate whether the combination of insulin pump therapy and continued glucose monitoring (CGM) is superior to multiple daily insulin injections to prevent progression of albuminuria in patients…
- Trial name
- NCT01454700
- Testing
- Insulin pump therapy (CSII) plus continuous glucose monitoring (CGM), Multiple daily insulin injections (MDI)
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Steen Andersen
Infertility, Female
Efficacy and Safety of Gushen Antai Pill on Ongoing Pregnancy Rate in Women With Normal Ovarian Reserve Undergoing IVF-ET
The purpose of this study is to investigate whether oral Gushen Antai pills supplementation for luteal phase support will improve ongoing pregnancy rate in women with normal ovarian reserve in fresh embryo transfer cycles.
- Trial name
- GSATP-FreET (NCT04872660)
- Testing
- Gushen Antai Pill
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Shandong University of Traditional Chinese Medicine
Infertility
International Pilot Study for Dual Non-invasive Assesment of Embryo Development
Choosing the best embryo is one of the major challenges for achieving success in in vitro fertilization (IVF). Traditionally, embryo evaluation has been based on morphological quality (how the embryo looks like) and chromosomal…
- Trial name
- PANDORA (NCT06524648)
- Testing
- niPGT-A
- Where
- 8 sites in Austria, Spain and 1 more
- Volunteers
- 200 people
- Sponsor
- Igenomix
Infertility, Female
Endometrial Compaction in Assissted Reproduction
To record the dynamic change of endometrial thickness (Day of embryo transfer Versus. Day of ovulation trigger administration in case of fresh cycles or end of estrogen phase in frozen cycles), and to investigate the impact of…
- Trial name
- NCT04962789
- Testing
- transvaginal ultrasound on the uterus
- Where
- Egypt
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Assiut University
Infertility, Miscarriage
Ism1 Versus EmbryoGen Media for Embryo Culture in Previous Pregnancy Loss Cases
Recently, it has been suggested that culture of embryos in EmbryoGen medium can increase the live birth rate in IVF patients with a previous history of pregnancy loss.
- Trial name
- NCT01689428
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Biogenesi
Subfertility
A RCT on the Effect of Endometrial Injury on Improving Ongoing Pregnancy Rate in Subfertile Women Undergoing FET Cycles
This is a randomised controlled trial on the effect of endometrial injury in the cycle preceding the frozen-thawed embryo transfer (FET) cycles.
- Trial name
- NCT02197832
- Testing
- Endometrial biopsy, control procedure, Pipelle catheter (Pipelle de Cornier, Laboratoire C.C.D., France)
- Where
- Hong Kong
- Volunteers
- 20 people
- Sponsor
- The University of Hong Kong
Subfertility
RCT on the Effect of Endometrial Injury on Ongoing Pregnancy Rate in Subfertile Women Undergoing IVF
Implantation failure remains one of the major factors limiting success in IVF treatment. It was postulated that the local injury to endometrium induces secretions of cytokines and growth factors such as leukemia inhibitory…
- Trial name
- NCT01977976
- Testing
- Endometrial aspiration by pipelle
- Where
- Hong Kong
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Infertility
Comparing the Ongoing Pregnancy Rate for Vitrification of Day-4 Morula With Day-5 Blast
Comparing the vitrification at Day-4 (morula stage) with the blastocyst stage vitrification outcomes with the transfer of all day 5 after warming seems need evaluation.
- Trial name
- NCT03787901
- Testing
- Morula Vitrification
- Where
- 4 sites in Egypt
- Volunteers
- 53 people
- Sponsor
- Egyptian Foundation of Reproductive Endocrinology
Embryo Transfer in Poor Responders
Comparative Study to Assess the Ongoing Pregnancy Rate for Poor Responders Women Undergoing Different Embryo Transfer Protocols
Published data on sequential transfer are limited and are not consistent. Also, further research into methods of risk combination and assessment, would allow us to help our patients make better-informed decisions about whether or…
- Trial name
- NCT05014867
- Testing
- Embryo transfer method
- Where
- Egypt
- Volunteers
- 291 people
- Sponsor
- Wael Elbanna Clinic