Clinical trials: Only Child
Atopic Dermatitis
Delgocitinib Cream for the Treatment of Moderate to Severe Atopic Dermatitis During 8 Weeks in Adults, Adolescents, and Children
This is a multi-center, open-label trial to evaluate safety and pharmacokinetics of topical delgocitinib cream applied to pediatric subjects (2-17 years) and adult subjects (18 years and above) with atopic dermatitis.
- Trial name
- NCT03826901
- Testing
- delgocitinib
- Where
- 16 sites in United States, Canada
- Volunteers
- 46 people
- Sponsor
- LEO Pharma
Autistic Children With Sensory Processing Abnormalities
Comparison of Effectiveness of Home Based Sensory Interventions Along With Standard Therapy Versus Standard Therapy Alone in Autistic Children With Sensory Processing Abnormalities
Around 69-95% of children with Autistic Spectrum Disorder are known to have sensory processing abnormalities .Tackling these problems would help in better quality of life, both for the parents and the children.
- Trial name
- NCT02491645
- Testing
- Sensory interventions
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Asthma
Study to Assess the Efficacy of Ipratropium Bromide Associated With High Dose Salbutamol by Repeated Nebulisation Versus Repeat Nebulisation of Salbutamol Alone, in Acute Asthmatic Attacks in Young Children
To determine whether addition of ipratropium bromide to salbutamol nebulisations produces significantly greater bronchodilation in young children presenting to an emergency department with an acute attack of asthma
- Trial name
- NCT02235428
- Testing
- Ipratropium bromide, Salbutamol
- Volunteers
- 3 people
- Sponsor
- Boehringer Ingelheim
Pain, Acute, Anxiety
The Effects of Finger Puppet, Abeslang Puzzle, and Pinwheel on Pain and Anxiety During Blood Sampling Procedures
Blood sampling is an invasive, diagnostic, and therapeutic procedure for children. The inability of preschool children to differentiate between reality and imagination and their belief in the power of their thoughts make it…
- Conditions
- Pain, Acute, Anxiety, Child, Only
- Trial name
- NCT05904483
- Testing
- PFA
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Bartın Unıversity
HIV Infections
Antiviral Responses to NNRTI-Based vs. PI-Based ARV Therapy in HIV Infected Infants Who Have or Have Not Received Single Dose NVP for Prevention of Mother-to-Child Transmission of HIV
A single dose of nevirapine (SD NVP) given to an HIV infected pregnant woman followed by a single dose to her infant has been shown to be an effective way of reducing the risk of mother-to-child transmission (MTCT) of HIV.
- Trial name
- P1060 (NCT00307151)
- Testing
- Lamivudine, Lopinavir/ritonavir, Nevirapine
- Where
- 10 sites in India, Malawi and 5 more
- Volunteers
- 452 people
- Sponsor
- International Maternal Pediatric Adolescent AIDS Clinical Trials Group
Cough Severity, Cough Frequency
Clinical Trial Evaluate the Cough-relieving and Expectorant Effects of the Health Supplement AZKA Nasal and Throat for Children in Outpatient-treated Pharyngitis
This is a randomized, open-label, single-center clinical trial evaluating the efficacy and safety of Azka Nasal and Throat for Children compared to the control drug Prospan Cough Syrup in children aged 4-6 years diagnosed with…
- Conditions
- Cough Severity, Cough Frequency, Cough Duration, Phlegm Accumulation (Nasal and Throat Mucus)
- Trial name
- AZKA (NCT06761339)
- Testing
- Azka Nasal and Throat for Children, Prospan cough Syrup
- Where
- Vietnam
- Volunteers
- 24 people
- Sponsor
- Haiphong University of Medicine and Pharmacy
Sleep Problems
Assessment of the Pharmacokinetics of Circadin® in Children With Neurodevelopmental Disorders and Sleep Disturbances
There is increasing evidence that chronic sleep disorders in children with autism spectrum disorder (ASD), Angelman Syndrome (AS) and Smith-Magenis syndrome (SMS) are associated with disturbed melatonin secretion and melatonin…
- Trial name
- NCT01903681
- Testing
- Circadin 2 mg, Circadin 10 mg
- Where
- Netherlands
- Volunteers
- 16 people
- Sponsor
- Neurim Pharmaceuticals Ltd.
Breathing Techniques, Asthma Control Level
Effects of Buteyko Breathing Exercise in Children With Uncontrolled Asthma
This randomized controlled trial study aimed to measure the effectiveness of the combination of 4-weeks Buteyko breathing exercises and pharmacological therapy compared with pharmacological therapy alone in children with…
- Conditions
- Breathing Techniques, Asthma Control Level, Asthma in Children, Asthma Patients
- Trial name
- NCT07025616
- Testing
- Buteyko, Asthma reliever and controller
- Where
- Indonesia
- Volunteers
- 74 people
- Sponsor
- Ivan Sofian Wibowo
Influenza
The Objectives of This Study Are Comparative Assessment of the Tolerability, Safety and Immunogenicity of the Flu-M Vaccine vs. the Ultrix® Vaccine by Single Vaccination of Children Aged 6 to 17 Years.
Comparative assessment of the tolerability, safety and immunogenicity of the Flu-M vaccine vs. the Ultrix® vaccine by single vaccination of children aged 6 to 17 years.
- Trial name
- NCT05317767
- Testing
- Flu-M [Inactivated split influenza vaccine], Inactivated Split Influenza Vaccine
- Where
- 2 sites in Russia
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- St. Petersburg Research Institute of Vaccines and Sera
HIV-1
A Study to Evaluate the Pharmacokinetics, Safety, Tolerability, and Antiviral Activity of Rilpivirine (TMC278) in Human Immunodeficiency Virus Infected Adolescents and Children Aged Greater Than or Equal to 6 Years
The purpose of this study is to evaluate the pharmacokinetics, safety and antiviral activity of rilpivirine (TMC278) 25 milligram (mg) or adjusted dose once daily in combination with an investigator-selected background regimen…
- Trial name
- NCT00799864
- Testing
- Rilpivirine, Zidovudine, Abacavir
- Where
- 17 sites in United States, India and 6 more
- Volunteers
- 54 people
- Sponsor
- Janssen Sciences Ireland UC
Pain, Assessment, Self
Validation of Pain Assessment Scale Faces Thermometer Scale (FTS)
The aim of the study was to psychometrically evaluate the electronic self assessment Faces Pain Scale (FPS). Validation is performed in relation to golden standard of pain scale assessments Faces Pain Scale Reversed (FPS-R) and…
- Conditions
- Pain, Assessment, Self, Child, Only
- Trial name
- NCT05329467
- Testing
- Validation of Faces Thermomether Scale
- Where
- 2 sites in Sweden
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Lund University
Gait Disorders, Neurologic, Cerebral Palsy
Feasibility of the Overground Bodyweight Supporting Walking System Andago
The overall aim of this project is to investigate the clinical utility of the Andago System, a CE certified mobile bodyweight supporting walking robot, in children with neuromotor disorders.
- Conditions
- Gait Disorders, Neurologic, Cerebral Palsy, Stroke, Traumatic Brain Injury
- Trial name
- NCT03787199
- Testing
- Andago, Treadmill
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- University Children's Hospital, Zurich
Reduce Pain After Herniorrhaphy
Effectiveness of Single Paravertebral Blockade Injection for Herniorrhaphy in Children
Paravertebral block (PVB) might be a technique of choice for hernia surgery due to its unilateral segmental anesthesia of the operative site, good muscle relaxation and prolonged postoperative analgesia.
- Trial name
- NCT02984800
- Testing
- Anesthesia induction, PVB injection at L1-L2, PVB injections at T12-L1, L1-L2 and L2-L3.
- Where
- Lebanon
- Volunteers
- 100 people
- Sponsor
- Makassed General Hospital
Advanced Hepatocellular Carcinoma
Durvalumab and Tremelimumab as First Line Treatment in Participants With Advanced Hepatocellular Carcinoma (HCC)
This study will assess the safety and efficacy of Single Tremelimumab Regular Interval Durvalumab (STRIDE) as first-line therapy in participants with advanced unresectable HCC.
- Trial name
- SIERRA (NCT05883644)
- Testing
- Durvalumab, Tremelimumab
- Where
- 40 sites in United States, France and 8 more
- Volunteers
- 111 people
- Sponsor
- AstraZeneca
Plasmodium Falciparum Infection
To Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of a Single Dose Regimen of Ferroquine and Artefenomel in Adults and Children With Uncomplicated Plasmodium Falciparum Malaria
Primary Objective: To determine whether a single dose combination of OZ439 (Artefenomel)/FQ (Ferroquine) was an efficacious treatment for uncomplicated Plasmodium falciparum malaria in adults and children.
- Trial name
- FALCI (NCT02497612)
- Testing
- Ferroquine SSR97193, Artefenomel
- Where
- 12 sites in Benin, Burkina Faso and 5 more
- Volunteers
- 377 people
- Sponsor
- Sanofi
Heart Disease
Sildenafil in Single Ventricle Patients
Patients with single ventricle anatomy undergo staged surgical palliation. The result is an "in series" circulation with pulmonary blood flow and cardiac output directly related to pulmonary vascular resistance.
- Trial name
- NCT01169519
- Testing
- Sildenafil by injection
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Duke University
Leiomyoma
Effect of Hepatic Impairment on the Pharmacokinetics, Safety and Tolerability of BAY1002670 (Vilaprisan)
Evaluate the potential effect of hepatic impairment on the pharmacokinetics, safety and tolerability of BAY1002670 (vilaprisan)
- Trial name
- NCT03092999
- Testing
- Vilaprisan (BAY1002670)
- Where
- 2 sites in Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Bayer
Nutrition Disorder, Child
Randomized One-Center Controlled Trial on a Comprehensive Nutritional Intervention for Children With Cerebral Palsy and ASD
The study is a prospective, single-center, randomized controlled trial that will be conducted at the Medical University of Varna.
- Trial name
- Nutrilect (NCT06065904)
- Testing
- Nutrilect
- Volunteers
- 200 people
- Sponsor
- Silviya Pavlova Nikolova, PhD
Infectious Disease, Infections
L-citrulline to Improve Adverse Outcomes in Admitted Children (EChiLiBRiST, Clinical Trial 2, Inpatients)
In low and middle-income countries, children admitted to hospital are not similarly ill, and do not all have a comparable prognosis.
- Conditions
- Infectious Disease, Infections, Child, Only
- Trial name
- NCT06426147
- Testing
- L-citrulline
- Where
- 2 sites in Ethiopia, Mozambique
- Volunteers
- 2,200 people
- Sponsor
- Barcelona Institute for Global Health
Patella Dislocation Recurrent, Children, Only
Assessment of Knee Flexor Muscles Strength in Patients With Patellar Instability
The study enrolled 33 patients with confirmed recurrent patellar dislocation, including 6 patients with bilateral involvement. In the study group, both side hamstring muscle were evaluated at the velocities of 60 and 180 deg/s…
- Trial name
- NCT04838158
- Testing
- Isokinetic measurements
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Polish Mother Memorial Hospital Research Institute
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