Clinical trials: Only Child
Crohn Disease
Randomized Trial Comparing Single vs. Maintenance Fecal Microbiota Transplant for Refractory Crohn's Disease in Children
NCT02108821 Primary goal: -To determine the safety of fecal transplant by colonoscopy and retention enemas for induction followed by maintenance retention fecal vs.
- Trial name
- NCT03747718
- Testing
- Fecal Microbiota Transplantation
- Where
- United States
- Sponsor
- Stanford University
Dengue Fever With Warning Signs
Phase 3b Trial To Evaluate Safety And Immune Response (Superiority) of a Two-Dose Butantan-DV Regimen And The Standard Single Dose In Dengue-Naive Children/Adolescents and Immune Response (Non-inferiority) in a Manufacturing Facility Change (DEN-06-IB)
This randomized, double-blind, three parallel-group, multicenter, phase 3b trial evaluates the safety and immunogenicity of Butantan-DV. The study compares two primary immunization regimens (Butantan-DV/Butantan-DV vs.
- Trial name
- DEN-06-IB (NCT07712926)
- Testing
- Butantan-DV (IB), Butantan-DV (WuXi)
- Volunteers
- 1,765 people, healthy volunteers welcome
- Sponsor
- Butantan Institute
Acute Lymphoblastic Leukemia, Pediatric, ALL, Infants
Combined Immuno-chemotherapy for Patients With B-linear Acute Lymphoblastic Leukemia Diagnosed From 0 to 365 Days of Life (ALL-Baby-2021)
The innovation of this protocol is the risk-adapted choice of therapy and the use of a combination of chemotherapy with immunotherapy and hematopoietic stem cell transplantation for patients with risk factors.
- Trial name
- NCT05029531
- Testing
- the risk-adapted choice of therapy and the use of a combination of chemotherapy with immunotherapy and hematopoietic stem cell transplantation for patients with risk factors.
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- Federal Research Institute of Pediatric Hematology, Oncology and Immunology
Parents, Burnout
Prevalence of Parental Burnout Among Mothers of Children With Cerebral Palsy
This study will be done to determine the prevalence of Parental Burnout among mothers of children with cerebral palsy. Determine the relation between Parental Burnout syndrome and the motor function levels of children with…
- Conditions
- Parents, Burnout, Children, Only, Cerebral Palsy
- Trial name
- NCT06572137
- Where
- Egypt
- Volunteers
- 380 people
- Sponsor
- Cairo University
Pain, Child, Only
The Effect Of Use Of Raınstick And Kaleydoscope On Paın Anxıety Durıng Blood Draw
Medical procedures are negative experiences that cause pain, distress, and anxiety and are not only uncomfortable during medical procedures, especially in children; negative consequences such as poor recovery, sleep disturbances…
- Conditions
- Pain, Child, Only, Anxiety, Pain, Procedural
- Trial name
- NCT05288309
- Testing
- RAINSTİCK, KALEİDOSCOPE
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Erzincan Binali Yildirim Universitesi
Diabetes Mellitus, Type 1, Disordered Eating
Parent Intervention to Prevent Disordered Eating in Children With Type 1 Diabetes
A recent Diabetes UK Position Statement identified several key gaps in the evidence base that might improve mental wellbeing for people with diabetes; one of which was supporting people with diabetes and eating disorders.
- Conditions
- Diabetes Mellitus, Type 1, Disordered Eating, Children, Only, Eating Disorders
- Trial name
- PRIORITY (NCT04741568)
- Testing
- Parental psychoeducational Intervention
- Where
- 3 sites in United Kingdom
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Nutrition Disorder, Child
Randomized One-Center Controlled Trial on a Comprehensive Nutritional Intervention for Children With Cerebral Palsy and ASD
The study is a prospective, single-center, randomized controlled trial that will be conducted at the Medical University of Varna.
- Trial name
- Nutrilect (NCT06065904)
- Testing
- Nutrilect
- Volunteers
- 200 people
- Sponsor
- Silviya Pavlova Nikolova, PhD
Atopic Dermatitis
Wearable Skin Sensors to Assess Nocturnal Scratch Behavior
Pilot study of flexible and wearable sensor to monitor nocturnal scratching behavior
- Trial name
- NCT03770858
- Testing
- Crisaborole, Scratch sensor
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pediatric Disorder, Disability, Developmental
Hybrid Telehealth in Pediatric Physical Therapy
The purposes of this study are to compare the impact of a hybrid of telehealth and in-person physical therapy services to in-person services alone on the in-home functional skills of children with moderate to severe disability.
- Trial name
- NCT05350904
- Testing
- Hybrid of telehealth and in-person physical therapy services
- Where
- United States
- Sponsor
- University of Missouri-Columbia
Hypoxemia
POM vs HFNC for Hypoxemia Prevention in Children
Upper gastrointestinal endoscopy is a commonly performed diagnostic and therapeutic procedure in children, allowing evaluation of the esophagus, stomach, and duodenum, as well as interventions such as biopsy, foreign body…
- Trial name
- NCT07234188
- Testing
- Procedural Oxygen Mask, High-Flow Nasal Cannula
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bedirhan Günel
RSV Infection, Children, Only
RSV Burden in Outpatient and Hospital Settings
Strengthening outpatient low respiratory tract infection surveillance to document the burden of Respiratory Syncytial Virus (RSV)
- Conditions
- RSV Infection, Children, Only, Outpatient, Otitis
- Trial name
- Oursyn (NCT04743609)
- Testing
- nasopharyngeal samples
- Where
- France
- Volunteers
- 1,900 people
- Sponsor
- Association Clinique Thérapeutique Infantile du val de Marne
Hepatic Impairment
A Trial to Evaluate the Pharmacokinetics of ABL001 in Healthy and Hepatic Impaired Subjects
The main purpose of this study is to evaluate the effect of varying degrees of impaired hepatic function (by Child-Pugh classification) on the pharmacokinetics (PK) of ABL001 after a single oral dose.
- Trial name
- NCT02857868
- Testing
- ABL001
- Where
- 3 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Autism Spectrum Disorder, Autism
Vancomycin and Fecal Microbiota Transplant in a Single Patient With Autism Spectrum Disorder
Single patient with ASD will be treated with Vancomycin followed by FMT.
- Trial name
- NCT04878718
- Testing
- Fecal Microbiota Transplant; Vancomycin
- Where
- United States
- Sponsor
- ProgenaBiome
Pain, Acute, Child, Only
Use of the Equimolar Mixture of Oxide Nitrous and Oxygen (EMONO) Associated With Audiovisuals in Children
Children experience numerous painful experiences from nursing procedures: peripheral venous access placement is the main cause of procedural pain.
- Conditions
- Pain, Acute, Child, Only, Nurse's Role, Nitrous Oxide
- Trial name
- EMONO (NCT05435118)
- Testing
- EMONO + audiovisuals tool
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Azienda Socio Sanitaria Territoriale di Lodi
Pain
A Study to Evaluate Ibuprofen (IBU) 62.5 mg and Acetaminophen (APAP) 125 mg/5 ml in an Oral Liquid Suspension Fixed-Dose Combination Product in Children Aged 6 to 11 Years
The purpose of this study will be to characterize the pharmacokinetic (PK) profile of the Fixed-Dose Combination (FDC) IBU 62.5 milligram (mg)/APAP 125 mg per 5 milliliter (mL) suspension in children 6 to 11 years of age…
- Trial name
- NCT07632274
- Testing
- Test Product
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- HALEON
Obstructive Sleep Apnea of Child
Single Cell Sequencing of Tonsillar Tissue in Children With OSA
Obstructive sleep apnoea (OSA) in children is a prevalent sleep disorder, and is characterised by repetitive complete or partial upper airway obstruction during sleep.
- Trial name
- NCT05115968
- Testing
- Tonsillectomy
- Where
- Hong Kong
- Volunteers
- 16 people
- Sponsor
- Chinese University of Hong Kong
Healthy
Pharmacokinetics of Nilotinib in Subjects With Impaired Hepatic Function and Healthy Subjects With Normal Hepatic Function
This study will be a formal assessment of the impact of hepatic function impairment on the pharmacokinetics of nilotinib
- Trial name
- NCT00418626
- Testing
- Nilotinib
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Achondroplasia
A Study to Evaluate the Efficacy and Safety of Recombinant Human Growth Hormone in Children With Achondroplasia
To Evaluate the Efficacy and Safety of Recombinant Human Growth Hormone in Children with Achondroplasia
- Trial name
- NCT05353192
- Testing
- Recombinant human growth hormone
- Where
- China
- Volunteers
- 39 people
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Leukemia
A Study Comparing Single Versus Double Umbilical Cord Blood Transplantation in the Young With Acute Leukemia Remission
Unrelated cord blood transplantation (UCBT) has been used for several years when there is no HLA identical sibling or unrelated donor.Since the recent publication of encouraging results after transplantation of two UCB units, the…
- Trial name
- NCT01067300
- Testing
- Transplantation of unrelated cord blood unit(s)
- Where
- France
- Volunteers
- 198 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Reduce Pain After Herniorrhaphy
Effectiveness of Single Paravertebral Blockade Injection for Herniorrhaphy in Children
Paravertebral block (PVB) might be a technique of choice for hernia surgery due to its unilateral segmental anesthesia of the operative site, good muscle relaxation and prolonged postoperative analgesia.
- Trial name
- NCT02984800
- Testing
- Anesthesia induction, PVB injection at L1-L2, PVB injections at T12-L1, L1-L2 and L2-L3.
- Where
- Lebanon
- Volunteers
- 100 people
- Sponsor
- Makassed General Hospital
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