Clinical trials: Onychomycosis
Onychomycosis
Clinical Investigation for the Evaluation of Efficacy and Safety of Two Medical Devices for Onychomycosis Treatment
The goal of this clinical trial is to evaluate the effectiveness of FORTE, ACTIVE COVER LIGHT and Loceryl® in the treatment of onychomycosis based on the blinded evaluation of the percentage of healthy nail surface compared to…
- Trial name
- NCT06254027
- Testing
- Forte, Active Cover Light, Loceryl
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Oystershell NV
Onychomycosis
Treating Onychomychosis
A study to treat 4 toes at a time to eliminate Onychomycosis
- Trial name
- NCT00776464
- Testing
- Noveon laser
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Nomir Medical Technologies
Onychomychosis
Comparative Study Between Pulsed and Continuous Itraconazole for the Treatment of Onychomycosis
The term onychomycosis is used for a chronic fungal infection of the nail which when caused by dermatophytes, becomes tinea unguium. It not only includes the dermatophytes but also saprophytic molds infections and yeasts.
- Trial name
- NCT05567484
- Testing
- Itraconazole
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Combined Military Hospital Abbottabad
Onychomycosis
Optimizing the Treatment of Toenail Onychomycosis Using a New Transdermal Patch Combined With Terbinafine/Ketoconazole
This study is to explore the optimization of anti-onychomycosis patch with various formulation contents (three patch groups: 3%, 6% and 8% of terbinafine (contains 3-mg, 6-mg and 8-mg/patch terbinafine, respectively) combined…
- Trial name
- NCT01615913
- Testing
- 3 mg terbinafine and 2 mg ketoconazole containing patch, 6 mg terbinafine and 2 mg ketoconazole containing patch, 8 mg terbinafine and 2 mg ketoconazole containing patch
- Where
- Taiwan
- Volunteers
- 18 people
- Sponsor
- Taiwan Biotech Co., Ltd.
Distal Subungual Onychomycosis
A Multi-centre, Double-blind, Randomized, Vehicle-controlled Study of Efficacy and Safety of Topical MOB015B in the Treatment of Mild to Moderate Distal Subungual Onychomycosis (DSO)
The primary objective of this study is to evaluate the efficacy of topical MOB015B in patients with mild to moderate distal subungual onychomycosis (DSO).
- Trial name
- NCT02859519
- Testing
- MOB015B, MOB015B Vehicle
- Where
- 10 sites in United States, Canada
- Volunteers
- 365 people
- Sponsor
- Moberg Pharma AB
Hyperthermia
Infrared Bioeffect System for the Treatment of Onychomycosis
Onychomycosis is a common nail plate infection caused by dermatophytes, non-dermatophytic molds, and yeasts. The disease is difficult to achieve self-healing and predisposed to secondary bacterial infections.
- Trial name
- NCT06036654
- Testing
- infrared thermotherapy instrument
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gao Xinghua
Onychomycosis Due to Trichophyton Rubrum, Onychomycosis Due to Trichophyton Mentagrophytes
Early Feasibility Study to Evaluate the Efficacy and Safety of the RenewalNail™ Plasma Treatment System in Patients With Mild to Moderate Onychomycosis (Fungal Nail)
Early feasibility study to determine if a three-treatment protocol with the RenewalNail™ plasma treatment system over a week will result in mycological cure and/or clear nail growth on the treated hallux toe.
- Trial name
- NCT03072550
- Testing
- RenewalNail™ Plasma Treatment System
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- DeviceFarm, Inc.
Onychomycosis of Toenail
An Internet Mediated Research Study to Assess the Quality of Life of Consumers With Self-reported Fungal Nail Infection (Onychomycosis) During Treatment With Scholl Fungal Nail.
To evaluate the effect on quality of life of consumers with self-reported onychomycosis during the first 4 weeks of treatment in relation to the appearance of the infected toenail.
- Trial name
- NCT04084782
- Testing
- Fungal Nail Treatment Kit
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Distal Subungual Onychomycosis, Fungal Infection
A Trial Involving Treatment of BB2603 in Subjects With Distal Subungual Onychomycosis of the Toenail
This study will be a multicenter, international, randomized, vehicle-controlled, parallel-group, double-blinded study. Subjects who are eligible to participate with a confirmed diagnosis of Distal Subungual onychomycosis (DSO) of…
- Conditions
- Distal Subungual Onychomycosis, Fungal Infection, Fungus, Nail
- Trial name
- NCT04188574
- Testing
- BB2603-1, BB2603-3, BB2603-10
- Where
- 20 sites in Czechia, Germany and 1 more
- Volunteers
- 111 people
- Sponsor
- Blueberry Therapeutics
Onychomycosis
Safety and Efficacy of NVXT Solution in Mild-to-Moderate Fungal Infection of the Toe Nail
This study will examine the safety, tolerability and efficacy of NVXT in a new formulation in patients with mild-to-moderate fungal infection of the toe nail.
- Trial name
- NCT02343627
- Testing
- NVXT Solution, Vehicle of test product
- Volunteers
- 47 people
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Onychomycosis of Toenail
A Phase 2 Study to Assess the Effectiveness of Topical Terbinafine in Participants With Mild to Moderate Onychomycosis of the Toenails
Onychomycosis is a fungal infection of the toenail caused by a range of organisms, including dermophytes, non-dermophyte molds, and yeasts.
- Trial name
- NCT07382427
- Testing
- 2.4% Topical Terbinafine, 10% Topical Efinaconazole, Vehicle Control
- Volunteers
- 200 people
- Sponsor
- Onyx Axiom
Onychomycosis
A Trial to Evaluate the Safety and Efficacy of DBI-001 Gel, DBI-002 Gel, and Aqueous Gel in Subjects With Onychomycosis
This is a randomized, observer-blinded, Aqueous Gel-controlled trial examining the safety and efficacy of daily application of DBI-001 Gel vs. DBI-002 Gel vs. Aqueous Gel for 24 consecutive weeks in subjects with onychomycosis.
- Trial name
- NCT05491603
- Testing
- DBI-001, DBI-002, Aqueous Gel
- Where
- 5 sites in United States
- Volunteers
- 60 people
- Sponsor
- DermBiont, Inc.
Onychomycosis
Cumulative Irritation Test
The purpose of this study is to determine the cumulative irritation potential of the products listed by the Sponsor.
- Trial name
- NCT00680095
- Testing
- AN2690, AN2690 Solution, Vehicle, Sodium Lauryl Sulfate, 0.5%
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Pfizer
Diabetes Mellitus, Type 2, Onychomycosis
Laser Treatment for Onychomycosis in Diabetes
Fungal infections of the toe affect one in three people with diabetes. Current treatments for fungal toe infections include oral medications, but these drugs often interact with other common medications.
- Trial name
- NCT02019446
- Testing
- Laser Treatment YAG laser, Standard Treatment (control group) terbinafine hydrochloride tablets
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- BCDiabetes.Ca
Onychomycosis
Safety and Efficacy Study of Subjects With Onychomycosis of the Great Toenail
The purpose of the study is to determine the safety and efficacy of 5.0% AN2690 Solution in the treatment of distal, subungual onychomycosis of the great target toenail.
- Trial name
- NCT01278394
- Testing
- AN2690 Solution, 5.0%
- Where
- 2 sites in Mexico
- Volunteers
- 29 people
- Sponsor
- Pfizer
Onychomycosis
Absorption and Systemic Study of AN2690 in Patients With Moderate to Severe Onychomycosis (ADME I)
The purpose of the study is to determine the absorption, systemic pharmacokinetics and accumulation in the nail of AN2690 during a 28 day period of daily application of a 7.5% solution of AN2690 to all 10 toenails of up to 25…
- Trial name
- NCT00680160
- Testing
- AN2690
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Pfizer
Onychomycosis
Effectiveness and Safety of Nailner Brush 2in1 in Onychomycosis
Evaluate the effectiveness of Nailner Brush 2-in-1 in the treatment of onychomycosis based on the blinded evaluation of the percentage of healthy nail surface after 6 months of treatment compared to baseline.
- Trial name
- NCT05560841
- Testing
- topical treatment
- Where
- 2 sites in Tunisia
- Volunteers
- 50 people
- Sponsor
- Karo Pharma AB
Onychomycosis
Using Light Therapy to Treat Toe Nail Fungus
To see if four sessions of light therapy successfully treats nail fungus.
- Trial name
- NCT00771732
- Testing
- light therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Nomir Medical Technologies
Onychomycosis
Alpha-bisabolol for Onychomycosis Treatment
Clinical, interventional, longitudinal study with random sampling. 60 patients will be divided into three groups, group A: control group, drug recommended by the Brazilian Society of Dermatology, group B: alpha bisabolol-based…
- Trial name
- NCT04940520
- Testing
- Drug recommended by the Brazilian Society of Dermatology, Alpha bisabolol product and laser, Alpha bisabolol product
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Universidade do Vale do Sapucai
Onychomycosis
CLINICAL INVESTIGATION FOR THE EVALUATION OF EFFICACY AND SAFETY OF TWO PRODUCTS FOR THE TREATMENT OF ONYCHOMYCOSIS
The efficacy and safety of ENRICHED (X92001591) will be evaluated in a multicentric, randomized, evaluator blinded clinical investigation in 88 patients.
- Trial name
- NCT06689852
- Testing
- Enriched, Loceryl 5%
- Where
- France
- Volunteers
- 88 people
- Sponsor
- Oystershell NV