Clinical trials: Oocyte
Polycystic Ovary Syndrome
Myo-Inositol for Ovarian Stimulation and ICSI Outcomes in Women With PCOS
Polycystic ovary syndrome (PCOS) is a common endocrine disorder that may affect ovarian function, insulin sensitivity, and fertility.
- Trial name
- NCT07779850
- Testing
- Myo-Inositol, Folic Acid
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Kafrelsheikh University
Infertility, Female, ART
Effects of Low LH Serum Levels on Ovarian Pick-up Outcome
Luteinizing hormone (LH) plays a key role for normal follicular development and oocyte maturation in controlled ovarian stimulation.
- Trial name
- NCT05755529
- Volunteers
- 43 people
- Sponsor
- University of Palermo
Fertility
Oocyte Cryopreservation
The purpose of this investigation is to offer the opportunity for young women to cryopreserve (freeze) their oocytes (eggs) for use with IVF at a later point in time.
- Trial name
- egg freezing (NCT01232972)
- Testing
- vitrification of oocytes
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Subfertility
Evaluation of the Optimal Dose of GnRH Agonist for Triggering Final Oocyte Maturation in High Risk OHSS Patients
The present study aims to investigate whether the dosage of the GnRH agonist used for triggering final oocyte maturation affects the maturity of the oocytes retrieved in high risk for OHSS patients undergoing ovarian stimulation…
- Trial name
- ATD (NCT01973842)
- Testing
- 0.1 mg triptorelin, 0.2 mg triptorelin, 0.4 mg triptorelin
- Where
- 2 sites in Greece
- Volunteers
- 90 people
- Sponsor
- Aristotle University Of Thessaloniki
Fertilization in Vitro
Interest of Audiovisual Distraction in the Management of Anxiety and Pain During Oocyte Retrieval
Oocyte retrieval procedure for in vitro fertilization is a source of anxiety for patients. Local anaesthesia or sedation are commonly used to manage many situations of anxiety, including the oocyte retrieval.
- Trial name
- Happy-Fiv (NCT04213781)
- Testing
- HappyMed Video Glasses, Propofol, Sufentanil
- Where
- France
- Volunteers
- 36 people
- Sponsor
- CMC Ambroise Paré
Infertility
Comparison Between Recombinant Versus Urinary hCG for Ovulation Induction in High Responders
The purpose of this study is to compare the clinical outcomes of recombinant human chorionic gonadotrophin (rHCG) and urinary HCG (uHCG) in patients undergoing IVF cycles.
- Trial name
- NCT00415766
- Testing
- rHCG 250ug, uHCG 5000 IU, uHCG 7500 IU
- Where
- Greece
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Eugonia
Ovulation Induction, In Vitro Fertilization (IVF)
Agonist Versus Classical HCG Trigger (Poor Responders, Normoresponders and High Responders)
Agonist triggering in controlled ovarian stimulation protocols is being used during last years (among high responder patients to avoid OHSS). Indeed, agonist triggering is more physiologic than HCG triggering.
- Conditions
- Ovulation Induction, In Vitro Fertilization (IVF), Infertility, Female, Oocytes
- Trial name
- NCT03307720
- Testing
- Gonadotropin Releasing Hormone Agonists (GNRH-A), Human chorionic gonadotropin
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Ginegorama S.L.
Infertility
DUOSTIM and AI: is There a Difference Between Oocyte Performance in the Follicular and Luteal Phases?
In vitro fertilization (IVF) has revolutionized assisted reproductive techniques, bringing hope to thousands of people seeking to fulfill their dream of parenthood.
- Trial name
- NCT06799598
- Where
- Brazil
- Volunteers
- 92 people
- Sponsor
- Rio de Janeiro State University
Infertility
Identifying Expression Markers of Cumulus Cells to Identify Oocyte Developmental Potential Through a Maturation Analysis
The aim of the study is to analyze the expression of genes and microRNAs potentially involved in oocyte competence in follicles of different sizes (<17mm and ≥17mm) at the time of oocyte pick-up.
- Trial name
- NCT02230449
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Memorial Sisli Hospital, Istanbul
Fertility Preservation
Correlation of Oxidative Stress and Oocyte Quality in Fertility Preservation
Whether it is for oncology or personal reasons, fertility preservation allows participants to preserve their oocytes (eggs) at their current age and condition for a better chance of having a baby in the future.
- Trial name
- Ooxyd (NCT05372549)
- Testing
- Oxidative stress, cf-DNA, MAGENTA AI
- Where
- 3 sites in Canada
- Volunteers
- 179 people
- Sponsor
- Clinique Ovo
Oocyte Fertilization
Artificial Oocyte Activation Comparing Tow Different Agents
Comparing the efficacy of tow factors for artificial Oocyte Activation for poor quality Oocytes and Teratozoospermia patients.
- Trial name
- NCT02424214
- Testing
- Artificial Oocyte activation, Ca Ionophore, Strontium Chloride
- Where
- 3 sites in Bahrain, Egypt
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Ibn Sina Hospital
Infertility
Influence of a Prematuration Culture With a Phosphodiesterase-3 Inhibitor (PDE3-I) on Embryonic Aneuploidy Rate and Developmental Potential
A single centre randomised controlled trial investigating the influence of a novel prematuration system (PMS) using a phosphodiesterase-3 inhibitor for in-vitro maturation of oocytes
- Trial name
- NCT00823420
- Testing
- prematuration culture
- Where
- Belgium
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Infertility, Female, Deferred Childbearing
Investigational Oocyte Cryopreservation for Medical and Non Medical Indications
This is a prospective study to assess the long term benefits and outcomes of the existing oocyte cryopreservation methods for fertility preservation in women with a potential medical or non medical risk of loss of fertility
- Trial name
- NCT04616417
- Testing
- Investigational Oocyte Cryopreservation
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Oocyte Donation
Corifollitropin Alfa on D5 Versus D7 After Contraceptive Pill
To evaluate if the administration of corifollitropin alfa on day 7 instead of on day 5 after pre-treatment with oral contraceptive pill results in a reduced total rFSH (recombinant follicle stimulating hormone ) consumption in a…
- Trial name
- NCT02490150
- Testing
- Corifollitropin alfa
- Where
- Spain
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Fundacion Dexeus
Ovarian Hyperstimulation Syndrome, Infertility Drugs
Transfer of Fresh Versus Frozen/Thawed Embryos in IVF Cycles Where GnRH Agonist is Utilized for Oocyte Maturation.
It has been suggested that in IVF cycles where GNRH agonist is utilized for final oocyte maturation in patients at risk of ovarian hyperstimulation, pregnancy rates are reduced.
- Conditions
- Ovarian Hyperstimulation Syndrome, Infertility Drugs, Female
- Trial name
- NCT00365027
- Testing
- Delayed embryo transfer
- Sponsor
- HaEmek Medical Center, Israel
Infertility, COVID
Detection of SARS-CoV-2 in Follicular Fluid and Cumulus-oocyte-complexes in COVID-19 Patients
Recently, the world was shaken awake by a pandemic caused by a novel coronavirus SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2).
- Conditions
- Infertility, COVID, IVF
- Trial name
- COVID_OFF (NCT04425317)
- Testing
- Blood sample
- Where
- Belgium
- Volunteers
- 16 people
- Sponsor
- CRG UZ Brussel
Infertility, Infertility, Male
Scanning the Meiotic Spindle in Assisted Reproductive Techniques to Assess Oocyte Quality
The assisted reproduction success rate is affected by several factors including the age of the women, oocyte quality and maturation state, as well as sperm quality.
- Conditions
- Infertility, Infertility, Male, Infertility, Female
- Trial name
- SMART (NCT06539585)
- Testing
- Meiotic spindle status observation in polarized light, ICSI
- Where
- Czechia
- Volunteers
- 164 people
- Sponsor
- Charles University, Czech Republic
Pain, Postoperative, IVF
OPU-LUX: Virtual Reality for Pain and Anxiety Management During Oocyte Pick-up
In vitro fertilization (IVF) cycles are increasingly performed worldwide. Transvaginal oocyte pick-up (OPU) is a painful part of IVF. OPU in polyfollicular IVF is usually performed under sedation and pain relief.
- Trial name
- OPU-LUX (NCT05830513)
- Testing
- Virtual Reality
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Luzerner Kantonsspital
Ovarian Stimulation
Effect of Controlled Ovarian Stimulation in Quality of Oocyte and Embryo
Investigate and compare the efficacy of H FSH plus HMG Vs HMG alone on oocyte and embryo quality in IcsI patients
- Trial name
- NCT04539067
- Testing
- HHMG
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Minia University
Poor Ovarian Response
the Effect of Transcutaneous Electrical Acupoint Stimulation on the Quality of Oocyte on Poor Ovarian Response(POR)
Patients in experimental group will be given transcutaneous electrical acupoint stimulation (TEAS) treatment for 12 weeks prior to controlled ovarian stimulation (COS).The patients will be given three times acupuncture every week…
- Trial name
- POR (NCT03994614)
- Testing
- TEAS
- Where
- China
- Volunteers
- 92 people
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute