Clinical trials: Oocyte
Embryo Culture
Evaluating the Influence of 3D Culture Dish Design on Preimplantation Genetic Development in Sibling Oocytes: a Randomized Trial
Evaluating the Influence of 3D Culture Dish Design on Preimplantation Genetic Development in Sibling Oocytes: A Randomized Trial
- Trial name
- NCT06850909
- Testing
- Microdrop GPS dish, 16 well BIRR dish
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Ganin Fertility Center
Infertility
Study on Influence of Leutinizing Hormone (LH) on Oocyte Maturity
1. Leutinizing hormone (LH) has been demonstrated to exert variable physiological actions during menstrual cycle at appropriate plasma levels' 2.
- Trial name
- LH/M2-Oocyte (NCT01595334)
- Testing
- Cetrorelix, Luprolide Acetate
- Where
- 3 sites in India
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Southern Cross Fertility Centre
Pain, Oocyte Retrieval
Preoperative Indomethacin and Paracetamol for Pain Management During Oocyte Retrieval in IVF Patients
This is a randomized controlled trial evaluating the efficacy of preoperative analgesic medications - Indomethacin (100 mg per rectum) and Paracetamol/Acamol (1,000 mg intravenously) - for pain management during oocyte retrieval…
- Trial name
- NCT07536425
- Testing
- Indomethacin 100Mg Suppository, Paracetamol / Acetaminophen
- Where
- Israel
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Pregnancy
Once Daily vs Twice Daily Administration of Gonadotropins in Assisted Reproductive Technologies (ART)
This is a prospective randomized study evaluating dosing frequency of gonadotropin administration in ART cycles.
- Trial name
- QD vs BID (NCT00740025)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Virginia Center for Reproductive Medicine
IVF, PCOS
Single vs. Group CAPA-IVM Culture of Cumulus-oocyte Complexes
Oocyte in vitro maturation (IVM) is a minimal-stimulation ART with reduced hormone-related side effects and risks for the patients.
- Conditions
- IVF, PCOS, IVM
- Trial name
- NCT04562883
- Testing
- The way of Cumulus-oocyte complexes (COC) culture
- Where
- Vietnam
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Mỹ Đức Hospital
Polycystic Ovarian Syndrome
In-Vitro Maturation of Oocytes From Polycystic Ovarian Patients Undergoing IVF
Retrieval of immature oocytes from women with polycystic ovaries, their in-vitro maturation, fertilization and embryo transfer can prevent hormonal treatment that can lead to ovarian hyperstimulation.
- Trial name
- IVM (NCT00561808)
- Testing
- In-vitro maturation oocytes
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Oocyte Retrieval
Single Lumen Needle Without Flushing or Double Lumen Needle With Follicle Flushing in Oocyte Retrieval
The aim of this study is to compare whether oocyte flushing during retrieval is effective or not.
- Trial name
- NCT00995280
- Testing
- single lumen needle oocyte retrieval, double lumen needle oocyte retrieval
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Baskent University
Infertility, Female, Polycystic Ovary Syndrome
IVM Versus IVF: Differences in Patients' Emotional Adjustment and Quality of Life
Patients who undergo in vitro fertilization with or without intracytoplasmic sperm injection (IVF / ICSI) often experience an impact on their quality of life and emotional maladjustment to treatment and outcome.
- Conditions
- Infertility, Female, Polycystic Ovary Syndrome, Psychological Stress, Quality of Life
- Trial name
- EMAQOLIVMIVF (NCT03066349)
- Testing
- Questionnaires
- Where
- Belgium
- Volunteers
- 149 people
- Sponsor
- Universitair Ziekenhuis Brussel
Infertility, Aneuploidy
Anti-Müllerian Hormone and Embryo Aneuploidy
The goal of this observational study is to determine is there an association between the rates of aneuploidy and the different ranges of serum Antimullerian hormone (AMH) levels.
- Trial name
- NCT05723016
- Testing
- preimplantation genetic test for aneuploidies (PGT-a)
- Where
- Chile
- Volunteers
- 300 people
- Sponsor
- Clinica de la Mujer Medicina Reproductiva, Chile
Infertility
Effect of Follicle Flushing on Oocyte Fertilization Rate
The purpose of this study is to investigate the impact of follicular flushing on fertilization rate in women undergoing IVF treatment
- Trial name
- NCT03353285
- Testing
- intracytoplasmic sperm injection (ICSI)
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Eugonia
Efficiency in Terms of Mature Oocyte Yield
Optimizing Ovarian Stimulation for IVF and ICSI
Monitoring ovarian stimulation for in vitro fertilization (IVF) and intracytoplasmatic sperm injection (ICSI) can be simplified by reducing the procedure to measuring follicles by ultrasound.
- Trial name
- NCT01980563
- Testing
- ultrasound, combined monitoring
- Where
- Belgium
- Volunteers
- 416 people
- Sponsor
- University Hospital, Ghent
Progesterone Resistance
Step Down FSH Approach and Late Follicular Phase in Progesterone Level
Step-down approach and late follicular phase progesterone level
- Trial name
- FSH (NCT03356964)
- Testing
- follicle stimulating hormone
- Where
- United Arab Emirates
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Infertility
Changes in the Distribution of Mitochondria During Oocyte Maturation
Cytoplasmatic maturation is an important event in the general maturation of of the oocyte. Mitochondria is one of the major organelles involved in the process of cytoplasmatic maturation.
- Trial name
- NCT01501292
- Testing
- Fixation and staining, Observation by laser microscopy
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Hillel Yaffe Medical Center
Azoospermia, Nonobstructive
The Potential of Sperm Retrieved by Micro-TESE to Fertilize Vitrified/Warmed Oocytes
Couples referred for microdissection-TESE (m-TESE) due to Klinefelter's syndrome, maturation stop in the spermatogenesis, or failed retrieval of testicular spermatozoa by conventional techniques with needle or TruCut are…
- Trial name
- NCT03809026
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Odense University Hospital
Anesthesia, Infertility
Sevoflurane Versus Propofol; Neuro Endocrine Response in Patients of Oociyt Pick up
Patients in the study will be grouped as 1st group Propofol, 2nd Group Sevofluran.Preoperative blood will be taken from the patients and cortisol, acth, glucagon, aldosterone, PGE2, CRH will be studied.
- Conditions
- Anesthesia, Infertility, Pain, Postoperative, Stress, Psychological
- Trial name
- NCT03507621
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Yavuz Orak
Infertility
Oocyte Vitrification Aided With Cytochalasin B
Using the cytoskeleton Stabilizer the Cytochalasin B would improve the outcome of oocyte vitrification.
- Trial name
- NCT03678558
- Testing
- Cytochalasin B supplemented vitrification medium
- Where
- Egypt
- Volunteers
- 612 people
- Sponsor
- Ibn Sina Hospital
Infertility (IVF Patients)
The Effects of Carnitine Supplementation on Oocytes in Women Undergoing IVF Process
The goal of this clinical trial is to learn whether supplementation with L-carnitine improves outcomes in women undergoing in vitro fertilization (IVF).
- Trial name
- Carnitine Supp (NCT07783399)
- Testing
- L-Carnitine Group
- Where
- Serbia
- Volunteers
- 70 people
- Sponsor
- The Obstetrics and Gynaecology Clinic Narodni Front
Infertility
2D Versus SonoAVC Scanning in High Responders
Accurate follicular monitoring of Controlled Ovarian Stimulation by transvaginal ultrasound is considered important for the success of human in vitro fertilization (IVF).
- Trial name
- NCT03610009
- Testing
- 2D ultrasound, SonoAVC
- Where
- Greece
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Eugonia
Infertility, Female
Recombinant LH Prior to Ovarian Stimulation in Poor Ovarian Responders (PRE-LH)
Controlled ovarian stimulation (COS) is one of the first stages of assisted reproductive treatment. The goal is to mimic the ovarian cycle while stimulating the ovaries to overproduce eggs capable of being fertilized, thus…
- Trial name
- PRE-LH (NCT03741699)
- Testing
- Pre-treatment with rLH (Luveris 75 IU),
- Where
- 3 sites in Spain
- Volunteers
- 88 people
- Sponsor
- Instituto Valenciano de Infertilidad, IVI Alicante
Couple Sterility
Effect of Myoinositol Treatment of Spermatozoa on in Vitro Fertilization Outcome
In the present trial, the investigators aim to evaluate whether semen myo-inositol (MI) treatment is able to improve IVF outcomes.
- Trial name
- MI_ICSI (NCT02050672)
- Testing
- Myo-inositol, untreated
- Where
- Italy
- Volunteers
- 249 people
- Sponsor
- AGUNCO Obstetrics and Gynecology Centre