Clinical trials: Oocyte
Infertility
Comparison of Two Different Sedation Protocols During Transvaginal Oocyte Retrieval
The effects of two different sedation protocols during transvaginal oocyte retrieval will be investigated on propofol consumption as a rescue sedative and on IVF success.
- Trial name
- NCT03362021
- Testing
- transvaginal oocyte retrieval
- Where
- Greece
- Volunteers
- 80 people
- Sponsor
- Attikon Hospital
Infertility
Tachykinin and Kisspeptin Expression in Human Granulosa and Cumulus Cells
The purpose of this project is to study the presence of expression differences - at RNA and protein level - of different members of the tachykinin family and kisspeptin and their receptors, between fertile women and infertile…
- Trial name
- NCT02877992
- Testing
- Ovarian puncture
- Where
- 2 sites in Spain
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Vida Recoletas Sevilla
Oocyte Retrieval, Sedation, Conscious
Respiratory Depression During an Analgosedation Combining Remifentanil and Ketamine in TCI for Oocyte Retrieval
This study evaluates the effect of the addition of ketamine to a conscious sedation protocol including remifentanil during oocyte retrieval.
- Conditions
- Oocyte Retrieval, Sedation, Conscious, Ventilatory Depression
- Trial name
- NCT03458143
- Testing
- Ketamine 150 ng/ml, Remifentanil, Oocyte retrieval
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
PCOS (Polycystic Ovary Syndrome)
Optimal Allogeneic PRP Concentration for Oocyte In Vitro Maturation in Women With PCOS
In vitro maturation is a long-studied technique used to obtain mature oocytes outside the human body. However, this method can increase the risk of ovarian hyperstimulation syndrome (OHSS), particularly in patients with…
- Trial name
- NCT07514234
- Testing
- PRP plasma rich platelets
- Where
- Indonesia
- Volunteers
- 15 people
- Sponsor
- Gadjah Mada University
Infertility, Female
The Potential Effects of Inofolic Plus on Abnormal Ovarian Reserve Parameters in Subfertile Women
Dr. Roseff and his colleagues are conducting a study to evaluate the effectiveness of a novel substance (Inofolic Plus®) in improving oocyte (egg) parameters in subfertile female patients, as measured through Anti-Mullerian…
- Trial name
- NCT01290432
- Testing
- Inofolic Plus
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Palm Beach Center for Reproductive Medicine
Hypoxia, Infertility
The Efficacy of Remimazolam on Incidence of Hypoxia During Sedated Transvaginal Oocyte Retrieval
Hypoxia is the most common adverse reaction during sedation outside the operating room.Exploring novel drug combinations to reduce the incidence of hypoxia during sedation in patients undergoing transvaginal oocyte retrieval…
- Conditions
- Hypoxia, Infertility, Infertility Assisted Reproductive Technology
- Trial name
- NCT07335536
- Testing
- remimazolam-alfentanil combination, propofol-alfentanil
- Where
- 2 sites in China
- Volunteers
- 400 people
- Sponsor
- Diansan Su
Female Infertility
Establishing a Minimum Predictive Threshold Follicular Size and Oocyte Retrieval in ICSI Cycle
This study uses number and size of ovarian follicles on the day of ovulation trigger as key determinants for oocytes yield to optimize outcomes in IVF and ICSI Protocols
- Trial name
- NCT07331493
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Infertility, Pain
Pain Relief Using VR in Oocyte Retreival
Title: A randomized study on use of virtual reality technology for pain relief in transvaginal oocyte retrieval under conscious sedation Objectives: The study is to evaluate the effectiveness of virtual reality (VR) in pain…
- Trial name
- NCT05218382
- Testing
- Virtual reality, No virtual reality
- Where
- China
- Volunteers
- 160 people
- Sponsor
- The University of Hong Kong
Fertility
Effect of Oocyte Vitrification on Fertilization Rate, Embryo Quality and Development
Indications for oocyte (egg) vitrification (fast freezing) include the preservation of reproductive competence of young cancer patients who need chemotherapy, pelvic radiation, or surgical removal of ovaries for treatment.
- Trial name
- NCT01422395
- Testing
- Freezing
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Main Line Fertility Center
Polycystic Ovarian Syndrome, Infertility
Evaluation of the Mixture Myoinositol:D-chiro-inositol 3.6:1 in Women With Polycystic Ovary Syndrome
The aim of the present study is to evaluate the effect of increasing the proportion of D-chiro-inositol (DCI) in a combination with myo-inositol (MYO) in improving fertility in women with polycystic ovarian syndrome (PCOS).
- Trial name
- NCT03201601
- Testing
- D-chiro-inositol, Myoinositol
- Volunteers
- 60 people
- Sponsor
- Biosearch S.A.
Breast Cancer
Safety of Ovarian Stimulation With Letrozole and Gonadotropins in Breast Cancer Patients
Breast cancer patients are commonly treated with drugs that eggs present in the ovary and may reduce their chance for getting pregnant.
- Trial name
- NCT00504699
- Testing
- Ovarian stimulation in vitro fertilization cryopreservation
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- New York Medical College
Semen Analysis, ICSI
Evaluating the Utility of Implementing Microfluids for Sperm Preparation Compared to Conventional Method of Density Gradient Centrifugation in a PGT-A Program: a Sibling Oocyte Study
In assisted reproductive technology (ART), sperm preparation aims to select the most viable sperm for ICSI. Unlike conventional methods like density gradients or sperm washing, microfluidic techniques mimic natural selection in…
- Conditions
- Semen Analysis, ICSI, PGT-A
- Trial name
- NCT07093619
- Testing
- FERTILE Plus
- Where
- United Arab Emirates
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Infertility
Usefulness of Medroxyprogesterone Acetate in Follicular Phase in Oocyte Donors. Undergoing Ovarian Stimulation
The purpose of this study is to determine whether Medroxyprogesterone Acetate (MPA) administration in follicular phase prevents premature luteinization with equal efficiency as GnRH antagonists and otains similar clinical results…
- Trial name
- NCT03300960
- Testing
- Provera 10 mg., Ganirelix (GnRH antagonist)
- Where
- Spain
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Consumption of Anaesthetic Agents, Sedoanalgesia
Effects of Patients' Hormone Levels on Sedoanalgesia
Investigastors hypothesis is that the need for anaesthetic agents is less in patients with high progesterone levels and more in patients with high estrogen levels.
- Trial name
- NCT07378241
- Testing
- Anesthesia Maintenance
- Volunteers
- 100 people
- Sponsor
- Izmir City Hospital
Infertility, Female, IVF
MVA to Improve the Pregnancy Outcome in Aged Infertility Women With Assisted Reproductive Technology
The goal of this clinical trial is to test MVA on improving pregnancy outcome in elderly infertile patients undergoing invitro fertilization (IVF).
- Conditions
- Infertility, Female, IVF, Reproductive Disorder, Oocyte
- Trial name
- NCT05788822
- Testing
- Mevalproic acid
- Where
- China
- Volunteers
- 148 people
- Sponsor
- Nanjing University
Anxiety
The Effectiveness of Virtual Reality on Anxiety Reduction in Women Undergoing Elective Egg Cryopreservation.
A randomized trial assessing the effectiveness of virtual reality exposure prior to an oocyte retrieval procedure in terms of anxiety level .
- Trial name
- VRFORANXIETY (NCT06280222)
- Testing
- The VR instrument - Oculus Quest 2
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Infertility Primary
AOA in Recurrent Fertilization Failure
Background: Despite the high success rate of ICSI, total fertilization failure still occurs in 1-3% of all ICSI cycles and can recur in subsequent cycles, even when a sufficient number of oocytes and motile spermatozoa are…
- Trial name
- AOA (NCT04744753)
- Testing
- Calcium Ionophore A23187
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- MOHAMED BEHERY
Fertility Disorders
Dual Ovarian Stimulation (DUOSTIM) for Poor Ovarian Responders
During ovarian stimulation, all the follicles grow under the action of FSH, only the selected follicles and with the faster growth are taken.
- Trial name
- NCT03803228
- Testing
- DUOSTIM, Conventional stimuli
- Where
- 4 sites in France
- Volunteers
- 88 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Ovarian Reserve
CD133 Transplantation to Generate Oocytes in Poor Ovarian Reserve
Women delay maternity and, as a consequence, available oocyte number and their quality decrease (9-18% of all IVF patients). Different treatment protocols have been developped nevertheless none of them optimal: the number of…
- Trial name
- NCT01966536
- Testing
- CD133+ cells transplantation into ovarian artery of one ovary
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hospital Universitario La Fe
Infertility
Aurora Test for ART Donor Patients (AURORA-Donor)
This is a randomized observational study. The main aim is to determine potential oocyte competence predictive mRNA expression profiles in the cumulus cells isolated form individual oocytes.
- Trial name
- NCT06280677
- Testing
- AURORA-Donor
- Where
- Spain
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Fertiga, Belgium