Clinical trials: Oocyte
Ectopic Pregnancies
Activin A and Inhibin A in Predicting Outcome of Pregnancies of Unknown Location After Assisted Reproductive Technology
The purpose of this study is to determine the predictive value of a single serum determination of activin A and inhibin A for the prognosis of ectopic pregnancy after in Vitro Fertilization (IVF) cycles, in both native and…
- Trial name
- NCT01589016
- Where
- Spain
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Infertility
Administration of Follicle-stimulating Hormone (FSH) and Low Dose Human Chorionic Gonadotropin (hCG) for Oocyte Maturity While Decreasing hCG Exposure in In Vitro Fertilization (IVF) Cycles
This is a randomized, double-blind, single center clinical trial study to compare oocyte competence and risk of ovarian hyperstimulation syndrome (OHSS) after receiving the standard dose of human chorionic gonadotropin (hCG)…
- Trial name
- NCT02310919
- Testing
- Low dose hCG plus FSH co-trigger, Standard dose of hCG
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Poor Response to Ovulation Induction
A Prospective Observational Study of Biomarkers for a Personalised IVF Treatment
Study investigates the effect of four-dimensional patient data (medical, lifestyle, environmental, and genetic) on the outcomes of ovarian stimulation for IVF.
- Trial name
- NAITIVE (NCT05780632)
- Where
- Czechia
- Volunteers
- 500 people
- Sponsor
- Cognitive IVF a.s.
Subfertility
Comparison of the Number of Oocytes Obtained Between Chinese and Caucasian Women in IVF Treatment
IVF is a well-established method to treat various causes of infertility. Some studies have suggested that ethnicity affects the success of IVF.
- Trial name
- NCT02748278
- Testing
- Transvaginal ultrasound-guided oocyte retrieval, Embryo transfer
- Where
- China
- Volunteers
- 192 people
- Sponsor
- The University of Hong Kong
Repetition Failure
Clinical Application of Autologous Mitochondria Transplantation for Improving Oocyte Quality.
Embryo quality was ranked as one of the most important predictors in determining the success of implantation, while clinically some patients may experience repeated IVF failure due to persistent poor embryo quality.Mitochondria…
- Trial name
- NCT03639506
- Testing
- autologous mitochondria transplantation, autologous mitochondria from bone marrow mesenchymal stem cells into oocyte as well as intracytoplasmic sperm injection (ICSI), intracytoplasmic sperm injection (ICSI)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
OVARIAN STIMULATION
Follicular Volume at the Time of Final Oocyte Maturation in Poor Responders, and Its Correlation With Oocyte Maturity
Women with a severely diminished ovarian reserve and monofollicular growth are at a higher risk of premature ovulation as well as poor quality oocytes.
- Trial name
- NCT06839274
- Testing
- transvaginal Ultrasound
- Where
- United Arab Emirates
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Pregnancy, Oocyte Donation
What Are the Predictive Factors for Preeclampsia in Oocyte Recipients? - PREROVE
The main goal is to determine which risk factors develop preeclampsia in this specific group of oocyte recipients.
- Trial name
- PREROVE (NCT03668184)
- Testing
- preeclampsia
- Where
- 2 sites in France
- Volunteers
- 150 people
- Sponsor
- Rennes University Hospital
Female Infertility
Effect of Growth Hormone on Uterine Receptivity in Women With RIF in an Oocyte Donation Program
105 infertile women are enrolled in the randomized controlled trial: 70 women with a history of RIF with donated oocytes and 35 infertile women undergoing the first oocyte donation attempt.
- Trial name
- NCT03237117
- Testing
- Growth Hormone (GH)
- Where
- Spain
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Competence Centre on Health Technologies
Vascular Endothelial Growth Factor Overexpression
Differential Regulation of VEGF, Cadherin, Angiopietin 2 by Trigger Oocyte Maturation With GnRHa vs hCG in Donors
Introduction OHSS still remains a complication of assisted reproduction treatments. hCG administration to trigger final oocyte maturation will release vascular mediators, being VEGF and other proteins such as VE-Cadherin or…
- Trial name
- NCT00848185
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- IVI Madrid
Oocyte Maturation, Infertility
OSC Co-culture for Rescue IVM of Human GV Oocytes
This single-center randomized sibling-oocyte controlled trial evaluates whether co-culture with induced pluripotent stem cell (iPSC)-derived ovarian support cells (OSCs) improves rescue in vitro maturation (r-IVM) outcomes of…
- Trial name
- OSC-rIVM (NCT07559357)
- Testing
- Conventional rescue in vitro maturation, Rescue in vitro maturation with iPSC-derived ovarian support cell co-culture
- Where
- Vietnam
- Volunteers
- 102 people
- Sponsor
- Hung Vuong Hospital
Infertility, Female, Fertility Disorders
Comparison of Two PPOS Models for Pituitary Suppression
The scarcity of evidence regarding the interchangeable use of different progestogens poses challenges, particularly in international egg donation and fertility preservation programs where standardizing protocols is crucial for…
- Trial name
- NCT06304220
- Testing
- Cerazet
- Where
- Spain
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- NextFertility
Infertility
Study of Dual Trigger Ovulation in Oocyte Donors
The project is a randomized, controlled, prospective study of oocyte donors comparing the safety and efficacy of triggering ovulation using a combination of two drugs-GnRH agonist and very low dose hCG-versus triggering ovulation…
- Trial name
- DUALTRIGGER (NCT01443546)
- Testing
- HCG, Lupron Trigger, Dual Trigger
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Infertility
Oocyte Vitrification Aided With Latrunculin A
Using cytoskeleton Stabilizer the Latrunculin A would improve the outcome of oocyte vitrification
- Trial name
- NCT03678571
- Testing
- Latrunculin A supplemented vitrification medium
- Where
- 3 sites in Egypt
- Volunteers
- 400 people
- Sponsor
- Ibn Sina Hospital
Infertility, Female, Anesthesia Awareness
Preoperative Anxiety at Oocyte Retrieval
This study evaluated the effects of preoperative anxiety and dosage of anesthesia on IVF success. Half of participants according to the recorded Beck's Anxiety Inventory (BAI) score: a low-anxiety group, while the other half…
- Conditions
- Infertility, Female, Anesthesia Awareness, Anxiety State
- Trial name
- NCT03134651
- Testing
- Monitoring brain function, propofol
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Trakya University
Bacterial Vaginoses
The Temporo-spatial Dynamics of Genital Tract Microbiota - an Observational Study in Oocyte Donors
The investigators aim to examine the endometrium with state of the art sequencing techniques to investigate the endometrial microbiota.
- Trial name
- NCT04393857
- Where
- Spain
- Volunteers
- 26 people
- Sponsor
- Peter Humaidan
Fertility, In Vitro Fertilization
A Study Comparing a Shorter Exposure of Oocyte to Spermatozoa Versus a Standard Incubation on the Live Birth Rate of In-vitro Fertilization Treatment
In vitro fertilization (IVF) treatment is now commonly used to treat infertile couples. During IVF treatment, oocytes and sperm are routinely incubated overnight and this may lead to suboptimal culture conditions because of…
- Trial name
- NCT02534857
- Testing
- a shorter exposure of oocyte to spermatozoa
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
Infertility, Female
Comparison of in Vitro Fertilization Rates of Oocytes and Embryo Development Using Two Techniques of Semen Processing
The investigators propose to assess one method of sperm selection based on the characteristics of spermatozoa recently introduced: Sperm Selection Assay, which used a gradient of concentration of progesterone to act as…
- Trial name
- NCT03186170
- Testing
- SSA sperm selection
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
in Vitro Fertilization
AOA Versus Non-AOA in Low Prognosis Patients by the POSEIDON Criteria
Poor ovarian response (POR) remains one of the significant challenges of Assisted Reproductive Technology (ART). Facing difficulties related to clinical practice, optimizing the embryo culture process is necessary to improve the…
- Trial name
- NCT05402605
- Testing
- ICSI with AOA, ICSI without AOA
- Where
- Vietnam
- Volunteers
- 528 people
- Sponsor
- Mỹ Đức Hospital
Endometriosis
Influence of an Endometrioma on Oocyte Quality
The purpose of this study is to evaluate if there are differences in oocyte quality depending on whether these oocytes come from an ovary in contact with an endometrioma.
- Trial name
- ENDOVOC (NCT03352661)
- Testing
- Collect retrospectively data
- Volunteers
- 80 people
- Sponsor
- IVI Vigo
Embryo, Embryo Disorder
Genetic Screening and Assisted Oocyte Activation in Couples with Diminished/aberrant Embryonic Development.
This is an interventional comparative study at the Department of Reproductive Medicine at Ghent University Hospital. Patients with previous embryo developmental problems are eligible for the study.
- Conditions
- Embryo, Embryo Disorder, Genetic Disease
- Trial name
- AOA (NCT03354013)
- Testing
- AOA, Genetic screening, Calcium pattern analysis
- Where
- Belgium
- Volunteers
- 42 people
- Sponsor
- University Hospital, Ghent