Clinical trials: Oocyte Cryopreservation
In Vitro Fertilization
Corifollitropin Alfa Application in PCOS Patients
Corifollitropin alfa, single dose administered sustains multiple follicular development for 7 days. However, It may induce ovarian hyperstimulation syndrome (OHSS), especially in high responder women such as patients of…
- Trial name
- NCT02215135
- Testing
- Corifollitropin alfa
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Infertility
Oocyte Cryopreservation: Slow Cooling Versus Vitrification Techniques on Oocyte Survival
Oocyte cryopreservation has been studied for many years without much success in refining a method that has consistent, reliable results in producing viable embryos and clinical pregnancies.
- Trial name
- NCT00602966
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- UConn Health
Oocyte Cryopreservation
Paired Non-inferiority Study Comparing Overture Semi-automated Vitrification System ("DaVitri") to Standard Manual Process for Clinical Pregnancy Outcomes
This study will recruit 260 female recipients (and up to a maximum of 130 donors). This study is a sequel to the protocol CP-DV-000-GEN-003, entitled, "NON-INFERIORITY STUDY COMPARING OVERTURE SEMI-AUTOMATED VITRIFICATION SYSTEM…
- Trial name
- NCT06853418
- Testing
- Oocyte Cryopreservation
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Overture Life
Oocyte Cryopreservation
Optimization of Oocyte Warming Protocols
This is a retrospective study with a sibling design comparing new oocyte thawing protocols (rapid and ultra-rapid) with the traditional method
- Trial name
- OVOfast (NCT07105891)
- Testing
- Thawing protocol
- Where
- Italy
- Volunteers
- 399 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Infertility
Oocyte Cryopreservation: The Impact of Cryopreservation on the Meiotic Spindle and Mitochondria of Human Oocytes.
Our aims is to document the possible effect of cryo- preservation at the meiotic spindle and mitochondrial levels.
- Trial name
- WCFC (NCT00716118)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- West Coast Fertility Centers
Infertility
Oocyte Cryopreservation: Evaluation of an Oocyte Freezing and Thawing Technique
Over the past several decades, considerable effort has been expended toward the successful cryopreservation of various human cells.
- Trial name
- Slow-freeze (NCT00713869)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- West Coast Fertility Centers
Fertility Preservation
Oocyte Cryopreservation
The specific aim of this study is to further develop methods of oocyte cryopreservation and evaluate their impact on reproductive outcomes.
- Trial name
- NCT01696786
- Testing
- Oocyte cryopreservation
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Women Diagnosed With Cancer, Egg Donors
Oocyte Cryopreservation by Slow Freezing and Vitrification
This study seeks to evaluate whether the vitrification technique, as compared to the more traditional slow-cooling technique, leads to higher rates of successful thawing, fertilization, implantation and delivery.
- Conditions
- Women Diagnosed With Cancer, Egg Donors, Single Women, Failed Sperm Procurement in IVF
- Trial name
- NCT01223105
- Testing
- slow freeze, Vitrification
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Infertility
Oocyte Cryopreservation Comparing Fresh and Vitrified Sibling Oocytes
Vitrification is a method to cryopreserve biological specimens that are sensitive to chilling injury such as oocytes and embryos, and it has been employed with increased survival rate and live births (Hong et al., 1999; Kuleshova…
- Trial name
- NCT00986687
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- UConn Health
Fertility
Oocyte Cryopreservation
The purpose of this investigation is to offer the opportunity for young women to cryopreserve (freeze) their oocytes (eggs) for use with IVF at a later point in time.
- Trial name
- egg freezing (NCT01232972)
- Testing
- vitrification of oocytes
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Infertility, Female, Deferred Childbearing
Investigational Oocyte Cryopreservation for Medical and Non Medical Indications
This is a prospective study to assess the long term benefits and outcomes of the existing oocyte cryopreservation methods for fertility preservation in women with a potential medical or non medical risk of loss of fertility
- Trial name
- NCT04616417
- Testing
- Investigational Oocyte Cryopreservation
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Oocyte Cryopreservation
Oocyte Cryopreservation Registry (HOPE Registry)
Phase IV, prospective multicenter, observational Registry will track cycle outcomes for subjects who are thawing frozen oocytes for subsequent use through in vitro fertilization (IVF) and embryo transfer (ET)
- Trial name
- NCT00699400
- Where
- 15 sites in United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- EMD Serono
Infertility
Randomized Controlled Trial Comparing Slow-freezing to Vitrification of Oocytes
Preservation of fertility is limited. Current methods include embryo cryopreservation and while still experimental, ovarian cryopreservation.
- Trial name
- NCT00777387
- Testing
- slow-freeze, vitrification
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
ART, Child Development
Cognitive, Emotional, Communicative, and Motor Development in Children Born From IOC
The study focuses on children born after in vitro fertilization (IVF) of cryopreserved oocytes.
- Trial name
- NCT05906966
- Testing
- Phone contact
- Where
- Italy
- Volunteers
- 377 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Cancer
Oocyte Cryopreservation Study (Egg Banking)
Women of reproductive age who seek to freeze eggs for future pregnancy attempts may be eligible to participate in a study investigating pregnancies that result from frozen eggs.
- Trial name
- NCT02396095
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Fertility
Effect of Oocyte Vitrification on Fertilization Rate, Embryo Quality and Development
Indications for oocyte (egg) vitrification (fast freezing) include the preservation of reproductive competence of young cancer patients who need chemotherapy, pelvic radiation, or surgical removal of ovaries for treatment.
- Trial name
- NCT01422395
- Testing
- Freezing
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Main Line Fertility Center
Anxiety
The Effectiveness of Virtual Reality on Anxiety Reduction in Women Undergoing Elective Egg Cryopreservation.
A randomized trial assessing the effectiveness of virtual reality exposure prior to an oocyte retrieval procedure in terms of anxiety level .
- Trial name
- VRFORANXIETY (NCT06280222)
- Testing
- The VR instrument - Oculus Quest 2
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Infertility
Clinical Pregnancies After Cryopreservation of Donor Oocytes With an Open or Closed Device
This randomized pilot study will assess if there is a difference in clinical pregnancies using donor oocytes cryopreserved in either a closed or a semi-closed vitrification device.
- Trial name
- NCT02940106
- Testing
- Cryotop device, CBSvit device
- Where
- Belgium
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel